Beetroot extract · Beetroot Extract (Dietary Nitrate)
Concentrated dietary nitrate. Replicated blood-pressure and endurance effects — one of the few sports supplements that works.
Short answer
One of the best-evidenced supplements for blood pressure and recreational endurance. Standardized nitrate content is everything.
Product and dose overview
Beetroot extract (Beetroot Extract (Dietary Nitrate)) is a cardiovascular / performance with evidence grade B, meaning it is supported by human RCTs. We track 0 products containing Beetroot extract. The top-ranked product scores 0 out of 10 on our composite scale (dose, evidence, price, testing, transparency). Prices range up to $0.00 per month.
What it is
Concentrated red beetroot, valued for its nitrate content. Your body converts nitrate to nitric oxide, which widens blood vessels.
Why people take it
Dozens of trials show beetroot nitrate lowers blood pressure around 4-5 mmHg systolic and improves endurance efficiency by a few percent. The effect is real enough that Olympic programs use it. Benefits fade in elite athletes and when nitrate content is not standardized.
Our verdict
One of the best-evidenced supplements for blood pressure and recreational endurance. Standardized nitrate content is everything.
Structure & class
Beta vulgaris concentrate standardized for inorganic nitrate (NO3-). Reduced via oral bacteria to nitrite, then NO under low-oxygen conditions.
Mechanism & clinical data
Kapil et al. 2015 (Hypertension) RCT: 250 ml beetroot juice (~6 mmol nitrate) daily for 4 weeks reduced clinic systolic BP by ~7.7 mmHg in hypertensive patients, with sustained effect. Meta-analyses confirm ~4-5 mmHg systolic reduction and improved exercise economy at 5-9 mmol nitrate. Antibacterial mouthwash abolishes the effect — oral microbiome required.
Pharmacokinetics
Nitrite peaks 2-3 hours post-dose; daily dosing sustains BP effect.
Dose & forms
What to watch out for
Generic 'beetroot powder' may contain almost no nitrate — look for standardized nitrate content (300-400 mg per serving). Avoid antibacterial mouthwash around dosing or you lose the effect.
Where this dose comes from
The trial dose above is our editorial pick from the published human trials for this ingredient. We choose the dose that the best-available studies used on the endpoint most relevant to longevity. The range shows the lowest and highest doses tested in published trials. The landmark studies below are the papers we read to set it. You can click through and check our work.
When new trials publish, our automated sweeps flag them. If a new study materially changes the dose, we update it through editorial review and record the old dose, new dose, and the triggering study in every affected product's recommendation history. The dose is never changed automatically.
Regulatory status
Timeline
Regulatory events, evidence grade changes, and key research milestones for Beetroot extract, most recent first. Studies link to the paper; regulatory entries name and link the responsible authority.
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EU Court sharpens the bar for botanical health claimsA Court of Justice of the European Union ruling in April 2025 further tightened the requirements for how botanical ingredients (herbs, plant extracts) can be marketed with health claims in the EU, effectively removing much of the flexibility of the on-hold list.
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EU report identifies 117 supplement substances as potential health risksThe HoA Working Group on Food Supplements (26 European countries) published its first report evaluating 117 substances used in food supplements. Of these, 65 were assessed as likely novel foods, 6 were already regulated, 34 had insufficient data, and 12 were prioritized for Article 8 restriction under Regulation (EC) No 1925/2006. The 12 priority substances include ashwagandha, curcumin, melatonin, piperine, St. John's wort, coumarin, p-synephrine, maca, holy basil, Melaleuca, black cohosh, and L-tryptophan. The report drew on 1,500 RASFF alerts reviewed between 2017 and mid-2022.
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Kapil et al. 2015 (Hypertension)RCT in hypertensive patients: daily dietary nitrate from beetroot juice produced sustained systolic BP reduction (~7.7 mmHg clinic, ~5+ mmHg ambulatory) over 4 weeks.
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EU Health Claims Regulation adoptedRegulation (EC) No 1924/2006 laid down harmonised rules for nutrition and health claims made on foods, including supplements. Only claims listed in the EU Register of authorised claims can be used. Rejected botanical claims are held in a separate on-hold list.
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EU introduces the Novel Food RegulationRegulation (EC) No 258/97 required any food or food ingredient without a history of consumption in the EU before 15 May 1997 to be authorised before being placed on the market. This is the framework that captures NMN, spermidine as a supplement ingredient, urolithin A, and many other longevity actives.
Landmark studies
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Kapil et al. 2015 (Hypertension)
RCT in hypertensive patients: daily dietary nitrate from beetroot juice produced sustained systolic BP reduction (~7.7 mmHg clinic, ~5+ mmHg ambulatory) over 4 weeks.
Read study →
Found in these products
All products in our catalog that contain Beetroot extract, ranked by our overall score. Ranking is editorial, never paid.
No products in our catalog contain this yet.
Buying guides and comparisons
Related ingredients
See all in Cardiovascular / Performance →Molecules in the same class, plus the actives most often formulated alongside Beetroot extract in our catalogue.
See Beetroot extract in context: the mechanism it acts through, the biomarker it moves, the products that dose it, and the trials that tested it.
View Beetroot extract on the Longevity Map →Frequently asked questions
What is Beetroot extract?
Concentrated red beetroot, valued for its nitrate content. Your body converts nitrate to nitric oxide, which widens blood vessels.
What dose of Beetroot extract should I take?
The trial dose in published human studies is 400 mg per day, with a range of 300 to 800 mg per day. Always consult a qualified clinician before starting any supplement.
Is Beetroot extract safe?
Generic 'beetroot powder' may contain almost no nitrate — look for standardized nitrate content (300-400 mg per serving). Avoid antibacterial mouthwash around dosing or you lose the effect.
What is the best Beetroot extract supplement?
We track 0 products containing Beetroot extract. The top-ranked product scores 0 out of 10 on our composite scale, which evaluates dose, evidence, price, third-party testing, and transparency. See the comparison table above. Scores are editorial judgments, not a scientific standard.
What is the evidence grade for Beetroot extract?
Beetroot extract has evidence grade B, meaning it is supported by human RCTs. Grade A means replicated human RCTs with hard endpoints. Grade B means human RCTs with biomarker outcomes. Grade C means mixed or small human trials. See our evidence grading methodology.
Data verification
Evidence grades are reviewed when new human RCTs are published. Product counts update automatically as new products are added. Dose ranges reflect published trial data, not brand recommendations. Read how we verify.