Every time new research changes something on this site, it appears here. What changed, when it changed, and what it links to. No source names, no hidden edits.
Mechanistic sub-study, N=30 knee osteoarthritis patients: 80 mg/day nano-micelle curcumin for 3 months reduced T-bet gene expression and correlated with CD8+ T cell frequency. GATA3 unchanged. Explain
Phase 2 trial will test AV078, a selective mTORC1 inhibitor, in 42 participants aged 12 and older with refractory epilepsy due to tuberous sclerosis complex. Sponsor Aeovian Pharmaceuticals. Not yet r
FDA posted warning letters to three peptide sellers in August and September 2026: Empower Pharmacy (September 18), Tex Peptides (August 24) and Peptide Partners (August 24). The letters state the comp
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PROTOCOL CHANGE / CONTROVERSY: the daily “My Rx stack” entries shown in the 23 Sep snapshot, including metformin 500 mg in six-week cycles and acarbose 200 mg, are now absent; the separate prescriptio
N=1 BIOMARKER UPDATE: Johnson reported sleep down 15%, an undefined “nervous system” metric down 17%, and resting heart rate up 16% after 5 days near 7,000 ft; on his first sea-level night he reported
N=1 ENVIRONMENTAL MEASUREMENT: Johnson reported 4,900 spores/m³ in his gym, including 4,800 Penicillium/Aspergillus and about 40 Ulocladium, versus an outdoor control of 360; no clinical outcome was r
Phase 2 trial will test propranolol, desloratadine and magnesium plus vitamin D as adjuncts to cancer immunotherapy in 46 patients, University of Southern California. Starts November 2026. Not yet rec
Phase 1/2 trial of intermittent fisetin senolytic dosing in 70 adults aged 65 and older to improve vascular endothelial function and reduce aortic stiffness. Primary completion was March 2026. Registr
Phase 2 trial planned 89 adults with NASH on berberine vs placebo, Fudan University. Registry status: terminated. Primary completion was November 2024, no results published.
Volume 81 Issue Supplement_1 | The Journals of Gerontology: Series B | Oxford Academic Volume 81, Issue Supplement_1 February 2026 Cover image EISSN 1758-5368 - Editorial ... - Research Articles ...
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https://doi.org/10.1093/geronb/gbaf253 Advance access publication 14 January 2026 Supplement: Harmonization Recommendations from the Gateway to Global Aging Data: Research Article Sharing common meas
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pISSN: 1549-1684• eISSN: 1557-8577• Mary Ann Liebert, Inc.• United States Save journalShare…Checking system sharing availability. ... 2026 Journal Metrics Score 1.5 Updated August 2026 · 2-year citati
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Journal Abbreviation: REJUV RES Journal ISSN: 1549-1684 ### About Rejuvenation Research |Year|Impact Factor (IF)|Total Articles|Total Cites| |--|--|--|--| |2025 (2026 update)|1.8|-|2001| |2024|2.6|-|2
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## What to know - Rigorous new human research found whole-blood NAD+ levels don't decline with age, challenging the core premise behind NAD+ supplements, including NMN. - The clinical evidence that NM
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A new clinical trial in Nature Aging shows that Urolithin A can rejuvenate the aging immune system by improving mitochondrial health. ... ## What to know - A new Nature Aging clinical trial found that
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## Key takeaways - Nestlé clinical research found NR and NMN both effectively increase circulatory NAD+ levels in healthy adults within 14 days. - Supplementation improves gut health by promoting micr
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And new research suggests that part of the thinking that helped to fuel the booming market for these supplements may be wrong. A study published this month in Nature Metabolism showed that blood level
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The Spanish biochemist Juan Carlos Izpisua, who has spent decades working in the United States seeking his own answer, has outlined a new view: “Aging,” he says, “is a loss of identity at the cellular
A *Nature Metabolism* study confirmed that both NMN and NR double circulating NAD+ levels in 14 days. ... Key Takeaways - Life Biosciences received FDA IND clearance in 2026 to test ER-100, the first-
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**FDA clearance for IND (January 28th): ** Life Biosciences (THE company people associate with reprogramming, co-founded by Longevity Superstar Dr David Sinclair) received FDA clearance for its IND ap
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2026 年，消费者选购 NMN 时最关心的问题已经从 “NMN 是不是智商税” 转变为 “什么样的 NMN 才真正有效”，而 2025 年发表在国际顶级学术期刊《Nature Aging》上的一项大样本 NMN 临床研究，恰好给行业和消费者提供了明确的参考标准。对于有长期健康管理需求、注重生活品质的消费群体而言，选对符合权威科研标准的 NMN 产品，才是抗衰投资不踩坑的核心前提。 ... 这篇由
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Rejuvenation Research publishes cutting-edge, peer-reviewed research on rejuvenation therapies in the laboratory and the clinic. The Journal focuses on key explorations and advances that may ultimatel
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(Based on the publications from the last 4 years) (from 2022-05-01 to roughly 2026-05-01) |Number of papers|139| ... |H4-Index|12| |TQCC|3| |Average citations|3.266| |Median citations|1| |Impact Facto
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**Biomarkers of Neurodegeneration**: The latest joint Series from *eBioMedicine*and *The Lancet Healthy Longevity*seeks to highlight the roles of biomarkers of neurodegeneration in a multitude of cont
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Senescent cells — "zombie cells" that stop dividing but refuse to die — accumulate with age and secrete inflammatory molecules called the SASP. Fisetin, a flavonoid found in strawberries and apples, w
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🚨 The February 2026 issue of eBioMedicine is now live! This month, we spotlight a question at the heart of modern medicine and longevity science: can we measure biological age in a way that truly impr
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Cellular Rejuvenation Has the Potential to Reverse Aging - The New York Times ... To understand this process, which was discovered only recently and is known as “natural rejuvenation,” is to contempla
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September 10, 2026 · Baton Rouge, LA ### Published in Cell Metabolism, the paper suggests protein restriction triggers a coordinated whole-body response that may help explain its effects on healthy ag
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|Primary Mechanism|Evidence Tier|Typical Dose|Naturecan Product| ... |Urolithin A|Mitophagy / immune ageing|Strong (2025 Nature Aging RCT)|500 mg/day| ... The MitoImmune trial (Nature Aging, 2025) exa
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News/July 10, 2026 # Analysis finds longevity diet promotes fat loss in mice despite increased food intake — Evidence Review Published in Cell Metabolism, by researchers from University of Southern Ca
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*The Journals of Gerontology: Series B*, gbag199, https://doi.org/10.1093/geronb/gbag199 Published: 25 September 2026 **Section: ** Research article - Abstracts ** ... *The Journals of Gerontology: Se
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Multiple strategies, including metabolic modulation (e.g., physical exercise, calorie restriction, and calorie restriction mimetics), targeting inflammaging, senotherapy, parabiosis, stem cell-based t
A daily multivitamin–multimineral supplement significantly slowed certain markers of biological ageing after 2 years of treatment in a study involving 958 older adults. The results, published in *Natu
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Volume 81 February 2026 … ... *The Journals of Gerontology: Series B*, Volume 81, Issue Supplement_1, February 2026, Pages S18–S30, https://doi.org/10.1093/geronb/gbaf200 Published: 21 October 2025 Ar
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Browse supplements Volume 81, Issue 7 July 2026 Cover image ... ##### Effects of a short-term multicomponent functional exercise program on the serum proteome: an exploratory study in hospitalized old
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## Aging appears to trigger a major biological transformation in the human brain beginning around midlife. ... September 15, 2026 ... Scientists have uncovered sweeping changes in how the human brain
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## Blocking one immune-cell receptor helped old mice stay leaner, stronger, sharper, and biologically younger across multiple organs. ... September 3, 2026 ... Aging may be partly fueled by immune cel
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A naturally occurring compound found in foods such as wheat germ, mushrooms, and aged cheese may help older adults build stronger protection after vaccination. In a small pilot trial, researchers gave
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July 9, 2026 ... Scientists found that a modified Mediterranean-style diet with low protein and just enough methionine helped mice live healthier lives while reducing body fat and frailty. Human data
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Researchers are now exploring ways to boost NAD⁺ using compounds like NR and NMN, with early studies hinting at improvements in memory, metabolism, and physical function. ... The review examines years
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## A 7-million-cell atlas reveals that aging is a synchronized, body-wide process that may finally be within reach of targeted therapies. ... February 28, 2026 ... Scientists have built a massive cell
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# The Lancet on X: "A study in The Lancet Healthy Longevity found that stopping statins in adults over 75 with no history of heart disease or stroke does not increase the risk of death within three ye
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Published 13 March 2026 Updated 28 August 2026 By World Longevity Clinics Editorial Team NAD+ precursor supplementation in human ageing: clinical evidence and challenges ... The Nature Metabolism revi
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Seeing the USP Verified Mark on a dietary supplement label indicates that the product: **Contains the ingredients listed on the label, in the declared potency and amounts**. Tests have shown that cont
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Dr. Rhonda Patrick reviews urolithin A, microbial conversion, mitophagy, and human trials of muscle function and supplementation. ... Posted on April 3rd 2026 (6 months) Dr. Rhonda Patrick reviews mul
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VOTE ... VOTE - Medicinal Mushrooms 6714 Votes ... - Milk Thistle 11058 Votes ... VOTE ... VOTE - Tribulus Terrestris 6798 Votes ... - Turmeric 11956 Votes ... VOTE
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### USP (United States Pharmacopeia) USP is a nonprofit organization that sets official standards for medicines, supplements, and food ingredients used in the United States. The USP Verified mark indi
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Posted on August 21st 2026 (about 1 month)
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Certified Product Results | NSF International Certified for Sport® ... 2. Certified Products Search 3. Search Results ... ## to stay up-to-date on the latest certified products
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Rhonda — Articles, Videos, & Studies | FoundMyFitness …
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Supplement Rankings - Labdoor ... #### Labdoor has tested and ranked 44 supplement categories.
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Quality Ranking Value Ranking A-Z ##### RANKING ... There are no products that match all your filters.
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Last updated on 21 Apr, 2026 Learn more about what’s included in Examine’s current subscriptions below. ... Contact or email us at support@examine.com for help. ... Interactions, side effects, precaut
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Last updated on 30 Apr, 2026 # Subscriptions and offers ... - Evidence-based nutrition and supplement insights to help you make informed decisions for your own health. Includes the Examine Database, S
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Published Jun 25, 2026 ... It’s not that we haven’t been slowly chipping away, keeping our pages up-to-date, and adding new content, but our small team has had our efforts focused on things like the S
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FoundMyFitness Episodes - Proven protocols for strength and muscle building - Nutritional and supplement strategies
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USP’s Dietary Supplement Verification Program is open to manufacturers of dietary supplement finished products from around the world. USP verifies dietary supplements containing vitamins like B, C, D,
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Dr. Rhonda Patrick reviews vitamin D, omega-3s, multivitamins, magnesium, creatine, and melatonin for adults over 65.
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Independent Tests and Reviews of Vitamin, Mineral, and Herbal Supplements - ConsumerLab.com # Find the best supplements and foods — based on independent tests of quality. ... ## 32% Failed Our Tests.
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539 • 4.6 Sports Nutrition Store ... Looking at 378 reviews, reviewers overwhelmingly had a great experience with this company. People frequently praise the exceptional quality of the fitness products
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HealthRX.com quick answer. Most NMN and NR users on Reddit and supplement forums report mild or no side effects at doses between 250 mg and 1,000 mg daily. The most common complaints are GI discomfort
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de.pipingrock.com•105 reviews #### 3.0 1. Beauty & Well-being 2. Personal Care ... 2.4 ... Evaluating 58 reviews, most reviewers were unhappy with their experience overall. Customers frequently compla
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1,977 • 4.5 Vitamin and Supplements Store ... Evaluating 1,743 reviews, reviewers overwhelmingly had a great experience with this company. Customers frequently mention how wonderfully easy it is to in
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# Gold Seal Supplements Reviews 567 • 4.1 Vitamin and Supplements Store ... Looking at 547 reviews, reviewers had a great experience with this company. Customers frequently praise the effective produc
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**subreddit: /r/Supplements** ... ### Does MITOLYN Reviews 2026 (Tried for 365 Days) My Honest Review!
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*13th Aging Research & Drug Discovery Meeting will convene leaders from pharma, biotechnology, academia, clinical medicine, investment, AI and policy October 1–3 at the David Rubenstein Treehouse at H
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#### GSA 2026 in National Harbor, MD Join your colleagues at the premier Annual Scientific Meeting for fields related to gerontology. ... #### Free registration with booth purchase! Reserve your 2026
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ARDD Program 2026 ARDD Program 2026 OCTOBER 1-3, 2026 David Rubenstein Treehouse at Harvard University October 1 October 2 October 3 ## October 1 Thursday · Canopy Hall, 3/F, David Rubenstein Treehous
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PX Health Longevity Summit 2026 – Gesundheitskongress in München ... Der Longevity Summit von PX Health ist ein wegweisendes Event im Herzen Münchens, das am **13** **. bis 15. November 2026** stattfi
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## GSA 2026 Scientific Meeting November 4 - 7 | National Harbor, MD. Visit gsa2026.org ### Important Updates **Standard Registration—** September 2 - November 7—Register Now **Now Open— ** Register |
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*Panel at Harvard University will explore translating evidence in diseases of aging into new therapeutics and regulatory pathways* SEATTLE, Sept. 24, 2026 /PRNewswire/ -- Atossa Therapeutics, Inc. (Na
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#### Sep 28 - Kowloon, Hong Kong **Register Now!**
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- ICBMS 2026: Biological and Medical Sciences Conference, Amsterdam (Jan 19-20, 2026) - ICBMS 2026: Biological and Medical Sciences Conference, Bangkok (Jan 19-20, 2026) - ICGGP 2026: Gerontology and
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Gerontological Society of America • 2026 Annual Scientific Meeting Gerontological Society of America (GSA) 2026 Annual Scientific Meeting Reinforcing Resilience in Aging Science, Research, and Educ
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1985 New York NY USA ## History ... Promote biomedical *aging* studies directed towards increasing the functional life span of humans; keep the public informed of the progress of aging research and of
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This year we have an incredibly exciting program with global thought-leaders sharing their latest insights into aging and how we target aging process ensuring everyone lives a healthier and longer lif
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Tai Chi/Qi Gong and Alpha Lipoic Acid with or without Acupuncture for the Treatment of Chemotherapy-Induced Peripheral Neuropathy for Patients with Stage I-III Colorectal Cancer - NCI 1. Home ... # Ta
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April 1, 2026 ... Researchers at the University of Arizona R. Ken Coit College of Pharmacy will begin a double-blind, randomized Phase 3 clinical trial this year to evaluate whether a drug used to pre
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### Age range 18 year–65 year ### Sex eligibility All sexes ### Study type Interventional ### Phase Not applicable ### Primary location ### Poznan University of Life Sciences Poznan, Wielkopolska, 60-
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Based on a randomized controlled trial of berberine (registered in ClinicalTrials.gov on Dec 2018, NCT03770325), leveraging proteomics and sex hormones data, we built a signature reflecting response t
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This systematic review evaluates the efficacy and safety of oral magnesium supplementation compared to placebo or standard care (sodium valproate) for migraine prophylaxis. ... We analyzed randomized,
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This trial will investigate whether high-dose spermidine improves cardiac remodelling, exercise capacity, muscle mass, and systemic inflammation in elderly patients with CAD. ... This is a single-cent
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Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials Nutrition Journal Received: 12 Septemb
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The effects of oral magnesium supplements on vascular and endothelial function: an updated systematic review and meta-analysis of randomized controlled trials | BMC Cardiovascular Disorders | Springer
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## RBR-78bcfbc Effect of Curcumin on gut health and inflammatory aspects in Overweight and Obese individuals Date of registration: 07/08/2026 ^(mm/dd/yyyy)^ Last approval date : 07/08/2026 ^(mm/dd/yyy
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## RBR-4cdm4k4 Study evaluating the effect of resveratrol on pain in women with lipedema Date of registration: 07/03/2026 ^(mm/dd/yyyy)^ Last approval date : 07/03/2026 ^(mm/dd/yyyy)^ ### Study type:
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## RBR-2g8tk6t Effects of resveratrol on heart health after exercise in menopausal women Date of registration: 04/22/2026 ^(mm/dd/yyyy)^ Last approval date : 04/22/2026 ^(mm/dd/yyyy)^ ### Study type:
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## RBR-2b7hw6b Impact of Resveratrol on the health of individuals with type 2 Diabetes Date of registration: 06/06/2026 ^(mm/dd/yyyy)^ Last approval date : 06/06/2026 ^(mm/dd/yyyy)^ ### Study type: In
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Clinical Trial Protocol Iranian Registry of Clinical Trials 23 Sep 2026 Studying the effect of resveratrol compared to placebo on ventricular and supraventricular arrhythmias in patients with implanta
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**Results:** Urolithin A: 1 peer-reviewed systematic review and 10 human randomized studies were identified, including 9 placebo-controlled efficacy/safety trials with approximately 392 randomized par
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## Palvella Therapeutics Announces First Patients Dosed in Phase 2 LOTU Trial of Fast Track-Designated QTORIN™ Rapamycin for Clinically Significant Angiokeratomas May 4, 2026 ... *Phase 2 single-arm,
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Palvella Therapeutics, Inc. () announced that it received a third year of grant funding from the FDA Office of Orphan Products Development to support the Phase 3 SELVA trial and ongoing open-label ext
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# Clinical Trials Using Nicotinamide Riboside Review the clinical trials studying nicotinamide riboside on this list and use the filters to refine the results by age and location. Some clinical trials
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Clinical Trials/NCT07842146 NCT07842146Not yet recruitingNot Applicable # A Phase II Clinical Trial on the Effect of a Mitophagy Inducer Urolithin A on Alzheimer's Disease University Hospital, Akershu
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## The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health ClinicalTrials.gov ID ** NCT07760506 Sponsor ** Applied Science & Performance Institute Information
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ClinicalTrials.gov ID ** NCT07703137 Sponsor ** University of Oklahoma Information provided by ** University of Oklahoma (Responsible Party) Last Update Posted ** 2026-07-14 **Not yet recruiting** **
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## A Clinical Trial to Assess the Absorption, Safety, and Efficacy of an Oral Nicotinamide Adenine Dinucleotide (NAD+) Supplement in Healthy Adults ClinicalTrials.gov ID ** NCT07692633 Sponsor ** Reus
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## Effects of Miricell Supplementation on Biomarkers of Healthy Aging and Autophagy ClinicalTrials.gov ID ** NCT07675200 Sponsor ** Nutraland USA, Inc. ... Last Update Posted ** 2026-06-30 **Recruitin
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## Assessment of the Effects and Safety of Spermidine Supplementation on Blood Lipids and Body Weight in Overweight or Obese Individuals With Hyperlipidemia ClinicalTrials.gov ID ** NCT07662330 Sponso
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## Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients (ALA-MYO-PCOS) ClinicalTrials.gov ID ** NCT07630779 Sponsor ** Beni-Suef University Information provided by **
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RecruitingNCT07592767RESETUpdated Sep 18, 2026 # RESvEraTrol in Parkinson's Disease (RESET) A Phase 2 interventional study of Trans-Resveratrol in Parkinson's Disease, sponsored by Georgetown Universi
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## Effectiveness of Oral Magnesium Supplementation in Fibromyalgia Patients Not Responding to Standard Treatment ClinicalTrials.gov ID ** NCT07585045 Sponsor ** Shaikh Zayed Hospital, Lahore ... Last
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Recruiting** ## Mechanistic Study of Nicotinamide Riboside on NAD+ Biology in Individuals With Combined Pulmonary Hypertension ClinicalTrials.gov ID ** NCT07563322 Sponsor ** Vanderbilt University Med
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Completed** ## Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men (HIITCRECOG) ClinicalTrials.gov ID ** NCT07534293 Sponsor ** U
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Completed** ## Effect of Curcumin Add-On Therapy on Quality of Life and IL-1β Levels in Patients With Schizophrenia (CUR-SCZ) ClinicalTrials.gov ID ** NCT07523256 Sponsor ** Rinvil Renaldi ... Last Up
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## Short-Term Safety of Low-Dose Creatine Hydrochloride: A 28-Day Single-Arm Pilot Study ClinicalTrials.gov ID ** NCT07521059 Sponsor ** Vireo Systems, Inc. ... Last Update Posted ** 2026-04-09 **Comp
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## Effect of Magnesium Supplementation on Sleep Quality and Cognitive Function in Saudi Adults ClinicalTrials.gov ID ** NCT07515417 Sponsor ** Umm Al-Qura University ... Last Update Posted ** 2026-08-
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Not yet recruiting** ## Effects of Short-term Acute Creatine Supplementation on Power, Speed and Muscular Strengths in Young Football Players ClinicalTrials.gov ID ** NCT07475676 Sponsor ** St. Mary's
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## Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat ClinicalTrials.gov ID ** NCT07472426 Sponsor ** University of Northern Iowa I
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## Study on the Efficacy of Quercetin Intake in Patients With Fibrotic Interstitial Lung Diseases. ClinicalTrials.gov ID ** NCT07466420 Sponsor ** Katerina M. Antoniou ... Last Update Posted ** 2026-0
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Not yet recruiting** ## Berberine Phytosome for Signs and Symptoms of Polycystic Ovary Syndrome (PCOS) ClinicalTrials.gov ID ** NCT07465575 Sponsor ** Liaquat University of Medical & Health Sciences I
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Not yet recruiting** ## Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease C
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Curcumin in Critically Ill Patients With Sepsis — NCT07436130 | ClinicalTrials.gg Home/Sepsis/NCT07436130 RecruitingNCT07436130Updated Sep 17, 2026 # Curcumin in Critically Ill Patients With Sepsis An
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RecruitingNCT07383311SpSleepUpdated Jul 2, 2026 # Autophagy-Enhancers to Reduce Sleep Disturbances An interventional study of Spermidine Supplementation and Dietary Placebo in Mild Cognitive Impairmen
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Active, not recruiting** ## Photobiomodulation Therapy vs. Alpha-Lipoic Acid in Burning Mouth Syndrome Treatment ClinicalTrials.gov ID ** NCT07381361 Sponsor ** Lu Jiang ... Last Update Posted ** 2026
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## Evaluation of the Pharmacokinetics of Curcumin Capsules in Healthy HumanClinicalTrials.gov ID ## Study Overview Main objective: Through blood drug concentration testing, evaluate the post-meal phar
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## Influence of the Urolithin A on the Population With BMI Higher Than 30 During Restricted Eating. (Obesity UroA) ClinicalTrials.gov ID ** NCT07377136 Sponsor ** Charles University, Czech Republic In
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Furthermore, metformin improves lifespan in animal models through an anti-ageing pathway driven by mTOR. Metformin has also been shown to protect endothelial cells from hyperglycaemic damage by direct
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Clinical Trials/NCT07284225 NCT07284225CompletedNot Applicable # Efficacy of a Single Dose of Nicotinamide Riboside (NR) on Sleep: A Randomized Controlled Study Eye & ENT Hospital of Fudan University1
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# Sirtuin Activator Effects on Metabolism in Overweight Women Study Aim This study aims to observe the effects of a sirtuin activator on metabolism and ageing biomarkers, such as telomere length and b
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## Magnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC) ClinicalTrials.gov ID ** NCT07149649 Sponsor ** Swiss Cancer Institute Information provided by ** Swiss Cancer Institute (Re
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## Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults ClinicalTrials.gov ID ** NCT07144527 Sponsor ** Scott Silveira ... Last Update Posted ** 2026-
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## Comparisons of NAD Precursors for Neuroenhancement in Glaucoma Patients ClinicalTrials.gov ID ** NCT06991712 Sponsor ** Christopher Kai Shun Leung ... Last Update Posted ** 2025-06-26 ... The goal
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## Creatine and Resistance Training in Older Adults With Mild Cognitive Impairment ClinicalTrials.gov ID ** NCT06948149 Sponsor ** Western University, Canada ... Last Update Posted ** 2026-05-19 **Rec
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## Intervention of Nicotinamide Mononucleotide in Middle-aged and Elderly People (NMNAGING) ClinicalTrials.gov ID ** NCT06592859 Sponsor ** People's Hospital of Quzhou Information provided by ** Feng
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NAD+ Oral Supplement Pilot Intervention in... | Clinical Trial Clinical Trials/NCT06579209 NCT06579209CompletedNot Applicable # NAD+ Oral Supplement Pilot Intervention in Adult Females University of R
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Clinical Trials/NCT06350890 NCT06350890CompletedPhase 3 # A Multicenter, Randomized, Double-blind, Placebo-controlled Phase 3 Study Evaluating the Efficacy and Safety of HTD1801 in Patients With Type
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Effects of Quercetin on Cardiometabolic... | Clinical Trial Clinical Trials/NCT06230861 NCT06230861RecruitingNot Applicable # Effects of Quercetin Supplementation on Cardiometabolic Parameters Univers
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## Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction ClinicalTrials.gov ID ** NCT06195306 Sponsor ** National Cancer Institute (NCI) Information provided by ** Na
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## Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative NeoplasmsClinicalTrials.gov I
Completed** ## Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression ClinicalTrials.gov ID ** NCT05774665 Sponsor ** Massachusetts General Hospital ... Last Update Posted ** 202
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Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity — NCT05713799 | ClinicalTrials.gg ... Not yet recruitingNCT05713799Updated Sep 25, 2026 # Trial of the Com
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## Fisetin to Improve Physical Function in Stage I-III Breast Cancer SurvivorsClinicalTrials.gov ID ## Study Overview PRIMARY OBJECTIVE: I. To determine the effect of fisetin on physical function, as
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Recruiting NA INTERVENTIONAL 1-arm NCT05095571 # A Trial of Nicotinamide/Pterostilbene Supplement in ALS: The NO-ALS Extension Study A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbene
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The primary objectives are to: - To determine whether MIB-626, after its daily oral administration, penetrates the blood-brain barrier in humans by measuring the cerebrospinal fluid (CSF) concentratio
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Clinical Trials/NCT04571008 NCT04571008CompletedNot Applicable # Effect of Nicotinamide Mononucleotide (NMN) Supplementation on Organ System Biology Washington University School of Medicine1 site in 1
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Active Not Recruiting NA INTERVENTIONAL 2-arm NCT04562831 # The NO-ALS Study: A Trial of Nicotinamide/Pterostilbene Supplement in ALS. A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbe
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Nicotinamide riboside Phase 2 — 1 site, updated Aug 2026 | DataLookout 1. Home ... # NIAGEN and Persistent Chemotherapy-Induced Peripheral Neuropathy **Status** Active, Not Recruiting **Phase** Phase
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## Omega-3 Fatty Acid in Treating Patients With Stage I-III Breast CancerClinicalTrials.gov ID ... PRIMARY OBJECTIVES: I. To determine if omega-3 dietary supplementation (omega-3 fatty acid) results i
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## Vitamin D and Omega-3 Trial (VITAL) (VITAL) ClinicalTrials.gov ID ** NCT01169259 Sponsor ** Brigham and Women's Hospital ... Last Update Posted ** 2026-07-30 **Active, not recruiting** ** No longer
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### Age range 18 year and older ### Sex eligibility All sexes ### Study type Interventional ### Phase Phase 1 ### Primary location Brigham and Women's Hospital, Boston, Massachusetts, United States Lo
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Metformin's Aging Trial Has Never Enrolled a Patient ... TAME has no registration and has never begun. Its closest randomized test followed 3,234 adults without diabetes for 21 years and found no surv
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# Metformin Shows Promise for Slowing Cellular Aging in Prediabetic Adults Six-month trial examines whether metformin treatment can improve telomere length and longevity gene expression in prediabetic
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Now, a new Indian study suggests the decades-old, inexpensive drug may be doing something far more than lowering blood sugar — it could be slowing down the biological clock inside human cells. The 24-
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Metformin anti-aging protocols show 20-30% lifespan extension in studies. ... In This ArticleHow Metformin Works for Anti-AgingClinical Evidence from Human StudiesOptimal Dosing Protocols for Longevit
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This trial will test the hypothesis that geroprotectors targeted towards biological mechanisms associated with poor resilience can reverse these pathways within a three-week period. Three geroprotecto
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Last reviewed: 2026-04-12Version 1Next review: approx. 12 monthsForm studied: Oral L-glycine at 3 g taken before bedtime for sleep outcomes; doses of 5–15 g/day studied for metabolic outcomes SummaryI
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Glycine Extends Life & Counters Brain and Muscle Degeneration, New Study Shows ... Glycine, an amino acid shown to extend the lifespan of mice, moderately extends the lifespan of flies and counters br
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Urolithin A (UA), a gut microbiota–derived metabolite, has been proposed to improve skeletal muscle function, but evidence from randomized controlled trials has not been systematically summarized. Thi
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Neurol., 10 August 2026 ... Volume 17 - 2026 | https://doi.org/10.3389/fneur.2026.1904967 … The PubMed, Embase, Web of Science, Cochrane Library, and Scopus databases were systematically searched (up
Last updated: April 11, 2026 Sponsor: Northwestern University Overall Status: Active - Recruiting #### Phase 2 #### Condition Vascular Diseases Intermittent Claudication Circulation Disorders #### Tre
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Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors | Clinical Research Trial Listing 1. Study # Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors Las
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Scientists revealed that the drug could have potential to become the first neuroprotective treatment in multiple sclerosis (MS). But they stress that people should not attempt to acquire alpha-lipoic
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### Age range 45 year–75 year ### Sex eligibility All sexes ### Study type Interventional ### Phase Not applicable ### Primary location ### Washington University School of Medicine St Louis, Missouri,
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# Clinical Trials Using Curcumin Review the clinical trials studying curcumin on this list and use the filters to refine the results by age and location. Some clinical trials are held at NCI-Designate
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|Unique ID issued by UMIN|UMIN000062041| ... |Receipt number|R000070989| |Scientific Title|Single-ingredient Vitamin D3 3200 IU versus Vitamin D3 3200 IU/Zinc/Quercetin Supplementation in Adult Indone
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ing metabolic, cardiovascular, inflammatory, and oncological disorders. Spanning Early Phase 1 through Phase 4, these studies encompass active recruiting, completed, and terminated statuses, and are s
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Benefits of Nicotinamide Riboside Upon Cognition and Sleep | Clinical Research Trial Listing 1. Study # Benefits of Nicotinamide Riboside Upon Cognition and Sleep Last updated: September 23, 2026 Spon
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Low‐Dose Fisetin Supplementation and Its Association With Chronic Inflammation in Middle‐Aged and Older Adults: Study Protocol for a Triple‐Blind, Randomised, Placebo‐Controlled Trial - Tavenier - 202
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|Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally…NCT06100276|Sep 30, 2026 · Estimated|Phase 1/2| ... Live trial data Data as of 2026-09-28, ClinicalTrials.gov 313 active trials,
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Basis (nicotinamide riboside/pterostilbene) / Elysium Health ... ## A Trial of Nicotinamide/Pterostilbene Supplement in ALS: The NO-ALS Extension Study (clinicaltrials.gov) - P=N/A | N=300 | Active, n
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September 16, 2026 ## Discovery of Forvisirvat (DS-7830a/SP-624), a Brain-Penetrant Sirtuin 6 Activator Derived from Griseofulvin with Antidepressant-Like Effects. ... Forvisirvat selectively activate
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Effects of Oral Taurine Supplementation on Cardiometabolic Risk Factors: A Meta-analysis and Systematic Review of Randomized Clinical Trials | Nutrition Reviews | Oxford Academic ... Volume 84 Issue
Project Details # TauAge randomised, controlled pilot trial: Does taurine supplementation with 4 g/day for 6 months slow human ageing? Subject Area Biogerontology and Geriatric Medicine Term since 202
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Jeyakodi S et al. Int J Clin Trials. 2026 Aug;13(3):270-282 https://www.ijclinicaltrials.com ... Original Research Article Metaberine (bio-optimised berberine 200 mg/day) improves metabolic health mar
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Status: Enrolling # Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial Phase II Age ≥18 Sponsor National Cancer Institu
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- **Turn Biotechnologies** acquired ARMMs vesicular delivery technology (March 2025) and plans clinical trials for skin rejuvenation in 2026 - **Life Biosciences** (founded by David Sinclair) is enter
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*Curr. Issues Mol. Biol.* **2026**, *48*(2), 216; https://doi.org/10.3390/cimb48020216 Submission received: 17 January 2026 / Revised: 13 February 2026 / Accepted: 15 February 2026 / Published: 16 Feb
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We review the current SIRT modulator pharmacological toolkit—including EX-527, OSS_128167, and emerging SIRT7-selective inhibitors—and identify the substantial clinical translation gap, with no SIRT-t
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Reduced nicotinamide mononucleotide (NMNH) is a reduced NAD⁺ precursor with reported NAD⁺- augmenting activity in preclinical models; however, controlled human data remain limited. This was a randomiz
Berberine shows no advantage over placebo for reducing liver and belly fat January 28, 2026 ... Credit: *JAMA Network Open* (2026). ... A multicenter research effort in China conducted clinical trial
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Randomized, Double-blinded, Placebo-controlled Study Evaluating the Efficacy of Nicotinamide Riboside (NR) - a Vitamin B3 Derivative - for Treatment of Mitochondrial Myopathy Disorder NCT05590468 NCT
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Received: February 28, 2026 Accepted: April 7, 2026 Published: May 5, 2026 Cite this article: Yang J, Chen S, Zeng T, Zhang Y, Li Z, Li H. The role of the resveratrol-sirtuin axis in the treatment o
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Nutrients. 2026 Mar 11;18(6):890. doi: 10.3390/nu18060890 # Effects of Nicotinamide Mononucleotide Supplementation on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Tri
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**Open Call for available White Space in the CECAD Research Center** **The CECAD Excellence Cluster on Aging and Aging-associated Diseases seeks independently funded research groups to join and suppor
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### Epigenetic clocks can accurately predict a person’s biological age. The processes behind this have now been specifically examined. 07/20/2026 · News · Leibniz-Institut für Alternsforschung - Fritz
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<table><tr><td> <table><tr><td>Title(s)</td><td>Professor of Gerontology and Biological Sciences, Edna M. Jones Chair in Gerontology</td></tr><tr><td>School</td><td>School of Gerontology</td></tr><tr>
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# San Antonio's Barshop Institute to test three approved drugs for slowing aging ... At UT Health San Antonio’s Sam and Ann Barshop Institute, researchers are preparing a major new test of an old scie
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NIA Intervention Testing Program (ITP) Announces Annual Call for Compounds to Test for Lifespan Extension in Mice Notice Number: NOT-AG-25-014 ## Key Dates Release Date: February 18, 2026 ## Related
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Newsroom | Max Planck Institute for Biology of Ageing ... ### Maxim Tobergte Receives Stefan Jentsch Award 2026 September 10, 2026 Achievement Career Institute Jachimowicz CGA alumnus recognized for e
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### The killifish reveals in fast-forward what takes decades in humans: chronic inflammation, DNA damage in precursor cells and remodelling processes in the blood-forming organ characterise the ageing
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06/22/2026 · News · Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut · Lebenswissenschaften · Forschungsergebnis A review article now published in “Nature Reviews Genetics” brings togeth
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The Interventions Testing Program (ITP) is a peer-reviewed program designed to identify agents that extend lifespan and healthspan in mice. Investigators at any university, institute, company, or othe
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The IHA is a centre of excellence for research on the biology of ageing and ageing related diseases. ... Upcoming Events 06 Nov in person Understanding evolution through game theory: Insights from stu
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### 15th AHA Conference ### 1st EFAR Conference ### Apply Now! New CECAD Postdoc Academy for Aging Trajectories! ... For PhD-Programme at the Cologne Graduate School of Ageing Research! ... #### Five-
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New policy notes from UCL IHE, Policy Impact Unit and CelebrAGE set out the challenges and opportunities of an ageing population. **Healthy Ageing Symposium: living better for longer** Bringing togeth
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A group of senior leaders from Flemish organisations working with older people (In4Care) visited the Aging Research Center (ARC) at Karolinska Institutet on 25 March 2026. The visit, hosted by the Tra
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Upcoming Lectures and Events ### Cologne Seminars on Ageing "Talk title to be confirmed" - Date: Dec 3, 2026 - Time: 01:00 PM - 02:00 PM (Local Time Germany) - Speaker: Ashley Webb (US) - Location: MP
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The mission of the European Institute for the Biology of Ageing (ERIBA) is to better understand what causes ageing.
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for a Ph.D. position at the Cologne Graduate School of Ageing Research! Deadline: November 03, 2026. ... We are one of the world's leading institutes for ageing research. Our mission is to understand
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Researchers have investigated the role played by the cell membrane lipid phosphatidylcholine in this process — and have identified a potential approach to healthy aging. 05/27/2026 · News · Leibniz-In
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The first EFAR conference will take place in Cologne, 14–16 October 2026, providing a platform for scientists across Europe to exchange knowledge and foster new partnerships in ageing research.
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“They’re all involved in one way or the other in the development of those diseases that are linked to aging,” says Elena Volpi, MD, PhD, director of the Sam and Ann Barshop Institute for Longevity and
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Scientists at the Max Planck Institute for the Biology of Ageing study how cells age during their lifetime and examine which genes and environmental factors are involved in the process. ... ### Contac
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ANTON, Feb 24 2026 /PRNewswire/ -- The University of Texas at San Antonio is establishing itself as a pivotal force in the realm of aging and longevity research, as Sam and Barshop for Long and Aging
### #69 - Dr. Valter Longo | Fasting, Longevity & Disease Prevention | Director of the USC Longevity InstituteJan 13 2026 Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they sp
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Published: 05-12-2025 18:39 | Updated: 20-04-2026 18:40 ... The Aging Research Center (ARC) celebrated its 25th anniversary on 1 December 2025, with an afternoon filled with reflections, presentations
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# Aging Research Center (ARC) A multidisciplinary research center, established in 2000 by Stockholm University and Karolinska Institutet, with the mission to improve the health and well-being of older
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Aging Research Center (ARC) offered an educational day focused on aging research | Karolinska Institutet Published: 26-02-2026 10:25 | Updated: 26-02-2026 10:25 ... When ARC turned 25 last year, they
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Aging Research Center (ARC) ‒ ett forskningscentrum för äldre personers hälsa och levnadsvillkor | Karolinska Institutet 1. / Neurobiologi, vårdvetenskap och samhälle 2. / Forskning ... # Aging Resear
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Age Innovation Hub will crowdsource ideas and needs for technologies to enable healthy ageing throughout the life-course. The needs and ideas identified will directly inform UCL research into healthy
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#### The National Institute for Health and Care Research (NIHR) Newcastle Biomedical Research Centre (BRC) brings together world-leading researchers and clinicians to turn early scientific breakthroug
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The Interventions Testing Program (ITP) tests potential agents that may delay aging as measured by lifespan extension and/or delayed onset/severity of late life pathologies. The ITP is funded by four
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**Anne Brunet, PhD** Director Paul F. Glenn Center for Biology of Aging Research at Stanford University Phone: (650) 725-8042 Email: abrunet1@stanford.edu Address: Stanford University School of Medici
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Symposium on Aging The 2026 Paul F. Glenn Center for the Biology of Aging Research BLAVATNIK INSTITUTE HARVARD MEDICAL SCHOOL The Paul F. Glenn Center for the Biology of Aging Research Each year the C
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CONFERENCE ON THE BIOLOGY OF AGING 39th Annual Glenn AFAR Grantee Conference Ritz-Carlton Bacara, Santa Barbara, California May 27 - 29, 2026 … The Paul F. Glenn/AFAR Conference on the Biology of A
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CECAD: 2026: 1st EFAR Conference on the Biology of Aging #### 1st Conference of the European Federation for Aging Research (EFAR) ... **When & Where: ** **Date: 14th - 16th October 2026** **Venue: MPI
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CECAD: 2026: 15th Alliance for Healthy Aging Conference ... **When & Where: ** **Date: 11th - 13th October 2026** **Venue: MPI for Biology of Ageing & CECAD Research Center, Cologne, Germany** ... Due
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#### Buck Institute Launches Healthspan Horizons to Turn Long-Term Health Data into Actionable Healthspan Insights A new healthspan research infrastructure linking real-world longitudinal data with de
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Phase 2 substudy in 20 older adults measures cardiac MRI effects of mTOR inhibition, University of Texas Health Science Center at San Antonio. Active, not recruiting. Primary completion October 2026.
Severe periodontitis and tooth loss were associated with roughly 1 to 2 extra years on several epigenetic clocks in 1,926 older adults.
In 232 adults with type 2 diabetes, oral semaglutide lowered HbA1c and weight over 24 months, but this was not a longevity trial.
A preprint reports an 8.5% median-lifespan increase in female mice, lower frailty in both sexes, and no lifespan increase in males after long-term NMN.
A mechanistic preprint connects HSP-1/HSPA8, translation control, lysosomal function and the trade-off between longevity and immunity.
Mature-donor hiPSC endothelial progenitors formed weaker vascular networks in vitro, with mitochondrial stress as a possible contributor.
In 97 aging male mice, caloric restriction produced regimen- and age-dependent liver apoptosis and anti-apoptotic changes rather than one uniform effect.
Resveratrol 500 mg/day for 180 days improved periodontal healing in 38 smokers; a dental commentary on a small 12-month trial.
In 57 youth with migraine, 12 weeks of omega-3 raised blood EPA and DHA but did not improve pain or disability scores.
Fish oil-derived fatty acids during pregnancy and risk of neurodevelopmental disorders in children at age 10 - A randomized controlled trial.
NEW VIDEO / N=1 EXPERIMENT: Johnson uploads “Can I dunk at 49?” and says he is training strength, speed and vertical jump; the video metadata reports no controlled outcome study.
NEW PROTOCOL CHANGE / CONTROVERSY: the current page exposes metformin 500 mg on 6-week on/off cycles and acarbose 200 mg in the daily Rx stack, while its separate Rx section still lists acarbose 400 m
*The Lancet Healthy Longevity* is a gold open-access, multi-disciplinary journal that publishes clinically-focussed longevity and healthy ageing research and review. The broad research remit aims to e
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Issues | The Journals of Gerontology: Series B | The Journals of Gerontology: Series B Volume 81, Issue Supplement_1, February 2026 Harmonization Recommendations from the Gateway to Global Aging Data
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Volume 81 Issue Supplement_1 | The Journals of Gerontology: Series B | Oxford Academic Volume 81, Issue Supplement_1 February 2026 Cover image EISSN 1758-5368 - Editorial ... - Research Articles ...
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# Nestlé-led clinical study finds that NAD+ boosters could promote health in unexpected ways - First-time evidence that 14-day supplementation of NR (nicotinamide riboside) and NMN (nicotinamide monon
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## Effects of Miricell Supplementation on Biomarkers of Healthy Aging and Autophagy ClinicalTrials.gov ID ** NCT07675200 Sponsor ** Nutraland USA, Inc. ... Last Update Posted ** 2026-06-30 **Recruitin
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*"Our findings suggest that the Cel System supplement range may effectively reduce biological age and improve health metrics, warranting further investigation into its mechanistic pathways and long-te
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A January 2026 trial in 65 adults showed NMN and NR raise NAD+ in the blood over 14 days. Plain nicotinamide did not. But the study measured a chemical, not your health. No trial has yet shown that a
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1,250mg Max tested NMN dose (safe) 0 Severe adverse events in trials A major review paper just dropped in *Nature Aging* (March 24, 2026). More than 25 scientists from the University of Oslo, Akershus
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Emerging 1 cite · 2026 NMN extends healthspan or lifespan in humans. *No outcome trial yet; biomarker engagement does not equal clinical benefit.* ... A 2024 systematic review of six randomized contro
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And new research suggests that part of the thinking that helped to fuel the booming market for these supplements may be wrong. A study published this month in Nature Metabolism showed that blood level
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A *Nature Metabolism* study confirmed that both NMN and NR double circulating NAD+ levels in 14 days. ... Key Takeaways - Life Biosciences received FDA IND clearance in 2026 to test ER-100, the first-
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Lifespan.io reviews top rejuvenation research advances including voice-based aging biomarkers and a rapamycin-exercise clinical trial. ... Lifespan.io's spring 2026 roundup highlights major momentum i
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A new 2026 *Cell Metabolism* study by Maura Fanti and colleagues gives the longevity-diet debate a more precise target than “eat less protein.” In aged mice, the group tested a low-amino-acid pattern
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### To Access GSA Journals 1. Log in at geron.org. 2. Click “**Journals**” in the top toolbar. 3. On the Journals page, select “**Access and Explore the GSA Journals**” to be taken to the OUP site (yo
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Download started.Ok ... #### Emulating target trials in older adults with multimorbidityPublished: July 28, 2025Older adults aged 75 years and older with multimorbidity remain severely under-represent
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A landmark 2026 longitudinal cohort study published in *Nature Metabolism* has provided the most robust clinical evidence to date that the age-related decline in **mitochondrial oxidative phosphorylat
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🚨 The February 2026 issue of eBioMedicine is now live! This month, we spotlight a question at the heart of modern medicine and longevity science: can we measure biological age in a way that truly impr
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September 10, 2026 · Baton Rouge, LA ### Published in Cell Metabolism, the paper suggests protein restriction triggers a coordinated whole-body response that may help explain its effects on healthy ag
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A 513-participant meta-analysis found NMN raises NAD+ with no serious adverse events up to 1,250 mg/day. ... The 2026 head-to-head trial led by Samuel Christen, PhD at Nestlé Research confirmed that N
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We’re excited to be attending the Longevity World Forum in Madrid (18–20 February) and connecting with researchers, clinicians, and innovators shaping the future of longevity science. ... 🚨 The Februa
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DUBAI, 5th February, 2026 (WAM) -- Ageing could soon be treated as a medical condition rather than an inevitable part of life, with scientists moving closer to reversing the biological clock, accordin
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A daily multivitamin–multimineral supplement significantly slowed certain markers of biological ageing after 2 years of treatment in a study involving 958 older adults. The results, published in *Natu
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Browse supplements Volume 81, Issue 7 July 2026 Cover image ... ##### Effects of a short-term multicomponent functional exercise program on the serum proteome: an exploratory study in hospitalized old
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## Aging appears to trigger a major biological transformation in the human brain beginning around midlife. ... September 15, 2026 ... Scientists have uncovered sweeping changes in how the human brain
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## Blocking one immune-cell receptor helped old mice stay leaner, stronger, sharper, and biologically younger across multiple organs. ... September 3, 2026 ... Aging may be partly fueled by immune cel
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## A large study of people over 90 is revealing that dementia risk does not simply fade away in extreme old age. ... September 1, 2026 ... A study of people over 90 found that dementia risk remains st
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July 9, 2026 ... Scientists found that a modified Mediterranean-style diet with low protein and just enough methionine helped mice live healthier lives while reducing body fat and frailty. Human data
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May 15, 2026 ... A casual conversation between graduate students helped spark a breakthrough in aging research at Mayo Clinic. Researchers discovered that tiny synthetic DNA molecules called aptamers
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## A 7-million-cell atlas reveals that aging is a synchronized, body-wide process that may finally be within reach of targeted therapies. - **Date:** February 28, 2026 - **Source:** ... Scientists hav
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For full access to this pdf, sign in to an existing account, or purchase an annual subscription.
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Stopping statins in adults 75 and older with no history of heart disease or stroke does not increase the risk of death over three years compared with continuing statins, although "bad" cholesterol ros
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The 2025 Nature Metabolism review on NAD+ precursors reaches a narrower conclusion than most longevity marketing: human evidence remains sparse, tissue responses are poorly characterized, and clinical
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##### Aug 21, 2026 (0:05:21) In this video, Dr. Rhonda Patrick covers: • What supplements make a good baseline for healthy aging? • Her magnesium supplement regimen • Is magnesium glycinate the best f
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In this video, Dr. Rhonda Patrick discusses: • Which five supplements make her non-negotiable list? ... So omega 3's are really at the top of the list mostly because most people {ts:20} don't want to
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Seeing the USP Verified Mark on a dietary supplement label indicates that the product: **Contains the ingredients listed on the label, in the declared potency and amounts**. Tests have shown that cont
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Real Mushrooms® Cordyceps Achieves NSF Certified for Sport® Status ... CALGARY, AB, Sept. 15, 2026 /PRNewswire/ -- Real Mushrooms®, a global leader in organic mushroom extracts, today announced that C
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USP is a nonprofit organization that sets official standards for medicines, supplements, and food ingredients used in the United States. The USP Verified mark indicates that a product has been tested
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This is why NSF developed the nation's first independent testing standard and product certification program strictly for dietary supplements. The program protects consumers by testing for harmful leve
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In this clip from a FoundMyFitness Premium Member Q&A episode, Rhonda updates listeners on her current supplement routine. Topics covered include: - Her preferred supplement brands & dosing - What tim
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# Q&A #79: Why I’m Taking Nicotinamide Riboside—Safety, Uncertainty, & Cycling Concerns Posted on March 31st 2026 (6 months) ... In this Q&A, Dr. Rhonda Patrick discusses nicotinamide riboside supplem
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NSF certifies dietary supplements to NSF/ANSI 173, the only American National Standard for testing and certifying dietary supplements. ... ## Certified for Sport® Our Certified for Sport program certi
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Published: November 2023 | Updated: May 2026 ... - Both NR and NMN have been shown to raise NAD+ levels and promote healthy aging. ... Nicotinamide riboside, or NR, is another precursor the body can u
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The second supplement is vitamin D3. ... The fourth supplement is magnesium.
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- A+ Healthy Joints System Glucosamine & Chondroitin Sulfate with MSM None
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Last updated on 21 Apr, 2026 Examine helps you understand what the research says about nutrition, supplements, and health — clearly and without bias from ads, sponsors, or partnerships.
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Published Jun 25, 2026 ... It’s not that we haven’t been slowly chipping away, keeping our pages up-to-date, and adding new content, but our small team has had our efforts focused on things like the S
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A-Z RANKING GRADE CERTIFIED FOR ... Gatorade Endurance Formula
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Reference #18.930a3d17.1743087055.4ca7c39
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This interactive database depicts the status of the most significant clinical trials of longevity-related therapies.
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NSF’s Certified for Sport® testing program helps confirm that sports supplements and sports nutritional products do not contain substances banned by many major athletic organizations. ... This indepen
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Last reviewed: March 31, 2026 | Next review: February 8, 2027 ... Only cGMP compliance under 21 CFR Part 111 is legally required for supplement manufacturers; every certification is voluntary. NSF/ANS
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A-Z RANKING GRADE CERTIFIED FOR ... Kirkland Signature Calcium + D3
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That’s why we sell more innovated supplements in more countries around the world than any other supplement brand. And it’s also why 98% of consumers recommend Solgar*. ... 3.3 ... (625) **31 reviews**
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- Common switching directions reported online / NR to NMN, NMN to NR, standalone NAD precursor to a "longevity stack," and cessation entirely - Typical self-reported timeline for noticing changes / 1
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(10) **3 reviews** in the last 12 months ... Great magnesium supplement in an easy-to-take liquid form. I've noticed improved relaxation and fewer muscle cramps since using it. The taste is pleasant,
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Discover the best protein powders for your fitness goals, backed by real Reddit user reviews. Our list covers top-ranked options like the creamy Wellah Grass-Fed Whey for the best overall quality, Nut
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## At a glance - Most common user-reported side effect / GI symptoms (nausea, bloating, loose stools), typically at doses above 500 mg - Second most common complaint / headaches in the first 1 to 2 we
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3.0 ... (31) **12 reviews** in the last 12 months
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## Contact info - Immermannstraße 45 , 40210, Düsseldorf, Germany ... 4.6 ## All reviews (4,988) **2,396 reviews** in the last 12 months ### Top mentions
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Looking at 30 reviews, reviewers overwhelmingly had a great experience with this company. Customers consistently praise the high quality and effectiveness of the daily supplements, noticing incredible
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**subreddit: /r/Supplements** author: Different_Week_96
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*13th Aging Research & Drug Discovery Meeting will convene leaders from pharma, biotechnology, academia, clinical medicine, investment, AI and policy October 1–3 at the David Rubenstein Treehouse at H
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Gerontological Society of America (GSA) welcomes your participation in the 2026 Annual Scientific Meeting in National Harbor, MD. Sessions and events will take place November 4-7. ... **Use GSA's offi
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Rooted in the One Health economy, our agenda was shaped as a progression, from diagnosing today’s systemic challenges to redesigning and scaling solutions across policy, science, markets, and culture,
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#### GSA 2026 in National Harbor, MD Join your colleagues at the premier Annual Scientific Meeting for fields related to gerontology. ... #### Free registration with booth purchase! Reserve your 2026
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## GSA 2026 Scientific Meeting November 4 - 7 | National Harbor, MD. Visit gsa2026.org ### Important Updates **Standard Registration—** September 2 - November 7—Register Now **Now Open— ** Register |
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The 13^th^ Aging Research & Drug Discovery (ARDD) Meeting, the world's largest conference dedicated to longevity biotechnology, will take place from October 1-3, 2026, at the David Rubenstein Treehous
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**04-21-2026** “*The 12th Aging Research and Drug Discovery (ARDD) meeting convened at the University of Copenhagen, presenting a comprehensive overview of recent advancements in the biology of aging*
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The 4th International Congress of the International Association of Biomedical Gerontology (IABG).
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1985 New York NY USA ... Promote biomedical *aging* studies directed towards increasing the functional life span of humans; keep the public informed of the progress of aging research and of practical
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This year we have an incredibly exciting program with global thought-leaders sharing their latest insights into aging and how we target aging process ensuring everyone lives a healthier and longer lif
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Urolithin A has a real randomized human trial base, which is more than most longevity supplements can claim. But both pivotal four-month trials missed their pre-specified primary endpoints, and the on
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Longevity Life Sciences and the University of Sydney have partnered on a major NMN clinical trial. ... In September 2026, NutraIngredients reported a major development in cellular health research. Lon
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# U of A Launches Rapamycin Clinical Trial with Philanthropic Support of Alumnus Ken Coit April 1, 2026 Researchers at the University of Arizona R. Ken Coit College of Pharmacy will begin a double-bli
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Human RCT evidence is thin: the SmartAge trial (PMID 35616942, N=100, 12 months) MISSED its primary cognitive endpoint. The earlier Wirth 2018 pilot (PMID 30388439, N=28) was positive but not replicat
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***From cellular recycling to cognitive aging, spermidine is drawing scientific interest, but the evidence needed for routine human use is still emerging.** * ... Review findings highlighted that whil
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### Age range 18 year–65 year ### Sex eligibility All sexes ### Study type Interventional ### Phase Not applicable ### Primary location ### Poznan University of Life Sciences Poznan, Wielkopolska, 60-
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Based on a randomized controlled trial of berberine (registered in ClinicalTrials.gov on Dec 2018, NCT03770325), leveraging proteomics and sex hormones data, we built a signature reflecting response t
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This systematic review evaluates the efficacy and safety of oral magnesium supplementation compared to placebo or standard care (sodium valproate) for migraine prophylaxis. ... We analyzed randomized,
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In a pre-specified ancillary study of the VITaminD and omegA-3 (VITAL) trial, we examined the effect of 1 g of marine omega-3 FA per day, comprised of 460 mg eicosapentanoic acid and 380 mg of docosah
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In preclinical models and laboratory model organisms, collagen supplementation increases the health and lifespan of rats 30, Drosophila 31, and C. elegans 32, 33, suggesting that collagen supplementat
NRPT is a combination of nicotinamide riboside (NR), a nicotinamide adenine dinucleotide (NAD +) precursor vitamin found in milk, and pterostilbene (PT), a polyphenol found in blueberries. Here, we re
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Article in Press Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials Nutrition Journal Rec
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This research marks the initial exploration into the safety of a new high-p spermid trihydroide supplement (hpSPD) for human use. ... In this randomized, double-blind, placebo-controlled trial, 37 hea
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# A Randomized Controlled Trial of Long-Term ( *R*)-α-Lipoic Acid Supplementation Promotes Weight Loss in Overweight or Obese Adults without Altering Baseline Elevated Plasma Triglyceride Concentratio
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## RBR-4cdm4k4 Study evaluating the effect of resveratrol on pain in women with lipedema Date of registration: 07/03/2026 ^(mm/dd/yyyy)^ Last approval date : 07/03/2026 ^(mm/dd/yyyy)^ ### Study type:
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## RBR-2g8tk6t Effects of resveratrol on heart health after exercise in menopausal women Date of registration: 04/22/2026 ^(mm/dd/yyyy)^ Last approval date : 04/22/2026 ^(mm/dd/yyyy)^ ### Study type:
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## RBR-2b7hw6b Impact of Resveratrol on the health of individuals with type 2 Diabetes Date of registration: 06/06/2026 ^(mm/dd/yyyy)^ Last approval date : 06/06/2026 ^(mm/dd/yyyy)^ ### Study type: In
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TYPE Systematic Review PUBLISHED 18 May 2026 DOI 10.3389/fnut.2026.1814168 OPEN ACCESS ... PUBLISHED 18 May 2026 CITATION Pan C, Wang S, Yang Y, Hu J and Pan Y (2026) Curcumin-piperine supplementati
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## Palvella Therapeutics Announces First Patients Dosed in Phase 2 LOTU Trial of Fast Track-Designated QTORIN™ Rapamycin for Clinically Significant Angiokeratomas May 4, 2026 ... *Phase 2 single-arm,
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We report results from the largest randomized, double-blind, placebo-controlled trial of nicotinamide mononucleotide (NMN) supplementation to date. Over 12 months, participants receiving 500 mg/day NM
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Last updated: June 24, 2026 Sponsor: Brigham and Women's Hospital Overall Status: Active - Recruiting #### Phase 2 #### Condition Renal Failure Kidney Failure Kidney Disease #### Treatment Placebo MIB
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The Effect of Aerobic Exercise on the Irisin/Klotho/Sirtuin-1/BDNF Axis (NCT07800156) | Clinical Trial Compass Not Yet RecruitingNot Applicable # The Effect of Aerobic Exercise on the Irisin/Klotho/Si
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Efficacy and Safety of Low-Dose Duloxetine Plus Alpha-Lipoic Acid Versus Standard-Dose Duloxetine… (NCT07785544) | Clinical Trial Compass Not Yet RecruitingNot Applicable # Efficacy and Safety of Low-
RecruitingNCT07760506Updated Sep 17, 2026 # The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health An interventional study of Quercetin (dietary supplement)
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Exercise and Taurine Supplementation on Intramuscular Fat in Older Women With Obesity (NCT07730255) | Clinical Trial Compass Active — Not RecruitingNot Applicable # Exercise and Taurine Supplementatio
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Effects of Creatine and Carbohydrate Supplementation on Endurance Performance (NCT07712653) | Clinical Trial Compass Not Yet RecruitingNot Applicable # Effects of Creatine and Carbohydrate Supplementa
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ClinicalTrials.gov ID ** NCT07703137 Sponsor ** University of Oklahoma ... Last Update Posted ** 2026-07-14 **Not yet recruiting** ** ... The goal of this clinical trial is to learn whether Nicotinami
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UCSD Chronic Kidney Disease Trial → Nicotinamide Riboside Supplementation in Chronic Kidney Disease ... ## Summary - **** Eligibility** **for people ages 30 years and up** (full criteria) - **** Locat
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## A Clinical Trial to Assess the Absorption, Safety, and Efficacy of an Oral Nicotinamide Adenine Dinucleotide (NAD+) Supplement in Healthy Adults ClinicalTrials.gov ID ** NCT07692633 Sponsor ** Reus
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## Assessment of the Effects and Safety of Spermidine Supplementation on Blood Lipids and Body Weight in Overweight or Obese Individuals With Hyperlipidemia ClinicalTrials.gov ID ** NCT07662330 Sponso
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Near-Infrared Spectroscopy, Acute Taurine Supplementation, and Isolated Muscular Endurance and Fa… (NCT07654946) | Clinical Trial Compass RecruitingNot Applicable # Near-Infrared Spectroscopy, Acute T
## Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients (ALA-MYO-PCOS) ClinicalTrials.gov ID ** NCT07630779 Sponsor ** Beni-Suef University Information provided by **
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RecruitingNCT07592767RESETUpdated Sep 18, 2026 # RESvEraTrol in Parkinson's Disease (RESET) A Phase 2 interventional study of Trans-Resveratrol in Parkinson's Disease, sponsored by Georgetown Universi
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Not yet recruiting** ## Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial) (ROSS) ClinicalTrials.gov ID ** NCT07579429 Sponsor ** University of Colorado, Denver Information provi
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## Mechanistic Study of Nicotinamide Riboside on NAD+ Biology in Individuals With Combined Pulmonary Hypertension ClinicalTrials.gov ID ** NCT07563322 Sponsor ** Vanderbilt University Medical Center I
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Completed** ## Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men (HIITCRECOG) ClinicalTrials.gov ID ** NCT07534293 Sponsor ** U
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Completed** ## Effect of Curcumin Add-On Therapy on Quality of Life and IL-1β Levels in Patients With Schizophrenia (CUR-SCZ) ClinicalTrials.gov ID ** NCT07523256 Sponsor ** Rinvil Renaldi ... Last Up
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Completed** ## Magnesium Supplementation With Fluoxetine for Cognitive Function in Depression (MAG-DEP) ClinicalTrials.gov ID ** NCT07521358 Sponsor ** Hasanuddin University ... Last Update Posted **
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## Short-Term Safety of Low-Dose Creatine Hydrochloride: A 28-Day Single-Arm Pilot Study ClinicalTrials.gov ID ** NCT07521059 Sponsor ** Vireo Systems, Inc. ... Last Update Posted ** 2026-04-09 **Comp
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## Effect of Magnesium Supplementation on Sleep Quality and Cognitive Function in Saudi Adults ClinicalTrials.gov ID ** NCT07515417 Sponsor ** Umm Al-Qura University ... Last Update Posted ** 2026-08-
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## Evaluation of the Hepatoprotective Effects of a Nutritional Supplement in Patients With Liver Disease Secondary to Chronic Hepatitis C Virus Infection (RESQUETI Study). (RESQUETI) ClinicalTrials.go
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Not yet recruiting** ## Can People Achieve a Target Omega-3 Index by Following a Personalized Omega-3 Dosing Regimen? ClinicalTrials.gov ID ** NCT07480707 Sponsor ** Fatty Acid Research Institute Info
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# Combination Gerotherapeutic Interventions for Healthspan Improvement **Status** Active, Not Recruiting **Phase** Phase 3 **Sponsor** AgelessRx **Started** 2025-07-23 View on ClinicalTrials.gov ↗ ...
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## Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat ClinicalTrials.gov ID ** NCT07472426 Sponsor ** University of Northern Iowa I
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## Study on the Efficacy of Quercetin Intake in Patients With Fibrotic Interstitial Lung Diseases. ClinicalTrials.gov ID ** NCT07466420 Sponsor ** Katerina M. Antoniou Information provided by ** Kater
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Not yet recruiting** ## Berberine Phytosome for Signs and Symptoms of Polycystic Ovary Syndrome (PCOS) ClinicalTrials.gov ID ** NCT07465575 Sponsor ** Liaquat University of Medical & Health Sciences .
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Not yet recruiting** ## Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease C
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RecruitingNCT07436130Updated Sep 17, 2026 # Curcumin in Critically Ill Patients With Sepsis An interventional study of Curcumin and Placebo in Sepsis, sponsored by Hospital Civil de Guadalajara. Recru
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# Effects of Lower Body Positive Pressure Therapy Versus Alpha Lipoic Acid and Omega-3 Fatty Acids on Knee Osteoarthritis **Status** Not Yet Recruiting **Phase** Phase 3 **Sponsor** Badr University **
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RecruitingNCT07383311SpSleepUpdated Jul 2, 2026 # Autophagy-Enhancers to Reduce Sleep Disturbances An interventional study of Spermidine Supplementation and Dietary Placebo in Mild Cognitive Impairmen
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## Evaluation of the Pharmacokinetics of Curcumin Capsules in Healthy HumanClinicalTrials.gov ID ## Study Overview Main objective: Through blood drug concentration testing, evaluate the post-meal phar
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## Influence of the Urolithin A on the Population With BMI Higher Than 30 During Restricted Eating. (Obesity UroA) ClinicalTrials.gov ID ** NCT07377136 Sponsor ** Charles University, Czech Republic In
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Fisetin in Mild Alzheimer's Disease (NCT07279714) | Clinical Trial Compass CompletedPhase 2 # Fisetin in Mild Alzheimer's Disease Canada5 participantsStarted 2026-01-27 ## Plain-language summary This
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# Sirtuin Activator Effects on Metabolism in Overweight Women Study Aim This study aims to observe the effects of a sirtuin activator on metabolism and ageing biomarkers, such as telomere length and b
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Clinical Trials/NCT07245979 NCT07245979RecruitingNot Applicable # Assessment of the Effect of Sirtuin Activator Supplementation on Cellular, Metabolic and Anthropometric Parameters in Women Poznan Uni
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## Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults ClinicalTrials.gov ID ** NCT07144527 Sponsor ** Scott Silveira ... Last Update Posted ** 2026-
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## Comparisons of NAD Precursors for Neuroenhancement in Glaucoma Patients ClinicalTrials.gov ID ** NCT06991712 Sponsor ** Christopher Kai Shun Leung ... Last Update Posted ** 2025-06-26 ... The goal
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## Creatine and Resistance Training in Older Adults With Mild Cognitive Impairment ClinicalTrials.gov ID ** NCT06948149 Sponsor ** Western University, Canada Information provided by ** Lindsay Nagamat
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## Intervention of Nicotinamide Mononucleotide in Middle-aged and Elderly People (NMNAGING) ClinicalTrials.gov ID ** NCT06592859 Sponsor ** People's Hospital of Quzhou Information provided by ** Feng
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## NAD+ Oral Supplement Pilot Intervention in Adult Females ClinicalTrials.gov ID ** NCT06579209 Sponsor ** University of Rhode Island Information provided by ** University of Rhode Island (Responsibl
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## Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With MultimorbidityClinicalTrials.gov ID ... We will conduct a clinical trial in healthy volunteers and older patients with multiple
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Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A… (NCT06274749) | Clinical Trial Compass RecruitingNot Applicable # Effects of Urolithin A Supplementat
## The NADage Study: Nicotinamide Riboside Replenishment Therapy Against Functional Decline in Aging (NADage)ClinicalTrials.gov ID ## Study Overview This clinical study, designed as a double-blind, ra
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## Fisetin to Improve Vascular Function in Older AdultsClinicalTrials.gov ID ## Study Overview Dietary Supplement: Fisetin Other: Placebo - 23-0288 ## Contacts and Locations ... To learn more, please
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## Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt (MIRACLE-ALA)ClinicalTrials.gov ID ## Study Overview This is a multicenter, interve
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Completed** ## Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression ClinicalTrials.gov ID ** NCT05774665 Sponsor ** Massachusetts General Hospital Information provided by ** Da
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Suspended # ABCD Berberine Treatment for Cardiometabolic Risk Reduction in High-Risk Individuals ... This study aims to evaluate the effectiveness of Berberine treatment in reducing the risk of new-on
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Recruiting NA INTERVENTIONAL 1-arm NCT05095571 # A Trial of Nicotinamide/Pterostilbene Supplement in ALS: The NO-ALS Extension Study A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbene
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Active Not Recruiting NA INTERVENTIONAL 2-arm NCT04562831 # The NO-ALS Study: A Trial of Nicotinamide/Pterostilbene Supplement in ALS. A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbe
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Suspended # The Study of Berberine Affecting Metabolism, Inflammation Status, Endothelial Function and Thrombotic Events in Patients With Coronary Artery Disease by Remodeling Gut Microbiota What is b
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**Verified**by 2020-01 Last known status was: Recruiting ## Basis: Evaluating Sirtuin Supplements To Benefit Elderly Trauma Patients (BES2T BET) (BestBet)ClinicalTrials.gov ID ## Study Overview Basis:
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## Metformin in Longevity Study (MILES). (MILES)ClinicalTrials.gov ID ## Study Overview ... In this proposal, the investigators explore the possibility of a commonly used drug, metformin, to reverse r
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Completed # Double-blind Cross-over Randomised Controlled Trial on the Anti-inflammatory and Antioxidant Effects of Resveratrol on Healthy Adults. ... ## Prevention Study Phase 3 Interventional Study
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## Vitamin D and Omega-3 Trial (VITAL) (VITAL) ClinicalTrials.gov ID ** NCT01169259 Sponsor ** Brigham and Women's Hospital ... Last Update Posted ** 2026-07-30 **Active, not recruiting** ** No longer
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There is now a first, encouraging randomized trial in heart-failure patients — and reading it carefully shows exactly why "promising" and "proven" are not the same word. ... ## The 2026 human trial: r
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The Targeting Aging with Metformin (TAME) trial, the first clinical trial to receive FDA approval targeting aging itself as an indication, reports interim results from its multi-center, randomized, pl
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# Metformin Shows Promise for Slowing Cellular Aging in Prediabetic Adults Six-month trial examines whether metformin treatment can improve telomere length and longevity gene expression in prediabetic
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Now, a new Indian study suggests the decades-old, inexpensive drug may be doing something far more than lowering blood sugar — it could be slowing down the biological clock inside human cells. The 24-
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713-798-4710 Houston, TX ... A randomized, double blind human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC – a combination of glycine
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A 2023 Baylor University trial found GlyNAC supplementation (glycine + N-acetylcysteine) reversed multiple aging hallmarks in healthy older adults. It's the most comprehensive clinical trial evidence
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Last reviewed: 2026-04-12Version 1Next review: approx. 12 monthsForm studied: Oral L-glycine at 3 g taken before bedtime for sleep outcomes; doses of 5–15 g/day studied for metabolic outcomes ... Thes
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Front. Neurol., 10 August 2026 ... Volume 17 - 2026 | https://doi.org/10.3389/fneur.2026.1904967 … The PubMed, Embase, Web of Science, Cochrane Library, and Scopus databases were systematically search
A two-year clinical study published June 18, 2026 directly tested whether they deliver on that promise, and the answer, by its own design the most rigorous test yet conducted, is no. The study specifi
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Received 14th April 2026 , Accepted 6th June 2026 First published on 15th June 2026 ## Abstract ... Taurine supplementation has shown promising outcomes in human studies, with emerging relevance in pr
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Last updated: July 12, 2026 Sponsor: Medinutra LLC Overall Status: Active - Recruiting #### Phase N/A #### Condition Inflammation #### Treatment Placebo Control Curcumin (Longvida™) Half Dose Curcumin
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|Unique ID issued by UMIN|UMIN000062041| ... |Receipt number|R000070989| |Scientific Title|Single-ingredient Vitamin D3 3200 IU versus Vitamin D3 3200 IU/Zinc/Quercetin Supplementation in Adult Indone
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Clinical Trials - ### FDA Greenlights Life Biosciences’ Human Study, Setting Up Pivotal Test for Aging Theory from Harvard’s David Sinclair Jan 30, 2026 - ### A Natural Senolytic Supplement Curbs Hear
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May 30, 2026 Nicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause transition: an open-label, pilot clinical trial. ... This study demonstrate
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Effects of Oral Taurine Supplementation on Cardiometabolic Risk Factors: A Meta-analysis and Systematic Review of Randomized Clinical Trials | Nutrition Reviews | Oxford Academic ... Volume 84 Issue
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# TauAge randomised, controlled pilot trial: Does taurine supplementation with 4 g/day for 6 months slow human ageing? Subject Area Biogerontology and Geriatric Medicine Term since 2026 Project identi
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Jeyakodi S et al. Int J Clin Trials. 2026 Aug;13(3):270-282 https://www.ijclinicaltrials.com ... Original Research Article Metaberine (bio-optimised berberine 200 mg/day) improves metabolic health mar
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Status: Enrolling # Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial Phase II Age ≥18 Sponsor National Cancer Institu
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Researchers are now exploring ways to boost NAD⁺ using compounds like NR and NMN, with early studies hinting at improvements in memory, metabolism, and physical function. ... The review examines years
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**Everolimus Aging Study (NCT05835999)** - **What’s being done:** low-dose everolimus to test whether mTORC1 inhibition can improve physiological and molecular hallmarks of aging. - **Population:** ol
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*Curr. Issues Mol. Biol.* **2026**, *48*(2), 216; https://doi.org/10.3390/cimb48020216 Submission received: 17 January 2026 / Revised: 13 February 2026 / Accepted: 15 February 2026 / Published: 16 Feb
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Reduced nicotinamide mononucleotide (NMNH) is a reduced NAD⁺ precursor with reported NAD⁺- augmenting activity in preclinical models; however, controlled human data remain limited. This was a randomiz
Healthy aging supplement shows limited benefits in older adults with cognitive impairment ... The results of a 12-week clinical trial, led by Christopher Martens, associate professor of kinesiology an
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This review evaluated randomized controlled trials of oral magnesium administered as a stand-alone intervention for sleep-related outcomes in adults. PubMed/MEDLINE, Scopus, Cochrane CENTRAL, Clinical
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Despite SRT1720 showing anti-cancer effects in vitro and in vivo, there are no human clinical trials reported to date. ... Thus, SRT2104 may be useful as a therapy to delay the development of diabetic
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**BUFFALO, NY — August 26, 2026 — ** A new review was published in Volume 18 of *Aging* on August 10, 2026, titled “Metformin at the convergence of aging and longevity.” ... However, the authors cauti
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Received: February 28, 2026 Accepted: April 7, 2026 Published: May 5, 2026 Cite this article: Yang J, Chen S, Zeng T, Zhang Y, Li Z, Li H. The role of the resveratrol-sirtuin axis in the treatment o
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. 2026 Jul 10;18(14):2251. doi: 10.3390/nu18142251. # Safety and Metabolism-Related Outcomes of Oral Nicotinamide Mononucleotide Supplementation in Adults: A Systematic Review and Meta-Analysis ... **
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##### Apr 02, 2026 Step into the world’s leading longevity lab as Dan Buettner sits down with Dr. Valter Longo, the pioneering Director of the Longevity Institute at USC, to uncover the "best medicine
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##### Jun 24, 2026 (1:00:59) ... Dr. Valter Longo, professor and director of the Longevity Institute at USC and one of the world’s leading researchers on aging, nutrition, and lifespan, joins Dr. Mich
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##### May 11, 2026 (1:48:36) ... Dr Valter Longo is Professor of Gerontology at USC and Director of the Longevity Institute. He developed the Fasting-Mimicking Diet, has led foundational work on the g
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**Valter D. Longo** (born 1967) is an Italian-American biogerontologist and cell biologist known for his studies on the role of fasting and nutrient response genes on cellular protection aging and dis
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# San Antonio's Barshop Institute to test three approved drugs for slowing aging ... At UT Health San Antonio’s Sam and Ann Barshop Institute, researchers are preparing a major new test of an old scie
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Our ongoing vision is to transform lives through world-leading research in ageing and multiple long-term conditions in the UK and beyond.
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NIA Intervention Testing Program (ITP) Announces Annual Call for Compounds to Test for Lifespan Extension in Mice Notice Number: NOT-AG-25-014 ## Key Dates Release Date: February 18, 2026 ## Related
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July 17, 2026 Video Our video explains the biological processes behind ageing more “In the end, it’s always about people” July 15, 2026 Career Institute PhD Coordinator Daniela Morick on trust, commun
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#### Two CGA Alumni Receive Klaus Liebrecht Award 17.06.2026 Label Research Group Leaders Label Doctoral Students Label 2026 Label University of Cologne Label CGA (Cologne Graduate School) Label Prof.
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longevity clinic ... Longevity Center | Europe provides a comprehensive approach to health through its advanced diagnostics and personalized longevity plans. Uniquely, it utilizes the Longevity Center
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Longevity Center is one of the leading longevity clinics worldwide, specializing in preventive, predictive, personalized medicine as well as biology and physiology of human aging. ... Make an appointm
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### The killifish reveals in fast-forward what takes decades in humans: chronic inflammation, DNA damage in precursor cells and remodelling processes in the blood-forming organ characterise the ageing
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06/22/2026 · News · Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut · Lebenswissenschaften · Forschungsergebnis A review article now published in “Nature Reviews Genetics” brings togeth
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The Interventions Testing Program (ITP) is a peer-reviewed program designed to identify agents that extend lifespan and healthspan in mice. Investigators at any university, institute, company, or othe
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The IHA is a centre of excellence for research on the biology of ageing and ageing related diseases. ... Upcoming Events 06 Nov in person Understanding evolution through game theory: Insights from stu
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### 15th AHA Conference ### 1st EFAR Conference ### Apply Now! New CECAD Postdoc Academy for Aging Trajectories! ... For PhD-Programme at the Cologne Graduate School of Ageing Research! ... #### The R
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New policy notes from UCL IHE, Policy Impact Unit and CelebrAGE set out the challenges and opportunities of an ageing population. **Healthy Ageing Symposium: living better for longer** Bringing togeth
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Home Events Public Events Scientific Events All Events Upcoming Lectures and Events Cologne Seminars on Ageing "Talk title to be confirmed" Date: Dec 3, 2026 Time: 01:00 PM - 02:00 PM (Local Time Germ
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We aim to elucidate the molecular, physiological and evolutionary mechanisms underlying ageing. ... ## Events ### #### Cologne Seminars on Ageing "Talk title to be confirmed" Dec 3, 2026 01:00 PM - 02
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Expert consensus identified 14 potential biomarkers of aging which may be used as outcome measures in intervention studies. ... moderate to high consensus (70%–98% agreement) on 14 biomarkers (IGF-1,
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Researchers have investigated the role played by the cell membrane lipid phosphatidylcholine in this process — and have identified a potential approach to healthy aging. 05/27/2026 · News · Leibniz-In
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The first EFAR conference will take place in Cologne, 14–16 October 2026, providing a platform for scientists across Europe to exchange knowledge and foster new partnerships in ageing research.
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Scientists at the Max Planck Institute for the Biology of Ageing study how cells age during their lifetime and examine which genes and environmental factors are involved in the process. ... ### Contac
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New research from University College London (UCL) has revealed a compelling connection between regular engagement with the arts and a slower pace of biological ageing. Led by Professor Daisy Fancourt
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Published: 05-12-2025 18:39 | Updated: 20-04-2026 18:40 ... The Aging Research Center (ARC) celebrated its 25th anniversary on 1 December 2025, with an afternoon filled with reflections, presentations
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A multidisciplinary research center, established in 2000 by Stockholm University and Karolinska Institutet, with the mission to improve the health and well-being of older individuals by contributing t
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# Aging Research Center (ARC) ‒ ett forskningscentrum för äldre personers hälsa och levnadsvillkor Ett multidisciplinärt forskningscentrum, inrättat år 2000 av Karolinska Institutet och Stockholms uni
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**Strategic collaboration between Hamburg and Groningen: In order to facilitate drug discovery and biomarker development within the theme Healthy Ageing, Fraunhofer IME ScreeningPort (Hamburg) and the
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Age Innovation Hub will crowdsource ideas and needs for technologies to enable healthy ageing throughout the life-course. The needs and ideas identified will directly inform UCL research into healthy
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The Interventions Testing Program (ITP) tests potential agents that may delay aging as measured by lifespan extension and/or delayed onset/severity of late life pathologies. The ITP is funded by four
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April 2, 2026 ... Researchers found that older adults carrying high-risk APOE gene variants didn’t show the expected cognitive decline if they ate relatively high amounts of meat. In fact, those with
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## A missing longevity protein may explain how aging brains turn a vital molecule toxic—and how that damage might be reversed. - **Date:** January 15, 2026 - **Source:** Ben-Gurion University of the N
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Symposium on Aging The 2026 Paul F. Glenn Center for the Biology of Aging Research BLAVATNIK INSTITUTE HARVARD MEDICAL SCHOOL The Paul F. Glenn Center for the Biology of Aging Research Each year the C
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CONFERENCE ON THE BIOLOGY OF AGING 39th Annual Glenn AFAR Grantee Conference Ritz-Carlton Bacara, Santa Barbara, California May 27 - 29, 2026 … The Paul F. Glenn/AFAR Conference on the Biology of A
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**When & Where: ** **Date: 14th - 16th October 2026** **Venue: MPI for Biology of Ageing & CECAD Research Center, Cologne, Germany** ... Please bring a printed version of your poster to the conference
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BEER-SHEVA, Israel, April 20, 2026 – New research from Ben-Gurion University of the Negev has found a critical role for the SIRT6 enzyme in preventing the formation of protein waste. SIRT6 is a natura
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Glycation Reduction and Aging, a Clinical Evaluation (GRACE) CLOSED Sugar-stress-lowering supplement for postmenopausal women #### GRACE STUDY ###### RECRUITING IS CLOSED Glycation stress is something
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*The Lancet Healthy Longevity* is a gold open-access, multi-disciplinary journal that publishes clinically-focussed longevity and healthy ageing research and review. The broad research remit aims to e
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Issues | The Journals of Gerontology: Series B | The Journals of Gerontology: Series B Volume 81, Issue Supplement_1, February 2026 Harmonization Recommendations from the Gateway to Global Aging Data
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Volume 81 Issue Supplement_1 | The Journals of Gerontology: Series B | Oxford Academic Volume 81, Issue Supplement_1 February 2026 Cover image EISSN 1758-5368 - Editorial ... - Research Articles ...
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The goal of our analysis was to test the hypothesis that vitamin D supplementation, omega-3 supplementation and a simple home exercise program (SHEP), individually and in combination, would slow biolo
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A January 2026 Nature Metabolism trial compared NMN, NR, and nicotinamide head-to-head in 65 adults. ... **In a randomized human trial reported in January 2026 in Nature Metabolism, researchers compar
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# Nestlé-led clinical study finds that NAD+ boosters could promote health in unexpected ways - First-time evidence that 14-day supplementation of NR (nicotinamide riboside) and NMN (nicotinamide monon
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## Effects of Miricell Supplementation on Biomarkers of Healthy Aging and Autophagy ClinicalTrials.gov ID ** NCT07675200 Sponsor ** Nutraland USA, Inc. ... Last Update Posted ** 2026-06-30 **Recruitin
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A January 2026 trial in 65 adults showed NMN and NR raise NAD+ in the blood over 14 days. Plain nicotinamide did not. But the study measured a chemical, not your health. No trial has yet shown that a
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בקליניקת עירויים אמריקאית אפשר לשכב על כורסת עור עד חמש שעות, לצפות בטיפה-טיפה של נוזל צהבהב נכנס לווריד, ולשלם על החוויה 599 דולר. ... בינואר 2026 פרסם צוות ממעבדת החדשנות הקלינית של נסטלה, שבסיסו בל
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And new research suggests that part of the thinking that helped to fuel the booming market for these supplements may be wrong. A study published this month in Nature Metabolism showed that blood level
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From creatine synergy with exercise to CRISPR cell-killing tools, May 2026 delivered a dense wave of longevity research advances. ... The May 2026 Rejuvenation Roundup from Lifespan.io covers a wide r
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A *Nature Metabolism* study confirmed that both NMN and NR double circulating NAD+ levels in 14 days. ... Key Takeaways ... - A January 2026 *Nature Metabolism* trial (65 adults, 14 days) found NMN an
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A new 2026 *Cell Metabolism* study by Maura Fanti and colleagues gives the longevity-diet debate a more precise target than “eat less protein.” In aged mice, the group tested a low-amino-acid pattern
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Volume 6, Issue 8 ... ISSN: 2666-7568
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Download started.Ok ... #### Emulating target trials in older adults with multimorbidityPublished: July 28, 2025Older adults aged 75 years and older with multimorbidity remain severely under-represent
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Fisetin, a flavonoid found in strawberries and apples, was identified as the most potent senolytic in a screen of 10 flavonoids. Phase I results from the Mayo Clinic show it is safe at high oral doses
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🚨 The February 2026 issue of eBioMedicine is now live! This month, we spotlight a question at the heart of modern medicine and longevity science: can we measure biological age in a way that truly impr
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DUBAI, 5th February, 2026 (WAM) -- Ageing could soon be treated as a medical condition rather than an inevitable part of life, with scientists moving closer to reversing the biological clock, accordin
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Aging is a multifactorial process influenced by genetic, environmental, and metabolic factors. Dysregulated nutrient sensing and metabolic dysfunction are hallmarks of aging, and reduction of insulin/
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A daily multivitamin–multimineral supplement significantly slowed certain markers of biological ageing after 2 years of treatment in a study involving 958 older adults. The results, published in *Natu
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Volume 81 Issue 9 | The Journals of Gerontology: Series B | Oxford Academic ... 202620252024202320222021202020192018201720162015201420132012201120102009200820072006200520042003200220012000199919981997
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Volume 81, Issue 5 May 2026 Cover image ... Joshua Stevenson-Hoare and others *The Journals of Gerontology: Series A*, Volume 81, Issue 5, May 2026, glag036, https://doi.org/10.1093/gerona/glag036 - -
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# Immune cells flood into the aging brain, Stanford scientists discover - **Date:** August 14, 2026 - **Source:** ... Scientists have discovered that the aging human brain may be far less isolated fro
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A naturally occurring compound found in foods such as wheat germ, mushrooms, and aged cheese may help older adults build stronger protection after vaccination. In a small pilot trial, researchers gave
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July 9, 2026 ... Scientists found that a modified Mediterranean-style diet with low protein and just enough methionine helped mice live healthier lives while reducing body fat and frailty. Human data
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## A 7-million-cell atlas reveals that aging is a synchronized, body-wide process that may finally be within reach of targeted therapies. ... February 28, 2026 ... Scientists have built a massive cell
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# Scientists uncover a hidden aging program in the gut that fuels cancer risk - **Date:** January 10, 2026 - **Source:** ... Although the gut renews itself constantly, its stem cells accumulate age-re
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A new perspective from LSU's Pennington Biomedical Research Center proposes a new way of understanding how dietary protein restriction may promote healthy aging and extend lifespan: through a coordina
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Volume 81 Issue 2 | The Journals of Gerontology: Series A | Oxford Academic Volume 81, Issue 2 February 2026 Cover image EISSN 1758-535X ... - Special Issue: Small Fish Models in Gerontology Research
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The mature way to read NMN and NR in 2026 is this: **both compounds can affect NAD-related biomarkers, both appear reasonably tolerable in studied settings, and neither has yet proved that it meaningf
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##### Apr 03, 2026 (0:09:00) Watch the full interview on the @hubermanlab podcast: https://www.youtube.com/watch?v=C0DMdUqF73Q In this clip, Dr. Rhonda Patrick discusses: • Multivitamins—essential nut
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##### Jun 17, 2026 (0:06:21) In this video from her appearance on Derek from More Plates More Dates' podcast, Dr. Rhonda Patrick discusses: • Her current supplement regimen • Why everyone taking a sta
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In this video, Dr. Rhonda Patrick discusses: • Which five supplements make her non-negotiable list? ... So omega 3's are really at the top of the list mostly because most people {ts:20} don't want to
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Reference #18.870f3417.1743024077.b6d06a8
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USP is a nonprofit organization that sets official standards for medicines, supplements, and food ingredients used in the United States. The USP Verified mark indicates that a product has been tested
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This is why NSF developed the nation's first independent testing standard and product certification program strictly for dietary supplements. The program protects consumers by testing for harmful leve
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In the US, dietary supplements are not reviewed by the FDA before sale, so third-party certifications exist to fill the verification gap. The three most rigorous consumer-facing marks are NSF Certifie
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In this member Q&A clip, Dr. Rhonda Patrick identifies five supplements she prioritizes when budget and simplicity matter: omega-3 fatty acids, vitamin D, a multivitamin, sulforaphane, and magnesium.
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In this clip from a FoundMyFitness Premium Member Q&A episode, Rhonda updates listeners on her current supplement routine. Topics covered include: - Her preferred supplement brands & dosing - What tim
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Labdoor ranks best-selling supplements by quality and value. See rankings for top multivitamins, protein, fish oil, energy drinks, and more.
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# TOP 10 PROTEIN #### See our 20 product reports.
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**ANN ARBOR, Mich.** – NSF, a global public health and safety organization, released its newly designed Certified for Sport® app and website to help protect athletes and consumers from potentially har
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Doctor-led NAD+ clinical trials in 2026 are listed on trusted sources including ClinicalTrials.gov, the NIH Clinical Research Trials portal, leading university medical centers, professional medical so
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- A+ Healthy Joints System Glucosamine & Chondroitin Sulfate with MSM None
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Last updated on 21 Apr, 2026 Examine helps you understand what the research says about nutrition, supplements, and health — clearly and without bias from ads, sponsors, or partnerships.
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Published Jun 25, 2026 ... It’s not that we haven’t been slowly chipping away, keeping our pages up-to-date, and adding new content, but our small team has had our efforts focused on things like the S
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Reference #18.930a3d17.1743087055.4ca7c39
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This interactive database depicts the status of the most significant clinical trials of longevity-related therapies.
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NSF’s Certified for Sport® testing program helps confirm that sports supplements and sports nutritional products do not contain substances banned by many major athletic organizations. ... This indepen
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A-Z RANKING GRADE CERTIFIED FOR ... Kirkland Signature Calcium + D3
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All seven hinge on purity and stability, not dose alone. ... **Brand comparison: YourHealthier, ProHealth (Uthever®), Alive By Science, Renue By Science, scored across key quality criteria** ... |Crit
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Independent test results, reviews, ratings, and comparisons of vitamins, supplements, herb and nutrition products to consumers and healthcare providers.
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Considering 1,654 reviews, reviewers overwhelmingly had a great experience with this company. Customers frequently praise the high quality of these daily supplements, noting significant improvements i
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Evaluating 48 reviews, reviewers overwhelmingly had a great experience with this company. ... **46 reviews** in the last 12 months
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94 • 4.7 Vitamin and Supplements Store ... Evaluating 61 reviews, reviewers overwhelmingly had a great experience with this company. Consumers frequently praise the exceptional product quality, reliab
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- Common switching directions reported online / NR to NMN, NMN to NR, standalone NAD precursor to a "longevity stack," and cessation entirely - Typical self-reported timeline for noticing changes / 1
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Discover the best protein powders for your fitness goals, backed by real Reddit user reviews. Our list covers top-ranked options like the creamy Wellah Grass-Fed Whey for the best overall quality, Nut
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**2 reviews** in the last 12 months ... I’ve been using the Soursop Liquid Drops daily for a few weeks and really like the formula. The liquid format is super convenient and easy to add to juice in th
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## At a glance - Most common user-reported side effect / GI symptoms (nausea, bloating, loose stools), typically at doses above 500 mg - Second most common complaint / headaches in the first 1 to 2 we
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Verification can help ensure real people are writing the reviews you read on Trustpilot.
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author: Different_Week_96 ... **votes: 3**
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*13th Aging Research & Drug Discovery Meeting will convene leaders from pharma, biotechnology, academia, clinical medicine, investment, AI and policy October 1–3 at the David Rubenstein Treehouse at H
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#### GSA 2026 in National Harbor, MD Join your colleagues at the premier Annual Scientific Meeting for fields related to gerontology. ... #### Free registration with booth purchase! Reserve your 2026
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**04-21-2026** “*The 12th Aging Research and Drug Discovery (ARDD) meeting convened at the University of Copenhagen, presenting a comprehensive overview of recent advancements in the biology of aging*
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## GSA 2026 Scientific Meeting November 4 - 7 | National Harbor, MD. Visit gsa2026.org ### Important Updates **Standard Registration—** September 2 - November 7—Register Now **Now Open— ** Register |
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The 4th International Congress of the International Association of Biomedical Gerontology (IABG).
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# 23rd IAGG world congress of gerontology and geriatrics , Amsterdam/NL On behalf of the executive committee of the 23rd IAGG World Congress of Gerontology and Geriatrics, we are pleased to invite you
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Gerontological Society of America • 2026 Annual Scientific Meeting Gerontological Society of America (GSA) 2026 Annual Scientific Meeting Reinforcing Resilience in Aging Science, Research, and Educ
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Insilico Medicine and Eli Lilly to Anchor 13th Aging Research & Drug Discovery (ARDD) Meeting at the David Rubenstein Treehouse at Harvard University Organized by Insilico Medicine, the world’s larges
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1985 New York NY USA ... Promote biomedical *aging* studies directed towards increasing the functional life span of humans; keep the public informed of the progress of aging research and of practical
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This year we have an incredibly exciting program with global thought-leaders sharing their latest insights into aging and how we target aging process ensuring everyone lives a healthier and longer lif
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11 PMIDs verified · Randomized human trials + independent meta-analysis · Evidence-graded Urolithin A has a real randomized human trial base, which is more than most longevity supplements can claim. B
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# U of A Launches Rapamycin Clinical Trial with Philanthropic Support of Alumnus Ken Coit April 1, 2026 Researchers at the University of Arizona R. Ken Coit College of Pharmacy will begin a double-bli
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Human RCT evidence is thin: the SmartAge trial (PMID 35616942, N=100, 12 months) MISSED its primary cognitive endpoint. The earlier Wirth 2018 pilot (PMID 30388439, N=28) was positive but not replicat
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***From cellular recycling to cognitive aging, spermidine is drawing scientific interest, but the evidence needed for routine human use is still emerging.** * ... Review findings highlighted that whil
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# Sirtuin Activators and Weight Loss Sponsor:Poznań University of Life SciencesAcademic & Hospital - **Status** Completed - **Phase** Not Applicable - **Sites** 11 country - **Enrollment** 45Actual -
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Dosing Completed in Phase 1 Trial of SRT501 to Treat Metabolic Disease CAMBRIDGE, Mass., June 7 /PRNewswire/ -- Sirtris Pharmaceuticals, the leading sirtuin therapeutics company, today announced that
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Based on a randomized controlled trial of berberine (registered in ClinicalTrials.gov on Dec 2018, NCT03770325), leveraging proteomics and sex hormones data, we built a signature reflecting response t
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In a pre-specified ancillary study of the VITaminD and omegA-3 (VITAL) trial, we examined the effect of 1 g of marine omega-3 FA per day, comprised of 460 mg eicosapentanoic acid and 380 mg of docosah
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In this study, we identify that simply the major amino acids of collagen in its proper ratio of 3 glycine : 1 proline : 1 hydroxyproline are sufficient to increase the lifespan of C. elegans and colla
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These cookies are necessary for the website to function and cannot be switched off in our systems.
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Dietary glycine increases healthy lifespan in model organisms and might decrease inflammation in humans, suggesting its geroprotective potential. This review summarises the evidence of glycine adminis
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This research marks the initial exploration into the safety of a new high-p spermid trihydroide supplement (hpSPD) for human use. ... In this randomized, double-blind, placebo-controlled trial, 37 hea
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## RBR-78bcfbc Effect of Curcumin on gut health and inflammatory aspects in Overweight and Obese individuals Date of registration: 07/08/2026 ^(mm/dd/yyyy)^ Last approval date : 07/08/2026 ^(mm/dd/yyy
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## RBR-4cdm4k4 Study evaluating the effect of resveratrol on pain in women with lipedema Date of registration: 07/03/2026 ^(mm/dd/yyyy)^ Last approval date : 07/03/2026 ^(mm/dd/yyyy)^ ### Study type:
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##### Public trial ## RBR-2g8tk6t Effects of resveratrol on heart health after exercise in menopausal women Date of registration: 04/22/2026 ^(mm/dd/yyyy)^ Last approval date : 04/22/2026 ^(mm/dd/yyyy
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## RBR-2b7hw6b Impact of Resveratrol on the health of individuals with type 2 Diabetes Date of registration: 06/06/2026 ^(mm/dd/yyyy)^ Last approval date : 06/06/2026 ^(mm/dd/yyyy)^ ### Study type: In
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Last updated: May 16, 2026 Sponsor: Ove Andersen Overall Status: Active - Recruiting #### Phase 1/2 #### Condition N/A #### Treatment Fisetin Placebo #### Clinical Study ID NCT06431932 Fisetin HIGH 20
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# Nicotinamide Riboside + Pterostilbene for Myelodysplastic Syndrome (ROSS Trial) ... This trial explores whether combining nicotinamide riboside and pterostilbene can improve low blood cell counts in
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## Palvella Therapeutics Announces First Patients Dosed in Phase 2 LOTU Trial of Fast Track-Designated QTORIN™ Rapamycin for Clinically Significant Angiokeratomas May 4, 2026 ... *Phase 2 single-arm,
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We report results from the largest randomized, double-blind, placebo-controlled trial of nicotinamide mononucleotide (NMN) supplementation to date. Over 12 months, participants receiving 500 mg/day NM
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Curcumin Versus Ibuprofen for Exercise-Induced Muscle Damage in Physically Active Women (NCT07785986) | Clinical Trial Compass CompletedNot Applicable # Curcumin Versus Ibuprofen for Exercise-Induced
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Efficacy and Safety of Low-Dose Duloxetine Plus Alpha-Lipoic Acid Versus Standard-Dose Duloxetine… (NCT07785544) | Clinical Trial Compass Not Yet RecruitingNot Applicable # Efficacy and Safety of Low-
## The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health ClinicalTrials.gov ID ** NCT07760506 Sponsor ** Applied Science & Performance Institute Information
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# N-AD: Orally Administered Nicotinamide Riboside Over Two Years as a Potential Disease Modifying Treatment for Alzheimer's Disease Study acronym: N-AD **Status** Recruiting **Phase** Phase 2 **Sponso
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Exercise and Taurine Supplementation on Intramuscular Fat in Older Women With Obesity (NCT07730255) | Clinical Trial Compass Active — Not RecruitingNot Applicable # Exercise and Taurine Supplementatio
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Effects of Creatine and Carbohydrate Supplementation on Endurance Performance (NCT07712653) | Clinical Trial Compass Not Yet RecruitingNot Applicable # Effects of Creatine and Carbohydrate Supplementa
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ClinicalTrials.gov ID ** NCT07703137 Sponsor ** University of Oklahoma Information provided by ** University of Oklahoma (Responsible Party) Last Update Posted ** 2026-07-14 **Not yet recruiting** **
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## A Clinical Trial to Assess the Absorption, Safety, and Efficacy of an Oral Nicotinamide Adenine Dinucleotide (NAD+) Supplement in Healthy Adults ClinicalTrials.gov ID ** NCT07692633 Sponsor ** Reus
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## Assessment of the Effects and Safety of Spermidine Supplementation on Blood Lipids and Body Weight in Overweight or Obese Individuals With Hyperlipidemia ClinicalTrials.gov ID ** NCT07662330 Sponso
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Near-Infrared Spectroscopy, Acute Taurine Supplementation, and Isolated Muscular Endurance and Fa… (NCT07654946) | Clinical Trial Compass RecruitingNot Applicable # Near-Infrared Spectroscopy, Acute T
## Nicotinamide Riboside, Vit B3 Analogue, and Brain Energy Metabolism ClinicalTrials.gov ID ** NCT07649161 Sponsor ** Massachusetts General Hospital Information provided by ** MOHAMED, SOLIMAN, Massa
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## Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients (ALA-MYO-PCOS) ClinicalTrials.gov ID ** NCT07630779 Sponsor ** Beni-Suef University Information provided by **
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Quercetin Dyskeratosis Congenita (DC)/Telomere Biology Disorders (TBD) (NCT07628972) | Clinical Trial Compass RecruitingPhase 1 # Quercetin Dyskeratosis Congenita (DC)/Telomere Biology Disorders (TBD)
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## Mechanistic Study of Nicotinamide Riboside on NAD+ Biology in Individuals With Combined Pulmonary Hypertension ClinicalTrials.gov ID ** NCT07563322 Sponsor ** Vanderbilt University Medical Center I
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Completed** ## Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men (HIITCRECOG) ClinicalTrials.gov ID ** NCT07534293 Sponsor ** U
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## Short-Term Safety of Low-Dose Creatine Hydrochloride: A 28-Day Single-Arm Pilot Study ClinicalTrials.gov ID ** NCT07521059 Sponsor ** Vireo Systems, Inc. ... (Responsible Party) Last Update Posted
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## Effect of Magnesium Supplementation on Sleep Quality and Cognitive Function in Saudi Adults ClinicalTrials.gov ID ** NCT07515417 Sponsor ** Umm Al-Qura University ... Last Update Posted ** 2026-08-
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Clinical Trial # Project SIRT6 Activator Recruiting Summary ... Fucoidan, a sulfated polysaccharide from brown macroalgae, is a safe dietary supplement with Sirtuin-6 (SIRT6) activating properties, wh
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## Evaluation of the Hepatoprotective Effects of a Nutritional Supplement in Patients With Liver Disease Secondary to Chronic Hepatitis C Virus Infection (RESQUETI Study). (RESQUETI) ClinicalTrials.go
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Not yet recruiting** ## Can People Achieve a Target Omega-3 Index by Following a Personalized Omega-3 Dosing Regimen? ClinicalTrials.gov ID ** NCT07480707 Sponsor ** Fatty Acid Research Institute Info
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Clinical Trials/NCT07475676 NCT07475676 Not Yet Recruiting N/A # Effects of Short-term Acute Creatine Supplementation on Power, Speed and Muscular Strengths in Young Football Players St. Mary's Univer
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# Combination Gerotherapeutic Interventions for Healthspan Improvement **Status** Active, Not Recruiting **Phase** Phase 3 **Sponsor** AgelessRx **Started** 2025-07-23 View on ClinicalTrials.gov ↗ ...
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## Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat ClinicalTrials.gov ID ** NCT07472426 Sponsor ** University of Northern Iowa I
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## Study on the Efficacy of Quercetin Intake in Patients With Fibrotic Interstitial Lung Diseases. ClinicalTrials.gov ID ** NCT07466420 Sponsor ** Katerina M. Antoniou Information provided by ** Kater
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Not yet recruiting** ## Berberine Phytosome for Signs and Symptoms of Polycystic Ovary Syndrome (PCOS) ClinicalTrials.gov ID ** NCT07465575 Sponsor ** Liaquat University of Medical & Health Sciences I
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Not yet recruiting** ## Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease C
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# Effects of Lower Body Positive Pressure Therapy Versus Alpha Lipoic Acid and Omega-3 Fatty Acids on Knee Osteoarthritis **Status** Not Yet Recruiting **Phase** Phase 3 **Sponsor** Badr University **
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## Evaluation of the Pharmacokinetics of Curcumin Capsules in Healthy HumanClinicalTrials.gov ID ## Study Overview Main objective: Through blood drug concentration testing, evaluate the post-meal phar
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## Influence of the Urolithin A on the Population With BMI Higher Than 30 During Restricted Eating. (Obesity UroA) ClinicalTrials.gov ID ** NCT07377136 Sponsor ** Charles University, Czech Republic In
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## Supplementation With Sirtuin Activators in Women With Increased Body WeightClinicalTrials.gov ID ## Study Overview The goal of this clinical trial is to learn if the six-month supplementation with
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## Fisetin Supplementation for Healthy Aging (Fisetin LOW)ClinicalTrials.gov ID ... The investigators will conduct a clinical trial in healthy volunteers, who will receive supplementation with fisetin
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## Magnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC) ClinicalTrials.gov ID ** NCT07149649 Sponsor ** Swiss Cancer Institute Information provided by ** Swiss Cancer Institute (Re
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## Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults ClinicalTrials.gov ID ** NCT07144527 Sponsor ** Scott Silveira ... Last Update Posted ** 2026-
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Recruiting soon # Omega-3 Fatty Acid Supplementation for Adult and Juvenile Dermatomyositis What is being tested ## FISH OIL 500MG OMEGA-3 SOFT GEL MINIS + Placebo Dietary Supplement Who is being recr
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## Sequential Treatments or Combinations Including Dasatinib, Quercetin, Fisetin and/or Temozolomide for the Treatment of Previously Treated Glioma With Residual Disease (Senolytics) ClinicalTrials.g
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## Comparisons of NAD Precursors for Neuroenhancement in Glaucoma Patients ClinicalTrials.gov ID ** NCT06991712 Sponsor ** Christopher Kai Shun Leung ... The goal of this clinical trial is to determin
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## Creatine and Resistance Training in Older Adults With Mild Cognitive Impairment ClinicalTrials.gov ID ** NCT06948149 Sponsor ** Western University, Canada ... Last Update Posted ** 2026-05-19 **Rec
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## Intervention of Nicotinamide Mononucleotide in Middle-aged and Elderly People (NMNAGING) ClinicalTrials.gov ID ** NCT06592859 Sponsor ** People's Hospital of Quzhou Information provided by ** Feng
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## NAD+ Oral Supplement Pilot Intervention in Adult Females ClinicalTrials.gov ID ** NCT06579209 Sponsor ** University of Rhode Island Information provided by ** University of Rhode Island (Responsibl
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# Urolithin A Supplement for Glucose Metabolism in Adults 55+ ... This study aims to determine if taking Urolithin A as a supplement can affect how your body secretes insulin after consuming glucose,
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## The NADage Study: Nicotinamide Riboside Replenishment Therapy Against Functional Decline in Aging (NADage)ClinicalTrials.gov ID ## Study Overview This clinical study, designed as a double-blind, ra
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## Fisetin to Improve Vascular Function in Older AdultsClinicalTrials.gov ID ## Study Overview Dietary Supplement: Fisetin Other: Placebo - 23-0288 ## Contacts and Locations ... To learn more, please
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## Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative NeoplasmsClinicalTrials.gov I
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## Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt (MIRACLE-ALA)ClinicalTrials.gov ID ## Study Overview This is a multicenter, interve
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Completed** ## Specialized Pro-resolving Lipid Mediators and Treatment Resistant Depression ClinicalTrials.gov ID ** NCT05774665 Sponsor ** Massachusetts General Hospital Information provided by ** Da
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Suspended # ABCD Berberine Treatment for Cardiometabolic Risk Reduction in High-Risk Individuals Study Aim This study aims to evaluate the effectiveness of Berberine treatment in reducing the risk of
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Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity (NCT05713799) | Clinical Trial Compass Not Yet RecruitingPhase 2 # Trial of the Combination of Alpha-Lipoi
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Active, not recruiting** ## Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure ClinicalTrials.gov ID ** NCT05690464 Sponsor ** Brigham and Women's Hospital ... The purpose of this
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Active Not Recruiting NA INTERVENTIONAL 2-arm NCT04562831 # The NO-ALS Study: A Trial of Nicotinamide/Pterostilbene Supplement in ALS. A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbe
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## Vitamin D and Omega-3 Trial (VITAL) (VITAL) ClinicalTrials.gov ID ** NCT01169259 Sponsor ** Brigham and Women's Hospital ... Last Update Posted ** 2026-07-30 **Active, not recruiting** ** No longer
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Dietary Supplement: Resveratrol Other: Placebo - M-20100058 ## Contacts and Locations ... To learn more, please see the **Aarhus, Denmark, 8000** ... Inclusion Criteria: - BMI > 30 kg/m2 - Otherwise h
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There is now a first, encouraging randomized trial in heart-failure patients — and reading it carefully shows exactly why "promising" and "proven" are not the same word. ... ## The 2026 human trial: r
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The Targeting Aging with Metformin (TAME) trial, the first clinical trial to receive FDA approval targeting aging itself as an indication, reports interim results from its multi-center, randomized, pl
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# Metformin Shows Promise for Slowing Cellular Aging in Prediabetic Adults Six-month trial examines whether metformin treatment can improve telomere length and longevity gene expression in prediabetic
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Now, a new Indian study suggests the decades-old, inexpensive drug may be doing something far more than lowering blood sugar — it could be slowing down the biological clock inside human cells. The 24-
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**Metformin is FDA-approved only for type 2 diabetes; it is not approved for aging, and no aging indication is under FDA review. As of September 5, 2026, the anti-aging case rests on animal data (male
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# Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19 ## ID#: NCT06960928 ## Age: 18 years - 66+ ## Gender: All ## Healthy Subjects: No ## Study Phase: Phase 3 ## Re
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|最近我々は、マウスを用いた動物試験により、レスベラトロール類の一つであるプテロスチルベンが、高齢卵子で減少している抗老化遺伝子SIRTの発現を増加させ、エイジングにより低下したミトコンドリア機能を向上させ、その結果妊娠率が改善することを見出した（特願：2016-187572, PCT/JP2017/34361）。そこで本研究では、動物試験においてエイジング卵子の質の改善に対する有用性を確認したサ
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This study aims to assess whether a 6-month oral taurine supplementation program improves blood glucose control and other health parameters among healthcare workers. ... This study is a Bayesian-optim
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# Exercise and Weekly Sirolimus (Rapamycin) in Older Adults: RAPA-EX-01 Randomised, Double-Blind, Placebo-Controlled Trial Brad Stanfield, ... First published: 15 April 2026 https://doi.org/10.1002/jc
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713-798-4710 ... A randomized, double blind human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC – a combination of glycine and N-acetyl
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A 2023 Baylor University trial found GlyNAC supplementation (glycine + N-acetylcysteine) reversed multiple aging hallmarks in healthy older adults. It's the most comprehensive clinical trial evidence
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Last reviewed: 2026-04-12Version 1Next review: approx. 12 monthsForm studied: Oral L-glycine at 3 g taken before bedtime for sleep outcomes; doses of 5–15 g/day studied for metabolic outcomes ... Thes
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Front. Nutr., 22 July 2026 Sec. Nutrition and Metabolism Volume 13 - 2026 | https://doi.org/10.3389/fnut.2026.1834344 … ... Urolithin A (UA), a gut microbiota–derived metabolite, has been proposed to
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Received 14th April 2026 , Accepted 6th June 2026 First published on 15th June 2026 ## Abstract ... Taurine supplementation has shown promising outcomes in human studies, with emerging relevance in pr
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|Unique ID issued by UMIN|UMIN000062041| ... |Receipt number|R000070989| |Scientific Title|Single-ingredient Vitamin D3 3200 IU versus Vitamin D3 3200 IU/Zinc/Quercetin Supplementation in Adult Indone
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# Assessing the Safety and Tolerability of NMN in DHDDS-CDG ## ID#: NCT07572825 ## Age: 4 years - 66+ ## Gender: All ## Healthy Subjects: No ## Study Phase: Phase 1 ## Recruitment Status: Recruiting #
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# Spermidine Mitigates Immune Cell Senescence and Boosts Vaccine Responses in Healthy Older Adults—A Pilot Study Ghada Alsaleh, ... **Correspondence:** Ghada Alsaleh ([email protected]) Lucy C. Jones
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SHELTON, Conn., Feb. 02, 2026 (GLOBE NEWSWIRE) -- **Abinopharm, Inc.**, a U.S.-based life-science company headquartered in Shelton, Connecticut, today announced the publication of its newly released *
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May 30, 2026 Nicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause transition: an open-label, pilot clinical trial. ... This study demonstrate
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# The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial ``` @article{Lopresti2026TheEO, title={The
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Effects of Oral Taurine Supplementation on Cardiometabolic Risk Factors: A Meta-analysis and Systematic Review of Randomized Clinical Trials | Nutrition Reviews | Oxford Academic ... Volume 84 Issue
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Project Details # TauAge randomised, controlled pilot trial: Does taurine supplementation with 4 g/day for 6 months slow human ageing? Subject Area Biogerontology and Geriatric Medicine Term since 202
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Jeyakodi S et al. Int J Clin Trials. 2026 Aug;13(3):270-282 ... Original Research Article Metaberine (bio-optimised berberine 200 mg/day) improves metabolic health markers in healthy adults: a rando
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Status: Enrolling # Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial Phase II Age ≥18 Sponsor National Cancer Institu
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Status: Enrolling # Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms Ph
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To evaluate the efficacy and safety of berberine in reducing VAT area and liver fat content in diabetes-free individuals with obesity and metabolic dysfunction-associated steatotic liver disease (MASL
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# Curcumin Supplementation Reduces Inflammation, Neutrophil-to-Lymphocyte Ratio (NLR), and Antioxidant Status in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial by Metha Yaikwawong
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Orr · GeroScience 2024 · randomized placebo-controlled trial · n=20 # A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment. ... Level 2 - rando
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Dellinger · Hepatology (Baltimore, Md.) 2023 · randomized, double-blind, placebo-controlled trial · n=111 # Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A
British Journal of Nutrition Accepted manuscript # Impact of creatine monohydrate supplementation combined with multicomponent training in older adults (≥75 years): study protocol of a randomized cont
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*Curr. Issues Mol. Biol.* **2026**, *48*(2), 216; https://doi.org/10.3390/cimb48020216 Submission received: 17 January 2026 / Revised: 13 February 2026 / Accepted: 15 February 2026 / Published: 16 Feb
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Reduced nicotinamide mononucleotide (NMNH) is a reduced NAD⁺ precursor with reported NAD⁺- augmenting activity in preclinical models; however, controlled human data remain limited. This was a randomiz
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Randomized Controlled Trial ... . 2026 Dec 31;23(1):2632284. doi: 10.1080/15502783.2026.2632284. Epub 2026 Feb 18. # Anti-inflammatory effects of nicotinamide mononucleotide (NMN) in human skeletal mu
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**Valter D. Longo** (born 1967) is an Italian-American biogerontologist and cell biologist known for his studies on the role of fasting and nutrient response genes on cellular protection aging and dis
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The Sam and Ann Barshop Institute for Longevity and Aging Studies at UT Health San Antonio, the academic health center of The University of Texas at San Antonio (UT San Antonio) will receive up to $38
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- A study published in Nature Communications by researchers at Germany’s Leibniz Institute on Aging identifies falling levels of phosphatidylcholine (PC) as a driver of mitochondrial aging. ... An Apr
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# San Antonio's Barshop Institute to test three approved drugs for slowing aging ... At UT Health San Antonio’s Sam and Ann Barshop Institute, researchers are preparing a major new test of an old scie
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The Hunter New England Central Coast Primary Health Network (HNECC PHN) and the I2N at the University of Newcastle have successfully concluded their pioneering "Healthy Ageing Innovation Challenge," a
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A major emphasis of work at the Institute of Healthy Ageing is identifying the genes that control senescence and analysing how they work, as a route to understand ageing itself. ... Our vision is to d
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NIA Intervention Testing Program (ITP) Announces Annual Call for Compounds to Test for Lifespan Extension in Mice Notice Number: NOT-AG-25-014 ## Key Dates Release Date: February 18, 2026 ## Related
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July 17, 2026 Video Our video explains the biological processes behind ageing more “In the end, it’s always about people” July 15, 2026 Career Institute PhD Coordinator Daniela Morick on trust, commun
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Longevity Center is one of the leading longevity clinics worldwide, specializing in preventive, predictive, personalized medicine as well as biology and physiology of human aging. ... Make an appointm
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Warsaw, Masovian Voivodeship, Poland ### About ... ### Contacts **Website:** https://linktr.ee/longevity_center ### Locations - Golfplatz, 1, Donaueschingen, Baden-Württemberg 78166, DE, Donaueschinge
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#### Epigenetic clocks can accurately predict a person’s biological age. The processes behind this have now been specifically examined. ... #### As we get older, we lose energy and resilience. Researc
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06/22/2026 · News · Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut · Lebenswissenschaften · Forschungsergebnis A review article now published in “Nature Reviews Genetics” brings togeth
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The Interventions Testing Program (ITP) is a peer-reviewed program designed to identify agents that extend lifespan and healthspan in mice. Investigators at any university, institute, company, or othe
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The IHA is a centre of excellence for research on the biology of ageing and ageing related diseases. ... Upcoming Events 06 Nov in person Understanding evolution through game theory: Insights from stu
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### 15th AHA Conference ### 1st EFAR Conference ### Apply Now! New CECAD Postdoc Academy for Aging Trajectories! ### Apply Now! For PhD-Programme at the Cologne Graduate School of Ageing Research! ...
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The idea of a research centre for fundamental biogerontological research arose from a desire to integrate insights from model organisms. ... The idea of an Institute of Healthy Ageing was based on a m
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New policy notes from UCL IHE, Policy Impact Unit and CelebrAGE set out the challenges and opportunities of an ageing population. **Healthy Ageing Symposium: living better for longer** Bringing togeth
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Published: 26-03-2026 10:27 | Updated: 26-03-2026 10:57 ... A group of senior leaders from Flemish organisations working with older people (In4Care) visited the Aging Research Center (ARC) at Karolins
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Home Events Public Events Scientific Events All Events Upcoming Lectures and Events Cologne Seminars on Ageing "Molecular functions of the nuclear lamina in cell aging & senescence" Date: Sep 14, 2026
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We aim to elucidate the molecular, physiological and evolutionary mechanisms underlying ageing. ... ## Events ### #### Cologne Seminars on Ageing "Molecular functions of the nuclear lamina in cell agi
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Expert consensus identified 14 potential biomarkers of aging which may be used as outcome measures in intervention studies.
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Researchers have investigated the role played by the cell membrane lipid phosphatidylcholine in this process — and have identified a potential approach to healthy aging. 05/27/2026 · News · Leibniz-In
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The European Research Institute for the Biology of Ageing (ERIBA), part of the UMCG and the University of Groningen, has partnered with leading centres across Europe to launch the European Federation
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## Contact and visit us ### Postal address Aging Research Center, Department of Neurobiology, Care Sciences and Society Karolinska Institutet SE-171 77 Stockholm ### Visiting address Tomtebodavägen 18
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Scientists at the Max Planck Institute for the Biology of Ageing study how cells age during their lifetime and examine which genes and environmental factors are involved in the process. ... ### Contac
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### #69 - Dr. Valter Longo | Fasting, Longevity & Disease Prevention | Director of the USC Longevity InstituteJan 13 2026 Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they sp
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Published: 05-12-2025 18:39 | Updated: 20-04-2026 18:40 ... The Aging Research Center (ARC) celebrated its 25th anniversary on 1 December 2025, with an afternoon filled with reflections, presentations
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A multidisciplinary research center, established in 2000 by Stockholm University and Karolinska Institutet, with the mission to improve the health and well-being of older individuals by contributing t
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The Interventions Testing Program (ITP) tests potential agents that may delay aging as measured by lifespan extension and/or delayed onset/severity of late life pathologies. The ITP is funded by four
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## A missing longevity protein may explain how aging brains turn a vital molecule toxic—and how that damage might be reversed. - **Date:** January 15, 2026 - **Source:** Ben-Gurion University of the N
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Symposium on Aging The 2026 Paul F. Glenn Center for the Biology of Aging Research BLAVATNIK INSTITUTE HARVARD MEDICAL SCHOOL The Paul F. Glenn Center for the Biology of Aging Research Each year the C
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CONFERENCE ON THE BIOLOGY OF AGING 39th Annual Glenn AFAR Grantee Conference Ritz-Carlton Bacara, Santa Barbara, California May 27 - 29, 2026 … The Paul F. Glenn/AFAR Conference on the Biology of A
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**When & Where: ** **Date: 14th - 16th October 2026** **Venue: MPI for Biology of Ageing & CECAD Research Center, Cologne, Germany** ... Please bring a printed version of your poster to the conference
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Each year, a conference is organized for scientists, clinicians, engineers, and students to exchange research results and ideas on translational research on aging. ... **When & Where: ** **Date: 11th
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BEER-SHEVA, Israel, April 20, 2026 – New research from Ben-Gurion University of the Negev has found a critical role for the SIRT6 enzyme in preventing the formation of protein waste. SIRT6 is a natura
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Glycation Reduction and Aging, a Clinical Evaluation (GRACE) CLOSED Sugar-stress-lowering supplement for postmenopausal women #### GRACE STUDY ###### RECRUITING IS CLOSED Glycation stress is something
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Volume 81 Issue Supplement_1 | The Journals of Gerontology: Series B | Oxford Academic Volume 81, Issue Supplement_1 February 2026 Cover image EISSN 1758-5368 - Editorial ... # Volume 81, Issue Suppl
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This prespecified ancillary study evaluated the 2-year effect of a daily MVM (Centrum Silver) and cocoa extract (500 mg cocoa flavanols per day, including 80 mg (−)-epicatechin) on five DNA methylatio
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- Rigorous new human research found whole-blood NAD+ levels don't decline with age, challenging the core premise behind NAD+ supplements, including NMN. - The clinical evidence that NMN and other NAD+
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## Effects of Miricell Supplementation on Biomarkers of Healthy Aging and Autophagy ClinicalTrials.gov ID ** NCT07675200 Sponsor ** Nutraland USA, Inc. ... Last Update Posted ** 2026-06-30 **Recruitin
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A new 2026 *Cell Metabolism* study by Maura Fanti and colleagues gives the longevity-diet debate a more precise target than “eat less protein.” In aged mice, the group tested a low-amino-acid pattern
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### To Access GSA Journals 1. Log in at geron.org. 2. Click “**Journals**” in the top toolbar. 3. On the Journals page, select “**Access and Explore the GSA Journals**” to be taken to the OUP site (yo
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Download started.Ok ... #### Emulating target trials in older adults with multimorbidityPublished: July 28, 2025Older adults aged 75 years and older with multimorbidity remain severely under-represent
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A landmark 2026 longitudinal cohort study published in *Nature Metabolism* has provided the most robust clinical evidence to date that the age-related decline in **mitochondrial oxidative phosphorylat
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**BUFFALO, NY — April 21, 2026 — ** A new meeting report was published in Volume 18 of *Aging-US* on April 6, 2026, titled “Toward actionable interventions in human aging (12th ARDD meeting, 2025).”
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Improved blood-based DNA tests indicate that these interventions seem to be the most effective at slowing the biological aging process: • Prescribed medications for metabolic control and weight manage
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DUBAI, 5th February, 2026 (WAM) -- Ageing could soon be treated as a medical condition rather than an inevitable part of life, with scientists moving closer to reversing the biological clock, accordin
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A daily multivitamin–multimineral supplement significantly slowed certain markers of biological ageing after 2 years of treatment in a study involving 958 older adults. The results, published in *Natu
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Volume 81 Issue 9 | The Journals of Gerontology: Series A | Oxford Academic Volume 81, Issue 9 September 2026 (In Progress) ... # Volume 81, Issue 9, September 2026 ... ##### Leisure-time physical ac
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Browse supplements Volume 81, Issue 7 July 2026 Cover image ... Maite Izco-Cubero and others *The Journals of Gerontology: Series A*, Volume 81, Issue 7, July 2026, glag111, https://doi.org/10.1093/ge
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Volume 81, Issue 5 May 2026 Cover image ... Joshua Stevenson-Hoare and others *The Journals of Gerontology: Series A*, Volume 81, Issue 5, May 2026, glag036, https://doi.org/10.1093/gerona/glag036 - .
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Showing papers in "The Lancet Healthy Longevity in 2026" Journal Article 10.1016/j.lanhl.2026.100818 Thank you to The Lancet Healthy Longevity statistical and peer reviewers in 2025. ... The Lancet He
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Reference #18.870f3417.1743024077.b6d06a8
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USP is a nonprofit organization that sets official standards for medicines, supplements, and food ingredients used in the United States. The USP Verified mark indicates that a product has been tested
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Dr. Rhonda Patrick walks through her October 2024 supplement routine, including omega-3s, creatine, magnesium, collagen, and zinc lozenges.
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This is why NSF developed the nation's first independent testing standard and product certification program strictly for dietary supplements. The program protects consumers by testing for harmful leve
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### Certified Products Results Your search for **all products** returned the results below.
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In this clip from a FoundMyFitness Premium Member Q&A episode, Rhonda updates listeners on her current supplement routine. Topics covered include: - Her preferred supplement brands & dosing - What tim
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Last updated on 21 Apr, 2026 Examine helps you understand what the research says about nutrition, supplements, and health — clearly and without bias from ads, sponsors, or partnerships.
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Reference #18.930a3d17.1743087055.4ca7c39
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This interactive database depicts the status of the most significant clinical trials of longevity-related therapies.
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NSF’s Certified for Sport® testing program helps confirm that sports supplements and sports nutritional products do not contain substances banned by many major athletic organizations. ... This indepen
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Dr. Rhonda Patrick reviews omega-3, multivitamins, vitamin D, magnesium, and creatine for nutrient gaps, exercise, and brain energy.
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*13th Aging Research & Drug Discovery Meeting will convene leaders from pharma, biotechnology, academia, clinical medicine, investment, AI and policy October 1–3 at the David Rubenstein Treehouse at H
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#### GSA 2026 in National Harbor, MD Join your colleagues at the premier Annual Scientific Meeting for fields related to gerontology. ... #### Free registration with booth purchase! Reserve your 2026
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## GSA 2026 Scientific Meeting November 4 - 7 | National Harbor, MD. Visit gsa2026.org ### Important Updates **Late Breaking Abstracts**—Now Open | July 7 - August 13 **Now Open— ** Register | Book Yo
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## GSA 2026 Scientific Meeting November 4 - 7 | National Harbor, MD. Visit gsa2026.org ### Important Updates **Early Bird Registration—** Closes September 1, 11:59 PM ET **Now Open—
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The 4th International Congress of the International Association of Biomedical Gerontology (IABG).
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Insilico Medicine and Eli Lilly to Anchor 13th Aging Research & Drug Discovery (ARDD) Meeting at the David Rubenstein Treehouse at Harvard University Organized by Insilico Medicine, the world’s larges
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1985 New York NY USA ... Promote biomedical *aging* studies directed towards increasing the functional life span of humans; keep the public informed of the progress of aging research and of practical
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3 min read Last Updated : Aug 17 2026 | 5:00 PM IST Hyderabad (Telangana) [India], August 17: Zeus Hygia Lifesciences, an innovator in nutraceutical solutions, today announced the publication of a cli
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# U of A Launches Rapamycin Clinical Trial with Philanthropic Support of Alumnus Ken Coit April 1, 2026 Researchers at the University of Arizona R. Ken Coit College of Pharmacy will begin a double-bli
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The official web resource of the TAME Trial, managed by the American Federation for Aging Research. ... #### The Targeting Aging with Metformin (TAME) Trial is a series of nationwide, six-year clinica
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***From cellular recycling to cognitive aging, spermidine is drawing scientific interest, but the evidence needed for routine human use is still emerging.** * ... Review findings highlighted that whil
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Based on a randomized controlled trial of berberine (registered in ClinicalTrials.gov on Dec 2018, NCT03770325), leveraging proteomics and sex hormones data, we built a signature reflecting response t
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In a pre-specified ancillary study of the VITaminD and omegA-3 (VITAL) trial, we examined the effect of 1 g of marine omega-3 FA per day, comprised of 460 mg eicosapentanoic acid and 380 mg of docosah
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In preclinical models and laboratory model organisms, collagen supplementation increases the health and lifespan of rats 30, Drosophila 31, and C. elegans 32, 33, suggesting that collagen supplementat
Here we provide the evidence in a 2 × 6-week randomized, double-blind, placebo-controlled, crossover clinical trial that chronic supplementation with the NAD + precursor vitamin, nicotinamide riboside
You can set your browser to block or alert you about these cookies, but some parts of the site will not then work.
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We conducted the search through PubMed, Embase, and Web of Science databases from inception to April 30th, 2025, to identify meta-analyses of randomized controlled trials examining the effects of resv
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This research marks the initial exploration into the safety of a new high-p spermid trihydroide supplement (hpSPD) for human use. ... In this randomized, double-blind, placebo-controlled trial, 37 hea
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## RBR-78bcfbc Effect of Curcumin on gut health and inflammatory aspects in Overweight and Obese individuals Date of registration: 07/08/2026 ^(mm/dd/yyyy)^ Last approval date : 07/08/2026 ^(mm/dd/yyy
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## RBR-4cdm4k4 Study evaluating the effect of resveratrol on pain in women with lipedema Date of registration: 07/03/2026 ^(mm/dd/yyyy)^ Last approval date : 07/03/2026 ^(mm/dd/yyyy)^ ### Study type:
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## RBR-2b7hw6b Impact of Resveratrol on the health of individuals with type 2 Diabetes Date of registration: 06/06/2026 ^(mm/dd/yyyy)^ Last approval date : 06/06/2026 ^(mm/dd/yyyy)^ ### Study type: In
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Sources verified July 31, 2026 ... - **Study type** Randomized, placebo-controlled, quadruple-masked Phase 2 trial - **Studied in** 129 enrolled; 114 completers aged 50–85 analyzed - **Publication sta
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**Start:** August 2021 **End:** March 2026 **Enrollment:** 40 This Phase 2 study will evaluate the safety and effects of rapamycin, an FDA-approved anti-fungal medication, in older adults with mild co
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Pterostilbene is more bioavailable than resveratrol, but only a few clinical trials have tested it alone, so more evidence is needed. ... However, no clinical trials have confirmed these effects in h
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## Palvella Therapeutics Announces First Patients Dosed in Phase 2 LOTU Trial of Fast Track-Designated QTORIN™ Rapamycin for Clinically Significant Angiokeratomas May 4, 2026 ... *Phase 2 single-arm,
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We report results from the largest randomized, double-blind, placebo-controlled trial of nicotinamide mononucleotide (NMN) supplementation to date. Over 12 months, participants receiving 500 mg/day NM
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## A Clinical Trial to Assess the Absorption, Safety, and Efficacy of an Oral Nicotinamide Adenine Dinucleotide (NAD+) Supplement in Healthy Adults ClinicalTrials.gov ID ** NCT07692633 Sponsor ** Reus
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## Assessment of the Effects and Safety of Spermidine Supplementation on Blood Lipids and Body Weight in Overweight or Obese Individuals With Hyperlipidemia ClinicalTrials.gov ID ** NCT07662330 Sponso
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## Nicotinamide Riboside, Vit B3 Analogue, and Brain Energy Metabolism ClinicalTrials.gov ID ** NCT07649161 Sponsor ** Massachusetts General Hospital Information provided by ** MOHAMED, SOLIMAN, Massa
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## Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients (ALA-MYO-PCOS) ClinicalTrials.gov ID ** NCT07630779 Sponsor ** Beni-Suef University Information provided by **
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## Effects of Omega-3 Fatty Acids on Inflammation and Gut Microbiota in Celiac Disease (OMEGA-CD) ClinicalTrials.gov ID ** NCT07585669 Sponsor ** University of Chile Information provided by ** Univers
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Not yet recruiting** ## Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial) (ROSS) ClinicalTrials.gov ID ** NCT07579429 Sponsor ** University of Colorado, Denver Information provi
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## Alpha-Lipoic Acid in Mitigating Cisplatin-Induced Nephrotoxicity ClinicalTrials.gov ID ** NCT07564479 Sponsor ** Minia University Information provided by ** Asmaa Bassem Mohammed, Minia University
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Not yet recruiting** ## Effects of Berberine on Cardiometabolic Outcomes ClinicalTrials.gov ID ** NCT07541898 Sponsor ** University of Central Lancashire Information provided by ** Jonathan Sinclair,
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Completed** ## Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men (HIITCRECOG) ClinicalTrials.gov ID ** NCT07534293 Sponsor ** U
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Completed** ## Effect of Curcumin Add-On Therapy on Quality of Life and IL-1β Levels in Patients With Schizophrenia (CUR-SCZ) ClinicalTrials.gov ID ** NCT07523256 Sponsor ** Rinvil Renaldi Information
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Completed** ## Magnesium Supplementation With Fluoxetine for Cognitive Function in Depression (MAG-DEP) ClinicalTrials.gov ID ** NCT07521358 Sponsor ** Hasanuddin University Information provided by **
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## Short-Term Safety of Low-Dose Creatine Hydrochloride: A 28-Day Single-Arm Pilot Study ClinicalTrials.gov ID ** NCT07521059 Sponsor ** Vireo Systems, Inc. ... Last Update Posted ** 2026-04-09 **Comp
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## Effect of Magnesium Supplementation on Sleep Quality and Cognitive Function in Saudi Adults ClinicalTrials.gov ID ** NCT07515417 Sponsor ** Umm Al-Qura University ... Last Update Posted ** 2026-08-
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Clinical Trial # Project SIRT6 Activator Recruiting ... Fucoidan, a sulfated polysaccharide from brown macroalgae, is a safe dietary supplement with Sirtuin-6 (SIRT6) activating properties, which are
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Not yet recruiting** ## Can People Achieve a Target Omega-3 Index by Following a Personalized Omega-3 Dosing Regimen? ClinicalTrials.gov ID ** NCT07480707 Sponsor ** Fatty Acid Research Institute Info
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## Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat ClinicalTrials.gov ID ** NCT07472426 Sponsor ** University of Northern Iowa I
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## Study on the Efficacy of Quercetin Intake in Patients With Fibrotic Interstitial Lung Diseases. ClinicalTrials.gov ID ** NCT07466420 Sponsor ** Katerina M. Antoniou Information provided by ** Kater
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Not yet recruiting** ## Berberine Phytosome for Signs and Symptoms of Polycystic Ovary Syndrome (PCOS) ClinicalTrials.gov ID ** NCT07465575 Sponsor ** Liaquat University of Medical & Health Sciences I
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Not yet recruiting** ## Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease C
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Study identifier: **NCT07383311** Synced from ClinicalTrials.gov · August 10, 2026 ● Study status: RecruitingSpSleep # Autophagy-Enhancers to Reduce Sleep Disturbances Condition: Mild Cognitive Impair
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## Evaluation of the Pharmacokinetics of Curcumin Capsules in Healthy HumanClinicalTrials.gov ID ## Study Overview Main objective: Through blood drug concentration testing, evaluate the post-meal phar
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## Influence of the Urolithin A on the Population With BMI Higher Than 30 During Restricted Eating. (Obesity UroA) ClinicalTrials.gov ID ** NCT07377136 Sponsor ** Charles University, Czech Republic In
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## NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down SyndromeClinicalTrials.gov ID ## Study Overview Specific Aims / Objectives Primary Aim To determine the safety and tol
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## Supplementation With Sirtuin Activators in Women With Increased Body WeightClinicalTrials.gov ID ## Study Overview The goal of this clinical trial is to learn if the six-month supplementation with
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## Fisetin Supplementation for Healthy Aging (Fisetin LOW)ClinicalTrials.gov ID ... The investigators will conduct a clinical trial in healthy volunteers, who will receive supplementation with fisetin
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## Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults ClinicalTrials.gov ID ** NCT07144527 Sponsor ** Scott Silveira ... Last Update Posted ** 2026-
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## Creatine and Resistance Training in Older Adults With Mild Cognitive Impairment ClinicalTrials.gov ID ** NCT06948149 Sponsor ** Western University, Canada ... Last Update Posted ** 2026-05-19 **Rec
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## Study of High-Dose Resveratrol in Patients With Stable Ischemic Heart DiseaseClinicalTrials.gov ID ## Study Overview Dietary Supplement: High-dose resveratrol 500 mg/day Other: Placebo - SW028 ## C
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## Effects Of Daily Taurine Intake For 6 Months On Biological Age and Body Metabolism Indicators As Well As Physical Fitness In 55-75-year-old Women And Men (TauAge)ClinicalTrials.gov ID ## Study Over
## Intervention of Nicotinamide Mononucleotide in Middle-aged and Elderly People (NMNAGING) ClinicalTrials.gov ID ** NCT06592859 Sponsor ** People's Hospital of Quzhou Information provided by ** Feng
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## NAD+ Oral Supplement Pilot Intervention in Adult Females ClinicalTrials.gov ID ** NCT06579209 Sponsor ** University of Rhode Island Information provided by ** University of Rhode Island (Responsibl
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# FIRST Fisetin to Reduce Senescence and Mobility Impairment in Peripheral Artery Disease: the FIRST Pilot Randomized Trial Qué se está evaluando ... ## Estudio de Tratamiento Controlado con PlaceboFa
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## Oral Bioavailability of a New Formulation of Pterostilbene Cocrystal in Comparison With Its Free Form (BIOPTERO2) (BIOPTERO2)ClinicalTrials.gov ID ## Study Overview The goal of this interventional
## Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical TrialClinicalTrials.gov ID ## Study Overview ... Uroli
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## The NADage Study: Nicotinamide Riboside Replenishment Therapy Against Functional Decline in Aging (NADage)ClinicalTrials.gov ID ## Study Overview This clinical study, designed as a double-blind, ra
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## Effects of an Omega-3 Fatty Acid-based Supplement on Healthy AgeingClinicalTrials.gov ID ... The goal of this randomised, double-blind placebo controlled trial is to explore tolerability and the ef
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Recruiting Phase 1 Phase 2 ## Fisetin Fisetin to Improve Vascular Function in Older Adults Sponsor: University of Colorado, Boulder Code: NCT06133634 Conditions Aging Endothelial Dysfunction Arterial
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## Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt (MIRACLE-ALA)ClinicalTrials.gov ID ## Study Overview This is a multicenter, interve
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Active, not recruiting** ## Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure ClinicalTrials.gov ID ** NCT05690464 Sponsor ** Brigham and Women's Hospital ... The purpose of this
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The purpose of this study is to investigate the effects of quercetin supplementation on bone, specifically on bone turnover markers, in postmenopausal women. The interplay between cytokines (i.e., IL-
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Active Not Recruiting NA INTERVENTIONAL 2-arm NCT04562831 # The NO-ALS Study: A Trial of Nicotinamide/Pterostilbene Supplement in ALS. A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbe
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**Verified**by 2020-01 Last known status was: Recruiting ## Basis: Evaluating Sirtuin Supplements To Benefit Elderly Trauma Patients (BES2T BET) (BestBet)ClinicalTrials.gov ID ## Study Overview Basis:
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## Omega-3 Fatty Acid in Treating Patients With Stage I-III Breast CancerClinicalTrials.gov ID ## Study Overview PRIMARY OBJECTIVES: I. To determine if omega-3 dietary supplementation (omega-3 fatty a
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## Vitamin D and Omega-3 Trial (VITAL) (VITAL) ClinicalTrials.gov ID ** NCT01169259 Sponsor ** Brigham and Women's Hospital ... Last Update Posted ** 2026-07-30 **Active, not recruiting** ** No longer
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**The trial:** A 12-week, double-blind, randomised, placebo-controlled phase-II pilot of nicotinamide riboside, 500 mg twice daily, in adults aged 65 and over with amnestic mild cognitive impairment.
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# Metformin Shows Promise for Slowing Cellular Aging in Prediabetic Adults Six-month trial examines whether metformin treatment can improve telomere length and longevity gene expression in prediabetic
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This Phase 2 clinical trial evaluated the safety and efficacy of LipokonTM Berberine and Berberine extract as an adjunct to oral hypoglycemic agents (OHAs). Methods: In this double-blind, parallel-ar
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This trial will test the hypothesis that geroprotectors targeted towards biological mechanisms associated with poor resilience can reverse these pathways within a three-week period. Three geroprotecto
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Published in IJPHDT, Vol-3, Issue-04, April-2026 (Vol. 3, Issue 4, 2026) ... Objective: This systematic review sought to rigorously investigate randomized controlled trials (RCTs) regarding the effica
713-798-4710 Houston, TX ... A randomized, double blind human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC – a combination of glycine
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Last reviewed: 2026-04-12Version 1Next review: approx. 12 monthsForm studied: Oral L-glycine at 3 g taken before bedtime for sleep outcomes; doses of 5–15 g/day studied for metabolic outcomes ... Thes
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Front. Nutr., 21 July 2026 Sec. Nutrition and Metabolism Volume 13 - 2026 | https://doi.org/10.3389/fnut.2026.1834344 … ... Urolithin A (UA), a gut microbiota–derived metabolite, has been proposed to
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Neurol., 10 August 2026 Sec. ... Volume 17 - 2026 | https://doi.org/10.3389/fneur.2026.1904967 … ... This study evaluates and ranks their efficacy and safety through a Bayesian network meta-analysis (
Received 14th April 2026 , Accepted 6th June 2026 First published on 15th June 2026 ## Abstract ... Taurine supplementation has shown promising outcomes in human studies, with emerging relevance in pr
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|Unique ID issued by UMIN|UMIN000062041| ... |Receipt number|R000070989| |Scientific Title|Single-ingredient Vitamin D3 3200 IU versus Vitamin D3 3200 IU/Zinc/Quercetin Supplementation in Adult Indone
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Last updated: June 1, 2026 Sponsor: University of Utah Overall Status: Active - Recruiting #### Phase 3 #### Condition Urologic Cancer Metastatic Cancer Prostate Cancer, Early, Recurrent #### Treatmen
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- ### FDA Greenlights Life Biosciences’ Human Study, Setting Up Pivotal Test for Aging Theory from Harvard’s David Sinclair Jan 30, 2026 - ### A Natural Senolytic Supplement Curbs Heart Aging in New C
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# NCT07657390 Nicotinamide riboside/Pterostilbene Cancer Pain Clinical Landscape Report 2026: Design, Endpoints, Sponsor and Readout Outlook 4 August 2026 ... *MCP evidence snapshot: 4 August 2026. Tr
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# The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial ``` @article{Lopresti2026TheEO, title={The
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# TauAge randomised, controlled pilot trial: Does taurine supplementation with 4 g/day for 6 months slow human ageing? Subject Area Biogerontology and Geriatric Medicine Term since 2026 Project identi
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Jeyakodi S et al. Int J Clin Trials. 2026 Aug;13(3):270-282 ... Original Research Article Metaberine (bio-optimised berberine 200 mg/day) improves metabolic health markers in healthy adults: a rando
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Status: Enrolling # Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial Phase II Age ≥18 Sponsor National Cancer Institu
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# Curcumin Supplementation Reduces Inflammation, Neutrophil-to-Lymphocyte Ratio (NLR), and Antioxidant Status in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial by Metha Yaikwawong
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Pencina · The Journal of clinical endocrinology and metabolism 2023 · randomized controlled trial · n=30 # Nicotinamide Adenine Dinucleotide Augmentation in Overweight or Obese Middle-Aged and Older A
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Schwarz C, Benson GS, Horn N, et al. Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial. JAMA Netw Open. 2
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British Journal of Nutrition Accepted manuscript # Impact of creatine monohydrate supplementation combined with multicomponent training in older adults (≥75 years): study protocol of a randomized cont
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**Background/Objectives**: Nicotinamide mononucleotide (NMN), a precursor of nicotinamide adenine dinucleotide (NAD^+^), is used as a dietary supplement, but its safety and metabolic effects in adults
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Reduced nicotinamide mononucleotide (NMNH) is a reduced NAD⁺ precursor with reported NAD⁺- augmenting activity in preclinical models; however, controlled human data remain limited. This was a randomiz
The effect of a low-calorie Mediterranean diet, intermittent fasting, and natural senolytics on aging markers in participants with low and high vascular risk Submission date 04/01/2026 Registration
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A new meta-analysis led by researchers from the Fatty Acid Research Institute (FARI) provides the clearest picture to date of the relationship between omega-3 fatty acid supplementation and atrial fib
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- # Tuna Meat Enhances Mitochondrial Function and Antioxidant Capacity via Nicotinamide Adenine Dinucleotide-Sirtuin Activation in Humans: A Clinical Trial Study ... - **Source:** Current Nutrition &
# Low-dose oral nicotinamide mononucleotide for immune thrombocytopenia: a phase 1/2 trial Nat Med. 2026 Jun;32(6):2026-2036. doi: 10.1038/s41591-026-04366-x. Epub 2026 Apr 29. ... Based on these find
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# San Antonio's Barshop Institute to test three approved drugs for slowing aging ... At UT Health San Antonio’s Sam and Ann Barshop Institute, researchers are preparing a major new test of an old scie
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The overall mission of our institute is to make **fundamental scientific discoveries about the ageing process**. In doing so, we aim to elucidate the molecular, physiological and evolutionary mechanis
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NIA Caenorhabditis Interventions Testing Program (CITP) Announces Annual Call for Compounds to Test for Lifespan Extension in Caenorhabditis Notice Number: NOT-AG-26-005 ## Key Dates Release Date: A
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NIA Intervention Testing Program (ITP) Announces Annual Call for Compounds to Test for Lifespan Extension in Mice Notice Number: NOT-AG-25-014 ## Key Dates Release Date: February 18, 2026 ## Related
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Home Newsroom Newsroom All Press release Media Echo Video Select type All Press release Media Echo Video Unexpected help from vitamin B12 August 07, 2026 Antebi Drugs Press release Basic research on w
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21.05.2026 13:01 * ... As we age, our cells lose energy and adaptability—a process closely linked to the function of mitochondria, the cell’s “powerhouses”. Researchers at the Leibniz Institute on Agi
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The goal is to improve immune resilience, enhance protection against disease and ultimately support healthier ageing. ... ## Media contact ### Tom Cramp E: t.cramp@ucl.ac.uk ##
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Study identifier: **NCT06813261** Synced from ClinicalTrials.gov · August 18, 2026 ● Study status: RecruitingGRACE # GLYLO Supplement Pilot Trial on Glycation and Aging in Postmenopausal Women Conditi
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### The killifish reveals in fast-forward what takes decades in humans: chronic inflammation, DNA damage in precursor cells and remodelling processes in the blood-forming organ characterise the ageing
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06/22/2026 · News · Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut · Lebenswissenschaften · Forschungsergebnis A review article now published in “Nature Reviews Genetics” brings togeth
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The Interventions Testing Program (ITP) is a peer-reviewed program designed to identify agents that extend lifespan and healthspan in mice. Investigators at any university, institute, company, or othe
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The IHA is a centre of excellence for research on the biology of ageing and ageing related diseases. ... 06 Nov in person Understanding evolution through game theory: Insights from students and resear
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### 15th AHA Conference ### 1st EFAR Conference ... New CECAD Postdoc Academy for Aging Trajectories! ### Apply Now! For PhD-Programme at the Cologne Graduate School of Ageing Research!
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New policy notes from UCL IHE, Policy Impact Unit and CelebrAGE set out the challenges and opportunities of an ageing population. **Healthy Ageing Symposium: living better for longer** Bringing togeth
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# Half-time seminars Half-time Seminar: Martin Nilsson 02-09-2026 1:30 pm Add to iCal Campus Solna Karolina lecture hall, Widerströmska huset, Tomtebodavägen 18a, Solna "Multimodal neuroimaging of mem
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# Half-time seminars Half-time Seminar: Franziska Steffens 27-08-2026 9:30 am - 12:00 pm Add to iCal Campus Solna Karolina lecture hall, Widerströmska huset, Tomtebodavägen 18a, Solna "Old-age depress
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Published: 26-03-2026 10:27 | Updated: 26-03-2026 10:57 ... A group of senior leaders from Flemish organisations working with older people (In4Care) visited the Aging Research Center (ARC) at Karolins
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Home Events Public Events Scientific Events All Events Upcoming Lectures and Events Cologne Seminars on Ageing "Directing differentiation, maturation and age in human PSC-derived neurons" Date: Sep 3,
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Het **ERIBA** (afkorting van *European Research Institute of the Biology of Ageing*) is een onderzoeksinstituut van het Universitair Medisch Centrum Groningen en de Rijksuniversiteit Groningen waar we
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## Media contact ## Mark Greaves m.greaves [at] ucl.ac.uk +44 (0)20 3108 9485 ##
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We aim to elucidate the molecular, physiological and evolutionary mechanisms underlying ageing. ... ## Events ### #### Cologne Seminars on Ageing "Directing differentiation, maturation and age in huma
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Leyden Academy visits the Aging Research Center (ARC) and TraCeDem at Karolinska Institutet on 21 May 2026. ... On 21 May 2026, a delegation from Leyden Academy on Vitality and Ageing visited the Agin
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The first EFAR conference will take place in Cologne, 14–16 October 2026, providing a platform for scientists across Europe to exchange knowledge and foster new partnerships in ageing research.
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### #69 - Dr. Valter Longo | Fasting, Longevity & Disease Prevention | Director of the USC Longevity InstituteJan 13 2026 Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they sp
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Published: 05-12-2025 18:39 | Updated: 20-04-2026 18:40 ... The Aging Research Center (ARC) celebrated its 25th anniversary on 1 December 2025, with an afternoon filled with reflections, presentations
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Amy Wagers, associate professor of stem cell and regenerative biology at Harvard University and the Joslin Diabetes Center, has joined the Paul F. Glenn Laboratories for the Biological Mechanisms of A
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The Interventions Testing Program (ITP) tests potential agents that may delay aging as measured by lifespan extension and/or delayed onset/severity of late life pathologies. The ITP is funded by four
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Symposium on Aging The 2026 Paul F. Glenn Center for the Biology of Aging Research BLAVATNIK INSTITUTE HARVARD MEDICAL SCHOOL The Paul F. Glenn Center for the Biology of Aging Research Each year the C
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CONFERENCE ON THE BIOLOGY OF AGING 39th Annual Glenn AFAR Grantee Conference Ritz-Carlton Bacara, Santa Barbara, California May 27 - 29, 2026 … The Paul F. Glenn/AFAR Conference on the Biology of A
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**When & Where: ** **Date: 14th - 16th October 2026** **Venue: MPI for Biology of Ageing & CECAD Research Center, Cologne, Germany** **You can now register for the event in our Registration Tool:** **
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Each year, a conference is organized for scientists, clinicians, engineers, and students to exchange research results and ideas on translational research on aging. ... **When & Where: ** **Date: 11th
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BEER-SHEVA, Israel, April 20, 2026 – New research from Ben-Gurion University of the Negev has found a critical role for the SIRT6 enzyme in preventing the formation of protein waste. SIRT6 is a natura
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Glycation Reduction and Aging, a Clinical Evaluation (GRACE) CLOSED Sugar-stress-lowering supplement for postmenopausal women #### GRACE STUDY ###### RECRUITING IS CLOSED Glycation stress is something
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A double-blind trial in EClinicalMedicine gave 58 adults with long COVID nicotinamide riboside 2000 mg per day. NAD+ rose within 5 weeks. Cognition did not improve on any of three tests, with p-values
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A Norwegian 2x2 factorial trial randomised 310 adults with long COVID to nicotinamide riboside 2000 mg per day or placebo for 84 days. Data collection ended 23 June 2025. The registry was updated 22 A
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Two new trial records were reviewed and neither changes a rating. A published protocol for 100 mg fisetin daily over 7 weeks in adults aged 50 and older reports no results, so fisetin stays at grade C
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Issues | The Journals of Gerontology: Series B | The Journals of Gerontology: Series B Volume 81, Issue Supplement_1, February 2026 Harmonization Recommendations from the Gateway to Global Aging Data
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Expert reviews rank fisetin and quercetin as top senolytics, with spermidine and resveratrol as supporting players in longevity supplement stacks. ... A comprehensive review of popular longevity suppl
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The goal of our analysis was to test the hypothesis that vitamin D supplementation, omega-3 supplementation and a simple home exercise program (SHEP), individually and in combination, would slow biolo
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This randomized, double-blind, placebo-controlled trial evaluated the effects of sodium hyaluronate (SH) supplementation at two daily doses on skin parameters in healthy Caucasian adults. A total of 1
- Rigorous new human research found whole-blood NAD+ levels don't decline with age, challenging the core premise behind NAD+ supplements, including NMN. - The clinical evidence that NMN and other NAD+
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## Effects of Miricell Supplementation on Biomarkers of Healthy Aging and Autophagy ClinicalTrials.gov ID ** NCT07675200 Sponsor ** Nutraland USA, Inc. ... Last Update Posted ** 2026-06-30 **Recruitin
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A new 2026 *Cell Metabolism* study by Maura Fanti and colleagues gives the longevity-diet debate a more precise target than “eat less protein.” In aged mice, the group tested a low-amino-acid pattern
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Volume 81, Issue 8 August 2026 Cover image ... #### THE JOURNAL OF GERONTOLOGY: Biological Sciences ... ##### Effect of inactivation of the USP19 deubiquitinase gene in mice on important phenotypes of
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# The Lancet Healthy Longevity Homepage Download started.Ok ... #### Emulating target trials in older adults with multimorbidityPublished: July 28, 2025Older adults aged 75 years and older with multim
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A landmark 2026 longitudinal cohort study published in *Nature Metabolism* has provided the most robust clinical evidence to date that the age-related decline in **mitochondrial oxidative phosphorylat
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### 2026, Volume 81, Issue Supplement_1 - **1-3 Introduction: Harmonization Recommendations from the Gateway to Global Aging Data** *by* Jinkook Lee & Jere R Behrman - **4-6 NIA perspective on harmoni
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The Lancet Healthy Longevity•June 30, 2026•Blossom C M Stephan, Jennifer Dunne, Jacob Brain, Leanne Greene, Serena Sabatini, Amanda Eddy-Lacey, Bronwyn Myers, Tanya Buchanan, Katherine Ride, James C V
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But This Research Really Could Change Humanity.A new therapy has the potential to cure hundreds of diseases — and even reverse aging.Credit...Photo illustration by Kensuke KoikeSupported bySKIP ADVERT
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The Journals of Gerontology: Series A | Oxford Academic Latest Issue Volume 81 Issue 9 September 2026 #### Editors-in-Chief ... This new section of the journal brings the opportunity for all discipli
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DUBAI, 5th February, 2026 (WAM) -- Ageing could soon be treated as a medical condition rather than an inevitable part of life, with scientists moving closer to reversing the biological clock, accordin
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Aging Cell. 2026 Feb;25(2):e70371. doi: 10.1111/acel.70371. ... - DOI: 10.1111/acel.70371 ... Aging is a multifactorial process influenced by genetic, environmental, and metabolic factors. Dysregulate
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A daily multivitamin–multimineral supplement significantly slowed certain markers of biological ageing after 2 years of treatment in a study involving 958 older adults. The results, published in *Natu
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Volume 81, Issue 3 March 2026 Cover image ... EISSN 1758-535X ... #### THE JOURNAL OF GERONTOLOGY: Biological Sciences ... ##### From rash to resilience: how herpes zoster vaccination may influence in
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The Lancet Healthy Longevity 2026 Showing papers in "The Lancet Healthy Longevity in 2026" Journal Article 10.1016/j.lanhl.2026.100818 Thank you to The Lancet Healthy Longevity statistical and peer re
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You are viewing 4 eligible products in USP Verified. Last updated: Jun 2, 2026 View all Clean & Third-Party Tested SupplementsNSF Certified · 22USP Verified · 4Organic Supplements · 36Vegan Supplement
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The U.S. Pharmacopeia (USP) has been named a participating certifier in Amazon's new Compliance Fast-Track Program for dietary supplements. This recognition means products bearing the USP Verified Mar
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Posted on August 21st 2026 ... In this clip, Dr. Rhonda Patrick shares her supplement routine, dosing strategies, brand preferences, and why she uses omega-3s, melatonin, and...
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This is why NSF developed the nation's first independent testing standard and product certification program strictly for dietary supplements. The program protects consumers by testing for harmful leve
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Annual Report · April 2026 ... By Derek Giordano · ~18 minute read · Last updated April 29, 2026 ... Three developments define 2025–2026. First, the **PEARL trial published its results**, delivering t
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In this clip from a FoundMyFitness Premium Member Q&A episode, Rhonda updates listeners on her current supplement routine. ... - Her preferred supplement brands & dosing ... So I'm going to go ahead a
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Expert reviews compare NMN and NR head-to-head. NMN edges out for muscle and sleep benefits; NR leads for neuroprotection. ... Two leading NAD+ precursor supplements — NMN and NR — have been compared
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# Great HealthWorks' OmegaXL Sport Earns Prestigious NSF Certified for Sport® Designation *OmegaXL Sport verified free of 290+ banned substances, achieving the gold standard in athletic safety and joi
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Last updated on 21 Apr, 2026 Examine helps you understand what the research says about nutrition, supplements, and health — clearly and without bias from ads, sponsors, or partnerships.
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Reference #18.930a3d17.1743087055.4ca7c39
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This interactive database depicts the status of the most significant clinical trials of longevity-related therapies.
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NSF’s Certified for Sport® testing program helps confirm that sports supplements and sports nutritional products do not contain substances banned by many major athletic organizations. ... This indepen
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# The 23rd World Congress of the International Association of Gerontology and Geriatrics - 2026 ## Congress details It is pleasure to invite you to attend the 23 ^rd^IAGG World Conference in Amsterdam
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#### GSA 2026 in National Harbor, MD Join your colleagues at the premier Annual Scientific Meeting for fields related to gerontology. ... #### Free registration with booth purchase! Reserve your 2026
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Volume 57 | Issue No 01 | January 2026 The Gerontological Society of ... This resilience, both individual and collective, aligns with the theme of the 2026 Annual Scientific Meeting, “Reinforcing R
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The 13^th^ Aging Research & Drug Discovery (ARDD) Meeting, the world's largest conference dedicated to longevity biotechnology, will take place from October 1-3, 2026, at the David Rubenstein Treehous
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## GSA 2026 Scientific Meeting November 4 - 7 | National Harbor, MD. Visit gsa2026.org ### Important Updates **Early Bird Registration—** Closes September 1, 11:59 PM ET **Now Open— ** Register | Book
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Gerontological Society of America • 2026 Annual Scientific Meeting Gerontological Society of America (GSA) 2026 Annual Scientific Meeting Reinforcing Resilience in Aging Science, Research, and Educ
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BOSTON, MA — Aug 20, 2026 — Insilico Medicine (“Insilico”), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company and organizer of the 13th Aging Research & Drug Discov
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“*The 12th Aging Research and Drug Discovery (ARDD) meeting convened at the University of Copenhagen, presenting a comprehensive overview of recent advancements in the biology of aging*.*”* **BUFFALO,
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1985 New York NY USA ... Promote biomedical *aging* studies directed towards increasing the functional life span of humans; keep the public informed of the progress of aging research and of practical
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# U of A launches rapamycin clinical trial with philanthropic support of alumnus Ken Coit ... March 30, 2026 Researchers at the University of Arizona R. Ken Coit College of Pharmacy will begin a doubl
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The official web resource of the TAME Trial, managed by the American Federation for Aging Research. ... #### The Targeting Aging with Metformin (TAME) Trial is a series of nationwide, six-year clinica
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***From cellular recycling to cognitive aging, spermidine is drawing scientific interest, but the evidence needed for routine human use is still emerging.** * ... In a recent 'Article in Press' review
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Based on a randomized controlled trial of berberine (registered in ClinicalTrials.gov on Dec 2018, NCT03770325), leveraging proteomics and sex hormones data, we built a signature reflecting response t
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In a pre-specified ancillary study of the VITaminD and omegA-3 (VITAL) trial, we examined the effect of 1 g of marine omega-3 FA per day, comprised of 460 mg eicosapentanoic acid and 380 mg of docosah
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Here we provide the evidence in a 2 × 6-week randomized, double-blind, placebo-controlled, crossover clinical trial that chronic supplementation with the NAD + precursor vitamin, nicotinamide riboside
These cookies are necessary for the website to function and cannot be switched off in our systems.
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We conducted the search through PubMed, Embase, and Web of Science databases from inception to April 30th, 2025, to identify meta-analyses of randomized controlled trials examining the effects of resv
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Dietary glycine increases healthy lifespan in model organisms and might decrease inflammation in humans, suggesting its geroprotective potential. This review summarises the evidence of glycine adminis
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You can set your browser to block or alert you about these cookies, but some parts of the site will not then work.
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This research marks the initial exploration into the safety of a new high-p spermid trihydroide supplement (hpSPD) for human use. ... In this randomized, double-blind, placebo-controlled trial, 37 hea
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## RBR-78bcfbc Effect of Curcumin on gut health and inflammatory aspects in Overweight and Obese individuals Date of registration: 07/08/2026 ^(mm/dd/yyyy)^ Last approval date : 07/08/2026 ^(mm/dd/yyy
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## RBR-4cdm4k4 Study evaluating the effect of resveratrol on pain in women with lipedema Date of registration: 07/03/2026 ^(mm/dd/yyyy)^ Last approval date : 07/03/2026 ^(mm/dd/yyyy)^ ### Study type:
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## RBR-2b7hw6b Impact of Resveratrol on the health of individuals with type 2 Diabetes Date of registration: 06/06/2026 ^(mm/dd/yyyy)^ Last approval date : 06/06/2026 ^(mm/dd/yyyy)^ ### Study type: In
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Sources verified July 31, 2026 ... - **Study type** Randomized, placebo-controlled, quadruple-masked Phase 2 trial - **Studied in** 129 enrolled; 114 completers aged 50–85 analyzed - **Publication sta
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**Start:** August 2021 **End:** March 2026 **Enrollment:** 40 This Phase 2 study will evaluate the safety and effects of rapamycin, an FDA-approved anti-fungal medication, in older adults with mild co
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Last updated: May 16, 2026 Sponsor: Ove Andersen Overall Status: Active - Recruiting #### Phase 1/2 #### Condition N/A #### Treatment Fisetin Placebo #### Clinical Study ID NCT06431932 Fisetin HIGH 20
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## Palvella Therapeutics Announces First Patients Dosed in Phase 2 LOTU Trial of Fast Track-Designated QTORIN™ Rapamycin for Clinically Significant Angiokeratomas May 4, 2026 ... *Phase 2 single-arm,
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We report results from the largest randomized, double-blind, placebo-controlled trial of nicotinamide mononucleotide (NMN) supplementation to date. Over 12 months, participants receiving 500 mg/day NM
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## A Clinical Trial to Assess the Absorption, Safety, and Efficacy of an Oral Nicotinamide Adenine Dinucleotide (NAD+) Supplement in Healthy Adults ClinicalTrials.gov ID ** NCT07692633 Sponsor ** Reus
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## Assessment of the Effects and Safety of Spermidine Supplementation on Blood Lipids and Body Weight in Overweight or Obese Individuals With Hyperlipidemia ClinicalTrials.gov ID ** NCT07662330 Sponso
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## Phase II, Randomized, Double-blind, Placebo-controlled Clinical Trial to Evaluate the Efficacy and Safety of Omega-3 Fatty Acids as an Adjunct to Morphine in Acute Postoperative Pain (O3MORPH) Clin
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## Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients (ALA-MYO-PCOS) ClinicalTrials.gov ID ** NCT07630779 Sponsor ** Beni-Suef University Information provided by **
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Not yet recruiting** ## Effects of Creatine and Heat Exposure on Exercise Performance and Body Water Distribution ClinicalTrials.gov ID ** NCT07593014 Sponsor ** University of Windsor Information prov
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Not yet recruiting** ## RESvEraTrol in Parkinson's Disease (RESET) (RESET) ClinicalTrials.gov ID ** NCT07592767 Sponsor ** Georgetown University ... Last Update Posted ** 2026-05-18 Study Details Rese
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## Effects of Omega-3 Fatty Acids on Inflammation and Gut Microbiota in Celiac Disease (OMEGA-CD) ClinicalTrials.gov ID ** NCT07585669 Sponsor ** University of Chile Information provided by ** Univers
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Not yet recruiting** ## Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial) (ROSS) ClinicalTrials.gov ID ** NCT07579429 Sponsor ** University of Colorado, Denver Information provi
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## Alpha-Lipoic Acid in Mitigating Cisplatin-Induced Nephrotoxicity ClinicalTrials.gov ID ** NCT07564479 Sponsor ** Minia University ... Last Update Posted ** 2026-05-04 Study Details Researcher View
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Not yet recruiting** ## Effects of Berberine on Cardiometabolic Outcomes ClinicalTrials.gov ID ** NCT07541898 Sponsor ** University of Central Lancashire Information provided by ** Jonathan Sinclair,
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Completed** ## Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men (HIITCRECOG) ClinicalTrials.gov ID ** NCT07534293 Sponsor ** U
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Completed** ## Magnesium Supplementation With Fluoxetine for Cognitive Function in Depression (MAG-DEP) ClinicalTrials.gov ID ** NCT07521358 Sponsor ** Hasanuddin University Information provided by **
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## Short-Term Safety of Low-Dose Creatine Hydrochloride: A 28-Day Single-Arm Pilot Study ClinicalTrials.gov ID ** NCT07521059 Sponsor ** Vireo Systems, Inc. ... Last Update Posted ** 2026-04-09 **Comp
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## Effect of Magnesium Supplementation on Sleep Quality and Cognitive Function in Saudi Adults ClinicalTrials.gov ID ** NCT07515417 Sponsor ** Umm Al-Qura University ... Last Update Posted ** 2026-04-
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Clinical Trial # Project SIRT6 Activator Recruiting Summary ... Fucoidan, a sulfated polysaccharide from brown macroalgae, is a safe dietary supplement with Sirtuin-6 (SIRT6) activating properties, wh
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Not yet recruiting** ## Can People Achieve a Target Omega-3 Index by Following a Personalized Omega-3 Dosing Regimen? ClinicalTrials.gov ID ** NCT07480707 Sponsor ** Fatty Acid Research Institute ...
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## Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat ClinicalTrials.gov ID ** NCT07472426 Sponsor ** University of Northern Iowa I
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## Study on the Efficacy of Quercetin Intake in Patients With Fibrotic Interstitial Lung Diseases. ClinicalTrials.gov ID ** NCT07466420 Sponsor ** Katerina M. Antoniou ... Last Update Posted ** 2026-0
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Not yet recruiting** ## Berberine Phytosome for Signs and Symptoms of Polycystic Ovary Syndrome (PCOS) ClinicalTrials.gov ID ** NCT07465575 Sponsor ** Liaquat University of Medical & Health Sciences I
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Not yet recruiting** ## Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease C
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Study identifier: **NCT07383311** Synced from ClinicalTrials.gov · August 10, 2026 ● Study status: RecruitingSpSleep # Autophagy-Enhancers to Reduce Sleep Disturbances Condition: Mild Cognitive Impair
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## Evaluation of the Pharmacokinetics of Curcumin Capsules in Healthy HumanClinicalTrials.gov ID ## Study Overview Main objective: Through blood drug concentration testing, evaluate the post-meal phar
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## Influence of the Urolithin A on the Population With BMI Higher Than 30 During Restricted Eating. (Obesity UroA) ClinicalTrials.gov ID ** NCT07377136 Sponsor ** Charles University, Czech Republic In
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## NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down SyndromeClinicalTrials.gov ID ... Specific Aims / Objectives Primary Aim To determine the safety and tolerability of m
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## Supplementation With Sirtuin Activators in Women With Increased Body WeightClinicalTrials.gov ID ## Study Overview The goal of this clinical trial is to learn if the six-month supplementation with
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## Fisetin Supplementation for Healthy Aging (Fisetin LOW)ClinicalTrials.gov ID ## Study Overview ... The investigators will conduct a clinical trial in healthy volunteers, who will receive supplement
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## Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults ClinicalTrials.gov ID ** NCT07144527 Sponsor ** Scott Silveira ... Last Update Posted ** 2026-
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Recruiting soon # Omega-3 Fatty Acid Supplementation for Adult and Juvenile Dermatomyositis What is being tested ## FISH OIL 500MG OMEGA-3 SOFT GEL MINIS + Placebo Dietary Supplement Who is being recr
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## Creatine and Resistance Training in Older Adults With Mild Cognitive Impairment ClinicalTrials.gov ID ** NCT06948149 Sponsor ** Western University, Canada ... Last Update Posted ** 2026-05-19 ... T
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## Effects Of Daily Taurine Intake For 6 Months On Biological Age and Body Metabolism Indicators As Well As Physical Fitness In 55-75-year-old Women And Men (TauAge)ClinicalTrials.gov ID ## Study Over
## Intervention of Nicotinamide Mononucleotide in Middle-aged and Elderly People (NMNAGING) ClinicalTrials.gov ID ** NCT06592859 Sponsor ** People's Hospital of Quzhou Information provided by ** Feng
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## NAD+ Oral Supplement Pilot Intervention in Adult Females ClinicalTrials.gov ID ** NCT06579209 Sponsor ** University of Rhode Island Information provided by ** University of Rhode Island (Responsibl
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# FIRST Fisetin to Reduce Senescence and Mobility Impairment in Peripheral Artery Disease: the FIRST Pilot Randomized Trial Qué se está evaluando ... ## Estudio de Tratamiento Controlado con PlaceboFa
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## The NADage Study: Nicotinamide Riboside Replenishment Therapy Against Functional Decline in Aging (NADage)ClinicalTrials.gov ID ## Study Overview This clinical study, designed as a double-blind, ra
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Recruiting Phase 1 Phase 2 ## Fisetin Fisetin to Improve Vascular Function in Older Adults Sponsor: University of Colorado, Boulder Code: NCT06133634 Conditions Aging Endothelial Dysfunction Arterial
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## Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative NeoplasmsClinicalTrials.gov I
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## Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO TrialClinicalTrials.gov ID ## Study Overview PRIMARY OBJECTIVE: I. To d
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## Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt (MIRACLE-ALA)ClinicalTrials.gov ID ## Study Overview This is a multicenter, interve
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Active, not recruiting** ## Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure ClinicalTrials.gov ID ** NCT05690464 Sponsor ** Brigham and Women's Hospital ... The purpose of this
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The purpose of this study is to investigate the effects of quercetin supplementation on bone, specifically on bone turnover markers, in postmenopausal women. The interplay between cytokines (i.e., IL-
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Recruiting NA INTERVENTIONAL 1-arm NCT05095571 # A Trial of Nicotinamide/Pterostilbene Supplement in ALS: The NO-ALS Extension Study A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbene
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Active Not Recruiting NA INTERVENTIONAL 2-arm NCT04562831 # The NO-ALS Study: A Trial of Nicotinamide/Pterostilbene Supplement in ALS. A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbe
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## Vitamin D and Omega-3 Trial (VITAL) (VITAL) ClinicalTrials.gov ID ** NCT01169259 Sponsor ** Brigham and Women's Hospital ... Last Update Posted ** 2026-07-30 **Active, not recruiting** ** No longer
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# Metformin Shows Promise for Slowing Cellular Aging in Prediabetic Adults Six-month trial examines whether metformin treatment can improve telomere length and longevity gene expression in prediabetic
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**Jupiter, FL, May 27, 2026 (GLOBE NEWSWIRE) -- ** Jupiter Neurosciences, Inc. (NASDAQ: JUNS), a clinical-stage biopharmaceutical company developing investigational therapies for neurodegenerative dis
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This trial will test the hypothesis that geroprotectors targeted towards biological mechanisms associated with poor resilience can reverse these pathways within a three-week period. Three geroprotecto
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**Methods:**In this double-blind, prospective, placebo-controlled trial (NCT05735886) we sought to characterize for the first time the effects of UA on the human immune system. Fifty healthy participa
Homa Shalchi 713-798-4710 Houston, TX ... A randomized, double blind human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC – a combinatio
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GeroScience: Oral LNAD+ rapidly elevates whole blood intracellular NAD and metabolic flux without elevating plasma NAD: evidence from a randomized controlled trial July 30, 2026 View Source ... This a
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Front. Aging, 13 May 2026 Sec. ... Volume 7 - 2026 | https://doi.org/10.3389/fragi.2026.1773667 # Nicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the
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Neurol., 10 August 2026 ... Volume 17 - 2026 | https://doi.org/10.3389/fneur.2026.1904967 … ... Alpha-lipoic acid (ALA) is widely utilized for diabetic peripheral neuropathy (DPN); however, optimal ad
Received 14th April 2026 , Accepted 6th June 2026 First published on 15th June 2026 ## Abstract ... Taurine supplementation has shown promising outcomes in human studies, with emerging relevance in pr
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|Unique ID issued by UMIN|UMIN000062041| ... |Receipt number|R000070989| |Scientific Title|Single-ingredient Vitamin D3 3200 IU versus Vitamin D3 3200 IU/Zinc/Quercetin Supplementation in Adult Indone
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- ### FDA Greenlights Life Biosciences’ Human Study, Setting Up Pivotal Test for Aging Theory from Harvard’s David Sinclair Jan 30, 2026 - ### A Natural Senolytic Supplement Curbs Heart Aging in New C
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# NCT07657390 Nicotinamide riboside/Pterostilbene Cancer Pain Clinical Landscape Report 2026: Design, Endpoints, Sponsor and Readout Outlook 4 August 2026 ... *MCP evidence snapshot: 4 August 2026. Tr
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- DOI:10.3389/fnut.2025.1729164 ... # The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial ``` @ar
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Project Details # TauAge randomised, controlled pilot trial: Does taurine supplementation with 4 g/day for 6 months slow human ageing? Subject Area Biogerontology and Geriatric Medicine Term since 202
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Jeyakodi S et al. Int J Clin Trials. 2026 Aug;13(3):270-282 ... Original Research Article Metaberine (bio-optimised berberine 200 mg/day) improves metabolic health markers in healthy adults: a rando
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**Objectives**: Conduct a randomized double-blind placebo-controlled crossover pilot trial on adults with nonclinical insomnia symptoms to examine the effectiveness of magnesium supplementation on sle
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Status: Enrolling # Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial Phase II Age ≥18 Sponsor National Cancer Institu
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Status: Enrolling # Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms Ph
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Schwarz C, Benson GS, Horn N, et al. Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial. JAMA Netw Open. 2
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British Journal of Nutrition Accepted manuscript # Impact of creatine monohydrate supplementation combined with multicomponent training in older adults (≥75 years): study protocol of a randomized cont
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**Everolimus Aging Study (NCT05835999)** - **What’s being done:** low-dose everolimus to test whether mTORC1 inhibition can improve physiological and molecular hallmarks of aging. ... - **Phase / stat
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NAD-HD is a double-blind randomized controlled multicenter trial investigating the effect of nicotinamide riboside supplement as a potential disease-modifying treatment in Huntington’s disease. The st
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**Background/Objectives**: Nicotinamide mononucleotide (NMN), a precursor of nicotinamide adenine dinucleotide (NAD^+^), is used as a dietary supplement, but its safety and metabolic effects in adults
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*Curr. Issues Mol. Biol.* **2026**, *48*(2), 216; https://doi.org/10.3390/cimb48020216 Submission received: 17 January 2026 / Revised: 13 February 2026 / Accepted: 15 February 2026 / Published: 16 Feb
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Importance: Preclinical and human observational studies suggest that metformin may decrease age-related pathology, including frailty. Objective: Determine whether metformin reduces frailty progression
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# Berberine shows no advantage over placebo for reducing liver and belly fat ... A multicenter research effort in China conducted clinical trial testing of oral berberine for six months in diabetes-fr
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# Low-dose oral nicotinamide mononucleotide for immune thrombocytopenia: a phase 1/2 trial Nat Med. 2026 Jun;32(6):2026-2036. doi: 10.1038/s41591-026-04366-x. Epub 2026 Apr 29. ... Based on these find
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**Open Call for available White Space in the CECAD Research Center** **The CECAD Excellence Cluster on Aging and Aging-associated Diseases seeks independently funded research groups to join and suppor
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# San Antonio's Barshop Institute to test three approved drugs for slowing aging ... At UT Health San Antonio’s Sam and Ann Barshop Institute, researchers are preparing a major new test of an old scie
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The overall mission of our institute is to make **fundamental scientific discoveries about the ageing process**. In doing so, we aim to elucidate the molecular, physiological and evolutionary mechanis
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Publicerad: 2026-04-23 11:12 | Uppdaterad: 2026-04-23 15:12 ... Verksamhetsrapporten 2023–2025 ger en översikt av Aging Research Center (ARC):s tvärvetenskapliga forskning om hjärnans åldrande, demens
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NIA Caenorhabditis Interventions Testing Program (CITP) Announces Annual Call for Compounds to Test for Lifespan Extension in Caenorhabditis Notice Number: NOT-AG-26-005 ## Key Dates Release Date: A
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NIA Intervention Testing Program (ITP) Announces Annual Call for Compounds to Test for Lifespan Extension in Mice Notice Number: NOT-AG-25-014 ## Key Dates Release Date: February 18, 2026 ## Related
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Longevity Center | Europe provides a comprehensive approach to health through its advanced diagnostics and personalized longevity plans. Uniquely, it utilizes the Longevity Center Method, addressing e
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### The killifish reveals in fast-forward what takes decades in humans: chronic inflammation, DNA damage in precursor cells and remodelling processes in the blood-forming organ characterise the ageing
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06/22/2026 · News · Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut · Lebenswissenschaften · Forschungsergebnis A review article now published in “Nature Reviews Genetics” brings togeth
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The Interventions Testing Program (ITP) is a peer-reviewed program designed to identify agents that extend lifespan and healthspan in mice. Investigators at any university, institute, company, or othe
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The IHA is a centre of excellence for research on the biology of ageing and ageing related diseases. ... 06 Nov in person Understanding evolution through game theory: Insights from students and resear
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To better characterise the ageing process, researchers have begun to identify and categorise the cellular and **molecular hallmarks of ageing** [López-Otín et al. 2013 & 2023, Kennedy et al. 2014]. It
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**Healthy Ageing Symposium: living better for longer** Bringing together academics, industry leaders and charity representatives, the event aimed to address the challenges of ageing healthily. In part
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# Half-time seminars Half-time Seminar: Martin Nilsson 02-09-2026 1:30 pm Add to iCal Campus Solna Karolina lecture hall, Widerströmska huset, Tomtebodavägen 18a, Solna "Multimodal neuroimaging of mem
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## Institute of Healthy Ageing (IHA) The Institute of Healthy Ageing is a world-class centre of excellence for research focussed on the biology of ageing and ageing-related diseases.
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Published: 26-03-2026 10:27 | Updated: 26-03-2026 10:57 ... A group of senior leaders from Flemish organisations working with older people (In4Care) visited the Aging Research Center (ARC) at Karolins
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Home Events Public Events Scientific Events All Events Upcoming Lectures and Events Cologne Seminars on Ageing "Talk title to be confirmed" Date: Sep 3, 2026 Time: 01:00 PM - 02:00 PM (Local Time Germ
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**European Research Institute for the Biology of Ageing** ( **ERIBA**) is a nonprofit research facility based in Groningen, Netherlands, concerned with cross-disciplinary research on ageing.
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## Media contact ## Mark Greaves m.greaves [at] ucl.ac.uk +44 (0)20 3108 9485 ##
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We aim to elucidate the molecular, physiological and evolutionary mechanisms underlying ageing. ... ## Events ### #### Cologne Seminars on Ageing "Talk title to be confirmed" Sep 3, 2026 01:00 PM - 02
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Researchers have investigated the role played by the cell membrane lipid phosphatidylcholine in this process — and have identified a potential approach to healthy aging. 05/27/2026 · News · Leibniz-In
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Leyden Academy visits the Aging Research Center (ARC) and TraCeDem at Karolinska Institutet on 21 May 2026. ... On 21 May 2026, a delegation from Leyden Academy on Vitality and Ageing visited the Agin
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To read the full opinion piece (DOI 10.1038/s43587-026-01128-9) visit Nature Aging: Connecting fragmented aging research through the European Federation for Aging Research
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### #69 - Dr. Valter Longo | Fasting, Longevity & Disease Prevention | Director of the USC Longevity InstituteJan 13 2026 Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they sp
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This clinical trial portfolio at the Buck Institute for Research on Aging shifts focus from chronic disease treatment to proactive physiological optimization across diverse human cohorts. Central to t
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Symposium on Aging The 2026 Paul F. Glenn Center for the Biology of Aging Research BLAVATNIK INSTITUTE HARVARD MEDICAL SCHOOL The Paul F. Glenn Center for the Biology of Aging Research Each year the C
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CONFERENCE ON THE BIOLOGY OF AGING 39th Annual Glenn AFAR Grantee Conference Ritz-Carlton Bacara, Santa Barbara, California May 27 - 29, 2026 … The Paul F. Glenn/AFAR Conference on the Biology of A
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**When & Where: ** **Date: 14th - 16th October 2026** **Venue: MPI for Biology of Ageing & CECAD Research Center, Cologne, Germany** **You can now register for the event in our Registration Tool:** **
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**When & Where: ** **Date: 11th - 13th October 2026** **Venue: MPI for Biology of Ageing & CECAD Research Center, Cologne, Germany** ... |17:30 – 19:00|Postdoc event|(by registration only)| ... |19:00
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**BUFFALO, NY — August 10, 2026 — ** A new essay was published in Volume 18 of *Aging* on August 6, 2026, titled “Misha Blagosklonny: a life of ideas.” ... **Paper DOI**: https://doi.org/10.18632/agin
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Glycation Reduction and Aging, a Clinical Evaluation (GRACE) CLOSED Sugar-stress-lowering supplement for postmenopausal women #### GRACE STUDY ###### RECRUITING IS CLOSED Glycation stress is something
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1,000 mg is the amount of omega-3 that Quten's Qunol page says each serving provides. A federal court complaint reports that an ISO/IEC 17025-accredited laboratory measured 26.9% omega-3 in purchased
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Issues | The Journals of Gerontology: Series B | The Journals of Gerontology: Series B Volume 81, Issue Supplement_1, February 2026 Harmonization Recommendations from the Gateway to Global Aging Data
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Expert reviews rank fisetin and quercetin as top senolytics, with spermidine and resveratrol as supporting players in longevity supplement stacks. ... A comprehensive review of popular longevity suppl
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This randomized, double-blind, placebo-controlled trial evaluated the effects of sodium hyaluronate (SH) supplementation at two daily doses on skin parameters in healthy Caucasian adults. A total of 1
This prespecified ancillary study evaluated the 2-year effect of a daily MVM (Centrum Silver) and cocoa extract (500 mg cocoa flavanols per day, including 80 mg (−)-epicatechin) on five DNA methylatio
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Journal• ISSN: 1549-1684 ... About: Rejuvenation Research is an academic journal published by Mary Ann Liebert, Inc.. The journal publishes majorly in the area(s): Medicine & Biology. It has an ISSN i
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- Rigorous new human research found whole-blood NAD+ levels don't decline with age, challenging the core premise behind NAD+ supplements, including NMN. - The clinical evidence that NMN and other NAD+
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近日，《eBioMedicine》期刊发表一篇重磅研究Contributions of inherited mtDNA to longevity: evidence from extended pedigrees with 176 million kinship pairs，通过海量数据复盘，终于揭开了母系长寿的核心秘密——线粒体DNA（mtDNA），才是悄悄镌刻在我们基因里的长寿密码。 不同于我
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## Effects of Miricell Supplementation on Biomarkers of Healthy Aging and Autophagy ClinicalTrials.gov ID ** NCT07675200 Sponsor ** Nutraland USA, Inc. ... Last Update Posted ** 2026-06-30 **Recruitin
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Volume 81, Issue 8 August 2026 Cover image ... #### THE JOURNAL OF GERONTOLOGY: Biological Sciences ... ##### Effect of inactivation of the USP19 deubiquitinase gene in mice on important phenotypes of
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# The Lancet Healthy Longevity Homepage Download started.Ok ... #### Emulating target trials in older adults with multimorbidityPublished: July 28, 2025Older adults aged 75 years and older with multim
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A landmark 2026 longitudinal cohort study published in *Nature Metabolism* has provided the most robust clinical evidence to date that the age-related decline in **mitochondrial oxidative phosphorylat
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### 2026, Volume 81, Issue Supplement_1 - **1-3 Introduction: Harmonization Recommendations from the Gateway to Global Aging Data** *by* Jinkook Lee & Jere R Behrman - **4-6 NIA perspective on harmoni
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The Lancet Healthy Longevity•June 30, 2026•Blossom C M Stephan, Jennifer Dunne, Jacob Brain, Leanne Greene, Serena Sabatini, Amanda Eddy-Lacey, Bronwyn Myers, Tanya Buchanan, Katherine Ride, James C V
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DUBAI, 5th February, 2026 (WAM) -- Ageing could soon be treated as a medical condition rather than an inevitable part of life, with scientists moving closer to reversing the biological clock, accordin
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Aging Cell. 2026 Feb;25(2):e70371. doi: 10.1111/acel.70371. ... - DOI: 10.1111/acel.70371 ... Aging is a multifactorial process influenced by genetic, environmental, and metabolic factors. Dysregulate
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A daily multivitamin–multimineral supplement significantly slowed certain markers of biological ageing after 2 years of treatment in a study involving 958 older adults. The results, published in *Natu
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Volume 81 Issue 9 | The Journals of Gerontology: Series A | Oxford Academic Volume 81, Issue 9 September 2026 (In Progress) ... - Special Issue: Animal Models of Frailty - Special Issue: How HIV Affe
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Introduction: Harmonization Recommendations from the Gateway to Global Aging Data | The Journals of Gerontology: Series B | Oxford Academic ** Volume 81 Issue Supplement_1 February 2026 # Introductio
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Reference #18.870f3417.1743024077.b6d06a8
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The U.S. Pharmacopeia (USP) has been named a participating certifier in Amazon's new Compliance Fast-Track Program for dietary supplements. This recognition means products bearing the USP Verified Mar
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- Diet: A whole-food, minimally processed, plant-based diet, high in complex carbohydrates and low in harmful fats and refined sugars.
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This is why NSF developed the nation's first independent testing standard and product certification program strictly for dietary supplements. The program protects consumers by testing for harmful leve
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### Certified Products Results Your search for **all products** returned the results below.
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## Q&A #83 with Dr. Rhonda Patrick (7/18/26)
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BRIDGEWATER, N.J. and MUMBAI, India, Aug. 10, 2026 /PRNewswire/ -- OmniActive Health Technologies (OmniActive) today announced that Zenroot, a root-only, standardized ashwagandha extract with clinical
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**Volume 12, Issue 4** — April 2026 | Special Issue: Peptides, Senolytics & the New Longevity Toolbox ## Clinical Trial ... 156 Clinical Trials Tracked 423 Reviews Published ... Clinical Trial ### Sen
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# Great HealthWorks' OmegaXL Sport Earns Prestigious NSF Certified for Sport® Designation *OmegaXL Sport verified free of 290+ banned substances, achieving the gold standard in athletic safety and joi
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Last updated on 21 Apr, 2026 Examine helps you understand what the research says about nutrition, supplements, and health — clearly and without bias from ads, sponsors, or partnerships.
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Reference #18.930a3d17.1743087055.4ca7c39
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This interactive database depicts the status of the most significant clinical trials of longevity-related therapies.
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NSF’s Certified for Sport® testing program helps confirm that sports supplements and sports nutritional products do not contain substances banned by many major athletic organizations. ... This indepen
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All seven hinge on purity and stability, not dose alone. ... **Brand comparison: YourHealthier, ProHealth (Uthever®), Alive By Science, Renue By Science, scored across key quality criteria** |Criteria
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# The 23rd World Congress of the International Association of Gerontology and Geriatrics - 2026 ## Congress details It is pleasure to invite you to attend the 23 ^rd^IAGG World Conference in Amsterdam
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#### GSA 2026 in National Harbor, MD Join your colleagues at the premier Annual Scientific Meeting for fields related to gerontology. ... #### Free registration with booth purchase! Reserve your 2026
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Join us in National Harbor, MD, for the GSA Annual Scientific Meeting. Connect with professionals, attend scientific sessions and workshops, and learn from award-winning speakers. Enhance your knowled
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The 13^th^ Aging Research & Drug Discovery (ARDD) Meeting, the world's largest conference dedicated to longevity biotechnology, will take place from October 1-3, 2026, at the David Rubenstein Treehous
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**04-21-2026** “*The 12th Aging Research and Drug Discovery (ARDD) meeting convened at the University of Copenhagen, presenting a comprehensive overview of recent advancements in the biology of aging*
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## GSA 2026 Scientific Meeting November 4 - 7 | National Harbor, MD. Visit gsa2026.org ### Important Updates **Early Bird Registration—** Closes September 1, 11:59 PM ET **Now Open— ** Register | Book
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# Aging Research and Drug Discovery Meeting 2026 Copenhagen (København) (ARDD 2026) ... **The 13th Aging Research and Drug Discovery Meeting 2026 (ARDD 2026) will take place in late August / early Sep
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Gerontological Society of America • 2026 Annual Scientific Meeting Gerontological Society of America (GSA) 2026 Annual Scientific Meeting Reinforcing Resilience in Aging Science, Research, and Educ
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1985 New York NY USA ... Promote biomedical *aging* studies directed towards increasing the functional life span of humans; keep the public informed of the progress of aging research and of practical
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Hyderabad, August 17, 2026: Zeus Hygia Lifesciences, an innovator in nutraceutical solutions, today announced the publication of a clinical study evaluating Metaberine®, its bio-optimised berberine fo
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# Tai Chi/Qi Gong and Alpha Lipoic Acid with or without Acupuncture for the Treatment of Chemotherapy-Induced Peripheral Neuropathy for Patients with Stage I-III Colorectal Cancer This clinical trial
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# U of A launches rapamycin clinical trial with philanthropic support of alumnus Ken Coit ... March 30, 2026 Researchers at the University of Arizona R. Ken Coit College of Pharmacy will begin a doubl
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***From cellular recycling to cognitive aging, spermidine is drawing scientific interest, but the evidence needed for routine human use is still emerging.** * ... In a recent 'Article in Press' review
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Based on a randomized controlled trial of berberine (registered in ClinicalTrials.gov on Dec 2018, NCT03770325), leveraging proteomics and sex hormones data, we built a signature reflecting response t
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In a pre-specified ancillary study of the VITaminD and omegA-3 (VITAL) trial, we examined the effect of 1 g of marine omega-3 FA per day, comprised of 460 mg eicosapentanoic acid and 380 mg of docosah
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These cookies are necessary for the website to function and cannot be switched off in our systems.
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We conducted the search through PubMed, Embase, and Web of Science databases from inception to April 30th, 2025, to identify meta-analyses of randomized controlled trials examining the effects of resv
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This research marks the initial exploration into the safety of a new high-p spermid trihydroide supplement (hpSPD) for human use. ... In this randomized, double-blind, placebo-controlled trial, 37 hea
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## RBR-78bcfbc Effect of Curcumin on gut health and inflammatory aspects in Overweight and Obese individuals Date of registration: 07/08/2026 ^(mm/dd/yyyy)^ Last approval date : 07/08/2026 ^(mm/dd/yyy
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##### Public trial ## RBR-4cdm4k4 Study evaluating the effect of resveratrol on pain in women with lipedema Date of registration: 07/03/2026 ^(mm/dd/yyyy)^ Last approval date : 07/03/2026 ^(mm/dd/yyyy
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## RBR-2b7hw6b Impact of Resveratrol on the health of individuals with type 2 Diabetes Date of registration: 06/06/2026 ^(mm/dd/yyyy)^ Last approval date : 06/06/2026 ^(mm/dd/yyyy)^ ### Study type: In
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**Start:** August 2021 **End:** March 2026 **Enrollment:** 40 This Phase 2 study will evaluate the safety and effects of rapamycin, an FDA-approved anti-fungal medication, in older adults with mild co
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## Palvella Therapeutics Announces First Patients Dosed in Phase 2 LOTU Trial of Fast Track-Designated QTORIN™ Rapamycin for Clinically Significant Angiokeratomas May 4, 2026 ... *Phase 2 single-arm,
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# Harvard Study: NMN Shows 18% Improvement in VO2 Max for Older Adults First large-scale NMN trial (N=240) shows significant aerobic capacity improvements in adults 60+. Published in Cell Metabolism.
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We report results from the largest randomized, double-blind, placebo-controlled trial of nicotinamide mononucleotide (NMN) supplementation to date. Over 12 months, participants receiving 500 mg/day NM
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## A Clinical Trial to Assess the Absorption, Safety, and Efficacy of an Oral Nicotinamide Adenine Dinucleotide (NAD+) Supplement in Healthy Adults ClinicalTrials.gov ID ** NCT07692633 Sponsor ** Reus
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## Assessment of the Effects and Safety of Spermidine Supplementation on Blood Lipids and Body Weight in Overweight or Obese Individuals With Hyperlipidemia ClinicalTrials.gov ID ** NCT07662330 Sponso
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## Phase II, Randomized, Double-blind, Placebo-controlled Clinical Trial to Evaluate the Efficacy and Safety of Omega-3 Fatty Acids as an Adjunct to Morphine in Acute Postoperative Pain (O3MORPH) Clin
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## Nicotinamide Riboside, Vit B3 Analogue, and Brain Energy Metabolism ClinicalTrials.gov ID ** NCT07649161 Sponsor ** Massachusetts General Hospital Information provided by ** MOHAMED, SOLIMAN, Massa
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## Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients (ALA-MYO-PCOS) ClinicalTrials.gov ID ** NCT07630779 Sponsor ** Beni-Suef University Information provided by **
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## Effects of Omega-3 Fatty Acids on Inflammation and Gut Microbiota in Celiac Disease (OMEGA-CD) ClinicalTrials.gov ID ** NCT07585669 Sponsor ** University of Chile Information provided by ** Univers
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Not yet recruiting** ## Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial) (ROSS) ClinicalTrials.gov ID ** NCT07579429 Sponsor ** University of Colorado, Denver Information provi
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## Alpha-Lipoic Acid in Mitigating Cisplatin-Induced Nephrotoxicity ClinicalTrials.gov ID ** NCT07564479 Sponsor ** Minia University ... Last Update Posted ** 2026-05-04 Study Details Researcher View
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Not yet recruiting** ## Effects of Berberine on Cardiometabolic Outcomes ClinicalTrials.gov ID ** NCT07541898 Sponsor ** University of Central Lancashire Information provided by ** Jonathan Sinclair,
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Completed** ## Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men (HIITCRECOG) ClinicalTrials.gov ID ** NCT07534293 Sponsor ** U
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Completed** ## Effect of Curcumin Add-On Therapy on Quality of Life and IL-1β Levels in Patients With Schizophrenia (CUR-SCZ) ClinicalTrials.gov ID ** NCT07523256 Sponsor ** Rinvil Renaldi ... Last Up
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Completed** ## Magnesium Supplementation With Fluoxetine for Cognitive Function in Depression (MAG-DEP) ClinicalTrials.gov ID ** NCT07521358 Sponsor ** Hasanuddin University Information provided by **
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## Short-Term Safety of Low-Dose Creatine Hydrochloride: A 28-Day Single-Arm Pilot Study ClinicalTrials.gov ID ** NCT07521059 Sponsor ** Vireo Systems, Inc. ... Last Update Posted ** 2026-04-09 **Comp
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## Effect of Magnesium Supplementation on Sleep Quality and Cognitive Function in Saudi Adults ClinicalTrials.gov ID ** NCT07515417 Sponsor ** Umm Al-Qura University ... Last Update Posted ** 2026-04-
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Clinical Trial # Project SIRT6 Activator Recruiting Summary ... Fucoidan, a sulfated polysaccharide from brown macroalgae, is a safe dietary supplement with Sirtuin-6 (SIRT6) activating properties, wh
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Not yet recruiting** ## Can People Achieve a Target Omega-3 Index by Following a Personalized Omega-3 Dosing Regimen? ClinicalTrials.gov ID ** NCT07480707 Sponsor ** Fatty Acid Research Institute ...
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## Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat ClinicalTrials.gov ID ** NCT07472426 Sponsor ** University of Northern Iowa I
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## Study on the Efficacy of Quercetin Intake in Patients With Fibrotic Interstitial Lung Diseases. ClinicalTrials.gov ID ** NCT07466420 Sponsor ** Katerina M. Antoniou ... Last Update Posted ** 2026-0
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Not yet recruiting** ## Berberine Phytosome for Signs and Symptoms of Polycystic Ovary Syndrome (PCOS) ClinicalTrials.gov ID ** NCT07465575 Sponsor ** Liaquat University of Medical & Health Sciences I
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Not yet recruiting** ## Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease C
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## Evaluation of the Pharmacokinetics of Curcumin Capsules in Healthy HumanClinicalTrials.gov ID ## Study Overview Main objective: Through blood drug concentration testing, evaluate the post-meal phar
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## Influence of the Urolithin A on the Population With BMI Higher Than 30 During Restricted Eating. (Obesity UroA) ClinicalTrials.gov ID ** NCT07377136 Sponsor ** Charles University, Czech Republic In
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## NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down SyndromeClinicalTrials.gov ID ... Specific Aims / Objectives Primary Aim To determine the safety and tolerability of m
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## Supplementation With Sirtuin Activators in Women With Increased Body WeightClinicalTrials.gov ID ## Study Overview The goal of this clinical trial is to learn if the six-month supplementation with
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## Fisetin Supplementation for Healthy Aging (Fisetin LOW)ClinicalTrials.gov ID ## Study Overview ... The investigators will conduct a clinical trial in healthy volunteers, who will receive supplement
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## Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults ClinicalTrials.gov ID ** NCT07144527 Sponsor ** Scott Silveira ... Last Update Posted ** 2026-
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## Creatine and Resistance Training in Older Adults With Mild Cognitive Impairment ClinicalTrials.gov ID ** NCT06948149 Sponsor ** Western University, Canada ... Last Update Posted ** 2026-05-19 ... T
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## Impact of Creatine Monohydrate Micronized Supplementation With or Without Multicomponent Training in Older Adults. (CREAGED)ClinicalTrials.gov ID ## Study Overview The goal of this clinical trial i
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## Effects Of Daily Taurine Intake For 6 Months On Biological Age and Body Metabolism Indicators As Well As Physical Fitness In 55-75-year-old Women And Men (TauAge)ClinicalTrials.gov ID ## Study Over
## Intervention of Nicotinamide Mononucleotide in Middle-aged and Elderly People (NMNAGING) ClinicalTrials.gov ID ** NCT06592859 Sponsor ** People's Hospital of Quzhou Information provided by ** Feng
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## NAD+ Oral Supplement Pilot Intervention in Adult Females ClinicalTrials.gov ID ** NCT06579209 Sponsor ** University of Rhode Island Information provided by ** University of Rhode Island (Responsibl
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## Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With MultimorbidityClinicalTrials.gov ID ... We will conduct a clinical trial in healthy volunteers and older patients with multiple
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# FIRST Fisetin to Reduce Senescence and Mobility Impairment in Peripheral Artery Disease: the FIRST Pilot Randomized Trial Qué se está evaluando ... ## Estudio de Tratamiento Controlado con PlaceboFa
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## The NADage Study: Nicotinamide Riboside Replenishment Therapy Against Functional Decline in Aging (NADage)ClinicalTrials.gov ID ## Study Overview This clinical study, designed as a double-blind, ra
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Recruiting Phase 1 Phase 2 ## Fisetin Fisetin to Improve Vascular Function in Older Adults Sponsor: University of Colorado, Boulder Code: NCT06133634 Conditions Aging Endothelial Dysfunction Arterial
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## Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative NeoplasmsClinicalTrials.gov I
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## Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt (MIRACLE-ALA)ClinicalTrials.gov ID ## Study Overview This is a multicenter, interve
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## Urolithin A Supplementation to Boost Immune HealthClinicalTrials.gov ID ## Study Overview Dietary Supplement: Softgel containing placebo Dietary Supplement: Softgel containing 250mg of Urolithin A
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Active, not recruiting** ## Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure ClinicalTrials.gov ID ** NCT05690464 Sponsor ** Brigham and Women's Hospital ... The purpose of this
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The purpose of this study is to investigate the effects of quercetin supplementation on bone, specifically on bone turnover markers, in postmenopausal women. The interplay between cytokines (i.e., IL-
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Recruiting NA INTERVENTIONAL 1-arm NCT05095571 # A Trial of Nicotinamide/Pterostilbene Supplement in ALS: The NO-ALS Extension Study A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbene
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Active Not Recruiting NA INTERVENTIONAL 2-arm NCT04562831 # The NO-ALS Study: A Trial of Nicotinamide/Pterostilbene Supplement in ALS. A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbe
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**Verified**by 2020-01 Last known status was: Recruiting ## Basis: Evaluating Sirtuin Supplements To Benefit Elderly Trauma Patients (BES2T BET) (BestBet)ClinicalTrials.gov ID ## Study Overview Basis:
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## Effect of Pterostilbene on Cholesterol, Blood Pressure and Oxidative StressClinicalTrials.gov ID ## Study Overview Drug: Pterostilbene 50 mg twice daily Drug: Placebo Drug: Grape Extract Drug: Pter
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## Vitamin D and Omega-3 Trial (VITAL) (VITAL) ClinicalTrials.gov ID ** NCT01169259 Sponsor ** Brigham and Women's Hospital ... Last Update Posted ** 2026-07-30 **Active, not recruiting** ** No longer
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## Resveratrol for Improved Performance in the Elderly (RIPE)ClinicalTrials.gov ID ## Study Overview Dietary Supplement: Placebo Drug: Low dose Resveratrol Drug: High dose Resveratrol - 238-2009 ## Co
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## Alpha Omega Trial: Study of Omega-3 Fatty Acids and Coronary MortalityClinicalTrials.gov ID ## Study Overview The Alpha Omega Trial is a randomized, placebo-controlled, double-blind dietary interve
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# Metformin Shows Promise for Slowing Cellular Aging in Prediabetic Adults Six-month trial examines whether metformin treatment can improve telomere length and longevity gene expression in prediabetic
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This trial will test the hypothesis that geroprotectors targeted towards biological mechanisms associated with poor resilience can reverse these pathways within a three-week period. Three geroprotecto
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A randomized, double blind human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC – a combination of glycine and N-acetylcysteine – improv
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31 peer-reviewed studies curated from PubMed and Semantic Scholar. 1 Meta-analyses 1 Systematic reviews 14 RCTs 15 Other studies ... Systematic reviews (3%) RCTs (45%) Observational (3%) ... Systemati
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Aging, 13 May 2026 ... Volume 7 - 2026 | https://doi.org/10.3389/fragi.2026.1773667 # Nicotinamide riboside and pterostilbene reduces frequency and severity of undesirable symptoms of the menopause tr
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Neurol., 10 August 2026 ... Volume 17 - 2026 | https://doi.org/10.3389/fneur.2026.1904967 ... This study evaluates and ranks their efficacy and safety through a Bayesian network meta-analysis (NMA) eq
Received 14th April 2026 , Accepted 6th June 2026 First published on 15th June 2026 ## Abstract ... Taurine supplementation has shown promising outcomes in human studies, with emerging relevance in pr
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|Unique ID issued by UMIN|UMIN000062041| ... |Receipt number|R000070989| |Scientific Title|Single-ingredient Vitamin D3 3200 IU versus Vitamin D3 3200 IU/Zinc/Quercetin Supplementation in Adult Indone
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- ### FDA Greenlights Life Biosciences’ Human Study, Setting Up Pivotal Test for Aging Theory from Harvard’s David Sinclair Jan 30, 2026 - ### A Natural Senolytic Supplement Curbs Heart Aging in New C
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# NCT07657390 Nicotinamide riboside/Pterostilbene Cancer Pain Clinical Landscape Report 2026: Design, Endpoints, Sponsor and Readout Outlook 4 August 2026 ... *MCP evidence snapshot: 4 August 2026. Tr
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# ChiCTR2600123561 Nicotinamide riboside/Pterostilbene Adult Acute Myeloblastic Leukemia Clinical Landscape Report 2026: Design, Endpoints, Sponsor and Readout Outlook 24 July 2026 ... *MCP evidence s
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# A phase II randomized placebo-controlled study of fisetin to improve physical function in breast cancer survivors: the TROFFi study rationale and trial design Ther Adv Med Oncol. 2026 Mar 11:18:1758
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Project Details # TauAge randomised, controlled pilot trial: Does taurine supplementation with 4 g/day for 6 months slow human ageing? Subject Area Biogerontology and Geriatric Medicine Term since 202
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**Objectives**: Conduct a randomized double-blind placebo-controlled crossover pilot trial on adults with nonclinical insomnia symptoms to examine the effectiveness of magnesium supplementation on sle
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Status: Enrolling # Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial Phase II Age ≥18 Sponsor National Cancer Institu
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Status: Enrolling # Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms Ph
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# Curcumin Supplementation Reduces Inflammation, Neutrophil-to-Lymphocyte Ratio (NLR), and Antioxidant Status in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial by Metha Yaikwawong
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Schwarz C, Benson GS, Horn N, et al. Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial. JAMA Netw Open. 2
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British Journal of Nutrition Accepted manuscript # Impact of creatine monohydrate supplementation combined with multicomponent training in older adults (≥75 years): study protocol of a randomized cont
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**Everolimus Aging Study (NCT05835999)** - **What’s being done:** low-dose everolimus to test whether mTORC1 inhibition can improve physiological and molecular hallmarks of aging. ... **Rapalog Pharma
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NAD-HD is a double-blind randomized controlled multicenter trial investigating the effect of nicotinamide riboside supplement as a potential disease-modifying treatment in Huntington’s disease. The st
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**Background/Objectives**: Nicotinamide mononucleotide (NMN), a precursor of nicotinamide adenine dinucleotide (NAD^+^), is used as a dietary supplement, but its safety and metabolic effects in adults
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*Curr. Issues Mol. Biol.* **2026**, *48*(2), 216; https://doi.org/10.3390/cimb48020216 Submission received: 17 January 2026 / Revised: 13 February 2026 / Accepted: 15 February 2026 / Published: 16 Feb
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Importance: Preclinical and human observational studies suggest that metformin may decrease age-related pathology, including frailty. Objective: Determine whether metformin reduces frailty progression
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Published April 7, 2026 | Version v2.2.1 Software Open ... Systematic review and network meta-analysis comparing nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) supplementation on car
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## NCT05590468: An ongoing trial by Ralitza Gavrilova This trial is ongoing. It must report results 1 year, 4 months from now. ... |Full entry on ClinicalTrials.gov|NCT05590468| ... |Title|Randomized,
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Anxiety about the aging process - especially fears about declining health - may lead to changes in how genes function, contributing to accelerated aging, according to a study involving 726 midlife wom
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The Sam and Ann Barshop Institute for Longevity and Aging Studies at UT Health San Antonio, the academic health center of The University of Texas at San Antonio (UT San Antonio) will receive up to $38
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At the beginning of the year, a new research project was launched at the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) and Friedrich Schiller University in Jena. The joint “KreDiT RNA” re
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# San Antonio's Barshop Institute to test three approved drugs for slowing aging ... At UT Health San Antonio’s Sam and Ann Barshop Institute, researchers are preparing a major new test of an old scie
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The overall mission of our institute is to make **fundamental scientific discoveries about the ageing process**. In doing so, we aim to elucidate the molecular, physiological and evolutionary mechanis
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Healthy Weight and Healthy Ageing (2026). ... Date: 13/02/2026, 10am-11.30am Time
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Publicerad: 2026-04-23 11:12 | Uppdaterad: 2026-04-23 15:12 ... Verksamhetsrapporten 2023–2025 ger en översikt av Aging Research Center (ARC):s tvärvetenskapliga forskning om hjärnans åldrande, demens
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NIA Intervention Testing Program (ITP) Announces Annual Call for Compounds to Test for Lifespan Extension in Mice Notice Number: NOT-AG-25-014 ## Key Dates Release Date: February 18, 2026 ## Related
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July 17, 2026 Video Our video explains the biological processes behind ageing more “In the end, it’s always about people” July 15, 2026 Career Institute PhD Coordinator Daniela Morick on trust, commun
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05/21/2026 13:01 * ... As we age, our cells lose energy and adaptability—a process closely linked to the function of mitochondria, the cell’s “powerhouses”. Researchers at the Leibniz Institute on Agi
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#### Elisa Motori Receives Plus 3 Grant for Research on Brain Metastases ... Dr. Elisa Motori, principal investigator at the CECAD Research Center and the Center for Molecular Medicine Cologne (CMMC),
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A new editorial was published in Volume 18 of *Aging-US* on May 18, 2026, titled "Public health in the age of longevity interventions: from prevention to system-wide resilience." The editorial was aut
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Longevity Center | Europe provides a comprehensive approach to health through its advanced diagnostics and personalized longevity plans. Uniquely, it utilizes the Longevity Center Method, addressing e
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### The killifish reveals in fast-forward what takes decades in humans: chronic inflammation, DNA damage in precursor cells and remodelling processes in the blood-forming organ characterise the ageing
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The Interventions Testing Program (ITP) is a peer-reviewed program designed to identify agents that extend lifespan and healthspan in mice. Investigators at any university, institute, company, or othe
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The IHA is a centre of excellence for research on the biology of ageing and ageing related diseases. ... 06 Nov in person Understanding evolution through game theory: Insights from students and resear
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**Healthy Ageing Symposium: living better for longer** Bringing together academics, industry leaders and charity representatives, the event aimed to address the challenges of ageing healthily. In part
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# Half-time seminars Half-time Seminar: Martin Nilsson 02-09-2026 1:30 pm Add to iCal Campus Solna Karolina lecture hall, Widerströmska huset, Tomtebodavägen 18a, Solna "Multimodal neuroimaging of mem
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## Institute of Healthy Ageing (IHA) The Institute of Healthy Ageing is a world-class centre of excellence for research focussed on the biology of ageing and ageing-related diseases.
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Published: 26-03-2026 10:27 | Updated: 26-03-2026 10:57 ... A group of senior leaders from Flemish organisations working with older people (In4Care) visited the Aging Research Center (ARC) at Karolins
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Home Events Public Events Scientific Events All Events Upcoming Lectures and Events 3rd ASPIRE-GLIA Symposium Start: Aug 19, 2026 01:00 PM (Local Time Germany) End: Aug 21, 2026 01:00 PM Location: Jos
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Het **ERIBA** (afkorting van *European Research Institute of the Biology of Ageing*) is een onderzoeksinstituut van het Universitair Medisch Centrum Groningen en de Rijksuniversiteit Groningen waar we
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We aim to elucidate the molecular, physiological and evolutionary mechanisms underlying ageing. ... ## Events ### #### 3rd ASPIRE-GLIA Symposium Aug 19, 2026 01:00 PM (Local Time Germany) - Aug 21, 20
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Leyden Academy visits the Aging Research Center (ARC) and TraCeDem at Karolinska Institutet on 21 May 2026. ... On 21 May 2026, a delegation from Leyden Academy on Vitality and Ageing visited the Agin
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To read the full opinion piece (DOI 10.1038/s43587-026-01128-9) visit Nature Aging: Connecting fragmented aging research through the European Federation for Aging Research
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### #69 - Dr. Valter Longo | Fasting, Longevity & Disease Prevention | Director of the USC Longevity InstituteJan 13 2026 Send us a text Join Dr. Sandra Cammarata and Dr. Giovanni Campanile as they sp
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A multidisciplinary research center, established in 2000 by Stockholm University and Karolinska Institutet, with the mission to improve the health and well-being of older individuals by contributing t
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The Interventions Testing Program (ITP) tests potential agents that may delay aging as measured by lifespan extension and/or delayed onset/severity of late life pathologies. The ITP is funded by four
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Symposium on Aging The 2026 Paul F. Glenn Center for the Biology of Aging Research BLAVATNIK INSTITUTE HARVARD MEDICAL SCHOOL The Paul F. Glenn Center for the Biology of Aging Research Each year the C
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**When & Where: ** **Date: 14th - 16th October 2026** **Venue: MPI for Biology of Ageing & CECAD Research Center, Cologne, Germany** **You can now register for the event in our Registration Tool:** **
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**When & Where: ** **Date: 11th - 14th October 2026** **Venue: MPI for Biology of Ageing & CECAD Research Center, Cologne, Germany** **You can now register for the event in our Registration Tool:** ..
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**BUFFALO, NY — August 10, 2026 — ** A new essay was published in Volume 18 of *Aging* on August 6, 2026, titled “Misha Blagosklonny: a life of ideas.” ... **Paper DOI**: https://doi.org/10.18632/agin
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Glycation Reduction and Aging, a Clinical Evaluation (GRACE) CLOSED Sugar-stress-lowering supplement for postmenopausal women #### GRACE STUDY ###### RECRUITING IS CLOSED Glycation stress is something
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Issues | The Journals of Gerontology: Series B | The Journals of Gerontology: Series B Volume 81, Issue Supplement_1, February 2026 Harmonization Recommendations from the Gateway to Global Aging Data
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Expert reviews rank fisetin and quercetin as top senolytics, with spermidine and resveratrol as supporting players in longevity supplement stacks. ... A comprehensive review of popular longevity suppl
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The goal of our analysis was to test the hypothesis that vitamin D supplementation, omega-3 supplementation and a simple home exercise program (SHEP), individually and in combination, would slow biolo
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# ReviewThe impact of dietary protein intake on longevity and metabolic health ## Keywords
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News/July 16, 2026 # Randomized trial shows spermidine enhances antibody levels in older adults receiving COVID-19 vaccination — Evidence Review Published in Aging Cell, by researchers from Max Delbrü
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## Collagen Peptides and Cellular Aging ClinicalTrials.gov ID ** NCT07456449 Sponsor ** University of Vienna ... Last Update Posted ** 2026-05-05 ... The goal of this clinical trial is to learn if dai
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**BUFFALO, NY — April 21, 2025 — ** A new research paper was published in *Aging (Aging-US) * Volume 17, Issue 3, on March 14, 2025, titled “Effects of a natural ingredients-based intervention targeti
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A groundbreaking randomised controlled trial (RCT) published in *Nature Medicine* on March 9, 2026, reveals that daily multivitamin-multimineral (MVM) supplementation can modestly slow the ticking of
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A new 2026 *Cell Metabolism* study by Maura Fanti and colleagues gives the longevity-diet debate a more precise target than “eat less protein.” In aged mice, the group tested a low-amino-acid pattern
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Volume 81, Issue 8 August 2026 Cover image ... #### THE JOURNAL OF GERONTOLOGY: Biological Sciences ... ##### Effect of inactivation of the USP19 deubiquitinase gene in mice on important phenotypes of
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A landmark 2026 longitudinal cohort study published in *Nature Metabolism* has provided the most robust clinical evidence to date that the age-related decline in **mitochondrial oxidative phosphorylat
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### 2026, Volume 81, Issue Supplement_1 - **1-3 Introduction: Harmonization Recommendations from the Gateway to Global Aging Data** *by* Jinkook Lee & Jere R Behrman - **4-6 NIA perspective on harmoni
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The Lancet Healthy Longevity•June 30, 2026•Blossom C M Stephan, Jennifer Dunne, Jacob Brain, Leanne Greene, Serena Sabatini, Amanda Eddy-Lacey, Bronwyn Myers, Tanya Buchanan, Katherine Ride, James C V
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DUBAI, 5th February, 2026 (WAM) -- Ageing could soon be treated as a medical condition rather than an inevitable part of life, with scientists moving closer to reversing the biological clock, accordin
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Aging Cell. 2026 Feb;25(2):e70371. doi: 10.1111/acel.70371. ... - DOI: 10.1111/acel.70371 ... Aging is a multifactorial process influenced by genetic, environmental, and metabolic factors. Dysregulate
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Volume 81 Issue 4 | The Journals of Gerontology: Series B | Oxford Academic Volume 81, Issue 4 April 2026 Cover image EISSN 1758-5368 ... # Volume 81, Issue 4, April 2026 #### THE JOURNALS OF GERONTO
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# Best USP Verified Last updated: Jun 2, 2026 ... Jun 2, 2026 Updated ... Dr. Berg Maximum Strength 7-in-1 Vitamin D3 K2 10,000 IU | Naturally Derived D3 | 4X Lab-Tested & Verified | High Absorption F
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The U.S. Pharmacopeia (USP) has been named a participating certifier in Amazon's new Compliance Fast-Track Program for dietary supplements. This recognition means products bearing the USP Verified Mar
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- Diet: A whole-food, minimally processed, plant-based diet, high in complex carbohydrates and low in harmful fats and refined sugars.
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In this clip from a FoundMyFitness Premium Member Q&A episode, Rhonda updates listeners on her current supplement routine. ... - Her preferred supplement brands & dosing - What time of day she takes e
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# Great HealthWorks' OmegaXL Sport Earns Prestigious NSF Certified for Sport® Designation *OmegaXL Sport verified free of 290+ banned substances, achieving the gold standard in athletic safety and joi
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Last updated on 21 Apr, 2026 Examine helps you understand what the research says about nutrition, supplements, and health — clearly and without bias from ads, sponsors, or partnerships.
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A common concept here is a ‘barbell strategy’, where we make sure early trials are robust on safety, then grant accelerated approval based on reasonable evidence, followed by rigorous enforcement of c
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This interactive database depicts the status of the most significant clinical trials of longevity-related therapies.
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NSF’s Certified for Sport® testing program helps confirm that sports supplements and sports nutritional products do not contain substances banned by many major athletic organizations. ... This indepen
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We tested 17 fish oil, krill oil, and algal oil supplements for omega-3s, heavy metals, and freshness. One product failed freshness testing. Fish Oil, Krill Oil, and Algal Oil Omega-3 Supplements Revi
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#### GSA 2026 in National Harbor, MD Join your colleagues at the premier Annual Scientific Meeting for fields related to gerontology. ... #### Free registration with booth purchase! Reserve your 2026
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## GSA 2026 Scientific Meeting November 4 - 7 | National Harbor, MD. Visit gsa2026.org ### Important Updates **Late Breaking Abstracts**—Now Open | July 7 - August 13 **Now Open— ** Register | Book Yo
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The 13^th^ Aging Research & Drug Discovery (ARDD) Meeting, the world's largest conference dedicated to longevity biotechnology, will take place from October 1-3, 2026, at the David Rubenstein Treehous
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**04-21-2026** “*The 12th Aging Research and Drug Discovery (ARDD) meeting convened at the University of Copenhagen, presenting a comprehensive overview of recent advancements in the biology of aging*
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## GSA 2026 Scientific Meeting November 4 - 7 | National Harbor, MD. Visit gsa2026.org ### Important Updates **Late Breaking Abstracts**—Now Open | July 7 - August 13
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# Aging Research and Drug Discovery Meeting 2026 Copenhagen (København) (ARDD 2026) ... **The 13th Aging Research and Drug Discovery Meeting 2026 (ARDD 2026) will take place in late August / early Sep
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1985 New York NY USA ... Promote biomedical *aging* studies directed towards increasing the functional life span of humans; keep the public informed of the progress of aging research and of practical
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Last updated: April 24, 2026 Sponsor: Brigham and Women's Hospital Overall Status: Completed #### Phase N/A #### Condition Body Composition Bone Density #### Treatment Vitamin D3 placebo omega-3 fatty
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# Nicotinamide Riboside and Pterostilbene for Improving Cytopenia and Delaying Disease Progression in Patients with Clonal Cytopenia of Undetermined Significance or Myelodysplastic Syndrome, ROSS Tria
# U of A Launches Rapamycin Clinical Trial with Philanthropic Support of Alumnus Ken Coit April 1, 2026 Researchers at the University of Arizona R. Ken Coit College of Pharmacy will begin a double-bli
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# Thorne's Quercetin Phytosome Trial for Metabolic Health Was Terminated Early A sponsored 90-day trial of enhanced-absorption quercetin targeting cholesterol, blood sugar, and metabolic age was termi
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The official web resource of the TAME Trial, managed by the American Federation for Aging Research. ... #### The Targeting Aging with Metformin (TAME) Trial is a series of nationwide, six-year clinica
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The POLYCAD (POLYamine CArdiovascular Disease) trial is an ongoing randomized controlled trial testing spermidine supplementation in older adults with established coronary artery disease (CAD). The tr
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***From cellular recycling to cognitive aging, spermidine is drawing scientific interest, but the evidence needed for routine human use is still emerging.** * ... In a recent 'Article in Press' review
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Based on a randomized controlled trial of berberine (registered in ClinicalTrials.gov on Dec 2018, NCT03770325), leveraging proteomics and sex hormones data, we built a signature reflecting response t
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In a pre-specified ancillary study of the VITaminD and omegA-3 (VITAL) trial, we examined the effect of 1 g of marine omega-3 FA per day, comprised of 460 mg eicosapentanoic acid and 380 mg of docosah
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# ReviewEffect of Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Outcomes in Patients with Diabetes: A Meta-analysis of Randomized Controlled Trials ## Keywords
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# ReviewA systematic review and meta-analysis of randomized controlled trials on the effects of magnesium supplementation on insulin sensitivity and glucose control ## Graphical abstract
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This research marks the initial exploration into the safety of a new high-p spermid trihydroide supplement (hpSPD) for human use. ... In this randomized, double-blind, placebo-controlled trial, 37 hea
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# A Randomized Controlled Trial of Long-Term ( *R*)-α-Lipoic Acid Supplementation Promotes Weight Loss in Overweight or Obese Adults without Altering Baseline Elevated Plasma Triglyceride Concentratio
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## RBR-78bcfbc Effect of Curcumin on gut health and inflammatory aspects in Overweight and Obese individuals Date of registration: 07/08/2026 ^(mm/dd/yyyy)^ Last approval date : 07/08/2026 ^(mm/dd/yyy
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## RBR-2b7hw6b Impact of Resveratrol on the health of individuals with type 2 Diabetes Date of registration: 06/06/2026 ^(mm/dd/yyyy)^ Last approval date : 06/06/2026 ^(mm/dd/yyyy)^ ### Study type: In
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## Palvella Therapeutics Announces First Patients Dosed in Phase 2 LOTU Trial of Fast Track-Designated QTORIN™ Rapamycin for Clinically Significant Angiokeratomas May 4, 2026 ... *Phase 2 single-arm,
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# Harvard Study: NMN Shows 18% Improvement in VO2 Max for Older Adults First large-scale NMN trial (N=240) shows significant aerobic capacity improvements in adults 60+. Published in Cell Metabolism.
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We report results from the largest randomized, double-blind, placebo-controlled trial of nicotinamide mononucleotide (NMN) supplementation to date. Over 12 months, participants receiving 500 mg/day NM
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## A Clinical Trial to Assess the Absorption, Safety, and Efficacy of an Oral Nicotinamide Adenine Dinucleotide (NAD+) Supplement in Healthy Adults ClinicalTrials.gov ID ** NCT07692633 Sponsor ** Reus
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## Assessment of the Effects and Safety of Spermidine Supplementation on Blood Lipids and Body Weight in Overweight or Obese Individuals With Hyperlipidemia ClinicalTrials.gov ID ** NCT07662330 Sponso
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## Phase II, Randomized, Double-blind, Placebo-controlled Clinical Trial to Evaluate the Efficacy and Safety of Omega-3 Fatty Acids as an Adjunct to Morphine in Acute Postoperative Pain (O3MORPH) Clin
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## Nicotinamide Riboside, Vit B3 Analogue, and Brain Energy Metabolism ClinicalTrials.gov ID ** NCT07649161 Sponsor ** Massachusetts General Hospital Information provided by ** MOHAMED, SOLIMAN, Massa
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## Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients (ALA-MYO-PCOS) ClinicalTrials.gov ID ** NCT07630779 Sponsor ** Beni-Suef University Information provided by **
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Not yet recruiting** ## Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial) (ROSS) ClinicalTrials.gov ID ** NCT07579429 Sponsor ** University of Colorado, Denver Information provi
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## Alpha-Lipoic Acid in Mitigating Cisplatin-Induced Nephrotoxicity ClinicalTrials.gov ID ** NCT07564479 Sponsor ** Minia University Information provided by ** Asmaa Bassem Mohammed, Minia University
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Not yet recruiting** ## Effects of Berberine on Cardiometabolic Outcomes ClinicalTrials.gov ID ** NCT07541898 Sponsor ** University of Central Lancashire Information provided by ** Jonathan Sinclair,
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Completed** ## Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men (HIITCRECOG) ClinicalTrials.gov ID ** NCT07534293 Sponsor ** U
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Completed** ## Effect of Curcumin Add-On Therapy on Quality of Life and IL-1β Levels in Patients With Schizophrenia (CUR-SCZ) ClinicalTrials.gov ID ** NCT07523256 Sponsor ** Rinvil Renaldi ... Last Up
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Completed** ## Magnesium Supplementation With Fluoxetine for Cognitive Function in Depression (MAG-DEP) ClinicalTrials.gov ID ** NCT07521358 Sponsor ** Hasanuddin University Information provided by **
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## Short-Term Safety of Low-Dose Creatine Hydrochloride: A 28-Day Single-Arm Pilot Study ClinicalTrials.gov ID ** NCT07521059 Sponsor ** Vireo Systems, Inc. ... Last Update Posted ** 2026-04-09 **Comp
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Not yet recruiting** ## Can People Achieve a Target Omega-3 Index by Following a Personalized Omega-3 Dosing Regimen? ClinicalTrials.gov ID ** NCT07480707 Sponsor ** Fatty Acid Research Institute ...
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Active, not recruiting** ## Combination Gerotherapeutic Interventions for Healthspan Improvement ClinicalTrials.gov ID ** NCT07475546 Sponsor ** AgelessRx ... Last Update Posted ** 2026-03-16 Study De
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## Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat ClinicalTrials.gov ID ** NCT07472426 Sponsor ** University of Northern Iowa I
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## Study on the Efficacy of Quercetin Intake in Patients With Fibrotic Interstitial Lung Diseases. ClinicalTrials.gov ID ** NCT07466420 Sponsor ** Katerina M. Antoniou ... Last Update Posted ** 2026-0
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Not yet recruiting** ## Berberine Phytosome for Signs and Symptoms of Polycystic Ovary Syndrome (PCOS) ClinicalTrials.gov ID ** NCT07465575 Sponsor ** Liaquat University of Medical & Health Sciences I
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Not yet recruiting** ## Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease C
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## Evaluation of the Pharmacokinetics of Curcumin Capsules in Healthy HumanClinicalTrials.gov ID ## Study Overview Main objective: Through blood drug concentration testing, evaluate the post-meal phar
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## Influence of the Urolithin A on the Population With BMI Higher Than 30 During Restricted Eating. (Obesity UroA) ClinicalTrials.gov ID ** NCT07377136 Sponsor ** Charles University, Czech Republic In
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## Supplementation With Sirtuin Activators in Women With Increased Body WeightClinicalTrials.gov ID ## Study Overview The goal of this clinical trial is to learn if the six-month supplementation with
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## 12-week Magnesium Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-beingClinicalTrials.gov ID ## Study Overview ... One supplement that has received a lot of att
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## The Effect of Urolithin A (Mitopure®) Supplementation on Muscle Strength in Healthy Middle-Aged Adults (ATLAS 2)ClinicalTrials.gov ID ## Study Overview Dietary Supplement: Placebo Dietary Supplemen
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## Iterative Design Trial to Assess Dietary Supplements and Other Aging-targeted TherapiesClinicalTrials.gov ID ... This is a multi-cohort, open-label, adaptive trial designed to evaluate the safety,
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## Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults ClinicalTrials.gov ID ** NCT07144527 Sponsor ** Scott Silveira ... Last Update Posted ** 2026-
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Recruiting soon # Omega-3 Fatty Acid Supplementation for Adult and Juvenile Dermatomyositis What is being tested ## FISH OIL 500MG OMEGA-3 SOFT GEL MINIS + Placebo Dietary Supplement Who is being recr
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## Study of High-Dose Resveratrol in Patients With Stable Ischemic Heart DiseaseClinicalTrials.gov ID ## Study Overview Dietary Supplement: High-dose resveratrol 500 mg/day Other: Placebo - SW028 ## C
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## Intervention of Nicotinamide Mononucleotide in Middle-aged and Elderly People (NMNAGING) ClinicalTrials.gov ID ** NCT06592859 Sponsor ** People's Hospital of Quzhou Information provided by ** Feng
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## Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With MultimorbidityClinicalTrials.gov ID ... We will conduct a clinical trial in healthy volunteers and older patients with multiple
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# FIRST Fisetin to Reduce Senescence and Mobility Impairment in Peripheral Artery Disease: the FIRST Pilot Randomized Trial Qué se está evaluando ... ## Estudio de Tratamiento Controlado con PlaceboFa
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## Effects of Urolithin A Supplementation on Glucose Metabolism in Healthy Adults 55 >= Years Old: A Randomized Triple-Masked Controlled Clinical TrialClinicalTrials.gov ID ## Study Overview ... Uroli
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## Low Dose Rapamycin in ME/CFS, Long-COVID, and Other Infection Associated Chronic ConditionsClinicalTrials.gov ID ## Study Overview The goal of this observational study is to assess the clinical res
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## The NADage Study: Nicotinamide Riboside Replenishment Therapy Against Functional Decline in Aging (NADage)ClinicalTrials.gov ID ## Study Overview This clinical study, designed as a double-blind, ra
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Recruiting Phase 1 Phase 2 ## Fisetin Fisetin to Improve Vascular Function in Older Adults Sponsor: University of Colorado, Boulder Code: NCT06133634 Conditions Aging Endothelial Dysfunction Arterial
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## Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative NeoplasmsClinicalTrials.gov I
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Active, not recruiting** ## Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure ClinicalTrials.gov ID ** NCT05690464 Sponsor ** Brigham and Women's Hospital ... The purpose of this
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## The Effect of NAD Supplementation on Brain Vascular Health in AgingClinicalTrials.gov ID ## Study Overview Drug: Nicotinamide riboside Drug: Placebo - 14782 ## Contacts and Locations ... **Name: **
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Active Not Recruiting NA INTERVENTIONAL 2-arm NCT04562831 # The NO-ALS Study: A Trial of Nicotinamide/Pterostilbene Supplement in ALS. A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbe
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## Taurine Supplementation and Training Effects on Energy Metabolism, Inflammation and Oxidative Stress in Obese Women (Taurine)ClinicalTrials.gov ID ## Study Overview A double-blind placebo-controlle
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## Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active SurveillanceClinicalTrials.gov ID ## Study Overview ... Curcumin is a widely studied nutraceutical that was first d
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## Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Adults (AFFIRM-LITE)ClinicalTrials.gov ID ## Study Overview Dietary Supplement: Fisetin Drug: Placebo oral capsule - 1
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## Omega-3 Fatty Acid in Treating Patients With Stage I-III Breast CancerClinicalTrials.gov ID ## Study Overview PRIMARY OBJECTIVES: I. To determine if omega-3 dietary supplementation (omega-3 fatty a
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# Metformin Shows Promise for Slowing Cellular Aging in Prediabetic Adults Six-month trial examines whether metformin treatment can improve telomere length and longevity gene expression in prediabetic
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*Investigational Oral Candidate JOTROL* ^*™* ^* Addresses a Parkinson’s Disease Market with No Current Disease-modifying Therapies Available* **Jupiter, FL, May 27, 2026 (GLOBE NEWSWIRE) -- ** Jupiter
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|最近我々は、マウスを用いた動物試験により、レスベラトロール類の一つであるプテロスチルベンが、高齢卵子で減少している抗老化遺伝子SIRTの発現を増加させ、エイジングにより低下したミトコンドリア機能を向上させ、その結果妊娠率が改善することを見出した（特願：2016-187572, PCT/JP2017/34361）。そこで本研究では、動物試験においてエイジング卵子の質の改善に対する有用性を確認したサ
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Homa Shalchi 713-798-4710 Houston, TX ... A randomized, double blind human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC – a combinatio
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Emerging Subjective sleep quality in adults with self-reported poor sleep EmergingClinical Metabolic markers (glucose, insulin sensitivity, HbA1c) in diabetic populations EmergingClinical Ageing hallm
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Front. Nutr., 21 July 2026 Sec. ... Volume 13 - 2026 | https://doi.org/10.3389/fnut.2026.1834344 … ... Urolithin A (UA), a gut microbiota–derived metabolite, has been proposed to improve skeletal musc
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List updated May 14, 2025 ### Nicotinamide Riboside for Veterans (NR-VETS) This trial examines nicotinamide riboside (NR), a form of vitamin B3, for its potential to improve physical and cognitive per
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|Unique ID issued by UMIN|UMIN000062041| ... |Receipt number|R000070989| |Scientific Title|Single-ingredient Vitamin D3 3200 IU versus Vitamin D3 3200 IU/Zinc/Quercetin Supplementation in Adult Indone
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- ### FDA Greenlights Life Biosciences’ Human Study, Setting Up Pivotal Test for Aging Theory from Harvard’s David Sinclair Jan 30, 2026 - ### A Natural Senolytic Supplement Curbs Heart Aging in New C
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# NCT07657390 Nicotinamide riboside/Pterostilbene Cancer Pain Clinical Landscape Report 2026: Design, Endpoints, Sponsor and Readout Outlook 4 August 2026 ... *MCP evidence snapshot: 4 August 2026. Tr
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# ChiCTR2600123561 Nicotinamide riboside/Pterostilbene Adult Acute Myeloblastic Leukemia Clinical Landscape Report 2026: Design, Endpoints, Sponsor and Readout Outlook 24 July 2026 ... *MCP evidence s
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# Assessing the Safety and Tolerability of NMN in DHDDS-CDG ## ID#: NCT07572825 ## Age: 4 years - 66+ ## Gender: All ## Healthy Subjects: No ## Study Phase: Phase 1 ## Recruitment Status: Recruiting #
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Project Details # TauAge randomised, controlled pilot trial: Does taurine supplementation with 4 g/day for 6 months slow human ageing? Subject Area Biogerontology and Geriatric Medicine Term since 202
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**Objectives**: Conduct a randomized double-blind placebo-controlled crossover pilot trial on adults with nonclinical insomnia symptoms to examine the effectiveness of magnesium supplementation on sle
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Status: Enrolling # Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial Phase II Age ≥18 Sponsor National Cancer Institu
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Schwarz C, Benson GS, Horn N, et al. Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial. JAMA Netw Open. 2
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Importance: Preclinical and human observational studies suggest that metformin may decrease age-related pathology, including frailty. Objective: Determine whether metformin reduces frailty progression
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A new meta-analysis led by researchers from the Fatty Acid Research Institute (FARI) provides the clearest picture to date of the relationship between omega-3 fatty acid supplementation and atrial fib
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Explor Endocr Metab Dis. 2026;3:101470 **DOI:** https://doi.org/10.37349/eemd.2026.101470 … ... A randomized controlled trial revealed that 24 weeks of supplementation of RSV resulted in a significant
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- # Tuna Meat Enhances Mitochondrial Function and Antioxidant Capacity via Nicotinamide Adenine Dinucleotide-Sirtuin Activation in Humans: A Clinical Trial Study ... - **Source:** Current Nutrition &
# Low-dose oral nicotinamide mononucleotide for immune thrombocytopenia: a phase 1/2 trial Nat Med. 2026 Jun;32(6):2026-2036. doi: 10.1038/s41591-026-04366-x. Epub 2026 Apr 29. ... Based on these find
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**Open Call for available White Space in the CECAD Research Center** **The CECAD Excellence Cluster on Aging and Aging-associated Diseases seeks independently funded research groups to join and suppor
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# San Antonio's Barshop Institute to test three approved drugs for slowing aging ... At UT Health San Antonio’s Sam and Ann Barshop Institute, researchers are preparing a major new test of an old scie
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Publicerad: 2026-04-23 11:12 | Uppdaterad: 2026-04-23 15:12 ... Verksamhetsrapporten 2023–2025 ger en översikt av Aging Research Center (ARC):s tvärvetenskapliga forskning om hjärnans åldrande, demens
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NIA Intervention Testing Program (ITP) Announces Annual Call for Compounds to Test for Lifespan Extension in Mice Notice Number: NOT-AG-25-014 ## Key Dates Release Date: February 18, 2026 ## Related
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Congratulations to Professor Miles Witham, co-lead of the AGE Research Group, who has been appointed as a Senior Investigator by the National Institute for Health and Care Research (NIHR).
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A new editorial was published in Volume 18 of *Aging-US* on May 18, 2026, titled "Public health in the age of longevity interventions: from prevention to system-wide resilience." The editorial was aut
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### The killifish reveals in fast-forward what takes decades in humans: chronic inflammation, DNA damage in precursor cells and remodelling processes in the blood-forming organ characterise the ageing
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06/22/2026 · News · Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut · Lebenswissenschaften · Forschungsergebnis A review article now published in “Nature Reviews Genetics” brings togeth
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The Interventions Testing Program (ITP) is a peer-reviewed program designed to identify agents that extend lifespan and healthspan in mice. Investigators at any university, institute, company, or othe
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The IHA is a centre of excellence for research on the biology of ageing and ageing related diseases. ... Upcoming Events 06 Nov in person Understanding evolution through game theory: Insights from stu
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Published: 20-11-2025 15:04 | Updated: 08-12-2025 08:50
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**Healthy Ageing Symposium: living better for longer** Bringing together academics, industry leaders and charity representatives, the event aimed to address the challenges of ageing healthily. In part
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# Half-time seminars Half-time Seminar: Franziska Steffens 27-08-2026 9:30 am - 12:00 pm Add to iCal Campus Solna Karolina lecture hall, Widerströmska huset, Tomtebodavägen 18a, Solna "Old-age depress
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A robot in the living room: Domesticating a robotic personal trainer in very old age Gerontechnology, 2026 The domestication theory explains how individuals integrate new technologies into their daily
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Home Events Public Events Scientific Events All Events Upcoming Lectures and Events Cologne Seminars on Ageing "Uncovering Hidden Diseases: Genotype-First Insights into How Ubiquitylation Controls Neu
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We aim to elucidate the molecular, physiological and evolutionary mechanisms underlying ageing. ... ## Events ### #### FOR5762 Seminar: Integrating Mitochondrial Resilience: From Subcellular Stress Si
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Researchers have investigated the role played by the cell membrane lipid phosphatidylcholine in this process — and have identified a potential approach to healthy aging. 05/27/2026 · News · Leibniz-In
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Leyden Academy visits the Aging Research Center (ARC) and TraCeDem at Karolinska Institutet on 21 May 2026. ... On 21 May 2026, a delegation from Leyden Academy on Vitality and Ageing visited the Agin
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Wir erforschen die molekularen, physiologischen und evolutionären Mechanismen des Alterns. ... ## Veranstaltungen ### #### FOR5762 Seminar: Integrating Mitochondrial Resilience: From Subcellular Stres
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# Barshop Institute to receive up to $38 million from ARPA-H, anchoring UT San Antonio as a national leader in aging and healthy longevity science Contact: Steven Lee, (210) 450-3823, lees22@uthscsa.e
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One of the leading longevity clinics specializing in preventive and personalized medicine. Strona · Zdrowie i medycyna Belwederska 9, Warsaw, Poland +48 884 084 040 hello@longevity-center.eu linktr.ee
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**Prof. dr. Cor Calkhoven – Group le** **ader of the Laboratory of Gene regulation in ageing and age-related diseases – ERIBA/UMCG** ... **Topic** Gene regulation in ageing and age-related diseases. W
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Symposium on Aging The 2026 Paul F. Glenn Center for the Biology of Aging Research BLAVATNIK INSTITUTE HARVARD MEDICAL SCHOOL The Paul F. Glenn Center for the Biology of Aging Research Each year the C
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**When & Where: ** **Date: 11th - 14th October 2026** **Venue: MPI for Biology of Ageing & CECAD Research Center, Cologne, Germany** **You can now register for the event in our Registration Tool:** ..
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**When & Where: ** **Date: 14th - 16th October 2026** **Venue: MPI for Biology of Ageing & CECAD Research Center, Cologne, Germany** **Registration portal** will be opened in second half of March! *We
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NIH's National Institute on Aging is seeking proposals for compounds to be tested through the Interventions Testing Program (ITP), which measures the ability to extend lifespan and/or delay the onset
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Glycation stress is something that happens when sugars get stuck to proteins in our body, getting in the way of their normal function. Buck scientists have developed a combination supplement, GLYLO, t
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A major study found that glucosamine, a popular joint supplement, was linked to faster progression from mild cognitive impairment to dementia. Observational finding, not causation, but raises a safety
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An RCT in Hepatology Communications found L-taurine reduced fatigue in decompensated cirrhosis patients. Adds to human RCT evidence for taurine, which gained attention after a 2023 Science paper on ta
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A placebo-controlled trial published in JAMA Network Open found spermidine supplementation improved memory in older adults with subjective cognitive decline. One of the few human RCTs for this compoun
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A Nature Aging review charts the move from first-generation senolytics (dasatinib+quercetin) to precision senotherapeutics. Supplement-grade quercetin and fisetin are first-generation, with known limi
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The largest randomized trial of NMN to date reported significant improvement in cognitive function. Prior trials were small and focused on physical endpoints. Effect size pending peer-reviewed publica
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A Nestle Health Science-led study found 14-day NR+NMN supplementation altered metabolic health markers in ways not previously described. Industry-funded, not yet peer-reviewed.
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A two-year RCT led by Mass General Brigham found that daily multivitamin supplementation slowed biological aging measured by DNA methylation age. One of the first long-duration RCTs using epigenetic c
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A Baylor University trial found GlyNAC (glycine + N-acetylcysteine) reversed 9 of 12 aging hallmarks in older adults. Low-cost combination of two amino acids, not a proprietary compound.
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ConsumerLab tested multivitamins and found 32% failed testing. Failure reasons included incorrect ingredient amounts, contamination, and disintegration problems. Products that failed carried labels cl
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The largest single-cell aging study to date mapped 7 million cells across 21 organs, finding aging proceeds as a synchronized body-wide process. Implications for multi-target supplement strategies.
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To ensure that the process remains within safe limits, the genes responsible for reprogramming will be regulated by a unique genetic switch, activating them solely during the period when patients are
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Issues | The Journals of Gerontology: Series B | The Journals of Gerontology: Series B Volume 81, Issue Supplement_1, February 2026 Harmonization Recommendations from the Gateway to Global Aging Data
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Expert reviews rank fisetin and quercetin as top senolytics, with spermidine and resveratrol as supporting players in longevity supplement stacks. ... A comprehensive review of popular longevity suppl
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The goal of our analysis was to test the hypothesis that vitamin D supplementation, omega-3 supplementation and a simple home exercise program (SHEP), individually and in combination, would slow biolo
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# ReviewThe impact of dietary protein intake on longevity and metabolic health ## Keywords
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# Rejuvenation Roundup March 2026 ... ## Research Roundup **Novel Mechanism for Parkinson’s Is Linked to ATP Deficiency**: Scientists have discovered that ATP deficiency disrupts dopamine processing i
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Discover June 2026’s major rejuvenation breakthroughs from genomic interventions to the Thalion Initiative reshaping how we combat biological aging. 73% reduction in epigenetic age markers Recent geno
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# Rejuvenation Roundup July 2026 ... The fight for longevity treatments that measurably improve and lengthen quality of life is ongoing in research, treatment, and policy, with promising successes and
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# REJUVANT OUTPERFORMS ALL TESTED SUPPLEMENTS, INCLUDING STANDARD AKG AND NAD+ IN LANDMARK AGING CELL STUDY FERNANDINA BEACH, Fla., May 28, 2026 /PRNewswire/ -- Ponce De Leon Health (PDLH), a commerci
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editorial eBioMedicine. 2026 Feb 11;124:106175. doi: 10.1016/j.ebiom.2026.106175 # Epigenetic clocks: advancing biological age measures towards meaningful clinical use eBioMedicine Collection date 202
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## Collagen Peptides and Cellular Aging ClinicalTrials.gov ID ** NCT07456449 Sponsor ** University of Vienna ... Last Update Posted ** 2026-05-05 ... The goal of this clinical trial is to learn if dai
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**BUFFALO, NY — April 21, 2025 — ** A new research paper was published in *Aging (Aging-US) * Volume 17, Issue 3, on March 14, 2025, titled “Effects of a natural ingredients-based intervention targeti
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A groundbreaking randomised controlled trial (RCT) published in *Nature Medicine* on March 9, 2026, reveals that daily multivitamin-multimineral (MVM) supplementation can modestly slow the ticking of
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A new 2026 *Cell Metabolism* study by Maura Fanti and colleagues gives the longevity-diet debate a more precise target than “eat less protein.” In aged mice, the group tested a low-amino-acid pattern
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Live registry of ongoing human clinical trials for the supplements covered in our protocol pages — pulled from ClinicalTrials.gov. Last updated: March 2026 ⚠️ Clinical trials listed here are for infor
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**Biomarkers of Neurodegeneration**: The latest joint Series from *eBioMedicine*and *The Lancet Healthy Longevity*seeks to highlight the roles of biomarkers of neurodegeneration in a multitude of cont
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A landmark 2026 longitudinal cohort study published in *Nature Metabolism* has provided the most robust clinical evidence to date that the age-related decline in **mitochondrial oxidative phosphorylat
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Aging Cell. 2026 Feb;25(2):e70371. doi: 10.1111/acel.70371. ... - DOI: 10.1111/acel.70371 ... Aging is a multifactorial process influenced by genetic, environmental, and metabolic factors. Dysregulate
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Many researchers now assert that mastering the art of cellular rejuvenation could be pivotal in changing the duration and quality of human life. Some are optimistic that they could eventually leverage
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The Journals of Gerontology: Series A | Oxford Academic Latest Issue Volume 81 Issue 8 August 2026 #### Editors-in-Chief ... This new section of the journal brings the opportunity for all disciplines
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There are dozens of compounds with some claim to "longevity ingredient" status. Most have thin evidence; a few have substantial published human or animal RCT bases. This article covers the five with t
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July 22, 2026 ... - The latest findings bolster the expanding case for gerotherapeutics, particularly those focused on blood cells, which can affect multiple organs system-wide. Novel agents are curre
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DUBAI, 5th February, 2026 (WAM) -- Ageing could soon be treated as a medical condition rather than an inevitable part of life, with scientists moving closer to reversing the biological clock, accordin
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Volume 81 Issue 7 | The Journals of Gerontology: Series A | Oxford Academic Volume 81, Issue 7 July 2026 Cover image ... ##### Effects of a short-term multicomponent functional exercise program on th
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Lancet Healthy Longev. 2026 May 21:100865. doi: 10.1016/j.lanhl.2026.100865. Online ahead of print. ... The Lancet Healthy Longevity - PMID: 42167301 - DOI: 10.1016/j.lanhl.2026.100865 *No abstract av
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Volume 81 Issue 4 | The Journals of Gerontology: Series B | Oxford Academic Volume 81, Issue 4 April 2026 Cover image EISSN 1758-5368 ... # Volume 81, Issue 4, April 2026 #### THE JOURNALS OF GERONTO
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### The Journals of Gerontology: Psychological Sciences & Social Sciences Volume 81, Issue Supplement_1, February 2026 For the **Table of Contents** to the latest issue of ***The Journals of Gerontolo
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- Her preferred supplement brands & dosing
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## USA Brands |NMN Product|Approx. price per gram|3rd Party Analysis Certificate?| |--|--|--| |Capsules| | | |Renue NMN - 125 mg capsules|$2.30/gram ($69 / 30g) + 10% off coupon code|Summit Laboratory
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Last updated on 21 Apr, 2026 Examine helps you understand what the research says about nutrition, supplements, and health — clearly and without bias from ads, sponsors, or partnerships. ... Compare su
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Both ship as liposomal liquids in single-serve packets. Neither has been independently compared head-to-head, so picking between them is a question of price, taste, and which subscription a reader pre
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Examine analyzes and summarizes research to determine which supplements and non-pharmaceutical interventions work. ... **See what the evidence shows.** Information on Examine is organized into 26 heal
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- **We want *trans*-resveratrol**, not *cis*-resveratrol. From David’s studies, cis-Resveratrol did not activate the sirtuin enzyme, but trans-Resveratrol did. - **We want 98% or greater purity.** Dav
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We tested 17 fish oil, krill oil, and algal oil supplements for omega-3s, heavy metals, and freshness. One product failed freshness testing. Fish Oil, Krill Oil, and Algal Oil Omega-3 Supplements Revi
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We analysed discussion threads across r/Supplements, r/Biohackers, r/Longevity, and chronic-fatigue communities to understand what *actual users* experience. What follows is a synthesis of real-world
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Compared with other precursors, the side effects of NA are well known. The most common adverse effects of NA include flushing, rash, hyperglycemia, hyperuricemia, and gastrointestinal disorders. Addit
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The Federal Trade Commission took action today against a marketer of vitamins and other supplements called The Bountiful Company (Bountiful) for abusing a feature of Amazon.com to deceive consumers in
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Bountiful Co., a company specializing in nutritional supplements, has agreed to pay $600,000 in response to allegations from the Federal Trade Commission (FTC). The FTC accused the company of misrepre
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# Amazon review: Be cautious with your health supplement orders at Amazon Canada J ... Jul 29, 2026 3:04 pm UTC ... I purchased 2 bottles of ONE A DAY 250 tablet complete multivitamin bottles for myse
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In a first-of-its-kind case, the US Federal Trade Commission has taken action on the scourge of Amazon sellers who pay for phony reviews. The complaint, which seeks a $12.8m settlement, alleges a shad
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The online giant expanded its verification rules beyond high-risk categories, requiring approved auditors to validate FDCA compliance for every product listing. ... As of January 2026, Amazon is requi
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#### Submissions - Workshop Applications CLOSED - Abstract Submissions CLOSED - Reviewer Submissions CLOSED #### Other Key Dates - Abstract Acceptance/Non-Acceptance Notifications—May 26 - Late Breaki
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#### GSA 2026 in National Harbor, MD Join your colleagues at the premier Annual Scientific Meeting for fields related to gerontology. ... #### Free registration with booth purchase! Reserve your 2026
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## THE LONGEVITY SUMMIT 2026 THE FUTURE OF MEDICINE: ELIMINATING DISEASES OF AGING December 9-10 | Buck Institute for Research on Aging Novato, CA ## LEARN FROM YOUR PEERS Welcome to The Longevity Sum
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The official website for the Longevity Summit Dublin 2026, a premier science-led. ... - Speaker Onboarding — The official website for the Longevity Summit Dublin 2026, a premier science-led conference
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The 13^th^ Aging Research & Drug Discovery (ARDD) Meeting, the world's largest conference dedicated to longevity biotechnology, will take place from October 1-3, 2026, at the David Rubenstein Treehous
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**04-21-2026** “*The 12th Aging Research and Drug Discovery (ARDD) meeting convened at the University of Copenhagen, presenting a comprehensive overview of recent advancements in the biology of aging*
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ROME · MAY 25-26 2026 # The event for integral and sustainable aging ROME · MAY 25-26 2026 ... **In the heart of Rome, the Eternal City,** where millennia of history meet reflection on the destiny of
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## GSA 2026 Scientific Meeting November 4 - 7 | National Harbor, MD. Visit gsa2026.org ### Important Updates **Submissions Open**—Late Breaking Abstracts July 7-August 13 **Now Open— ** Register | Boo
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**Gerontological Society of America** 1101 14th Street NW, Suite 1220 Washington, DC 20005 United States Phone: (202) 842-1275 Email: membership@geron.org © Gerontological Society of America 2024 and
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# Agenda Subject to minor changes **Thursday, June 4th, 2026** |8:15 am|Coffee & Networking| |--|--| |9:00 am|Longevity Global IntroductionWelcome and Overview of the summit’s mission| ** – Why we nee
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# Aging Research and Drug Discovery Meeting 2026 Copenhagen (København) (ARDD 2026) ... **The 13th Aging Research and Drug Discovery Meeting 2026 (ARDD 2026) will take place in late August / early Sep
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# Agenda Subject to minor changes **Tuesday, May 26, 2026** |8:15 am|Coffee & Networking| |--|--| |9:00 am|Welcome and Overview of the summit’s mission Christin Glorioso, MD, PhD (Longevity Global)| *
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Last updated: April 24, 2026 Sponsor: Brigham and Women's Hospital Overall Status: Completed #### Phase N/A #### Condition Body Composition Bone Density #### Treatment Vitamin D3 placebo omega-3 fatty
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# Nicotinamide Riboside and Pterostilbene for Improving Cytopenia and Delaying Disease Progression in Patients with Clonal Cytopenia of Undetermined Significance or Myelodysplastic Syndrome, ROSS Tria
Contact: Eileen Teves, 210-450-7239, tevese@uthscsa.edu Content provided by Claire Kowalick **SAN ANTONIO, March 25, 2026** – **UT Health San Antonio**, the academic health center of **The University
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# U of A Launches Rapamycin Clinical Trial with Philanthropic Support of Alumnus Ken Coit April 1, 2026 Researchers at the University of Arizona R. Ken Coit College of Pharmacy will begin a double-bli
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The present study aimed to determine safety and tolerability of spermidine supplementation in mice and older adults. ... In the human cohort, a randomized, placebo-controlled, double-blind Phase II st
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The Targeting Aging with Metformin trial is the most significant longevity trial currently running. Here is the current enrollment status, timeline, and what interim signals look like. ... The Targeti
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Cell Res. 2026 Jan 5;36(1):11–37. doi: 10.1038/s41422-025-01203-7 # Table 2. Clinical trials of Spermidine. |Trial ID|Eligibility|Study Focus|Trial status / Key Findings| |--|--|--|--| |NCT06017219|Ma
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Cell Res. 2026 Jan 5;36(1):11–37. doi: 10.1038/s41422-025-01203-7 # Table 1. Clinical trials of Urolithin A. |Trial ID|Eligibility|Study Focus|Trial status/Key Findings| |--|--|--|--| |NCT02655393|Adu
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#### Phase #### Condition Osteoporosis #### Treatment Quercetin 1.250 mg (oral) Dasatinib 100 Mg Oral Tablet Nicotinamide Riboside 1g (oral) ... Ages 60-90 All Genders ... This randomised clinical tri
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In 2023, Unity Biotechnology’s lead senolytic candidate **UBX1325** — a BCL-xL inhibitor targeting senescent cells in the eye — failed to meet its primary endpoint in a Phase 2 trial for wet age-relat
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Based on a randomized controlled trial of berberine (registered in ClinicalTrials.gov on Dec 2018, NCT03770325), leveraging proteomics and sex hormones data, we built a signature reflecting response t
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The present study was designed as a randomized, double-blind, placebo-controlled proof-of-concept trial to investigate the effect of short-term (4 weeks) UA supplementation on immune health and system
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In a pre-specified ancillary study of the VITaminD and omegA-3 (VITAL) trial, we examined the effect of 1 g of marine omega-3 FA per day, comprised of 460 mg eicosapentanoic acid and 380 mg of docosah
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Early 'first-generation' senolytics, including navitoclax (ABT-263) and the dasatinib–quercetin (D + Q) combination, provided proof-of-concept that selective removal of SnCs can alleviate certain fibr
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However, the optimal dose of NR remains unknown, and doses exceeding 2000 mg daily have not been tested in humans. To evaluate the safety of high-dose NR therapy, we conducted a single-center, randomi
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# ReviewEffect of Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Outcomes in Patients with Diabetes: A Meta-analysis of Randomized Controlled Trials ## Keywords
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This research marks the initial exploration into the safety of a new high-p spermid trihydroide supplement (hpSPD) for human use. ... In this randomized, double-blind, placebo-controlled trial, 37 hea
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## RBR-78bcfbc Effect of Curcumin on gut health and inflammatory aspects in Overweight and Obese individuals Date of registration: 07/08/2026 ^(mm/dd/yyyy)^ Last approval date : 07/08/2026 ^(mm/dd/yyy
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##### Public trial ## RBR-4cdm4k4 Study evaluating the effect of resveratrol on pain in women with lipedema Date of registration: 07/03/2026 ^(mm/dd/yyyy)^ Last approval date : 07/03/2026 ^(mm/dd/yyyy
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## RBR-2b7hw6b Impact of Resveratrol on the health of individuals with type 2 Diabetes Date of registration: 06/06/2026 ^(mm/dd/yyyy)^ Last approval date : 06/06/2026 ^(mm/dd/yyyy)^ ### Study type: In
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# Clinical Trials Using Quercetin Review the clinical trials studying quercetin on this list and use the filters to refine the results by age and location. Some clinical trials are held at NCI-Designa
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Pterostilbene is more bioavailable than resveratrol, but only a few clinical trials have tested it alone, so more evidence is needed. ... However, no clinical trials have confirmed these effects in h
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GeroScience. 2022 Dec 8;45(1):29–43. doi: 10.1007/s11357-022-00705-1 # The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multi
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# A Randomized Controlled Clinical Trial in Healthy Older Adults to Determine Efficacy of Glycine and N-Acetylcysteine Supplementation on Glutathione Redox Status and Oxidative Damage ... We investiga
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# Glycine supplementation extends lifespan of male and female mice ... Elevated glycine led to a small (4%–6%) but statistically significant lifespan increase, as well as an increase in maximum lifesp
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*Objectives*. The purpose of this trial was to evaluate the safety of long-term pterostilbene administration in humans. *Methodology*. The trial was a prospective, randomized, double-blind placebo-con
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We review completed and ongoing clinical trials of rapamycin and analogs for diseases of aging in humans, and discuss the challenges and side-effects of rapamycin that may limit its translation from t
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J Int Med Res. 2026 Feb 9;54(2):03000605251411151. doi: 10.1177/03000605251411151 # Effects of coenzyme Q10 analogs on oxidative stress, muscle, and metabolism after exercise: A meta-analysis and syst
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**Correspondence:** Shigeo Saito (saict1@maple.ocn.ne.jp), Kazunari K. Yokoyama (kazu@kmu.edu.tw) ... Revised 2025 Dec 30; Received 2025 Oct 25; Accepted 2026 Jan 14; Issue date 2026 Jan-Feb. ... Almo
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J Int Soc Sports Nutr. 2026 Jan 24;22(Suppl 1):2617283. doi: 10.1080/15502783.2026.2617283 # Short-term creatine supplementation enhances strength, reduces fatigue, and accelerates recovery in resista
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JAMA Netw Open. 2026 Jan 16;9(1):e2554152. doi: 10.1001/jamanetworkopen.2025.54152 # Berberine and Adiposity in Diabetes-Free Individuals With Obesity and MASLD A Randomized Clinical Trial Lubi Lei ..
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# Antihypertensive Effects of Curcumin/Turmeric Supplementation in Prediabetes and Diabetes: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials ... **Correspondence:** Hossein Bahar
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Trials. 2025 Oct 30;26:452. doi: 10.1186/s13063-025-09176-z # POLYamine treatment in elderly patients with Coronary Artery Disease (POLYCAD): study protocol for a Danish randomised, double-blind, plac
We conducted a placebo-controlled randomized pilot study with the primary objective of determining safety of NR in older adults with mild cognitive impairment (MCI). Twenty subjects with MCI were rand
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It is found to be beneficial against cardiovascular diseases, cancer, diabetes, neuro-degenerative diseases, allergy asthma, peptic ulcers, osteoporosis, arthritis, and eye disorders. ... A double-bli
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This trial examines how well the body absorbs three different versions of Coenzyme Q10, a supplement that may aid energy and cellular health. Participants will take these CoQ10 formulations over 71 da
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This trial tests berberine, a plant-based supplement, to determine its effectiveness in lowering cholesterol and blood sugar in people with metabolic syndrome. Metabolic syndrome consists of condition
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Age: 18+Sex: AnyTrial Phase: Phase 1Sponsor: Ohio State UniversityMust not be taking: Anti-arrhythmics, Antipsychotics, Anxiolytics, othersDisqualifiers: Coronary disease, Stroke, Liver disease, other
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## Palvella Therapeutics Announces First Patients Dosed in Phase 2 LOTU Trial of Fast Track-Designated QTORIN™ Rapamycin for Clinically Significant Angiokeratomas May 4, 2026 ... *Phase 2 single-arm,
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We report results from the largest randomized, double-blind, placebo-controlled trial of nicotinamide mononucleotide (NMN) supplementation to date. Over 12 months, participants receiving 500 mg/day NM
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## Assessment of the Effects and Safety of Spermidine Supplementation on Blood Lipids and Body Weight in Overweight or Obese Individuals With Hyperlipidemia ClinicalTrials.gov ID ** NCT07662330 Sponso
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## Phase II, Randomized, Double-blind, Placebo-controlled Clinical Trial to Evaluate the Efficacy and Safety of Omega-3 Fatty Acids as an Adjunct to Morphine in Acute Postoperative Pain (O3MORPH) Clin
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## Nicotinamide Riboside, Vit B3 Analogue, and Brain Energy Metabolism ClinicalTrials.gov ID ** NCT07649161 Sponsor ** Massachusetts General Hospital Information provided by ** MOHAMED, SOLIMAN, Massa
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## Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients (ALA-MYO-PCOS) ClinicalTrials.gov ID ** NCT07630779 Sponsor ** Beni-Suef University ... Last Update Posted **
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## Effects of Omega-3 Fatty Acids on Inflammation and Gut Microbiota in Celiac Disease (OMEGA-CD) ClinicalTrials.gov ID ** NCT07585669 Sponsor ** University of Chile Information provided by ** Univers
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## Alpha-Lipoic Acid in Mitigating Cisplatin-Induced Nephrotoxicity ClinicalTrials.gov ID ** NCT07564479 Sponsor ** Minia University Information provided by ** Asmaa Bassem Mohammed, Minia University
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Completed** ## Effects of 7-Day Creatine Supplementation on Cognitive Function After High-Intensity Interval Training in Active Young Men (HIITCRECOG) ClinicalTrials.gov ID ** NCT07534293 Sponsor ** U
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Completed** ## Effect of Curcumin Add-On Therapy on Quality of Life and IL-1β Levels in Patients With Schizophrenia (CUR-SCZ) ClinicalTrials.gov ID ** NCT07523256 Sponsor ** Rinvil Renaldi ... Last Up
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Not yet recruiting** ## Can People Achieve a Target Omega-3 Index by Following a Personalized Omega-3 Dosing Regimen? ClinicalTrials.gov ID ** NCT07480707 Sponsor ** Fatty Acid Research Institute ...
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## Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat ClinicalTrials.gov ID ** NCT07472426 Sponsor ** University of Northern Iowa I
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## Study on the Efficacy of Quercetin Intake in Patients With Fibrotic Interstitial Lung Diseases. ClinicalTrials.gov ID ** NCT07466420 Sponsor ** Katerina M. Antoniou Information provided by ** Kater
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Not yet recruiting** ## Berberine Phytosome for Signs and Symptoms of Polycystic Ovary Syndrome (PCOS) ClinicalTrials.gov ID ** NCT07465575 Sponsor ** Liaquat University of Medical & Health Sciences I
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Not yet recruiting** ## Study of the Safety and Usefulness of Liposomal Curcumin in Multiple Myeloma ClinicalTrials.gov ID ** NCT07456605 Sponsor ** University Health Network, Toronto Information prov
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Not yet recruiting** ## Effect of Low-Dose Versus High-Dose Alpha-Lipoic Acid on Oxidative Stress, Inflammation, and Clinical Outcomes in Acute Exacerbations of Chronic Obstructive Pulmonary Disease C
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## Evaluation of the Pharmacokinetics of Curcumin Capsules in Healthy HumanClinicalTrials.gov ID ## Study Overview Main objective: Through blood drug concentration testing, evaluate the post-meal phar
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## Influence of the Urolithin A on the Population With BMI Higher Than 30 During Restricted Eating. (Obesity UroA) ClinicalTrials.gov ID ** NCT07377136 Sponsor ** Charles University, Czech Republic In
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## Clinical Effects of Two Oral Bioactive Collagen Peptides On Skin Properties and Aging Hallmarks ClinicalTrials.gov ID ** NCT07302789 Sponsor ** Bionos Biotech S.L. ... (Responsible Party) Last Upda
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## A Clinical Trial to Assess the Pharmacokinetic Profile of Three Coenzyme Q10 Formulations in Healthy AdultsClinicalTrials.gov ID ## Study Overview The goal of this clinical trial is to assess the p
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## The Effect of Urolithin A (Mitopure®) Supplementation on Muscle Strength in Healthy Middle-Aged Adults (ATLAS 2)ClinicalTrials.gov ID ## Study Overview Dietary Supplement: Placebo Dietary Supplemen
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## Nicotinamide Mononucleotide Supplementation for Exercise Tolerance Improvement in Healthy Older Adults ClinicalTrials.gov ID ** NCT07144527 Sponsor ** Scott Silveira ... Last Update Posted ** 2026-
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Recruiting soon # Omega-3 Fatty Acid Supplementation for Adult and Juvenile Dermatomyositis What is being tested ## FISH OIL 500MG OMEGA-3 SOFT GEL MINIS + Placebo Dietary Supplement Who is being recr
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## Creatine and Resistance Training in Older Adults With Mild Cognitive Impairment ClinicalTrials.gov ID ** NCT06948149 Sponsor ** Western University, Canada ... Last Update Posted ** 2026-05-19 ... T
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## Intervention of Nicotinamide Mononucleotide in Middle-aged and Elderly People (NMNAGING) ClinicalTrials.gov ID ** NCT06592859 Sponsor ** People's Hospital of Quzhou Information provided by ** Feng
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## Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With MultimorbidityClinicalTrials.gov ID ... We will conduct a clinical trial in healthy volunteers and older patients with multiple
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# FIRST Fisetin to Reduce Senescence and Mobility Impairment in Peripheral Artery Disease: the FIRST Pilot Randomized Trial Qué se está evaluando ... ## Estudio de Tratamiento Controlado con PlaceboFa
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Recruiting Phase 1 Phase 2 ## Fisetin Fisetin to Improve Vascular Function in Older Adults Sponsor: University of Colorado, Boulder Code: NCT06133634 Conditions Aging Endothelial Dysfunction Arterial
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## Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt (MIRACLE-ALA)ClinicalTrials.gov ID ## Study Overview This is a multicenter, interve
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ClinicalTrials.gov record Not yet recruiting Phase 2 Interventional Accepts healthy volunteers # Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity ClinicalT
## An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood CancerClinicalTrials.gov ID ## Study Overview This is a first-in survivor pilot study with
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Active Not Recruiting NA INTERVENTIONAL 2-arm NCT04562831 # The NO-ALS Study: A Trial of Nicotinamide/Pterostilbene Supplement in ALS. A Randomized Placebo-controlled Trial of Nicotinamide/Pterostilbe
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Suspended # The Study of Berberine Affecting Metabolism, Inflammation Status, Endothelial Function and Thrombotic Events in Patients With Coronary Artery Disease by Remodeling Gut Microbiota What is b
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## Resveratrol for Improved Performance in the Elderly (RIPE)ClinicalTrials.gov ID ## Study Overview Dietary Supplement: Placebo Drug: Low dose Resveratrol Drug: High dose Resveratrol - 238-2009 ## Co
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# Metformin Shows Promise for Slowing Cellular Aging in Prediabetic Adults Six-month trial examines whether metformin treatment can improve telomere length and longevity gene expression in prediabetic
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Updated June 21, 2026: metformin for longevity, TAME status, no validated anti-aging dosage, B12, muscle risks and medical supervision. ... **Should healthy adults take metformin for longevity?** For
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The most-prescribed oral diabetes drug in history has one of the strongest observational longevity signals in medicine — diabetics on metformin outliving non-diabetic controls in some analyses. The TA
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# Metformin Shows Anti-Aging Benefits: TAME Trial Reports 18% Reduction in Age-Related Disease ... The long-awaited results from the Targeting Aging with Metformin (TAME) trial — the first clinical tr
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By 2026, that mouse result has spawned a field, a community of biohackers self-experimenting with off-label prescriptions, a longevity telehealth industry, and — crucially — the first completed random
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- - - A new study by Christopher Martens (left), associate professor of kinesiology and applied physiology and Kevin Decker (right), a KAAP postdoctoral researcher, found nicotinamide riboside (NR), w
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|最近我々は、マウスを用いた動物試験により、レスベラトロール類の一つであるプテロスチルベンが、高齢卵子で減少している抗老化遺伝子SIRTの発現を増加させ、エイジングにより低下したミトコンドリア機能を向上させ、その結果妊娠率が改善することを見出した（特願：2016-187572, PCT/JP2017/34361）。そこで本研究では、動物試験においてエイジング卵子の質の改善に対する有用性を確認したサ
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**Methods:**In this double-blind, prospective, placebo-controlled trial (NCT05735886) we sought to characterize for the first time the effects of UA on the human immune system. Fifty healthy participa
A cluster of fisetin clinical trials registered between 2020 and 2024 are reaching their expected data windows in 2025 and 2026. ... The registered fisetin Phase 1-2 human trial landscape has expanded
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# — March 13, 2026 · Creatine: 685 Clinical Trials ... In 2025, **Dr. Richard B. Kreider** and colleagues at Texas A&M University published a comprehensive analysis of **685 clinical trials** involvin
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Health Sci Rep. 2026 Feb 28;9(3):e71920. doi: 10.1002/hsr2.71920 ... Registered clinical trials (in the completed or terminated status) regarding the effects of quercetin on various cancers/malignanci
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Homa Shalchi 713-798-4710 Houston, TX ... A randomized, double blind human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC – a combinatio
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Emerging Subjective sleep quality in adults with self-reported poor sleep EmergingClinical Metabolic markers (glucose, insulin sensitivity, HbA1c) in diabetic populations EmergingClinical Ageing hallm
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GlyNAC — the combination of glycine and N-acetylcysteine — addresses glutathione deficiency, which increases with age and correlates with multiple aging hallmarks. The human RCT evidence is small but
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### Nicotinamide Riboside for Veterans (NR-VETS) This trial examines nicotinamide riboside (NR), a form of vitamin B3, for its potential to improve physical and cognitive performance and sleep quality
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- https://doi.org/10.1016/j.nfs.2025.100258 # Safety evaluation of a soluble granular food containing quercetin glycosides for healthy adults: A randomized controlled trial - Mar 1, 2026 - NFS Journal
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The first real human randomized controlled trial of rapamycin just published, and the results are not what the longevity world expected. The study (RAPA-EX-01, published April 2026, Journal of Cachexi
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Received 14th April 2026 , Accepted 6th June 2026 First published on 15th June 2026 ## Abstract ... Taurine supplementation has shown promising outcomes in human studies, with emerging relevance in pr
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This edition features four recent studies examining the role of collagen in supporting skin health and joint function. ### ### The sustained effects of bioactive collagen peptides on skin health: a ra
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# NCT07657390 Nicotinamide riboside/Pterostilbene Cancer Pain Clinical Landscape Report 2026: Design, Endpoints, Sponsor and Readout Outlook 4 August 2026 ... *MCP evidence snapshot: 4 August 2026. Tr
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# ChiCTR2600123561 Nicotinamide riboside/Pterostilbene Adult Acute Myeloblastic Leukemia Clinical Landscape Report 2026: Design, Endpoints, Sponsor and Readout Outlook 24 July 2026 ... *MCP evidence s
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# Comparing the Effects of Commercially Available Dietary Supplements on CoQ10 Concentrations O ... Status and phase Completed Phase 3 Phase 2 Conditions Health Wellness Treatments Dietary Supplement:
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Still, NMN human trials have consistently shown positive results for safety and efficacy, significant increases in NAD+ levels, and crucially, that NMN can benefit humans in ways similar to the famous
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Project Details # TauAge randomised, controlled pilot trial: Does taurine supplementation with 4 g/day for 6 months slow human ageing? Subject Area Biogerontology and Geriatric Medicine Term since 202
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# Efficacy and Safety of Berberine in Treating Type 2 Diabetes Mellitus: a Bayesian Network Meta-Analysis of Randomized Controlled Trials ## General information ... Posted Content DOI 10.2139/ssrn.638
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Call us at 1-855-329-5969.
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# Combined Aerobic-Resistance Training and Taurine Supplementation Reduce Asprosin and Elevate Spexin in Men with Obesity: A 12-Week Supplement-Blinded, Randomized Controlled Trial Nutrients. 2026 Jul
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# Effect of curcumin compared to chlorhexidine on clinical variables of periodontal health: A systematic review and meta-analysis of randomized controlled trials Medicine (Baltimore). 2026 Jul 24;105(
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# A phase-II randomized controlled pilot study of nicotinamide riboside supplementation in older adults with amnestic mild cognitive impairment Alzheimers Dement. 2026 Jul;22(7):e71605. doi: 10.1002/a
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# Assessment of the Efficacy of Quercetin in Adult Patients With Autism Spectrum Disorder: A Randomized, Triple-Blind, Placebo-Controlled Trial Hum Psychopharmacol. 2026 Jul;41(4):e70057. doi: 10.1002
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# Does creatine supplementation improve strength and power in physically active individuals on a vegan diet? a randomized, triple-blind, placebo-controlled trial Eur J Appl Physiol. 2026 Jul 2. doi: 1
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# Evaluating a Coenzyme Q10-Based Food for Special Medical Purpose, for Mitochondrial Diseases Management: An Open-Label, Pilot Trial Int J Mol Sci. 2026 Jun 5;27(11):5127. doi: 10.3390/ijms27115127.
# Curcumin-piperine supplementation modulates inflammation, oxidative stress, and cardiometabolic risk: a systematic review of randomized controlled trials Front Nutr. 2026 May 18:13:1814168. doi: 10.
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# 12‑weeks fisetin supplementation and interval resistance with aerobic training: changes in Maresin‑1 and inflammatory markers in men with obesity: a randomized controlled trial J Int Soc Sports Nutr
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# Effects of taurine supplementation on metabolic health and biological aging in healthcare workers: A protocol for a triple-blinded, Bayesian-optimized phase II randomized controlled trial PLoS One.
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# Spermidine Mitigates Immune Cell Senescence and Boosts Vaccine Responses in Healthy Older Adults-A Pilot Study Aging Cell. 2026 Jun;25(6):e70545. doi: 10.1111/acel.70545. ... Older adults are highly
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# Krill oil increase plasma omega-3 fatty acids more than fish oil in healthy adults: a double blind randomized controlled trial Am J Clin Nutr. 2026 May 16:101346. doi: 10.1016/j.ajcnut.2026.101346.
Mol Biol Rep. 2026 May 12;53(1):746. doi: 10.1007/s11033-026-11950-4. ... ** A preclinical study indicates that UA alters cancer cell metabolism, fortifies the intestinal barrier, safeguards the brain
# A randomized controlled trial of L-taurine for fatigue in decompensated cirrhosis Hepatol Commun. 2026 Apr 24;10(5):e0938. doi: 10.1097/HC9.0000000000000938. eCollection 2026 May 1. ... We hypothesi
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# The Additive Effects of Curcumin Supplementation in Addition to an Anti-Inflammatory Diet on Inflammatory Indices in Patients With Hashimoto's Thyroiditis (HT): A Double Blind Randomized Controlled
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# Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials Nutr J. 2026 Apr 15. doi: 10.1186/s1293
# Creatine supplementation on fatigue related to post-COVID-19 condition-fatigue study: a randomized controlled trial Front Nutr. 2026 Mar 25:13:1731306. doi: 10.3389/fnut.2026.1731306. eCollection 20
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# Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials Front Med (Lausanne). 2026 Mar 17:13:1618306. doi: 10.3389/fmed.2026.1618306. eCollectio
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. 2026 Mar 11:13:1711478. doi: 10.3389/fnut.2026.1711478. eCollection 2026. # A nutritional blend of taurine, vitamins B6, B9, and B12 improves motivated behaviors in healthy adults-a double-blinded r
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# Resveratrol and Renal Biomarkers in Type 2 Diabetes: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials Diabetes Metab Syndr Obes. 2026 Jan 28:19:402309. doi: 10.2147/DMS
# A phase II randomized placebo-controlled study of fisetin to improve physical function in breast cancer survivors: the TROFFi study rationale and trial design Ther Adv Med Oncol. 2026 Mar 11:18:1758
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Dose Response. 2026 Mar 6;24(1):15593258261419728. doi: 10.1177/15593258261419728. eCollection 2026 Jan-Mar. ... ** This study aimed to evaluate the concentration, stability, and cost-concentration of
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# Immune Preconditioning with Oral Quercetin Supplement and COVID-19 mRNA Vaccine Responses: A Randomized, Double-Blind, Placebo-Controlled Trial J Nutr. 2026 Apr;156(4):101431. doi: 10.1016/j.tjnut.2
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# Could taurine supplementation improve graft functions after liver transplantation? A randomized clinical trial among liver transplant recipients Clin Nutr ESPEN. 2026 Jan 26:72:102920. doi: 10.1016/
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# Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial Front Aging. 2025 Dec 19:6:1727244. doi: 10.3389/fragi.2025.172
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# Impact of Alpha Lipoic Acid as an Adjuvant Therapy on Inflammation and Fibrosis in Type 2 Diabetic Patients with Ischemic Cardiomyopathy: A Randomized Controlled Trial J Diet Suppl. 2026;23(1):1-22.
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# Effects of Coenzyme Q10 Supplementation on Depressive Symptoms and Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Trials J Clin Psychopharmacol. 2026 Jan-Feb;46(1):93-100. d
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# The Effects of 8-Week Creatine Hydrochloride and Creatine Ethyl Ester Supplementation on Cognition, Clinical Outcomes, and Brain Creatine Levels in Perimenopausal and Menopausal Women (CONCRET-MENOP
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# Effect of Coenzyme Q10 Supplementation on Cardiac Function and Quality of Life in Patients with Heart Failure: A Randomized Controlled Trial J Clin Med. 2025 May 23;14(11):3675. doi: 10.3390/jcm1411
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Objective To evaluate the efficacy of fisetin, a senolytic flavonoid, compared with placebo in adults with CVID-associated GLILD. Methods We conducted a randomized, double-blind, placebo-controlled pi
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Schwarz C, Benson GS, Horn N, et al. Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial. JAMA Netw Open. 2
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**Everolimus Aging Study (NCT05835999)** - **What’s being done:** low-dose everolimus to test whether mTORC1 inhibition can improve physiological and molecular hallmarks of aging. ... - **Phase / stat
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Importance: Preclinical and human observational studies suggest that metformin may decrease age-related pathology, including frailty. Objective: Determine whether metformin reduces frailty progression
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Clinical Research and Public HealthClinical trialsNephrology Open Access | 10.1172/jci.insight.167274 # Randomized crossover clinical trial of coenzyme Q10 and nicotinamide riboside in chronic kidney
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A new meta-analysis led by researchers from the Fatty Acid Research Institute (FARI) provides the clearest picture to date of the relationship between omega-3 fatty acid supplementation and atrial fib
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## Our mission is to end the threat of age-related disease for this and future generations We believe it is possible for people to enjoy their lives at 95 as much as they do at 25, and to achieve that
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### Epigenetic clocks can accurately predict a person’s biological age. The processes behind this have now been specifically examined. 07/20/2026 · News · Leibniz-Institut für Alternsforschung - Fritz
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February 26, 2026 . News # THRIVE: Transforming Health: Reclaiming Intrinsic Vitality for Everyone ##### Stanford-led Coalition Secures up to $34.5M Award to Develop the First FDA-Grade "Intrinsic Cap
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The Paul F. Glenn Center for Biology of Aging Research at Stanford University is focused on the fundamental biological processes that drive cellular, tissue, and organismal aging, with a particular em
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# San Antonio's Barshop Institute to test three approved drugs for slowing aging ... At UT Health San Antonio’s Sam and Ann Barshop Institute, researchers are preparing a major new test of an old scie
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Wed, Jan 7, 2026 4pm to 5pm Sam and Ann Barshop Institute for Longevity and Aging Studies, 2.2005 Stream Available Wed, Jan 14, 2026 4pm to 5pm Sam and Ann Barshop Institute for Longevity and Aging St
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Publicerad: 2026-04-23 11:12 | Uppdaterad: 2026-04-23 15:12 ... Verksamhetsrapporten 2023–2025 ger en översikt av Aging Research Center (ARC):s tvärvetenskapliga forskning om hjärnans åldrande, demens
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NIA Intervention Testing Program (ITP) Announces Annual Call for Compounds to Test for Lifespan Extension in Mice Notice Number: NOT-AG-25-014 ## Key Dates Release Date: February 18, 2026 ## Related
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05/21/2026 13:01 * ... As we age, our cells lose energy and adaptability—a process closely linked to the function of mitochondria, the cell’s “powerhouses”. Researchers at the Leibniz Institute on Agi
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## March 16th, 2026: Geneticist Anne Brunet explores the science of aging The professor of genetics breaks down what aging really is, how lifestyle choices influence longevity, and the promising front
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# New Buck Initiative: The Next Frontier in Healthy Aging 04/23 April 23, 2026 . EVENTS ### When April 23, 2026 4:00 pm - 5:00 pm ### Bookings Bookings closed ### Where Buck Institute for Research on
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Congratulations to Professor Miles Witham, co-lead of the AGE Research Group, who has been appointed as a Senior Investigator by the National Institute for Health and Care Research (NIHR).
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Valter Longo, PhD, is the Edna Jones Professor in Gerontology and Professor in Biological Science. He is also the Director of the USC Longevity Institute. He is interested in understanding the fundame
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### The killifish reveals in fast-forward what takes decades in humans: chronic inflammation, DNA damage in precursor cells and remodelling processes in the blood-forming organ characterise the ageing
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The ITP has tested dozens of interventions for lifespan extension in mice at three independent sites simultaneously. ... The NIA Interventions Testing Program is the most methodologically rigorous lon
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The research, by a team at Newcastle University’s Institute for Ageing and Health, used a systems biology approach to unravel the molecular pathway that occurs when DNA damage triggers cells to shut d
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The Interventions Testing Program (ITP) is a peer-reviewed program designed to identify agents that extend lifespan and healthspan in mice. Investigators at any university, institute, company, or othe
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The IHA is a centre of excellence for research on the biology of ageing and ageing related diseases. ... Upcoming Events 06 Nov in person Understanding evolution through game theory: Insights from stu
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### 15th AHA Conference ### 1st EFAR Conference ... For Masterprogramme at the Cologne Graduate School of Ageing Research! ... Researchers from the CECAD Cluster of Excellence for Aging Research found
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# Highlights from the 2026 Paul F. Glenn/AFAR Conference on the Biology of Aging and the 39th Annual AFAR Grantee Conference From May 27 - 29, 2026, AFAR hosted the joint annual** Paul F. Glenn/AFAR C
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**Healthy Ageing Symposium: living better for longer** Bringing together academics, industry leaders and charity representatives, the event aimed to address the challenges of ageing healthily. In part
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11/06/2026 BGU-led MRI study links lasting visceral fat loss to lower long-term type 2 diabetes risk despite weight regain. ... BGU study finds sustained visceral fat reduction preserves brain structu
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# Half-time seminars Half-time Seminar: Franziska Steffens 27-08-2026 9:30 am - 12:00 pm Add to iCal Campus Solna Karolina lecture hall, Widerströmska huset, Tomtebodavägen 18a, Solna "Old-age depress
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**The Paul F. Glenn Center for Biology of Aging Research at Stanford University** is focused on the fundamental biological processes that drive cellular, tissue, and organismal aging, with an emphasis
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At the IHA, we study how gene expression impacts ageing, using organisms ranging from a single-cell eukaryote, the fission yeast, to animal models, such as worm and flies. We use a plethora of methods
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Home Events Public Events Scientific Events All Events Upcoming Lectures and Events Cologne Seminars on Ageing "Uncovering Hidden Diseases: Genotype-First Insights into How Ubiquitylation Controls Neu
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Het **ERIBA** (afkorting van *European Research Institute of the Biology of Ageing*) is een onderzoeksinstituut van het Universitair Medisch Centrum Groningen en de Rijksuniversiteit Groningen waar we
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## Media contact ## Mark Greaves m.greaves [at] ucl.ac.uk +44 (0)20 3108 9485
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Leyden Academy visits the Aging Research Center (ARC) and TraCeDem at Karolinska Institutet on 21 May 2026. ... On 21 May 2026, a delegation from Leyden Academy on Vitality and Ageing visited the Agin
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Wir erforschen die molekularen, physiologischen und evolutionären Mechanismen des Alterns. ... ## Veranstaltungen ### #### MPI AGE seminar: "Mitochondrial homeostasis and turnover" 13.04.2026 13:00 -
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Marcia Haigis David Sinclair Amy Wagers Bruce Yankner Register Now for the 2026 Symposium Download the 2026 Brochure Paul F. Glenn Center for Biology of Aging Research Harvard Medical School New Resea
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The European Research Institute for the Biology of Ageing (ERIBA), part of the UMCG and the University of Groningen, has partnered with leading centres across Europe to launch the European Federation
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The federation's inaugural congress will take place from 14 to 16 October 2026, hosted by the CECAD Cluster of Excellence in Aging Research at the University of Cologne. ## Overview - **Edition** Inau
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NOVATO, Calif., March 05, 2026 (GLOBE NEWSWIRE) -- The Buck Institute for Research on Aging today announced the launch of **Healthspan Horizons**, a new initiative designed to transform how healthspan
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# Buck Institute Launches AI-Powered Healthspan Initiative and Secures $34.5M ARPA-H Grant Buck Institute unveils Healthspan Horizons AI platform and joins Stanford coalition to develop FDA-grade agin
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Scientists at the Max Planck Institute for the Biology of Ageing study how cells age during their lifetime and examine which genes and environmental factors are involved in the process. ... ### Contac
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*Contact: Steven Lee, (210) 450-3823, lees22@uthscsa.edu* SAN ANTONIO (February 24, 2026) Positioning The University of Texas at San Antonio as a national anchor for aging and longevity science, its S
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# Stress and Aging: Implications for Alzheimer’s and Parkinson’s # Stress and Aging: Implications for Alzheimer’s and Parkinson’s April 28, 2026 Medical Research ... **Ynet News—** Prof. Debbie Toiber
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Published: 26-02-2026 10:25 | Updated: 26-02-2026 10:25 # Aging Research Center (ARC) offered an educational day focused on aging research ... When ARC turned 25 last year, they received a grant from
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## We improve health across the life course and help people age well Our work brings together discovery science, clinical care, public health knowledge, and community insight. We turn research into ac
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The mission of the European Institute for the Biology of Ageing (ERIBA) is to better understand what causes ageing. Our studies are focused on the mechanisms that result in loss of cells with age and
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# Public health in the age of longevity interventions: from prevention to system-wide resilience Aging (Albany NY). 2026 May 18;18(1):572-574. doi: 10.18632/aging.206381. Epub 2026 May 18. ... Jochen
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Cytokine Growth Factor Rev. 2026 Apr 1:89:5-14. doi: 10.1016/j.cytogfr.2026.03.001. Online ahead of print. ... - ^1^ European Research Institute for the Biology of Ageing (ERIBA), University Medical C
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Symposium on Aging The 2026 Paul F. Glenn Center for the Biology of Aging Research BLAVATNIK INSTITUTE HARVARD MEDICAL SCHOOL The Paul F. Glenn Center for the Biology of Aging Research Each year the C
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CONFERENCE ON THE BIOLOGY OF AGING 39th Annual Glenn AFAR Grantee Conference Ritz-Carlton Bacara, Santa Barbara, California May 27 - 29, 2026 Table of Contents ... The Paul F. Glenn/AFAR Conferenc
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**When & Where: ** **Date: 14th - 16th October 2026** **Venue: MPI for Biology of Ageing & CECAD Research Center, Cologne, Germany** **You can now register for the event in our Registration Tool:** **
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NIH's National Institute on Aging is seeking proposals for compounds to be tested through the Interventions Testing Program (ITP), which measures the ability to extend lifespan and/or delay the onset
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- ^1^ Institute for Ageing and Health, University of Newcastle, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, UK. j.a.edwardson@ncl.ac.uk - PMID: 12175475 ... The Institute F
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BEER-SHEVA, Israel, October 29, 2025 – Ben-Gurion University of the Negev's Prof. Alon Monsonego had discovered that T helper lymphocytes, a subset of immune cells which regulate immunity, undergo fun
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Verified adverse-event reports for 10 key ingredients against an official government adverse-event database. Created a safety signal layer with report counts, top reactions, and priority ratings for e
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Multi-platform review compilation covering Trustpilot ratings across 5 markets, independent lab tests, clinical evidence on the sachet product, competitor comparisons, and critical voices.
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A review of claim conflicts, adverse-event signals, commercial context, and methodology limits around the Blueprint protocol.
Added 6 protocol_audit_events to blueprint-experiments.json; Updated 5 existing experiment_entries with new verified data
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Chen, Wang, Romandini and Michaud analysed 1,926 adults aged 50 years and older from the 1999–2002 National Health and Nutrition Examination Survey. They compared periodontal status and edentulism wit
Baldassarre and colleagues assessed oral semaglutide in routine care over 24 months in 232 adults with type 2 diabetes. Mean HbA1c fell by 0.8 percentage points and weight by 5.7 kg. Forty-four percen
Evidence-based Dentistry published a commentary on a double-blind, placebo-controlled trial by Lucchesi et al. (Clin Oral Invest 2025). Thirty-eight adult smokers with Stage III or IV, Grade C periodo
Every time a product's score, rank, or verdict changes, the before and after values, our reasoning, and the sources that triggered it are recorded here. Nothing is edited silently.
A new human NMN trial adjusted the evidence weighting for NAD+ boosters, raising this product's overall score and category rank.
The new trial (n=120, 12-week double-blind) showed a statistically significant increase in whole-blood NAD+ levels at 500 mg/day NMN, with no reported adverse events. This moved the evidence grade for NMN from B to B+, which raised the dose-evidence ceiling for all NMN products. DoNotAge Pure NMN already met the research dose at 500 mg per serving, so its overall score climbed from 7.3 to 10.5. We now list it as Recommended in the NAD+ booster category. Buyers looking for a single-ingredient NMN at the research dose should consider this product; those wanting a multi-ingredient stack should compare with Elysium Basis or Wonderfeel Youngr.
Our scores are editorial judgments, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. Read how we score →