Strain-specific benefits; forget 'total CFU' marketing.
Only take probiotics tied to specific strain-RCT evidence. Ignore CFU count marketing.
Probiotics (Probiotic strains) is a microbiome with evidence grade B, meaning it is supported by human RCTs. We track 4 products containing Probiotics. Typical doses range from 100 to 900 mg per serving. The top-ranked product scores 6.1 out of 10 on our composite scale (dose, evidence, price, testing, transparency). Prices range up to $99.00 per month.
| Product | Brand | Dose | Price/mo | 3rd-party tested | Score |
|---|---|---|---|---|---|
| DS-01® Daily Synbiotic | Seed Health | 900 mg | $60.00 | Yes | 6.1 |
| AG1 Foundational Nutrition | AG1 (Athletic Greens) | 500 mg | $99.00 | Yes | 6.0 |
| Seed AM-02 Energy + Focus | Seed Health | 100 mg | $34.99 | Yes | 5.5 |
| Seed PM-02 Sleep + Restore | Seed Health | 200 mg | $34.99 | Yes | 5.3 |
Scores are editorial judgments, not a scientific standard. See how we score.
Live bacteria that transit or colonize your gut. Effects are strain-specific, not species-specific, L. rhamnosus GG and L. plantarum 299v do very different things.
Specific strains have RCTs for diarrhea, IBS, atopic disease. Generic 'probiotic' products lack specific-strain evidence.
Only take probiotics tied to specific strain-RCT evidence. Ignore CFU count marketing.
Live microbes at labelled CFU count at expiry.
Strain-specific evidence documented in AGA and BSG guidelines.
Transit-dependent.
Refrigerated ≠ better if the strain is shelf-stable. Look for CFU at expiry, not at manufacture.
The trial dose above is our editorial pick from the published human trials for this ingredient. We choose the dose that the best-available studies used on the endpoint most relevant to longevity. The range shows the lowest and highest doses tested in published trials. The landmark studies below are the papers we read to set it. You can click through and check our work.
When new trials publish, our automated sweeps flag them. If a new study materially changes the dose, we update it through editorial review and record the old dose, new dose, and the triggering study in every affected product's recommendation history. The dose is never changed automatically.
Regulatory events, evidence grade changes, and key research milestones for Probiotics, most recent first. Studies link to the paper; regulatory entries name and link the responsible authority.
All products in our catalog that contain Probiotics, ranked by our overall score. Ranking is editorial, never paid.
Seed HealthCFU not stored
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
AG1 (Athletic Greens)CFU not stored
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Seed HealthCFU not stored
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Seed HealthCFU not stored
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Molecules in the same class, plus the actives most often formulated alongside Probiotics in our catalogue.
See Probiotics in context: the mechanism it acts through, the biomarker it moves, the products that dose it, and the trials that tested it.
View Probiotics on the Longevity Map →Live bacteria that transit or colonize your gut. Effects are strain-specific, not species-specific, L. rhamnosus GG and L. plantarum 299v do very different things.
The trial dose in published human studies is 0 mg per day, with a range of 0 to 0 mg per day. Always consult a qualified clinician before starting any supplement.
Refrigerated ≠ better if the strain is shelf-stable. Look for CFU at expiry, not at manufacture.
We track 4 products containing Probiotics. The top-ranked product scores 6.1 out of 10 on our composite scale, which evaluates dose, evidence, price, third-party testing, and transparency. See the comparison table above. Scores are editorial judgments, not a scientific standard.
Probiotics has evidence grade B, meaning it is supported by human RCTs. Grade A means replicated human RCTs with hard endpoints. Grade B means human RCTs with biomarker outcomes. Grade C means mixed or small human trials. See our evidence grading methodology.
Evidence grades are reviewed when new human RCTs are published. Product counts update automatically as new products are added. Dose ranges reflect published trial data, not brand recommendations. Read how we verify.