Basics: short version, verdict first People Molecules Peptides Biomarkers Studies Stem Cells Editorial Methodology
Layer 1 · Decision
← All products
Jarrow Formulas

Jarrow Formulas Alpha Lipoic Sustain with Biotin, 300 mg

Mitochondrial · Tablet · 60 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Active per serving
Alpha-Lipoic Acid 300 mg
Form
Tablet
List price (catalog, USD)
$24.64
Price per serving
$0.41List price divided by servings per container. A per-day cost only if the label serving is once daily.
Full label record: servings, testing, ingredients
Servings per container
60
Catalog monthly estimate
$12.32
Testing disclosure
No third-party testing listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

IngredientAmount per serving
Alpha-Lipoic Acid300 mg

What to check on the label

  • Which form of the compound the label names (for CoQ10: ubiquinol or ubiquinone) and whether the milligrams refer to that form.
  • Softgel oil carriers are listed under 'other ingredients'. They are not part of the active amount.
  • Branded ingredients (Mitopure, BioPQQ and similar) should be named on the label if the brand claims them.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

7.7/10
Overall score
#9 / 30 in Mitochondrial

Full trial dose, top 29% value.

Read the evidence (3 studies)
Add to compareVisit brand site →
Watch out
Tier 3
Ingredient RCT (matching dose)
The ingredient was tested in an RCT at the same dose this product sells.
See the 3 supporting studies
How we scored this product Show the full breakdown
Dose vs. studies (50%) Why 9.0 of 10. Primary ingredient is Alpha-Lipoic Acid (evidence grade A). It delivers 300 mg, inside the studied range of 300–1200 mg. Read the rule → 9.0
Transparency (20%) Why 6.0 of 10. Earned points for all doses disclosed. Lost points for no public certificate of analysis and no independent third-party testing. Read the rule → 6.0
Value (10%) Why 9.0 of 10. One day at the trial dose costs about $0.82. That is cheaper than average (98 of 313 by cost per effective day). Read the rule → 9.0
Formulation (10%) Why 5.0 of 10. No published absorption advantage or disadvantage on file. The default of 5 is not a criticism. Read the rule → 5.0 Default. No absorption data on file.
Safety (5%) Why 5.0 of 10. Baseline 5.0. Third-party testing adds 2.0. Public lab certificate adds 1.5. NSF, USP or Informed Choice certification adds 1.5. Active safety signal subtracts 3.0. Read the rule → 5.0
Community sentiment (5%) Why 6.3 of 10. No external reviews found, so community sentiment defaults to neutral. Community never counts as clinical evidence. Read the rule → 6.3
Composite How this 7.7 is built. 0.50 × 9.0 + 0.20 × 6.0 + 0.10 × 9.0 + 0.10 × 5.0 + 0.05 × 5.0 + 0.05 × 6.3 = 7.7 out of 10. Safety caps applied after. 7.7
7.7 composite
Dose vs. studies50%9.0
Transparency20%6.0
Value10%9.0
Formulation10%5.0
Safety5%5.0
Community5%6.3

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Editorial verdict

Quick verdict

7.7 / 10
Best for
Full trial dose, Budget-friendly
Avoid if
No public lab certificate
Full-dose status
Meets trial dose
Price/month
$12
COA status
Not public
Biggest caveat
No third-party testing, which caps the quality transparency.
Nearest alternatives
Catalog snapshot. Check linked sources for current price, label and batch-specific testing.
Price verification
Current price: $24.64
Last price check: Sep 01, 2026
Add to compareVisit brand site →
Layer 2 · Context
In plain language

Why this scored this way

This Jarrow Formulas Jarrow Formulas Alpha Lipoic Sustain with Biotin, 300 mg scores 7.7, making it a strong scorer. It delivers 300mg of Alpha-Lipoic Acid, inside the studied range of 300–1200mg with grade A evidence (strong human trial data). The quality transparency (6.0) is limited by the lack of third-party testing.

What drives the score up

  • Dose-evidence score of 9.0 reflects good alignment with trial doses.
  • Alpha-Lipoic Acid is dosed at the full research level with grade A evidence (strong human trial data).

What drags it down

  • No third-party testing, which caps the quality transparency.
  • Quality transparency of 6.0 is below the site average.
  • Limited consumer feedback (community score: 6.3).

Why you'd choose it

  • You want a reasonably priced mitochondrial product.
  • You want Alpha-Lipoic Acid from a Jarrow Formulas product.
  • You want doses that align with published research.

Why you might skip it

  • You want third-party verified purity.
  • You want a product with a publicly available CoA.
  • You want stronger transparency (this scores 6.0).
Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Alpha-Lipoic Acid

Mitochondrial cofactor with genuine efficacy in diabetic neuropathy.

4 landmark RCTs · US: Dietary supplement · EU: Restricted in Italy/EU (safety review); food supplement elsewhere
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
100% of trial dose
Meets or exceeds the published effective dose
Cost at trial dose
$0.82/day at trial dose
What one effective daily dose actually costs
Transparency
6.0/10 · No public lab certificate
No third-party testing disclosed
Consumer signals
16,788 reviews across platforms · 4.6/5 · medium confidence
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

No public lab certificate
Certificate of Analysis not published
Without a public lab certificate, batch purity and potency cannot be independently verified.
No third-party testing
Independent lab verification not disclosed
The brand does not publish evidence of independent batch testing.
Buyer complaints
Trustpilot: limited review volume on Trustpilot directly; Amazon: biotin inclusion not wanted by all users
Recurring themes from consumer review platforms.
Plain English

What’s inside

The main ingredients of this product, in plain language.

Alpha-Lipoic Acid300 mgEvidence A

Mitochondrial cofactor with genuine efficacy in diabetic neuropathy.

Read about Alpha-Lipoic Acid →
Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price
$25
per bottle · 60 servings
Dose vs. research
of trial dose 100%
of published effective dose
$ / day at studied dose
$0.82
what one effective daily dose costs
$ / g active
$1.37
per gram of active substance
Independently checked

Data verification

COA status
Not public
Evidence grade
A
Per-ingredient breakdown
AAlpha-Lipoic Acid

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Evidence
300 mg 50% of trial dose
600 mg
3.2 /5
High confidence
16,794 reviews across 4 platforms (4 sources)
Source diversity: 92%
AmazonRedditTrustpilotiHerb
Praisetrusted supplement manufacturersupports blood sugar management
Complaintslimited review volume on Trustpilot directlybiotin inclusion not wanted by all users
Last checked: 2026-08-20

Consumer signals

4.6 out of 5 across 16,788 verified reviews on 4 platforms.

Medium confidence

Consumer sentiment compiled from 4 public sources.

Trustpilot

6 reviews · 3.0/5 · positive sentiment

Praisetrusted supplement manufacturer
Complaintslimited review volume on Trustpilot directly
Themes

Jarrow Formulas brand reviews trend positive across its product range.

Compiled from Trustpilot listing located during research; verified at build time.

Amazon

16,788 reviews · positive sentiment

Praisesupports blood sugar managementsustained release valued
Complaintsbiotin inclusion not wanted by all users
Themes

Amazon reviewers appreciate the extended-release ALA format for glucose support.

Compiled from Amazon listing located during research; verified at build time.

iHerb

positive sentiment

Praisehigh quality with no side effects reported
Complaintssome prefer R-ALA over standard ALA
Themes

iHerb reviewers report good tolerability and consistent quality.

Compiled from iHerb listing located during research; verified at build time.

Reddit

1 thread discussed · mixed sentiment

Praiseconsidered superior due to extended-release formula
Complaintsdebate over ALA vs R-ALA efficacy
Themes

Reddit discussions debate whether the sustained-release format offers real advantages over R-ALA.

Compiled from Reddit listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Alpha-Lipoic AcidALADIN Study (Ziegler 1995)
Alpha-Lipoic AcidALA glycemic meta-analysis 2021 (28 RCTs)
Alpha-Lipoic AcidALA inflammatory meta-analysis 2019 (41 studies)
Alpha-Lipoic AcidALA + T2D RCT 2022 (16 RCTs)
Important to know
Alpha-Lipoic AcidCheap 'ALA' products sell the racemic form (50% inactive). Look for 'R-ALA' or 'R-alpha-lipoic acid'. Take on empty stomach.

Editorial notes

A sustained-release 300mg alpha lipoic acid tablet co-formulated with biotin (not R-ALA-isolated), a reasonable mitochondrial/glutathione-support product, also sold as a 600mg SKU per the product line.

Go deeper

Where this sits

Actives inside
Alpha-Lipoic Acid
Category
See all in Mitochondrial →
Brand
Jarrow Formulas profile →
Add to compare Visit brand site →
Brand owners

Spot an error?

If you are the manufacturer or brand owner of Jarrow Formulas Alpha Lipoic Sustain with Biotin, 300 mg and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
Same shelf

Similar products

All Mitochondrial →

The next highest-scoring products in Mitochondrial, same scoring method, same rules.

Mitochondrial
Active per serving
Urolithin A 500 mgCapsule · 30 servings
Price per serving
$1.87$55.97 · 30 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 8.6/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$3.73
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.prohealth.com
Timeline Nutrition
Mitopure® Softgel
Mitochondrial
Active per serving
Urolithin A 500 mgSoftgel · 30 servings
Price per serving
$2.17$65.00 · 30 servings
Testing
3rd-party listed · no public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 8.6/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$4.33
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.timeline.com
Mitochondrial
Active per serving
Creatine 10 gPowder · 30 servings
Price per serving
$0.88$26.50 · 30 servings
Testing
3rd-party listed · no public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 8.6/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.44
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with donotage.org
Same maker

Other products from Jarrow Formulas

Brand profile →
Vitamin
Vitamin per serving
Vitamin D3 125 µgSoftgel · 100 servings
Price per serving
$0.13$12.74 · 100 servings
Testing
None listed

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 7.5/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.05
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with jarrow.com
Amino acid
Active per serving
NAC 600 mgTablet · 60 servings
Price per serving
$0.43$25.99 · 60 servings
Testing
None listed

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.9/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.43
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with jarrow.com
Methyl donor
Active per serving
Folate (5-MTHF) 400 µgCapsule · 60 servings
Price per serving
$0.20$11.99 · 60 servings
Testing
None listed

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.7/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.20
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with jarrow.com
Mitochondrial
Active per serving
CoQ10 100 mgSoftgel · 60 servings
Price per serving
$0.85$50.99 · 60 servings
Testing
None listed

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.6/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$1.70
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with jarrow.com
Omega
EPA and DHA per serving
EPA 800 mg · DHA 400 mgSoftgel · 60 servings
Price per serving
$1.02$61.33 · 60 servings
Testing
None listed

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.3/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

60%
of trial dose
$3.41
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with jarrow.com