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Layer 1 · Decision
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L-Ergothioneine - 25 mg, 30 capsules

Amino acid · Capsule · 30 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Active per serving
Ergothioneine 25 mg
Form
Capsule
List price (catalog, USD)
$39.95
Price per serving
$1.33List price divided by servings per container. A per-day cost only if the label serving is once daily.
Full label record: servings, testing, ingredients
Servings per container
30
Catalog monthly estimate
$39.95
Testing disclosure
Brand lists third-party testing and a public certificate of analysis (CoA)Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

IngredientAmount per serving
Ergothioneine25 mg

What to check on the label

  • The compound form (creatine monohydrate, NAC, glycine) and the grams per scoop or per capsule.
  • Scoop size versus the catalog serving. Some labels define a serving as two scoops.
  • Flavoured versions add sweeteners and fillers under 'other ingredients'.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

6.7/10
Overall score
#7 / 13 in Amino acid

Public lab certificate, tested by independent lab, top 10% value.

Read the evidence (2 studies)
Watch outEU restricted1 ingredient restricted in the EUYou can legally buy these outside the EU. Sale as a food supplement inside the EU requires a Novel Food authorisation these ingredients do not have.
Tier 4
Ingredient RCT (different dose)
The ingredient was tested in an RCT but at a different dose, or only in animals.
See the 2 supporting studies
How we scored this product Show the full breakdown
Composite How this 6.7 is built. 0.50 × 5.4 + 0.20 × 9.0 + 0.10 × 9.4 + 0.10 × 5.0 + 0.05 × 8.5 + 0.05 × 6.6 = 6.7 out of 10. Safety caps applied after. 6.7
6.7 composite
Dose vs. studies50%5.4
Transparency20%9.0
Value10%9.4
Formulation10%5.0
Safety5%8.5
Community5%6.6

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Editorial verdict

Quick verdict

6.7 / 10
Best for
Full trial dose, Public lab certificate
Avoid if
No major red flags
Full-dose status
Meets trial dose
Price/month
$40
COA status
Public
Biggest caveat
Dose-evidence score of 5.4 is below average for the site.
Nearest alternatives
Catalog snapshot. Check linked sources for current price, label and batch-specific testing.
Price verification
Current price: $39.95
Last price check: Sep 01, 2026
Layer 2 · Context
In plain language

Why this scored this way

This ProHealth Longevity L-Ergothioneine - 25 mg, 30 capsules scores 6.7, making it a mid-tier product with both strengths and weaknesses. It delivers 25mg of Ergothioneine, inside the studied range of 5–30mg with grade C evidence (mostly preclinical, limited human data). Transparency is a clear strength (score: 9.0), with third-party testing and a public lab certificate.

What drives the score up

  • Quality transparency of 9.0: tested by independent lab with a public lab certificate.

What drags it down

  • Dose-evidence score of 5.4 is below average for the site.
  • Ergothioneine (25.0mg is 250% of the 10mg trial dose) is well above the trial dose. More is not always better.

Why you'd choose it

  • You want good value at $0.53/day.
  • You prioritise tested by independent lab products with public lab certificates.

Why you might skip it

  • You want a standard dose of ergothioneine (this product is well above it).
Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Ergothioneine

A rare mushroom-derived amino acid that accumulates in tissues under oxidative stress, blood levels drop with age.

2 landmark RCTs · US: GRAS notice filed · EU: Novel food approved (2017)
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
100% of trial dose
Meets or exceeds the published effective dose
Cost at trial dose
$0.53/day at trial dose
What one effective daily dose actually costs
Transparency
9.0/10 · Public lab certificate (quality: not assessed)
Independent batch testing confirmed
Consumer signals
33 reviews across platforms · 2.9/5 · medium confidence
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

Buyer complaints
Trustpilot: shipping and order issues; Trustpilot: mixed product satisfaction
Recurring themes from consumer review platforms.
Plain English

What’s inside

The main ingredients of this product, in plain language.

Ergothioneine25 mgEvidence C

A rare mushroom-derived amino acid that accumulates in tissues under oxidative stress, blood levels drop with age.

Read about Ergothioneine →
Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price
$40
per bottle · 30 servings
Dose vs. research
of trial dose 100%
of published effective dose
$ / day at studied dose
$0.53
what one effective daily dose costs
$ / g active
$53.27
per gram of active substance
Independently checked

Data verification

COA status
Public
Evidence grade
C
Per-ingredient breakdown
CErgothioneine

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Evidence
Ergothioneine
A rare mushroom-derived amino acid that accumulates in tissues under oxidative stress, blood levels drop with age.
25 mg 250% of trial dose
10 mg
3.2 /5
Medium confidence
33 reviews across 4 platforms (4 sources)
Source diversity: 92%
AmazonRedditTrustpilotiHerb
Praiseresponsive customer serviceperceived cognitive/immune benefit
Complaintsshipping and order issuesmixed product satisfaction
Last checked: 2026-08-20

Consumer signals

2.89 out of 5 across 33 verified reviews on 4 platforms.

Medium confidence

Consumer sentiment compiled from 4 public sources.

25 reviews · 2.5/5 · mixed sentiment

Praiseresponsive customer service
Complaintsshipping and order issuesmixed product satisfaction
Themes

ProHealth Longevity's Trustpilot page shows a mixed reputation with some praising service and others citing order problems.

Compiled from Trustpilot listing located during research; verified at build time.

8 reviews · 4.1/5 · positive sentiment

Praiseperceived cognitive/immune benefitgood manufacturing quality
Complaintssmall review sample size
Themes

Early Amazon reviewers rate the ergothioneine capsules positively for perceived cognition and immune support, though the review base is still small.

Compiled from Amazon listing located during research; verified at build time.

positive sentiment

Praisehelps sleep and immunitygood capsule quality
Complaintslarge packaging for capsule count
Themes

iHerb reviewers report the supplement helps with sleep and immune support, with only minor complaints about oversized packaging.

Compiled from iHerb listing located during research; verified at build time.

4 threads discussed · mixed sentiment

Praiseinterest in longevity benefits
Complaintslimited long-term human evidence
Themes

Biohacker communities on Reddit discuss ergothioneine's longevity potential with curiosity but note the evidence base is still preliminary.

Compiled from Reddit listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Important to know
ErgothioneineSome products dose well below the 5 to 10 mg/day used in trials. Fermented (yeast-derived) sources are more sustainable but check purity/COA.

Editorial notes

A single-ingredient, relatively high-dose (25mg) ergothioneine capsule, a mitochondrial/antioxidant amino acid with growing longevity research interest; priced at the premium end (~$1.33/capsule) among competing ergothioneine products.

Brand owners

Spot an error?

If you are the manufacturer or brand owner of L-Ergothioneine - 25 mg, 30 capsules and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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