SuppCo is a separate, unaffiliated supplement-tracking site with no partnership, data-sharing agreement, or business relationship with NO1GEVITY. We are not endorsed by them and they do not endorse us. The two facts below are individually verified against the manufacturer or NSF; the outbound link is provided only so readers can independently cross-check on a third-party site if they want to.
Alpha Lipoic Acid 400 mg
Label snapshot
What the label says
What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.
- Active per serving
- Alpha-Lipoic Acid 400 mg
- Form
- Capsule
- List price (catalog, USD)
- $97.00
- Price per serving
- $0.81List price divided by servings per container. A per-day cost only if the label serving is once daily.
Full label record: servings, testing, ingredients
- Servings per container
- 120
- Catalog monthly estimate
- $24.25
- Testing disclosure
- No third-party testing listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Ingredients as listed
| Ingredient | Amount per serving |
|---|---|
| Alpha-Lipoic Acid | 400 mg |
What to check on the label
- Whether the milligrams describe the whole extract or the standardised compound (for example '500 mg turmeric extract' versus '475 mg curcuminoids').
- Delivery wording such as liposomal or phytosome changes the carrier, not the labelled amount.
- For glutathione and sulforaphane, check whether the label lists the compound itself or a precursor (glucoraphanin, NAC).
Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.
Editorial score and research-dose calculations
These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.
See the 3 supporting studies
- ALA + T2D RCT 2022 (16 RCTs) (Alpha-Lipoic Acid)In 16 RCTs (1,035 T2D patients), each 500 mg/day increase in ALA significantly reduced HbA1c, body weight, and CRP, though effect sizes were below clinically important thresholds. Studied at 500 mg. This product: 400 mg.
- ALADIN Study (Ziegler 1995) (Alpha-Lipoic Acid)In a 328-patient, 3-week RCT, intravenous alpha-lipoic acid (600 mg/day) significantly reduced diabetic peripheral neuropathy symptom scores versus placebo (63.5% vs 38.4% reduction). Studied at 600 mg. This product: 400 mg.
- ALA glycemic meta-analysis 2021 (28 RCTs) (Alpha-Lipoic Acid)Across 28 RCTs (1,016 participants), ALA supplementation significantly reduced insulin and HOMA-IR but had no significant effect on glucose or HbA1c.
How we scored this product Show the full breakdown
Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.
This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.
Quick verdict
Our summary
Why this scored this way
This Pure Encapsulations Alpha Lipoic Acid 400 mg scores 7.4, making it a mid-tier product with both strengths and weaknesses. It delivers 400mg of Alpha-Lipoic Acid, inside the studied range of 300–1200mg with grade A evidence (strong human trial data). The quality transparency (5.0) is limited by the lack of third-party testing.
What drives the score up
- Dose-evidence score of 9.0 reflects good alignment with trial doses.
- Alpha-Lipoic Acid is dosed at the full research level with grade A evidence (strong human trial data).
What drags it down
- No third-party testing, which caps the quality transparency.
- Quality transparency of 5.0 is below the site average.
Why you'd choose it
- You want a reasonably priced antioxidant product.
- You want Alpha-Lipoic Acid from a Pure Encapsulations product.
- You want doses that align with published research.
Why you might skip it
- You want third-party verified purity.
- You want a product with a publicly available CoA.
- You want better value (this is $1.21/day with a value score of 8.4).
Question 1
Does the molecule work?
Does the molecule work?
The science behind each active ingredient, independent of which brand sells it.
Mitochondrial cofactor with genuine efficacy in diabetic neuropathy.
Question 2
Is this bottle good?
Is this bottle good?
The specific product: dose, price, transparency, and what buyers report.
Question 3
What's the catch?
What's the catch?
Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.
What’s inside
The main ingredients of this product, in plain language.
Mitochondrial cofactor with genuine efficacy in diabetic neuropathy.
Read about Alpha-Lipoic Acid →Product data & verification
Hard numbers and independently checked status. Expand each block for its source.
The numbers
Data verification
Per-ingredient breakdown
All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.
What's inside
Consumer signals
Consumer signals gathered from 5 platforms.
Low confidence, small sampleConsumer sentiment compiled from 4 public sources; most Trustpilot data reflects brand-level rather than product-specific feedback.
8 reviews · 2.4/5 · mixed sentiment
Trustpilot score reflects the brand overall, not this specific product; scores skew low despite product-level praise elsewhere.
Compiled from Trustpilot listing located during research; verified at build time.
positive sentiment
Buyers report better energy and clarity, with mild urine odor as the main complaint.
Compiled from Amazon listing located during research; verified at build time.
positive sentiment
iHerb reviewers highlight relief from nerve pain and fast, reliable delivery.
Compiled from iHerb listing located during research; verified at build time.
2 threads discussed · mixed sentiment
Reddit threads on ALA for neuropathy show some users reporting relief, though effectiveness is debated generally for the ingredient.
Compiled from Reddit listing located during research; verified at build time.
1 thread discussed · positive sentiment
used specifically for nerve-pain symptom relief rather than general antioxidant support
anecdotal improvement reported over a period of weeks, not immediate
These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.
Independent external anchors
Public sources on this same product, unrelated to NO1GEVITY. NIH DSLD is the US government's registered label database (shown verbatim). SuppCo.com is a separate, unaffiliated commercial site with no partnership or data-sharing arrangement with us. NO1GEVITY scores are computed independently of both.
What others say (unverified)
No external reviews aggregated yet for this product.
Evidence, claims & regulation
Published evidence, claim checks, regulatory status and what could not be verified.
Evidence, what actually backs this product
Longevity brands rarely test their exact finished product. We separate what's tested from what's inferred.
Research behind this product
The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.
Claim check, vendor claims vs. our reading of the evidence
Not medical advice. We list the strongest claims made by the brand and check each against traceable evidence.
Regulatory status
Rules change often. We record when we last verified each row. See the full regulatory timeline →
What we could not verify
We list this openly. If a claim isn't backed by a source we can trace, we'd rather flag it than repeat it.
- No public Certificate of Analysis or independent third-party lab test was found for this specific SKU.
- No RCT was located using this exact oral 400 mg capsule as the study material.
- The vendor's suggested-use range (1-4 capsules/day) spans a fourfold dose difference, and the label does not specify which dose within that range is supported by which cited outcome.
- The strongest positive neuropathy trial (ALADIN) used intravenous administration; oral bioavailability of ALA is known to be lower and more variable, so this trial should not be read as direct evidence for this oral product.
Editorial notes
A single-ingredient 400mg ALA capsule at the pricier end (~$0.81-1.62/day) versus the brand's own 100/200/600mg tiers, mid-range dose within ALA's typical 100-1200mg/day research range for glucose/nerve support.
Where this sits
Spot an error?
If you are the manufacturer or brand owner of Alpha Lipoic Acid 400 mg and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.
We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.
Request a correction →Similar products
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