What is CoQ10 (formerly Q-Best 100)?

CoQ10 (formerly Q-Best 100) is a Mitochondrial supplement by Thorne HealthTech. NO1GEVITY gives it a overall score of 6.4 out of 10.

How much does CoQ10 (formerly Q-Best 100) cost?

$46.00 for 60 servings. Cost per day at the studied dose is $1.53.

Is CoQ10 (formerly Q-Best 100) tested by independent lab?

Yes, tested by independent lab. No public lab certificate.

What is the NO1GEVITY score for CoQ10 (formerly Q-Best 100)?

CoQ10 (formerly Q-Best 100) scores 6.4/10 on the NO1GEVITY composite scale, based on evidence-graded dose (100% of trial dose), transparency, value, consumer signals, and formulation.

Does CoQ10 (formerly Q-Best 100) match the dose used in clinical studies?

CoQ10 (formerly Q-Best 100) delivers 100% of the dose used in clinical research, which is at or above the studied dose.

What is the evidence for CoQ10?

CoQ10 is graded B on the NO1GEVITY evidence scale, meaning moderate human evidence from multiple RCTs.

What do consumers say about CoQ10 (formerly Q-Best 100)?

Across 42 verified consumer reviews aggregated by NO1GEVITY, CoQ10 (formerly Q-Best 100) averages 3.8 out of 5. Sources include Trustpilot, Amazon, iHerb and Labdoor where available.

Layer 1 · Decision

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Thorne HealthTech

CoQ10 (formerly Q-Best 100)

Name: CoQ10 (formerly Q-Best 100)
Brand: Thorne HealthTech
SKU: thorne-coq10
Price: 46.0 USD
Availability: InStock
Rating: 3.8 (42 reviews)

Mitochondrial · Softgel · 60 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Active per serving: CoQ10 100 mg
Form: Softgel
List price (catalog, USD): $46.00
Price per serving: $0.77List price divided by servings per container. A per-day cost only if the label serving is once daily.

Full label record: servings, testing, ingredients

Servings per container: 60
Catalog monthly estimate: $23.00
Testing disclosure: Brand lists third-party testing; no public lab certificate listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

Ingredient	Amount per serving
CoQ10	100 mg

What to check on the label

Which form of the compound the label names (for CoQ10: ubiquinol or ubiquinone) and whether the milligrams refer to that form.
Softgel oil carriers are listed under 'other ingredients'. They are not part of the active amount.
Branded ingredients (Mitopure, BioPQQ and similar) should be named on the label if the brand claims them.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

6.4/10

Overall score

#22 / 30 in Mitochondrial

Tested by independent lab.

Read the evidence (1 study)

Add to compare Visit brand site →

Watch outEU restricted

Tier 4

Ingredient RCT (different dose)

The ingredient was tested in an RCT but at a different dose, or only in animals.

See the 1 supporting study

Q-SYMBIO 2014 (Mortensen et al., JACC) (CoQ10)300 mg/day in chronic HF cut major cardiovascular events 43% over 2 years. Studied at 300 mg. This product: 100 mg.

How we scored this product Show the full breakdown

Dose vs. studies (50%) 7.2

Transparency (20%) 7.0

Value (10%) 8.0

Formulation (10%) 8.0

Safety (5%) 7.0

Community sentiment (5%) 5.0

Composite 6.4

6.4 composite

Dose vs. studies50%7.2

Transparency20%7.0

Value10%8.0

Formulation10%8.0

Safety5%7.0

Community5%5.0

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Best for

Full trial dose, Budget-friendly

Avoid if

No public lab certificate

Full-dose status

Meets trial dose

Price/month

$23

COA status

Not public

Biggest caveat

No public lab certificate available for independent verification.

Nearest alternatives

Ultimate Omega +CoQ10 Nordic Naturals · Score 7.7
CoQH-CF Softgels | Ubiquinol Supplement Nootropics Depot · Score 7.4
Nordic CoQ10 Ubiquinol Nordic Naturals · Score 7.3

Catalog snapshot. Check linked sources for current price, label and batch-specific testing.

Price verification

Current price: $46.00

Last price check: Sep 01, 2026

Add to compare Visit brand site →

Layer 2 · Context

Our summary

Thorne's CoQ10 delivers a standard 100 mg ubiquinone dose with several lipophilic additives (flaxseed oil, lycopene, turmeric, CLA) marketed as absorption enhancers, though no dedicated trial tests that specific combination. The best outcomes evidence for ubiquinone CoQ10 (the Q-SYMBIO heart-failure trial) used three times this product's per-softgel dose in a severely ill population, and the widely repeated statin-myalgia benefit is contradicted by multiple independent meta-analyses. This is a competently formulated, standard-form CoQ10 product, but its 'optimally absorbed' positioning is a plausible, untested formulation choice rather than a proven bioavailability advantage.

In plain language

Why this scored this way

This Thorne HealthTech CoQ10 (formerly Q-Best 100) scores 7.2, making it a mid-tier product with both strengths and weaknesses. It delivers 100mg of CoQ10, inside the studied range of 100–300mg with grade B evidence (promising human data, not yet comprehensive). At $1.53/day it's among the more expensive options in Mitochondrial.

What drives the score up

Dose-evidence score of 7.2 shows decent alignment with trial doses.
Tested by independent lab (transparency 7.0).
CoQ10 is dosed at the full research level with grade B evidence (promising human data, not yet comprehensive).

What drags it down

No public lab certificate available for independent verification.
Limited consumer feedback (community score: 5.0).
At $1.53/day it's on the expensive side.

Why you'd choose it

You want a reasonably priced mitochondrial product.
You want CoQ10 from a Thorne HealthTech product.
You want a tested by independent lab product.

Why you might skip it

You want a product with a publicly available CoA.
You want a cheaper option (this is $1.53/day).
You prefer products with substantial consumer feedback.

Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

CoQ10

A well-established mitochondrial cofactor, especially useful on statins.

1 landmark RCT · US: Dietary supplement · EU: Food supplement, no Novel Food status needed

Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research

100% of trial dose

Meets or exceeds the published effective dose

Cost at trial dose

$1.53/day at trial dose

What one effective daily dose actually costs

Transparency

7.0/10 · No public lab certificate

Independent batch testing confirmed

Consumer signals

42 reviews across platforms · 3.8/5 · medium confidence

Operational signal only, never used as clinical evidence

Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

Review advised

coq10: warfarin/anticoagulant interaction

Safety flag

coq10: warfarin/anticoagulant interaction

Dose or interaction risk detected. See ingredient page for details.

No public lab certificate

Certificate of Analysis not published

Without a public lab certificate, batch purity and potency cannot be independently verified.

Buyer complaints

Trustpilot: unresponsive customer service; Trustpilot: shipping delays and order issues

Recurring themes from consumer review platforms.

Plain English

What’s inside

The main ingredients of this product, in plain language.

CoQ10100 mgEvidence B

A well-established mitochondrial cofactor, especially useful on statins.

Read about CoQ10 →

Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price

$46

per bottle · 60 servings

Dose vs. research

of trial dose 100%

of published effective dose

$ / day at studied dose

$1.53

what one effective daily dose costs

$ / g active

$7.67

per gram of active substance

Independently checked

Data verification

COA status

Not public

Evidence grade

Per-ingredient breakdown

BCoQ10

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient

Dose in this product

Trial dose

Evidence

CoQ10

A well-established mitochondrial cofactor, especially useful on statins.

Q-SYMBIO 2014 (Mortensen et al., JACC)

100 mg 50% of trial dose

200 mg

2.2 /5

High confidence Price exceeds satisfaction

77 reviews across 4 platforms (5 sources)

Source diversity: 100%

AmazonRedditTrustpilotiHerb

Praisehelps ease heart palpitationshigh quality product

Complaintsunresponsive customer serviceshipping delays and order issues

Last checked: 2026-08-20

Consumer signals

3.8 out of 5 across 42 verified reviews on 5 platforms.

Medium confidence

Consumer sentiment compiled from 4 public sources.

Trustpilot

42 reviews · 2.4/5 · negative sentiment

Complaintsunresponsive customer serviceshipping delays and order issues

Themes

Thorne's brand-level Trustpilot rating remains poor, dominated by customer-service and shipping complaints.

Compiled from Trustpilot listing located during research; verified at build time.

Amazon

positive sentiment

Praisehelps ease heart palpitationshigh quality product

Themes

Amazon reviewers report Thorne's CoQ10-containing formula helps with heart palpitations and is high quality.

Compiled from Amazon listing located during research; verified at build time.

iHerb

positive sentiment

Praiseexceptional quality and absorptionhighly recommended

Themes

iHerb reviewers consistently rate this product's quality and absorption very highly.

Compiled from iHerb listing located during research; verified at build time.

4 threads discussed · positive sentiment

Praiserecommended for optimal absorption and third-party testingused in IVF protocols

Complaintsconsidered pricier than some alternatives

Themes

Reddit users, including in IVF-focused communities, highly recommend Thorne's CoQ10 for its absorption and purity testing despite a higher price.

Compiled from Reddit listing located during research; verified at build time.

Same brand profile on Trustpilot country sites: US 1.8.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

Independent external anchors

Public sources on this same product, unrelated to NO1GEVITY. NIH DSLD is the US government's registered label database (shown verbatim). SuppCo.com is a separate, unaffiliated commercial site with no partnership or data-sharing arrangement with us. NO1GEVITY scores are computed independently of both.

Unaffiliated third-party site

SuppCo.com

SuppCo is a separate, unaffiliated supplement-tracking site with no partnership, data-sharing agreement, or business relationship with NO1GEVITY. We are not endorsed by them and they do not endorse us. The two facts below are individually verified against the manufacturer or NSF; the outbound link is provided only so readers can independently cross-check on a third-party site if they want to.

NIH DSLD registered label

DSLD ID 182608, UPC 6 93749 62401 1

Serving size1 Gelcap(s)

Servings per containern/a

Supplement Facts panel, verbatim

Calories10 Calorie(s)

Total Fat1 Gram(s)1% DV

Protein0.5 Gram(s)1% DV

Coenzyme Q10100 mg

What others say (unverified)

No external reviews aggregated yet for this product.

Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence, what actually backs this product

Longevity brands rarely test their exact finished product. We separate what's tested from what's inferred.

Strongest evidence tier

Tier 4Ingredient RCT (different dose)

4 studies mapped

Tier 4Ingredient RCT (different dose)

The Effect of Coenzyme Q10 on Morbidity and Mortality in Chronic Heart Failure: Results From Q-SYMBIO: A Randomized Double-Blind Trial

Mortensen SA, Rosenfeldt F, Kumar A, et al. (Q-SYMBIO Study Investigators) · 2014 · JACC: Heart Failure · n=420 · 100 mg CoQ10 (ubiquinone) three times daily (300 mg/day total) · 2 years (106 weeks median follow-up)

ingredient-levelpeer-reviewed

CoQ10 added to standard heart-failure therapy reduced major adverse cardiovascular events by 43% (15% vs. 26%, HR 0.50, p=0.003), cardiovascular mortality by ~43% (9% vs. 16%, p=0.026), and all-cause mortality by ~42% (10% vs. 18%, p=0.018/0.036) versus placebo.

The single most important CoQ10 outcomes trial, using the same ubiquinone (oxidized) form as Thorne's product but at 300 mg/day split into three 100 mg doses, 3x this product's per-softgel dose, requiring three softgels/day to match. Studied in severe heart-failure patients, not general wellness consumers; ACC/AHA guidelines still do not recommend CoQ10 as standard HFrEF therapy despite this result, citing small absolute event numbers.

Conflicts: Funded/supported by the International Coenzyme Q10 Association and CoQ10 manufacturers Pharma Nord and Kaneka Corporation

Source →

Tier 4Ingredient RCT (different dose)

Effects of Coenzyme Q10 on Statin-Induced Myopathy: An Updated Meta-Analysis of Randomized Controlled Trials

Qu H, Guo M, Chai H, et al. · 2018 · Journal of the American Heart Association · n=575 · 100-600 mg/day CoQ10 (mixed ubiquinone/ubiquinol trials), 30 days to 3 months · 30 days to 3 months across pooled trials

ingredient-levelpeer-reviewed

Pooled analysis found CoQ10 supplementation significantly reduced statin-associated muscle pain, weakness, cramps, and tiredness versus placebo, though plasma creatine kinase levels were unchanged.

Contradicts an earlier 2015 Mayo Clinic Proceedings meta-analysis (6 studies, n=302) that found no significant effect, and a 2020 Atherosclerosis meta-analysis (7 RCTs, n=321) that also found no benefit, the statin-myalgia literature is genuinely mixed. Not specific to this 100 mg ubiquinone product.

Conflicts: None identified

Source →

Tier 5Mechanistic / animal / marketing

Effects of coenzyme Q10 on statin-induced myopathy: a meta-analysis of randomized controlled trials

Banach M, Serban C, Sahebkar A, et al. · 2015 · Mayo Clinic Proceedings · n=302 · Varied CoQ10 doses across pooled trials · Varied across pooled trials

ingredient-levelpeer-reviewed

No significant effect of CoQ10 on plasma creatine kinase or on muscle pain versus placebo, despite a non-significant trend toward pain reduction.

Cited to document the mixed statin-myalgia evidence base honestly, directly contradicting the 2018 Qu et al. meta-analysis above.

Conflicts: None identified

Source →

Tier 5Mechanistic / animal / marketing

Bioavailability of Coenzyme Q10: An Overview of the Absorption Process and Subsequent Metabolism

Mantle D, Dybring A · 2020 · Antioxidants (MDPI) · Varied across reviewed studies (100-200 mg single or repeated doses) · N/A

ingredient-levelpeer-reviewed

Concludes that formulation factors (crystal dispersion, carrier oil, solubilization) affect CoQ10 bioavailability far more than whether the ingested form is ubiquinone or ubiquinol, stating the idea of ubiquinol's inherent superiority 'would appear to be mistaken.'

Directly relevant to Thorne's marketing angle, which emphasizes absorption enhancers (flaxseed oil, lycopene, CLA) rather than switching to ubiquinol, this review supports the general premise that delivery-vehicle formulation matters more than raw ubiquinone-vs-ubiquinol chemistry, though it doesn't test Thorne's specific additive combination.

Conflicts: None identified

Source →

Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

CoQ10 Q-SYMBIO 2014 (Mortensen et al., JACC)

Claim check, vendor claims vs. our reading of the evidence

Not medical advice. We list the strongest claims made by the brand and check each against traceable evidence.

Unverifiable

“Optimally absorbed CoQ10 formulation via added flaxseed oil, lycopene, turmeric, and CLA”

There is a real, independent-review-supported premise that delivery-vehicle formulation (oil-based carriers, particle size) affects CoQ10 absorption more than the ubiquinone-vs-ubiquinol distinction (https://pmc.ncbi.nlm.nih.gov/articles/PMC7278738/). However, no dedicated pharmacokinetic study was located testing Thorne's specific combination of flaxseed oil, lycopene, turmeric, and CLA against a plain ubiquinone softgel, so the 'optimally absorbed' framing rests on a plausible but untested formulation choice, not a head-to-head bioavailability trial.

Vendor source

Partial support

“Standard ubiquinone form (as opposed to ubiquinol) is an adequate, effective CoQ10 form (implicit in Thorne's product choice; the company also does not sell a ubiquinol version under this name)”

Evidence is genuinely split: a 2020 independent review concludes ubiquinol's presumed bioavailability superiority 'would appear to be mistaken' (https://pmc.ncbi.nlm.nih.gov/articles/PMC7278738/), while a small 2018 crossover RCT in older men (n=10) found ubiquinol raised plasma CoQ10 status 1.5-fold more than ubiquinone (https://pubs.rsc.org/en/content/getauthorversionpdf/c8fo00971f). Thorne's ubiquinone choice is defensible but not definitively superior or inferior based on current evidence.

Vendor source

Regulatory status

Rules change often. We record when we last verified each row. See the full regulatory timeline →

What we could not verify

We list this openly. If a claim isn't backed by a source we can trace, we'd rather flag it than repeat it.

No dedicated bioavailability study was located testing Thorne's specific absorption-enhancer additive blend (flaxseed oil, lycopene, turmeric, CLA) against plain ubiquinone CoQ10.
No public per-batch Certificate of Analysis was located for this SKU despite Thorne's facility-level NSF certification.
No RCT was located using this exact branded product; all outcome evidence is at the ubiquinone-ingredient level, mostly at higher doses (300 mg/day) than this product's single-softgel dose (100 mg).
The statin-myalgia benefit claim commonly associated with CoQ10 is contradicted by at least two independent meta-analyses, a nuance not disclosed on Thorne's retail page.

Important to know

CoQ10Cheap CoQ10 powder in capsules has minimal absorption. Look for softgels with oil carrier or ubiquinol form.

Editorial notes

Standard ubiquinone CoQ10 at a common 100mg dose; ubiquinol forms (e.g. competitors' Q10) generally absorb better in adults over 40, which this product does not use.

Go deeper

Where this sits

Actives inside

CoQ10

Spot an error?

If you are the manufacturer or brand owner of CoQ10 (formerly Q-Best 100) and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →

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CoQ10 (formerly Q-Best 100)

What the label says

Ingredients as listed

What to check on the label

Quick verdict

Our summary

Why this scored this way

What drives the score up

What drags it down

Why you'd choose it

Why you might skip it

Does the molecule work?

Is this bottle good?

What's the catch?

What’s inside

Product data & verification

The numbers

Data verification

What's inside

Consumer signals

Independent external anchors

What others say (unverified)

Evidence, claims & regulation

Evidence, what actually backs this product

Research behind this product

Claim check, vendor claims vs. our reading of the evidence

Regulatory status

What we could not verify

Editorial notes

Where this sits

Spot an error?

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