Study

Fisetin is a senotherapeutic that extends health and lifespan

Yousefzadeh MJ et al.

PRIMARY 2018
Summary Can fisetin slow aging and help animals live longer? Show / hide ↓

Researchers tested fisetin, a plant compound, in aging mice and laboratory cells. They gave old mice occasional doses and compared them with untreated mice. Fisetin reduced signs of senescent cells, which are damaged cells that stop working normally and release harmful signals. The treated mice stayed healthier and lived about 36% longer on average. This study did not test people.

What this means for you: This does not show that fisetin supplements help humans live longer, and the effective mouse dose may not translate safely to people. Do not buy fisetin for longevity based on this study alone.

early evidence
DesignPRIMARY
TierTier 4, Ingredient RCT (different dose)
Year2018
JournalEBioMedicine
Added to NO1GEVITYMay 7, 2026

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