mTOR as a central regulator of lifespan and aging

Researchers reviewed evidence about mTOR, a protein system that helps cells respond to food and growth signals. They examined findings from laboratory cells, animals, and some human research, rather than testing one treatment in a group of people. In animals, reducing mTOR activity or using rapamycin, a drug that blocks part of this system, often extended lifespan. The effects in humans remain uncertain, and rapamycin can cause harmful side effects.

What this means for you: This does not show that buying an mTOR supplement or taking rapamycin will help you live longer. The findings are useful for research, but they do not yet justify using these treatments for healthy people outside medical studies.