Effect of Vitamin K on Bone Mineral Density and Fracture Risk in Adults: Systematic Review and Meta-Analysis

This systematic review and meta-analysis combined results from many studies of vitamin K supplements in adults. Researchers examined bone mineral density, a measure of how much mineral is packed into bone, and whether participants had broken bones. Vitamin K was linked with small improvements in bone density in some areas, especially the lower spine, but results varied. The evidence that vitamin K prevents fractures remained uncertain because the studies used different doses, types of vitamin K, and participants.

What this means for you: This is not strong evidence to buy vitamin K solely to prevent fractures. It may help bone density in some situations, but proven fracture prevention remains uncertain. People taking warfarin or similar blood thinners should ask a clinician before changing their vitamin K intake.