FOXO3A genotype is strongly associated with human longevity

Researchers studied Japanese-American men in Hawaii who had been followed for many years. They compared men who lived to at least 95 with men who died at younger ages. They looked at small DNA differences in FOXO3A, a gene involved in how cells handle stress and aging. Men with certain versions of this gene, especially two copies of one version, were more likely to reach very old age.

What this means for you: This suggests that inherited genes may affect the chances of living a long life, but they are only one part of the picture. It does not support buying a supplement or genetic test to extend your life, and the results may not apply equally to women or other ethnic groups.