Study

Bryan Johnson and Kate Tolo publicise a female-health measurement protocol

Zak Jason

TWO-PERSON N=2 PLANNED BIOMARKER AND SAUNA-TELEMETRY EXPERIMENT; NO RESULTS REPORTED 2026

NEW PUBLIC EXPERIMENT: Johnson and Kate Tolo describe a female-health measurement programme using about 50 devices and 30 apps, plus a planned two-person sauna pill test; no outcome data are reported.

DesignTWO-PERSON N=2 PLANNED BIOMARKER AND SAUNA-TELEMETRY EXPERIMENT; NO RESULTS REPORTED
TierTier 2, Product RCT (not peer-reviewed)
Year2026
JournalBusiness Insider
N2
PublishedSep 14, 2026
Added to NO1GEVITYSep 16, 2026

Business Insider’s 14 September 2026 report describes Kate Tolo, Blueprint cofounder and Johnson’s partner, starting a large personal measurement programme after an endometriosis diagnosis. The article says the plan uses about 50 devices and 30 apps to track variables such as pain tolerance, reaction time, grip strength, vaginal wetness, cortisol, oral microbiome, metabolic rate and menstrual-cycle data. The stated aim is to build a detailed biological record across four cycles and inform women’s-health research. The article also says the couple and their medical team planned a two-person sauna test: each would swallow a Bluetooth-connected pill and enter a 200°F sauna while the pills measured internal temperature. No protocol registration, prespecified endpoints, assay validation, control condition, sample-size justification, results, adverse events or peer-reviewed analysis is supplied. The article describes a planned public experiment, not evidence that the protocol treats endometriosis, improves fertility or extends life. Johnson’s involvement also creates a direct commercial and promotional interest because Blueprint and related companies sell health products and protocol access. This record therefore labels the report as an n=2 plan with no outcome evidence, not as a clinical trial.

No single scientific conclusion is reported; the article describes a planned public experiment and says no results are yet available.
Critic notes

The report notes that critics question what can be learned from one woman and from an extremely broad, uncontrolled measurement programme. No human RCT or meta-analysis found this week justifies an ingredient-grade upgrade.

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