Study

The Hallmarks of Aging

López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G

PRIMARY 2013
Summary What biological processes seem to drive aging, and can they be changed? Show / hide ↓

Researchers reviewed many earlier studies and proposed nine “hallmarks,” meaning biological changes that commonly appear as bodies age. These included DNA damage, shortening telomeres that protect chromosome ends, poorer energy production in cells, and a buildup of worn-out cells. No people or animals took part in this paper, and it did not test a treatment. It organized existing evidence into a framework for studying why aging happens.

What this means for you: This is a useful map of aging research, not proof that any supplement or treatment can slow aging. You can use it to understand research claims, but it does not by itself justify buying an anti-aging product.

moderate evidence
DesignPRIMARY
TierTier 5, Mechanistic / animal / marketing
Year2013
JournalCell
Added to NO1GEVITYMay 20, 2026

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