CALERIE biobank epigenetic aging analysis

Researchers studied stored blood samples from 218 healthy adults in a two-year calorie-reduction trial. Some people were asked to eat about 25% fewer calories, while others continued their usual diets. The researchers measured DNA methylation, chemical tags that help control how genes work, and used these tags to estimate biological age. Calorie restriction changed some aging-related tags, but it did not clearly slow the main measures of biological aging.

What this means for you: This does not show that calorie restriction makes people biologically younger. It is not a reason to buy an anti-aging product or sharply cut calories, especially since the measures were indirect and the study lasted only two years.