Study

Transient Epigenetic Reprogramming: The Future of Skin Rejuvenation

Menon GK, Monteleon C, Rhodes LV, Sebastiano V, Hsia HC

PRIMARY 2024
Summary Can briefly resetting skin cells make them act younger? Show / hide ↓

Researchers tested temporary epigenetic reprogramming, a short-term reset of cells’ activity settings, in human skin cells grown in a laboratory. The cells showed some younger-looking molecular patterns and improved signs of skin-cell function. No people received this treatment, and the study did not show that it reduces wrinkles or safely rejuvenates skin in humans. Longer-term risks, including unwanted cell growth, remain unknown.

What this means for you: This is promising laboratory research, not a proven skin treatment. You can ignore products claiming to offer this kind of reprogramming until human studies show that it works and is safe.

early evidence
DesignPRIMARY
TierTier 3, Ingredient RCT (matching dose)
Year2024
JournalDermatologic Surgery (PubMed)
Added to NO1GEVITYMay 30, 2026

Read the source

Cited by

1 encyclopedia entries reference this study.