Bryan Johnson took a transplant drug to live longer, then the side effects changed his mind

This was a self-experiment, not a controlled clinical trial. One healthy adult took rapamycin, a transplant drug that suppresses the immune system, hoping it would slow aging. The drug caused side effects, including mouth sores and other health problems, so he stopped taking it. There was no comparison group, and the experiment could not show whether rapamycin extended his life.

What this means for you: Do not take rapamycin for longevity based on this report. It requires a prescription, has real risks, and has not been proven to help healthy people live longer.