Study
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
Summary Can rapamycin help fruit flies live longer, and how might it work? Show / hide ↓
Researchers fed adult fruit flies different amounts of rapamycin and tracked how long they lived. Rapamycin extended their lives by about 14%. It reduced TOR, a cell-growth control system, and increased autophagy, the cells’ cleanup and recycling process. The treated flies handled starvation and oxidative stress, a type of cell damage, better, but handled heat stress worse. They also had fewer offspring, although this did not fully explain the longer lives.
What this means for you: This is an interesting result in fruit flies, not proof that rapamycin extends human life. You can ignore this as a reason to buy or take rapamycin, which can have important side effects and should only be used under medical supervision.
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