Ergothioneine: an underrecognised dietary micronutrient required for healthy ageing?

Researchers reviewed existing research on ergothioneine, a natural substance found mainly in mushrooms and some other foods. They examined how the body absorbs it and whether it may protect cells from damage linked with ageing. The evidence included laboratory work, animal studies, and human observational studies, which look for links but cannot prove cause and effect. The paper did not provide a new human trial showing that ergothioneine supplements improve health or extend life.

What this means for you: This is not strong evidence that you need an ergothioneine supplement. Eating mushrooms as part of a balanced diet is reasonable, but there is not enough proof to buy supplements for healthy ageing.