Study

Utility of coronary artery calcium scoring in low-risk patients: The Multi-Ethnic Study of Atherosclerosis (MESA)

Davis JR, Razavi AC, Ellberg CC, et al.

PRIMARY 2025
Summary Should low-risk people get a calcium scan to guide heart prevention? Show / hide ↓

Researchers analyzed 6,814 adults aged 45 to 84 who had no known heart disease. They used a CT scan to measure coronary artery calcium, hardened buildup in the heart’s blood vessels. Participants were followed for heart attacks, strokes, and other heart-related problems. People with no calcium generally had a low risk, while higher calcium levels identified people more likely to have problems. The study was observational, meaning the researchers found patterns but did not assign people to get scans or treatments.

What this means for you: This does not support routine calcium scans for everyone considered low risk. A scan may help when you and a clinician are unsure about preventive treatment, but the study does not show that scanning itself prevents heart problems.

moderate evidence
DesignPRIMARY
TierTier 2, Product RCT (not peer-reviewed)
Year2025
JournalAmerican journal of preventive cardiology
Added to NO1GEVITYJun 4, 2026

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