Study
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
PRIMARY
2003
Summary Can certain plant chemicals help yeast cells live longer? Show / hide ↓
Researchers tested resveratrol and other small chemicals on purified sirtuins, proteins involved in cell aging. They also gave the chemicals to yeast cells, a type of fungus used in laboratory aging studies. The treated yeast cells produced new cells for up to 70% longer than untreated cells. This effect depended on Sir2, a yeast sirtuin protein.
What this means for you: This was a yeast study, not a human study, so it does not show that resveratrol supplements or similar products extend human life. You can ignore this as a reason to buy a supplement.
early evidenceDesignPRIMARY
TierTier 3, Ingredient RCT (matching dose)
Year2003
JournalNature
Added to NO1GEVITYJun 9, 2026
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