Study

Supplementing GlyNAC in aging improves glutathione, mitochondria, and aging hallmarks: a randomized clinical trial

Kumar P, Liu C, Hsu JW et al.

RCT 2022
Summary Can a glycine and NAC supplement improve health measures in older adults? Show / hide ↓

Researchers randomly gave 24 older adults either GlyNAC or an inactive placebo. GlyNAC combines glycine and N-acetylcysteine, substances the body uses to make glutathione, an antioxidant that helps protect cells. Compared with the placebo, GlyNAC increased glutathione and improved several measures linked to cell energy production, inflammation, blood-sugar control, muscle strength, walking ability, and thinking. The study was small and lasted only a limited time, so it could not show whether GlyNAC slows aging or helps people live longer.

What this means for you: This is promising but preliminary evidence, not a reason to buy GlyNAC as an anti-aging treatment. Larger and longer studies are needed before its benefits and safety are clear.

early evidence
DesignRCT
TierTier 3, Ingredient RCT (matching dose)
Year2022
JournalClin Transl Med (extended follow-up/withdrawal data)
Added to NO1GEVITYJun 17, 2026

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