Study

Resveratrol and immunomodulation: tabular summary of human trial endpoints

Frontiers in Immunology editorial board

TABULAR REVIEW OF RESVERATROL EFFECTS ON IMMUNE AND INFLAMMATORY ENDPOINTS ACROSS HUMAN STUDIES 2026

A tabular review of resveratrol's inflammatory and immune endpoints across published human studies.

Summary Does resveratrol improve inflammation or immune health in people? Show / hide ↓

Researchers reviewed published human trials of resveratrol, a compound found in grapes and red wine. They compared changes in inflammation markers, which are blood signs of immune activity, across different studies. Some studies found small drops in CRP, a blood marker linked with inflammation, and TNF-alpha, an immune-system chemical, especially in people with metabolic problems. Results were mixed in healthy adults, and resveratrol did not clearly reduce infections. This was a review, not a new trial, so it added no new participants.

What this means for you: This review does not show that resveratrol supplements reliably improve health or prevent infections. You can ignore marketing claims unless better, larger studies show clear benefits.

conflicting evidence
DesignTABULAR REVIEW OF RESVERATROL EFFECTS ON IMMUNE AND INFLAMMATORY ENDPOINTS ACROSS HUMAN STUDIES
TierTier 3, Ingredient RCT (matching dose)
Year2026
JournalFrontiers in Immunology
PublishedJan 14, 2026
Added to NO1GEVITYJun 28, 2026

This is a table-heavy review of what resveratrol has actually done to inflammatory markers and immune endpoints in human trials. The recurring signals are modest reductions in CRP and TNF-alpha in metabolic populations, mixed effects in healthy adults, and no clear effect on infection incidence. Useful mainly as a reference for someone trying to reconcile positive-vs-null endpoints across studies.

Resveratrol's inflammatory endpoint effects are consistent in metabolic subgroups and inconsistent in healthy adults.
Critic notes

Not a formal meta-analysis. The table combines primary and secondary endpoints across studies of very different design.

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