Study
Spermidine for the Prevention of Radiation-Induced Xerostomia in Head and Neck Cancer (NCT07035626) — registration only, no results
Registered spermidine xerostomia trial NCT07035626 is still recruiting, N=58 estimated, no results have been posted.
Summary Can spermidine prevent dry mouth caused by cancer radiation treatment? Show / hide ↓
Researchers planned a randomized trial, meaning people are assigned by chance, to test whether spermidine can prevent xerostomia, or dry mouth, during radiation treatment for head and neck cancer. The study plans to include 58 people. It began on June 25, 2025, and is still recruiting participants. No results have been reported, so we do not know whether spermidine helps.
What this means for you: This study gives no reason to buy or take spermidine for radiation-related dry mouth yet. You can ignore claims that this trial already showed a benefit.
weak evidenceThis is a registered trial only. Xingchen Peng at West China Hospital registered a spermidine trial for prevention of radiation-induced dry mouth in head and neck cancer patients. Enrollment 58, estimated. Study started 2025-06-25 and the registry status is still RECRUITING. No resultsSection exists on ClinicalTrials.gov. Any percentages circulating for spermidine effect on dry mouth do not come from this trial. This record is included only to prevent citation confusion.
No results have been reported.
Do not cite outcome numbers for this trial. Wait for results publication.
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3 encyclopedia entries reference this study.