Role of autophagy in aging: The good, the bad, and the ugly

Researchers reviewed existing studies on autophagy, the cell’s natural recycling and cleanup system. They examined research in people, animals, and laboratory cells. The review found that autophagy can help maintain healthy cells in some situations, but may also have harmful effects in others, especially during disease. It did not test a treatment or follow a new group of people, so it cannot show that fasting, supplements, or drugs extend human life.

What this means for you: This review does not justify buying an “autophagy” supplement or changing your routine for longevity. It suggests that autophagy is complicated, and the best approach for people is still uncertain.