Study

PGC-1α: key regulator of mitochondrial biogenesis and function

Various

PRIMARY 2025
Summary Can boosting PGC-1α improve how cells make and use energy? Show / hide ↓

Researchers studied PGC-1α, a protein that helps control mitochondria, the parts of cells that produce energy. They examined how this protein affects mitochondrial biogenesis, meaning the creation of new mitochondria, and how well mitochondria work. This was laboratory research using cells or biological models, not a treatment trial in people. The findings suggest that PGC-1α is important for energy production, but they do not show that taking a supplement or drug to increase it improves human health.

What this means for you: You should not buy a product claiming to boost PGC-1α based on this study alone. It explains a possible biological target, but it does not prove a useful or safe treatment for people.

early evidence
DesignPRIMARY
TierTier 5, Mechanistic / animal / marketing
Year2025
JournalPMC review
Added to NO1GEVITYAug 2, 2026

Read the source

Cited by

1 encyclopedia entries reference this study.