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Layer 1 · Decision
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Pure Apigenin

NAD+ booster · Capsule · 366 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Precursor per serving
Apigenin 250 mg
Form
Capsule
List price (catalog, USD)
$55.00
Price per serving
$0.15List price divided by servings per container. A per-day cost only if the label serving is once daily.
Full label record: servings, testing, ingredients
Servings per container
366
Catalog monthly estimate
$4.51
Testing disclosure
Brand lists third-party testing; no public lab certificate listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

IngredientAmount per serving
Apigenin250 mg

What to check on the label

  • Which precursor is named. NMN and NR are different molecules and are not interchangeable milligram for milligram.
  • Whether the milligram figure is per capsule or per serving of several capsules. The catalog records per serving.
  • Whether a certificate of analysis (CoA) is published for the batch you buy. The catalog only records whether the brand lists one.
  • Added ingredients (resveratrol, TMG, quercetin) are listed with their own amounts below. Read them separately.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

5.5/10
Overall score
#43 / 52 in NAD+ booster

Tested by independent lab, top 1% value.

Read the evidence (2 studies)
Watch outEU restricted1 ingredient restricted in the EU
  • Apigenin — Food supplement, permitted (novel food status product-specific)
You can legally buy these outside the EU. Sale as a food supplement inside the EU requires a Novel Food authorisation these ingredients do not have.
Tier 5
Mechanistic / animal / marketing
Only mechanistic studies or marketing claims. No human RCT for this ingredient.
How we scored this product Show the full breakdown
Composite How this 5.5 is built. 0.50 × 3.6 + 0.20 × 7.0 + 0.10 × 10.0 + 0.10 × 5.0 + 0.05 × 7.0 + 0.05 × 8.2 = 5.5 out of 10. Safety caps applied after. 5.5
5.5 composite
Dose vs. studies50%3.6
Transparency20%7.0
Value10%10.0
Formulation10%5.0
Safety5%7.0
Community5%8.2

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Editorial verdict

Quick verdict

5.5 / 10
Best for
Full trial dose, Budget-friendly
Avoid if
No public lab certificate
Full-dose status
Meets trial dose
Price/month
$5
COA status
Not public
Biggest caveat
Dose-evidence score of 3.6 is below average for the site.
Nearest alternatives
Catalog snapshot. Check linked sources for current price, label and batch-specific testing.
Price verification
Current price: $55.00
Last price check: Sep 01, 2026
Layer 2 · Context
In plain language

Why this scored this way

This DoNotAge Pure Apigenin scores 5.5, making it below the site average. It delivers 250mg of Apigenin, inside the studied range of 25–500mg with grade D evidence (very early-stage, mostly animal models). At $0.03/day it's priced well for what you get.

What drives the score up

  • Tested by independent lab (transparency 7.0).
  • Value score of 10.0 at $0.03/day.
  • Community score of 8.2 with positive consumer feedback.

What drags it down

  • Dose-evidence score of 3.6 is below average for the site.
  • Apigenin (250.0mg is 500% of the 50mg trial dose) is well above the trial dose. More is not always better.
  • No public lab certificate available for independent verification.

Why you'd choose it

  • You want good value at $0.03/day.
  • You want a tested by independent lab product.

Why you might skip it

  • You want a product with a publicly available CoA.
  • You want a standard dose of apigenin (this product is well above it).
  • You want a higher-scoring product (this scores 5.5).
Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Apigenin

A plant flavonoid that may slow the age-related NAD+ drain by inhibiting the CD38 enzyme.

2 landmark RCTs · US: Dietary supplement, no NDI restriction · EU: Food supplement, permitted (novel food status product-specific)
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
100% of trial dose
Meets or exceeds the published effective dose
Cost at trial dose
$0.03/day at trial dose
What one effective daily dose actually costs
Transparency
7.0/10 · No public lab certificate
Independent batch testing confirmed
Consumer signals
No consumer signals collected yet
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

No public lab certificate
Certificate of Analysis not published
Without a public lab certificate, batch purity and potency cannot be independently verified.
Buyer complaints
Reddit: Some doubt about consistency of current COA transparency
Recurring themes from consumer review platforms.
Plain English

What’s inside

The main ingredients of this product, in plain language.

Apigenin250 mgEvidence D

A plant flavonoid that may slow the age-related NAD+ drain by inhibiting the CD38 enzyme.

Read about Apigenin →
Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price
$55
per bottle · 366 servings
Dose vs. research
of trial dose 100%
of published effective dose
$ / day at studied dose
$0.03
what one effective daily dose costs
$ / g active
$0.60
per gram of active substance
Independently checked

Data verification

COA status
Not public
Evidence grade
D
Per-ingredient breakdown
DApigenin

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Evidence
Apigenin
A plant flavonoid that may slow the age-related NAD+ drain by inhibiting the CD38 enzyme.
250 mg 500% of trial dose
50 mg
4.1 /5
High confidence
661 reviews across 3 platforms (3 sources)
Source diversity: 69%
RedditTrustpilotiHerb
PraiseEasier sleep onsetBetter ability to stay asleep
ComplaintsSome doubt about consistency of current COA transparency
Last checked: 2026-08-20

Consumer signals

Consumer signals gathered from 3 platforms.

Medium confidence

105 reviews · positive sentiment

PraiseEasier sleep onsetBetter ability to stay asleepIncreased deep/REM sleep tracked with wearables
Themes

DoNotAge's own product page hosts 105 reviews, overwhelmingly focused on improved sleep onset and depth, often supported by wearable-tracker data.

Compiled from a DoNotAge product page listing located during research; verified at build time.

1 thread discussed · mixed sentiment

Praise

DoNotAge grouped with ProHealth and RenueByScience as a top longevity supplier

Praise for previously published real certificates of analysis

ComplaintsSome doubt about consistency of current COA transparency
Themes

Reddit's r/Supplements community regards DoNotAge as a historically trustworthy longevity brand, with some concern about whether transparency practices have persisted.

Compiled from a Reddit r/Supplements listing located during research; verified at build time.

556 reviews · 4.1/5

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Important to know
ApigeninBioavailability is low without a fat carrier or phytosome form; grapefruit-derived apigenin retains CYP3A4 interaction risk.

Editorial notes

One of the few branded apigenin longevity products on the market; NAD+-doubling claim significantly outpaces the human evidence base for oral apigenin.

Brand owners

Spot an error?

If you are the manufacturer or brand owner of Pure Apigenin and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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