Matter is a Cognition supplement by Elysium Health. NO1GEVITY gives it a overall score of 7.1 out of 10.

How much does Matter cost?

$40.00 for 30 servings. Cost per day at the studied dose is $1.33.

Is Matter tested by independent lab?

Yes, tested by independent lab. No public lab certificate.

What is the NO1GEVITY score for Matter?

Matter scores 7.1/10 on the NO1GEVITY composite scale, based on evidence-graded dose (100% of trial dose), transparency, value, consumer signals, and formulation.

Does Matter match the dose used in clinical studies?

Matter delivers 100% of the dose used in clinical research, which is at or above the studied dose.

What is the evidence for Vitamin B6 (P-5-P)?

Vitamin B6 (P-5-P) is graded A on the NO1GEVITY evidence scale, meaning strong human evidence from multiple large RCTs (N>500) or meta-analyses confirming a longevity-relevant outcome.

What do consumers say about Matter?

Across 15 verified consumer reviews aggregated by NO1GEVITY, Matter averages 3.2 out of 5. Sources include Trustpilot, Amazon, iHerb and Labdoor where available.

Layer 1 · Decision

← All products

Elysium Health

Matter

Name: Matter
Brand: Elysium Health
SKU: elysium-matter
Price: 40.0 USD
Availability: InStock
Rating: 3.2 (15 reviews)

Cognition · Tablet · 30 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Ingredients listed: 4 ingredients listed largest listed: Omega-3 (EPA/DHA) 550 mg
Form: Tablet
List price (catalog, USD): $40.00
Price per serving: $1.33List price divided by servings per container. A per-day cost only if the label serving is once daily.

Reading notes

Multi-ingredient product. Amounts are per ingredient per serving; the product is assessed as one bundle, not as a recommendation for each ingredient.
EPA/DHA split not stored for this product. The omega-3 figure is the label's omega-3 line, not the softgel weight and not EPA+DHA.
Vitamin amounts shown in µg/mg. Labels may use IU.

Full label record: servings, testing, ingredients

Servings per container: 30
Catalog monthly estimate: $40.00
Testing disclosure: Brand lists third-party testing; no public lab certificate listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

Ingredient	Amount per serving
Vitamin B6 (P-5-P)	20 mg
Folate (5-MTHF)	1.33 mg
Vitamin B12	500 µg
Omega-3 (EPA/DHA)	550 mg

What to check on the label

The standardisation line for botanicals (for example 'bacosides 45%' or a branded extract name).
For mushroom products, whether the label states fruiting body or mycelium and the extract ratio.
Multi-ingredient formulas list each amount below. A long list usually means smaller amounts of each.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

7.1/10

Overall score

#7 / 15 in Cognition

Full trial dose, tested by independent lab.

Read the evidence (3 studies)

Add to compare Visit brand site →

Watch out

Tier 3

Ingredient RCT (matching dose)

The ingredient was tested in an RCT at the same dose this product sells.

See the 3 supporting studies

Abuknesha & Harris 2026 (Circ Arrhythm Electrophysiol) (Omega-3 (EPA/DHA))Largest meta-analysis to date (35 RCTs, 114,592 participants). Omega-3 doses below 1,500 mg/day do not increase atrial fibrillation risk. Only prescription doses above 1,500 mg/day showed 0.8% absolute risk increase. Studied at 1500 mg. This product: 550 mg.
Smith et al. 2010 (VITACOG) (Vitamin B12)271 adults 70+ with MCI, 24 months of folic acid 0.8 mg + B12 0.5 mg + B6 20 mg: whole-brain atrophy slowed from 1.08% to 0.76%/year; 53% less atrophy when homocysteine >13 umol/L. Studied at 20 mg. This product: 0 mg.
REDUCE-IT 2019 (NEJM) (Omega-3 (EPA/DHA))In 8,179 statin-treated patients with elevated triglycerides, icosapent ethyl (EPA) reduced major cardiovascular events by 25% versus placebo over a median 4.9 years.

How we scored this product Show the full breakdown

Dose vs. studies (50%) 8.0

Transparency (20%) 8.0

Value (10%) 8.2

Formulation (10%) 5.0 Default. No absorption data on file.

Safety (5%) 7.0

Community sentiment (5%) 6.8

Composite 7.1

7.1 composite

Dose vs. studies50%8.0

Transparency20%8.0

Value10%8.2

Formulation10%5.0

Safety5%7.0

Community5%6.8

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Best for

Full trial dose

Avoid if

No public lab certificate

Full-dose status

Meets trial dose

Price/month

$40

COA status

Not public

Biggest caveat

Omega-3 (EPA/DHA) (550.0mg is 28% of the 2000mg trial dose) is significantly under-dosed.

Nearest alternatives

AGZ: Nightly Sleep Support AG1 (Athletic Greens) · Score 6.2
Vital Proteins Beauty Boost Capsules Vital Proteins · Score 6.0

Catalog snapshot. Check linked sources for current price, label and batch-specific testing.

Price verification

Current price: $40.00

Last price check: Sep 01, 2026

Add to compare Visit brand site →

Layer 2 · Context

In plain language

Why this scored this way

This Elysium Health Matter scores 7.6, making it a strong scorer. It delivers 20mg of Vitamin B6 (P-5-P), inside the studied range of 10–25mg with grade A evidence (strong human trial data).

What drives the score up

Dose-evidence score of 8.0 reflects good alignment with trial doses.
Tested by independent lab (transparency 8.0).
Vitamin B6 (P-5-P) is dosed at the full research level with grade A evidence (strong human trial data).
Vitamin B12 is dosed at the full research level with grade A evidence (strong human trial data).
Vitamin B12 is also dosed at the full research level.

What drags it down

Omega-3 (EPA/DHA) (550.0mg is 28% of the 2000mg trial dose) is significantly under-dosed.
Folate (5-MTHF) (1.333mg is 333% of the 0.4mg trial dose) is well above the trial dose. More is not always better.
No public lab certificate available for independent verification.

Why you'd choose it

You want a reasonably priced cognition product.
You want Vitamin B6 (P-5-P) from a Elysium Health product.
You want a tested by independent lab product.

Why you might skip it

You want a product with a publicly available CoA.
You need a full trial dose of omega-3 (this product under-doses it).
You want a standard dose of folate (this product is well above it).

Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Vitamin B6 (P-5-P)

Active form of B6; toxicity concerns at high doses of pyridoxine.

No landmark RCTs listed · US: Dietary supplement · EU: Food supplement (limit 25 mg/day proposed)

Folate (5-MTHF)

The active form of folate; better for those with MTHFR variants.

No landmark RCTs listed · US: Dietary supplement · EU: Food supplement

Vitamin B12

Deficiency common over 50 and in vegetarians; correcting it is essential.

2 landmark RCTs · US: Dietary supplement · EU: Food supplement

Omega-3 (EPA/DHA)

The single best-supported longevity supplement most people don't take enough of.

8 landmark RCTs · US: Dietary supplement + Rx (Vascepa/Lovaza) · EU: Food supplement, health claims authorised

Full ingredient breakdown

Every active in this formula, its declared dose per serving, the dose used in the primary human trial, how much of that trial dose this product delivers, and the evidence grade for the ingredient itself.

Ingredient	Dose / serving	Research dose	% of research	Evidence grade
Vitamin B6 (P-5-P)	20 mg	20 mg	100%	A
Folate (5-MTHF)	1.333 mg	0.4 mg	333%	B
Vitamin B12	0.5 mg	1 mg	50%	A
Omega-3 (EPA/DHA)	550 mg	2000 mg	28%	A

Percentages are dose per serving ÷ primary trial dose. Below 50% means the formula is unlikely to reproduce the trial outcome for that active. Grade A = multiple large human RCTs. Grade F = no human evidence. How grades work. Full glossary →

Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research

100% of trial dose

Meets or exceeds the published effective dose

Cost at trial dose

$1.33/day at trial dose

What one effective daily dose actually costs

Transparency

8.0/10 · No public lab certificate

Independent batch testing confirmed

Consumer signals

15 reviews across platforms · 3.2/5 · medium confidence

Operational signal only, never used as clinical evidence

Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

Review advised

omega 3: bleeding risk with anticoagulants

Safety flag

omega 3: bleeding risk with anticoagulants

Dose or interaction risk detected. See ingredient page for details.

No public lab certificate

Certificate of Analysis not published

Without a public lab certificate, batch purity and potency cannot be independently verified.

Buyer complaints

Trustpilot: limited review volume on this Trustpilot listing; Reddit: skepticism about premium pricing relative to ingredient cost

Recurring themes from consumer review platforms.

Plain English

What’s inside

The main ingredients of this product, in plain language.

Vitamin B6 (P-5-P)20 mgEvidence A

Active form of B6; toxicity concerns at high doses of pyridoxine.

Read about Vitamin B6 (P-5-P) →

Folate (5-MTHF)1.333 mgEvidence B

The active form of folate; better for those with MTHFR variants.

Read about Folate (5-MTHF) →

Vitamin B120.5 mgEvidence A

Deficiency common over 50 and in vegetarians; correcting it is essential.

Read about Vitamin B12 →

Omega-3 (EPA/DHA)550 mgEvidence A

The single best-supported longevity supplement most people don't take enough of.

Read about Omega-3 (EPA/DHA) →

Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price

$40

per bottle · 30 servings

Dose vs. research

of trial dose 100%

of published effective dose

$ / day at studied dose

$1.33

what one effective daily dose costs

$ / g active

$2.33

per gram of active substance

Independently checked

Data verification

COA status

Not public

Evidence grade

ABAA

Per-ingredient breakdown

AVitamin B6 (P-5-P)

BFolate (5-MTHF)

AVitamin B12

AOmega-3 (EPA/DHA)

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient

Dose in this product

Trial dose

Evidence

Vitamin B6 (P-5-P)

Active form of B6; toxicity concerns at high doses of pyridoxine.

20 mg 100% of trial dose

20 mg

Folate (5-MTHF)

The active form of folate; better for those with MTHFR variants.

1.333 mg 333% of trial dose

0.4 mg

Vitamin B12

Deficiency common over 50 and in vegetarians; correcting it is essential.

Smith et al. 2010 (VITACOG)Clarke et al. 2014 (11 trials, 22,000)

0.5 mg 50% of trial dose

1 mg

Omega-3 (EPA/DHA)

The single best-supported longevity supplement most people don't take enough of.

REDUCE-IT 2019 (NEJM)VITAL Trial 2019 (N=25,871)Khan et al. 2021 (38 RCTs meta-analysis)

550 mg 28% of trial dose

2000 mg

3.2 /5

Medium confidence

15 reviews across 2 platforms (2 sources)

Source diversity: 46%

RedditTrustpilot

PraiseUniversity of Oxford research partnershipphysician-recommended positioning

Complaintslimited review volume on this Trustpilot listingskepticism about premium pricing relative to ingredient cost

Last checked: 2026-08-23

Consumer signals

3.2 out of 5 across 15 verified reviews on 2 platforms.

Medium confidence

Trustpilot

15 reviews · 3.2/5 · mixed sentiment

PraiseUniversity of Oxford research partnershipphysician-recommended positioning

Complaintslimited review volume on this Trustpilot listing

Themes

Elysium Health's Trustpilot listing has limited review volume, though the brand markets Matter's Oxford University research collaboration prominently.

Compiled from a Trustpilot listing located during research; verified at build time.

1 thread discussed · mixed sentiment

Praisepremium research-backed positioning

Complaintsskepticism about premium pricing relative to ingredient cost

Themes

The r/Nootropics community questions whether Elysium Matter's premium pricing is justified relative to its ingredient costs.

Compiled from a Reddit discussion thread listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

What we could not verify

We list this openly. If a claim isn't backed by a source we can trace, we'd rather flag it than repeat it.

Reddit r/Supplements community forum

mixed sentiment

Community discussion exists around supplements and brand quality, with concerns focused on third-party testing, transparency, and ingredient disclosure rather than Matter-specific experiences. No single Reddit thread is treated as a representative product review.

no direct URLchecked 2026-08-07

Important to know

Vitamin B6 (P-5-P)Don't chronically exceed 50 mg/day of pyridoxine.

Folate (5-MTHF)Folic acid (the synthetic form) can mask B12 deficiency. Choose methylfolate.

Vitamin B12Metformin depletes B12; check yearly if on it.

Omega-3 (EPA/DHA)Ethyl ester (cheaper) absorbs worse than triglyceride form unless taken with fatty meal. Check third-party oxidation testing (TOTOX <10).

Editorial notes

Matter is not the omega-3 + choline + phosphatidylserine formula sometimes assumed, it's actually a patented B6/folate/B12 tri-vitamin complex (based on Oxford's VITACOG homocysteine-lowering trial) plus a modest 250mg EPA+DHA dose and 160mg bilberry anthocyanins. Reasonable niche pick for older adults with elevated homocysteine, less compelling as a general nootropic.

Go deeper

Where this sits

Actives inside

Vitamin B6 (P-5-P)Folate (5-MTHF)Vitamin B12 Omega-3 (EPA/DHA)

Spot an error?

If you are the manufacturer or brand owner of Matter and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →

Same shelf

Other products from Elysium Health

Brand profile →

Elysium Health

Signal

NAD+ booster

Precursor per serving: NMN 250 mgCapsule · 30 servings
Price per serving: $1.33$40.00 · 30 servings
Testing: 3rd-party listed · no public lab certificate

Undisclosed amounts noted

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 7.5/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%

of trial dose

$2.67

per research-dose day, not label serving

0Trial dose2×

Catalog price · Confirm current price with www.elysiumhealth.com

Elysium Health

Vision

Antioxidant

Active per serving: Astaxanthin 6 mgSoftgel · 30 servings
Price per serving: $1.33$40.00 · 30 servings
Testing: None listed

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.8/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%

of trial dose

$1.78

per research-dose day, not label serving

0Trial dose2×

Catalog price · Confirm current price with www.elysiumhealth.com

Elysium Health

Basis

Longevity stack

Ingredients listed: 2 ingredients listedlargest listed: NR 250 mg
Price per serving: $2.00$60.00 · 30 servings
Testing: 3rd-party listed · no public lab certificate

Multi-ingredient bundle

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.8/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%

of trial dose

$2.40

per research-dose day, not label serving

0Trial dose2×

Catalog price · Confirm current price with www.elysiumhealth.com

Elysium Health

Format

Antioxidant

Ingredients listed: 3 ingredients listedlargest listed: Vitamin C 90 mg
Price per serving: $2.00$60.00 · 30 servings
Testing: 3rd-party listed · no public lab certificate

Elemental vs compound: check label

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 5.9/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

45%

of trial dose

$11.11

per research-dose day, not label serving

0Trial dose2×

Catalog price · Confirm current price with www.elysiumhealth.com

Elysium Health

Cofactor

Connective tissue

Ingredients listed: 4 ingredients listedlargest listed: Collagen Peptides 20 g
Price per serving: $2.68$75.00 · 28 servings
Testing: None listed

Multi-ingredient bundle

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 5.5/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

800%

of trial dose

$1.34

per research-dose day, not label serving

800% · over 2× trial dose0Trial dose2×

Catalog price · Confirm current price with www.elysiumhealth.com

Matter

What the label says

Reading notes

Ingredients as listed

What to check on the label

Quick verdict

Why this scored this way

What drives the score up

What drags it down

Why you'd choose it

Why you might skip it

Does the molecule work?

Full ingredient breakdown

Is this bottle good?

What's the catch?

What’s inside

Product data & verification

The numbers

Data verification

What's inside

Consumer signals

What others say (unverified)

Evidence, claims & regulation

Research behind this product

What we could not verify

Editorial notes

Where this sits

Spot an error?

Similar products

Other products from Elysium Health