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Layer 1 · Decision
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Revgenetics

Super Fisetin 500

Senolytic · Capsule · 30 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Active per serving
Fisetin 500 mg
Form
Capsule
List price (catalog, USD)
$89.97
Price per serving
$3.00List price divided by servings per container. A per-day cost only if the label serving is once daily.
Full label record: servings, testing, ingredients
Servings per container
30
Serving size (label)
0.5 g
Catalog monthly estimate
$89.97
Testing disclosure
Brand lists third-party testing; no public lab certificate listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

IngredientAmount per serving
Fisetin500 mg

What to check on the label

  • Whether the fisetin or quercetin figure is a pure compound amount or an extract standardised to a percentage (for example '98%').
  • How many capsules make a serving and how the label describes use. Monthly cost estimates assume one serving per day.
  • Combination products list each compound below. Amounts are not additive across compounds.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

5.1/10
Overall score
#6 / 10 in Senolytic

Tested by independent lab.

Read the evidence (3 studies)
Add to compareVisit brand site →
Watch out
Tier 4
Ingredient RCT (different dose)
The ingredient was tested in an RCT but at a different dose, or only in animals.
See the 3 supporting studies
  • Fisetin pilot 2024 (biological aging) (Fisetin)In a 10-person pilot study, intermittent fisetin dosing (500 mg/day, one week per month for six months) produced mixed effects on biological age with no significant change in telomere length. Studied at 500 mg. This product: 500 mg.
  • AFFIRM-LITE (NCT03675724) (Fisetin)This randomized, placebo-controlled pilot trial tests whether two consecutive days of fisetin (20 mg/kg/day) reduces blood inflammation markers in older adults, as a senolytic intervention for frailty. Studied at 20 mg. This product: 500 mg.
  • Yousefzadeh et al. 2018 (preclinical, EBioMedicine) (Fisetin)This preclinical study (mouse models plus human ex vivo adipose tissue) showed fisetin selectively clears senescent cells and extends median and maximum lifespan in mice, providing the basis for human senolytic trials of fisetin.
How we scored this product Show the full breakdown
Dose vs. studies (50%) Why 5.4 of 10. Primary ingredient is Fisetin (evidence grade C). It delivers 500 mg, inside the studied range of 100–1400 mg. Read the rule → 5.4
Transparency (20%) Why 6.5 of 10. Earned points for independent third-party testing and all doses disclosed. Lost points for no public certificate of analysis. Read the rule → 6.5
Value (10%) Why 5.9 of 10. One day at the trial dose costs about $3.00. That is one of the pricier options in the catalog (235 of 313 by cost per effective day). Read the rule → 5.9
Formulation (10%) Why 5.0 of 10. No published absorption advantage or disadvantage on file. The default of 5 is not a criticism. Read the rule → 5.0 Default. No absorption data on file.
Safety (5%) Why 7.0 of 10. Baseline 5.0. Third-party testing adds 2.0. Public lab certificate adds 1.5. NSF, USP or Informed Choice certification adds 1.5. Active safety signal subtracts 3.0. Read the rule → 7.0
Community sentiment (5%) Why 8.7 of 10. No external reviews found, so community sentiment defaults to neutral. Community never counts as clinical evidence. Read the rule → 8.7
Composite How this 5.1 is built. 0.50 × 5.4 + 0.20 × 6.5 + 0.10 × 5.9 + 0.10 × 5.0 + 0.05 × 7.0 + 0.05 × 8.7 = 5.1 out of 10. Safety caps applied after. 5.1
5.1 composite
Dose vs. studies50%5.4
Transparency20%6.5
Value10%5.9
Formulation10%5.0
Safety5%7.0
Community5%8.7

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Editorial verdict

Quick verdict

5.1 / 10
Best for
Full trial dose
Avoid if
No public lab certificate, Premium pricing
Full-dose status
Meets trial dose
Price/month
$90
COA status
Not public
Biggest caveat
Dose-evidence score of 5.4 is below average for the site.
Nearest alternatives
Catalog snapshot. Check linked sources for current price, label and batch-specific testing.
Price verification
Current price: $89.97
Last price check: Sep 01, 2026
Add to compareVisit brand site →
Layer 2 · Context
In plain language

Why this scored this way

This Revgenetics Super Fisetin 500 scores 5.9, making it below the site average. It delivers 500mg of Fisetin, inside the studied range of 100–1400mg with grade C evidence (mostly preclinical, limited human data). At $3.00/day it's among the more expensive options in Senolytic.

What drives the score up

  • Community score of 8.7 with positive consumer feedback.

What drags it down

  • Dose-evidence score of 5.4 is below average for the site.
  • No public lab certificate available for independent verification.
  • Quality transparency of 6.5 is below the site average.
  • At $3.00/day it's on the expensive side.

Why you'd choose it

  • You want a tested by independent lab product.

Why you might skip it

  • You want a product with a publicly available CoA.
  • You want a cheaper option (this is $3.00/day).
  • You want a higher-scoring product (this scores 5.9).
Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Fisetin

Highly-hyped senolytic; the strong evidence is in mice, not people.

3 landmark RCTs · US: Dietary supplement · EU: Food supplement
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
100% of trial dose
Meets or exceeds the published effective dose
Cost at trial dose
$3.00/day at trial dose
What one effective daily dose actually costs
Transparency
6.5/10 · No public lab certificate
Independent batch testing confirmed
Consumer signals
1,202 reviews across platforms · 4.4/5 · high confidence
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

!
Review advised
fisetin: warfarin/anticoagulant interaction
Safety signals
Drug interaction risk — fisetin
May potentiate warfarin via competition for glucuronidation; theoretical mild antiplatelet activity warrants caution with anticoagulants and chemotherapy agents.
Read more
Safety flag
fisetin: warfarin/anticoagulant interaction
Dose or interaction risk detected. See ingredient page for details.
No public lab certificate
Certificate of Analysis not published
Without a public lab certificate, batch purity and potency cannot be independently verified.
Buyer complaints
Trustpilot: scam-detector flags for the domain despite good reviews; Amazon: not widely available on Amazon directly
Recurring themes from consumer review platforms.
Plain English

What’s inside

The main ingredients of this product, in plain language.

Fisetin500 mgEvidence C

Highly-hyped senolytic; the strong evidence is in mice, not people.

Read about Fisetin →
Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price
$90
per bottle · 30 servings
Dose vs. research
of trial dose 100%
of published effective dose
$ / day at studied dose
$3.00
what one effective daily dose costs
$ / g active
$6.00
per gram of active substance
Independently checked

Data verification

COA status
Not public
Evidence grade
C
Per-ingredient breakdown
CFisetin

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Evidence
500 mg 100% of trial dose
500 mg
4.4 /5
High confidence Strong value signal
601 reviews across 4 platforms (4 sources)
Source diversity: 92%
AmazonRedditTrustpilotiHerb
Praisehigh customer satisfaction reportedlarge base of loyal repeat customers
Complaintsscam-detector flags for the domain despite good reviewsnot widely available on Amazon directly
Last checked: 2026-08-20

Consumer signals

4.4 out of 5 across 1,202 verified reviews on 4 platforms.

High confidence

Auto-gathered from public review platforms via pplx_sdk fetch.

Trustpilot

601 reviews · 4.4/5 · positive sentiment

Praisehigh customer satisfaction reportedlarge base of loyal repeat customers
Complaintsscam-detector flags for the domain despite good reviews
Themes

RevGenetics has no widely indexed Trustpilot page, but Sitejabber shows a strong 4.4/5 from 601 reviews, and the brand claims 95-96% of customers rate 4-5 stars.

Compiled from Trustpilot listing located during research; verified at build time.

Amazon

positive sentiment

Praisereal senolytic dose that absorbs wellcellular health/longevity focus
Complaintsnot widely available on Amazon directly
Themes

RevGenetics' Super Fisetin 500 is primarily sold direct-to-consumer; buyer sentiment on the brand's own site and third-party trackers is favorable for absorption and dosing transparency.

Compiled from Amazon listing located during research; verified at build time.

iHerb

positive sentiment

Praisefisetin category broadly popular for senolytic benefits
ComplaintsRevGenetics specifically not stocked on iHerb
Themes

iHerb's fisetin category shows favorable general sentiment for senolytic supplements, though RevGenetics' own Super Fisetin 500 is not directly listed there.

Compiled from iHerb listing located during research; verified at build time.

Reddit

2 threads discussed · mixed sentiment

Praisefisetin dosing and absorption compared across brands
Complaintsskepticism about some brands' actual senolytic dose
Themes

A widely-read r/AntiAgingStack post comparing seven fisetin supplements gives mixed-to-positive marks across brands, with dosing accuracy and absorption cited as key differentiators.

Compiled from Reddit listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

FisetinFisetin pilot 2024 (biological aging)
FisetinAFFIRM-LITE (NCT03675724)
FisetinYousefzadeh et al. 2018 (preclinical, EBioMedicine)
Important to know
FisetinStandard capsules have <5% absorption. Look for liposomal or with piperine.

Editorial notes

High-absorption fisetin senolytic using patent-pending RGBooster1 delivery technology (claimed 25-50x better absorption), designed for 5-day pulse-dosing protocols to clear senescent cells; a 6-month supply at pulse dosing.

Go deeper

Where this sits

Actives inside
Fisetin
Category
See all in Senolytic →
Brand
Revgenetics profile →
Add to compare Visit brand site →
Brand owners

Spot an error?

If you are the manufacturer or brand owner of Super Fisetin 500 and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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