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Seed Health

Seed PM-02 Sleep + Restore

Autophagy · Capsule · 30 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Ingredients listed
6 ingredients listed largest listed: Probiotics 200 mg
Form
Capsule
List price (catalog, USD)
$34.99
Price per serving
$1.17List price divided by servings per container. A per-day cost only if the label serving is once daily.

Reading notes

  • Catalog notes mention undisclosed or blended amounts; the figures shown are only what the label states.
  • Multi-ingredient product. Amounts are per ingredient per serving; the product is assessed as one bundle, not as a recommendation for each ingredient.
  • CFU count and strain list are not stored in the catalog; see the product notes and label.
  • Vitamin amounts shown in µg/mg. Labels may use IU.
Full label record: servings, testing, ingredients
Servings per container
30
Catalog monthly estimate
$34.99
Testing disclosure
Brand lists third-party testing; no public lab certificate listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

IngredientAmount per serving
Riboflavin (B2)1.3 mg
Melatonin500 µg
PQQ151 mg
Pterostilbene12 mg
Probiotics200 mg
Quercetin33 mg

What to check on the label

  • Read the spermidine line, not the extract line. '800 mg wheat-germ extract' may contain only a few milligrams of spermidine.
  • Check the serving size. Capsule counts per serving vary from one to three.
  • If wheat-germ based, the label states gluten content. The catalog does not store allergen data.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

4.5/10
Overall score
#23 / 25 in Autophagy

Tested by independent lab.

Read the evidence (3 studies)
Add to compareVisit brand site →
Watch outEU restricted1 ingredient restricted in the EU
  • Probiotics — Food supplement (some strains Novel Food)
You can legally buy these outside the EU. Sale as a food supplement inside the EU requires a Novel Food authorisation these ingredients do not have.
Tier 4
Ingredient RCT (different dose)
The ingredient was tested in an RCT but at a different dose, or only in animals.
See the 3 supporting studies
  • Nakano et al. 2012 (PQQ)8 weeks of 20 mg/day improved fatigue and quality-of-life scores in adults. Studied at 20 mg. This product: 151 mg.
  • HoA 2024 (BVL/NVWA, EU) (Melatonin)26-country EU working group prioritized melatonin for Article 8 restriction. French and Norwegian risk assessments raised concerns about headaches, dizziness, drowsiness, and cardiovascular, neurological, digestive and psychological symptoms.
  • Ferracioli-Oda 2013 (PLOS ONE) (Melatonin)Meta-analysis: melatonin reduces sleep onset latency and improves total sleep time.
How we scored this product Show the full breakdown
Dose vs. studies (50%) Why 5.5 of 10. Primary ingredient is Riboflavin (B2) (evidence grade B). It delivers only 1 mg, 1% of the studied range low edge (100 mg). Too low to expect the trial effect. Read the rule → 5.5
Transparency (20%) Why 6.0 of 10. Earned points for independent third-party testing and all doses disclosed. Lost points for no public certificate of analysis. Read the rule → 6.0
Value (10%) Why 3.0 of 10. One day at the trial dose costs about $358.87. That is one of the pricier options in the catalog (312 of 313 by cost per effective day). Read the rule → 3.0
Formulation (10%) Why 5.0 of 10. No published absorption advantage or disadvantage on file. The default of 5 is not a criticism. Read the rule → 5.0 Default. No absorption data on file.
Safety (5%) Why 7.0 of 10. Baseline 5.0. Third-party testing adds 2.0. Public lab certificate adds 1.5. NSF, USP or Informed Choice certification adds 1.5. Active safety signal subtracts 3.0. Read the rule → 7.0
Community sentiment (5%) Why 3.8 of 10. No external reviews found, so community sentiment defaults to neutral. Community never counts as clinical evidence. Read the rule → 3.8
Composite How this 4.5 is built. 0.50 × 5.5 + 0.20 × 6.0 + 0.10 × 3.0 + 0.10 × 5.0 + 0.05 × 7.0 + 0.05 × 3.8 = 4.5 out of 10. Safety caps applied after. 4.5
4.5 composite
Dose vs. studies50%5.5
Transparency20%6.0
Value10%3.0
Formulation10%5.0
Safety5%7.0
Community5%3.8

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Editorial verdict

Quick verdict

4.5 / 10
Best for
Basic coverage
Avoid if
Only 1% of trial dose, No public lab certificate
Full-dose status
1% of trial dose
Price/month
$35
COA status
Not public
Biggest caveat
Dose-evidence score of 5.5 is below average for the site.
Nearest alternatives
Catalog snapshot. Check linked sources for current price, label and batch-specific testing.
Price verification
Current price: $34.99
Last price check: Sep 01, 2026
Add to compareVisit brand site →
Layer 2 · Context
In plain language

Why this scored this way

This Seed Health Seed PM-02 Sleep + Restore scores 5.3, making it among the lowest-scoring products we track. It delivers 0mg of Melatonin, inside the studied range of 0–2mg with grade A evidence (strong human trial data). At $358.87/day it's among the more expensive options in Autophagy.

What drives the score up

  • Melatonin is dosed at the full research level with grade A evidence (strong human trial data).

What drags it down

  • Dose-evidence score of 5.5 is below average for the site.
  • Overall dose is only 1% of the trial dose across ingredients.
  • Riboflavin (B2) (1.3mg is 0% of the 400mg trial dose) is significantly under-dosed.
  • Pterostilbene (12.0mg is 12% of the 100mg trial dose) is significantly under-dosed.
  • Quercetin (33.0mg is 7% of the 500mg trial dose) is significantly under-dosed.

Why you'd choose it

  • You want Melatonin from a Seed Health product.
  • You want a tested by independent lab product.

Why you might skip it

  • You want a product with a publicly available CoA.
  • You need a full trial dose of riboflavin (this product under-doses it).
  • You want a standard dose of pqq (this product is well above it).
Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Riboflavin (B2)

Cheap B-vitamin; migraine prevention at 400 mg/day.

1 landmark RCT · US: Dietary supplement · EU: Food supplement
Melatonin

The circadian rhythm hormone; low doses (0.3 to 1 mg) work best.

2 landmark RCTs · US: Dietary supplement · EU: Prescription drug ≥2 mg; food supplement 0.5 to 1.9 mg
PQQ

Promising cofactor for mitochondrial biogenesis; human evidence remains thin.

1 landmark RCT · US: Dietary supplement · EU: Novel Food authorised
Pterostilbene

Resveratrol's more bioavailable cousin, mostly used in blends.

1 landmark RCT · US: Dietary supplement · EU: Food supplement
Probiotics

Strain-specific benefits; forget 'total CFU' marketing.

No landmark RCTs listed · US: Dietary supplement · EU: Food supplement (some strains Novel Food)
Quercetin

Best-studied 'senolytic' ingredient, though evidence is early.

4 landmark RCTs · US: Dietary supplement · EU: Food supplement (extract-dependent)

Full ingredient breakdown

Every active in this formula, its declared dose per serving, the dose used in the primary human trial, how much of that trial dose this product delivers, and the evidence grade for the ingredient itself.

IngredientDose / servingResearch dose% of researchEvidence grade
Riboflavin (B2)1.3 mg400 mg0%B
Melatonin0.5 mg0.5 mg100%A
PQQ151 mg20 mg755%C
Pterostilbene12 mg100 mg12%D
Probiotics200 mgnot establishedn/aB
Quercetin33 mg500 mg7%B

Percentages are dose per serving ÷ primary trial dose. Below 50% means the formula is unlikely to reproduce the trial outcome for that active. Grade A = multiple large human RCTs. Grade F = no human evidence. How grades work. Full glossary →

Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
1% of trial dose
Well below the trial dose
Cost at trial dose
$358.87/day at trial dose
What one effective daily dose actually costs
Transparency
6.0/10 · No public lab certificate
Independent batch testing confirmed
Consumer signals
No consumer signals collected yet
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

!
Review advised
melatonin: warfarin/anticoagulant interaction
Safety signals
Drug interaction risk — melatonin
Metabolized by CYP1A2 — caution with potent CYP1A2 inhibitors (e.g., fluvoxamine). Increases sedation when combined with benzodiazepines, zolpidem, or eszopiclone. May increase prothrombin time/INR with warfarin (case reports of increased bleeding). Can reduce effectiveness of extended-release nifedipine and immunosuppressants used after organ transplant.
Read more
Safety flag
melatonin: warfarin/anticoagulant interaction
Dose or interaction risk detected. See ingredient page for details.
No public lab certificate
Certificate of Analysis not published
Without a public lab certificate, batch purity and potency cannot be independently verified.
Underdosed
Dose at 1% of trial dose
Below 50% of the dose used in published clinical trials.
Buyer complaints
Trustpilot: customer service unresponsiveness; Trustpilot: difficulty contacting company
Recurring themes from consumer review platforms.
Plain English

What’s inside

The main ingredients of this product, in plain language.

Riboflavin (B2)1.3 mgEvidence B

Cheap B-vitamin; migraine prevention at 400 mg/day.

Read about Riboflavin (B2) →
Melatonin0.5 mgEvidence A

The circadian rhythm hormone; low doses (0.3 to 1 mg) work best.

Read about Melatonin →
PQQ151 mgEvidence C

Promising cofactor for mitochondrial biogenesis; human evidence remains thin.

Read about PQQ →
Pterostilbene12 mgEvidence D

Resveratrol's more bioavailable cousin, mostly used in blends.

Read about Pterostilbene →
Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price
$35
per bottle · 30 servings
Dose vs. research
Below trial dose 1%
of published effective dose
$ / day at studied dose
$358.87
what one effective daily dose costs
$ / g active
$2.93
per gram of active substance
Independently checked

Data verification

COA status
Not public
Evidence grade
BACDBB
Per-ingredient breakdown
BRiboflavin (B2)
AMelatonin
CPQQ
DPterostilbene
BProbiotics
BQuercetin

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Evidence
Riboflavin (B2)
Cheap B-vitamin; migraine prevention at 400 mg/day.
Schoenen 1998
1.3 mg 0% of trial dose
400 mg
Melatonin
The circadian rhythm hormone; low doses (0.3 to 1 mg) work best.
HoA 2024 (BVL/NVWA, EU)Ferracioli-Oda 2013 (PLOS ONE)
0.5 mg 100% of trial dose
0.5 mg
PQQ
Promising cofactor for mitochondrial biogenesis; human evidence remains thin.
Nakano et al. 2012
151 mg 755% of trial dose
20 mg
Pterostilbene
Resveratrol's more bioavailable cousin, mostly used in blends.
Riche et al. 2013
12 mg 12% of trial dose
100 mg
Probiotics
Strain-specific benefits; forget 'total CFU' marketing.
200 mg
n/a mg
33 mg 7% of trial dose
500 mg
1.6 /5
Low confidence Price exceeds satisfaction
116 reviews across 1 platforms (1 sources)
Source diversity: 23%
Trustpilot
Praisebiphasic melatonin dosing praised in independent reviews
Complaintscustomer service unresponsivenessdifficulty contacting company
Last checked: 2026-08-20

Consumer signals

Consumer signals gathered from 1 platform.

Compiled from a Trustpilot listing located during research; verified at build time.

Medium confidence
Trustpilot

116 reviews · 1.6/5 · negative sentiment

Praisebiphasic melatonin dosing praised in independent reviews
Complaintscustomer service unresponsivenessdifficulty contacting companybilling/subscription issues
Themes

Seed's overall Trustpilot rating is notably low at 1.6/5 across 116 reviews, with most complaints about customer service responsiveness rather than the PM-02 product formulation itself.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Riboflavin (B2)Schoenen 1998
MelatoninHoA 2024 (BVL/NVWA, EU)
MelatoninFerracioli-Oda 2013 (PLOS ONE)
PQQNakano et al. 2012
PterostilbeneRiche et al. 2013
QuercetinHickson et al. 2019 (senolytics in humans)
QuercetinQuercetin + blood pressure 2016 meta-analysis
QuercetinQuercetin + blood pressure 2022 meta-analysis
QuercetinD+Q pilot trial 2025 (F1000Research)
Important to know
Riboflavin (B2)Turns urine bright yellow (harmless).
MelatoninRx in EU, OTC in US. US dietary-supplement melatonin is often mislabeled by 3 to 4× the stated dose (2017 audit).
PQQPQQ is very expensive to synthesise, so cheap products may under-deliver. Look for third-party COA.
PterostilbeneHigh-dose pterostilbene can raise LDL. Keep to <150 mg/day unless working with a clinician.
ProbioticsRefrigerated ≠ better if the strain is shelf-stable. Look for CFU at expiry, not at manufacture.
QuercetinPlain quercetin dihydrate has poor absorption. Phytosome forms deliver 10 to 20× more into blood.

Editorial notes

A melatonin sleep aid (500mcg, EU-legal dose range) layered with a genuinely longevity-relevant but under-dosed 'Cellular Renewal Complex' (pterostilbene + spermidine, 12mg combined) and undisclosed-dose PQQ and Shoden ashwagandha, the longevity angle here is real but the doses are too small/opaque to expect research-level autophagy or sirtuin effects.

Go deeper

Where this sits

Actives inside
Riboflavin (B2)MelatoninPQQPterostilbeneProbioticsQuercetin
Category
See all in Autophagy →
Brand
Seed Health profile →
Add to compare Visit brand site →
Brand owners

Spot an error?

If you are the manufacturer or brand owner of Seed PM-02 Sleep + Restore and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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