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Layer 1 · Decision
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Berberine 500mg with Ceylon Cinnamon

Metabolic · Capsule · 30 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Ingredients listed
3 ingredients listed largest listed: Berberine 500 mg
Form
Capsule
List price (catalog, USD)
$54.87
Price per serving
$1.83List price divided by servings per container. A per-day cost only if the label serving is once daily.

Reading notes

  • Multi-ingredient product. Amounts are per ingredient per serving; the product is assessed as one bundle, not as a recommendation for each ingredient.
Full label record: servings, testing, ingredients
Servings per container
30
Serving size (label)
1 g
Catalog monthly estimate
$54.87
Testing disclosure
Brand lists third-party testing; no public lab certificate listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

IngredientAmount per serving
Berberine500 mg
Alpha-Lipoic Acid60 mg
Piperine5 mg

What to check on the label

  • Whether the figure is per capsule or per day, and how many capsules the label's daily serving contains.
  • The salt form named (berberine HCl, dihydroberberine, Ca-AKG). The catalog does not convert between forms.
  • Many labels carry interaction warnings for berberine. Read the label warning and the safety section on this page.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

4.6/10
Overall score
#19 / 20 in Metabolic

Tested by independent lab.

Read the evidence (3 studies)
Watch out
Tier 4
Ingredient RCT (different dose)
The ingredient was tested in an RCT but at a different dose, or only in animals.
See the 3 supporting studies
How we scored this product Show the full breakdown
Composite How this 4.6 is built. 0.50 × 6.5 + 0.20 × 3.0 + 0.10 × 3.0 + 0.10 × 5.0 + 0.05 × 7.0 + 0.05 × 8.8 = 4.6 out of 10. Safety caps applied after. 4.6
4.6 composite
Dose vs. studies50%6.5
Transparency20%3.0
Value10%3.0
Formulation10%5.0
Safety5%7.0
Community5%8.8

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Editorial verdict

Quick verdict

4.6 / 10
Best for
Basic coverage
Avoid if
Only 56% of trial dose, No public lab certificate
Full-dose status
56% of trial dose
Price/month
$55
COA status
Not public
Biggest caveat
Berberine (500mg is 33% of the 1500mg trial dose) is significantly under-dosed.
Nearest alternatives
Catalog snapshot. Check linked sources for current price, label and batch-specific testing.
Price verification
Current price: $54.87
Last price check: Sep 01, 2026
Layer 2 · Context
In plain language

Why this scored this way

This ViViYouth Berberine 500mg with Ceylon Cinnamon scores 5.4, making it among the lowest-scoring products we track. It delivers 500mg of Berberine, 55% of the studied range low edge (900mg) with grade A evidence (strong human trial data). At $5.49/day it's among the more expensive options in Metabolic.

What drives the score up

  • Dose-evidence score of 6.5 shows decent alignment with trial doses.
  • Community score of 8.8 with positive consumer feedback.
  • Berberine has grade A evidence and is dosed at 55% of the trial dose.

What drags it down

  • Berberine (500mg is 33% of the 1500mg trial dose) is significantly under-dosed.
  • Alpha-Lipoic Acid (60mg is 10% of the 600mg trial dose) is significantly under-dosed.
  • Piperine (5mg is 25% of the 20mg trial dose) is significantly under-dosed.
  • No public lab certificate available for independent verification.
  • Quality transparency of 3.0 is below the site average.

Why you'd choose it

  • You want Berberine from a ViViYouth product.
  • You want a tested by independent lab product.

Why you might skip it

  • You want a product with a publicly available CoA.
  • You need a full trial dose of berberine (this product under-doses it).
  • You want a cheaper option (this is $5.49/day).
Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Berberine

Plant-derived AMPK activator; near-drug-strength effects on blood sugar and lipids.

1 landmark RCT · US: Dietary supplement · EU: Restricted in Italy (drug status ≥10 mg); food supplement elsewhere
Alpha-Lipoic Acid

Mitochondrial cofactor with genuine efficacy in diabetic neuropathy.

4 landmark RCTs · US: Dietary supplement · EU: Restricted in Italy/EU (safety review); food supplement elsewhere
Piperine

The pungent alkaloid in black pepper, famous for dramatically increasing the bioavailability of curcumin and other poorly absorbed compounds when co-administered.

2 landmark RCTs · US: GRAS as a spice/flavoring; also sold as a dietary supplement ingredient under DSHEA. · EU: Sold as a food supplement ingredient/spice extract; permitted as a food additive/flavoring as well.

Full ingredient breakdown

Every active in this formula, its declared dose per serving, the dose used in the primary human trial, how much of that trial dose this product delivers, and the evidence grade for the ingredient itself.

IngredientDose / servingResearch dose% of researchEvidence grade
Berberine500 mg1500 mg33%A
Alpha-Lipoic Acid60 mg600 mg10%A
Piperine5 mg20 mg25%B

Percentages are dose per serving ÷ primary trial dose. Below 50% means the formula is unlikely to reproduce the trial outcome for that active. Grade A = multiple large human RCTs. Grade F = no human evidence. How grades work. Full glossary →

Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
56% of trial dose
Below the full trial dose
Cost at trial dose
$5.49/day at trial dose
What one effective daily dose actually costs
Transparency
3.0/10 · No public lab certificate
Independent batch testing confirmed
Consumer signals
13,833 reviews across platforms · 4.4/5 · medium confidence
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

Safety signals
Drug interaction risk — berberine
Berberine inhibits CYP3A4, CYP2D6, and CYP2C9 even at moderate doses. Documented interactions with immunosuppressants, statins, anticoagulants, and antidiabetic drugs. Consult a physician if taking prescription medications.
Read more
Safety flag
berberine: CYP3A4 interactions
Dose or interaction risk detected. See ingredient page for details.
No public lab certificate
Certificate of Analysis not published
Without a public lab certificate, batch purity and potency cannot be independently verified.
Low transparency
3.0/10 quality transparency
Limited public information about sourcing, testing, or manufacturing.
Plain English

What’s inside

The main ingredients of this product, in plain language.

Berberine500 mgEvidence A

Plant-derived AMPK activator; near-drug-strength effects on blood sugar and lipids.

Read about Berberine →
Alpha-Lipoic Acid60 mgEvidence A

Mitochondrial cofactor with genuine efficacy in diabetic neuropathy.

Read about Alpha-Lipoic Acid →
Piperine5 mgEvidence B

The pungent alkaloid in black pepper, famous for dramatically increasing the bioavailability of curcumin and other poorly absorbed compounds when co-administered.

Read about Piperine →
Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price
$55
per bottle · 30 servings
Dose vs. research
Below trial dose 56%
of published effective dose
$ / day at studied dose
$5.49
what one effective daily dose costs
$ / g active
$3.24
per gram of active substance
Independently checked

Data verification

COA status
Not public
Evidence grade
AAB
Per-ingredient breakdown
ABerberine
AAlpha-Lipoic Acid
BPiperine

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Evidence
Berberine
Plant-derived AMPK activator; near-drug-strength effects on blood sugar and lipids.
500 mg 33% of trial dose
1500 mg
60 mg 10% of trial dose
600 mg
Piperine
The pungent alkaloid in black pepper, famous for dramatically increasing the bioavailability of curcumin and other poorly absorbed compounds when co-administered.
5 mg 25% of trial dose
20 mg
4.4 /5
Medium confidence Strong value signal
13,833 reviews across 2 platforms (2 sources)
Source diversity: 46%
Brand siteReview aggregator
Last checked: 2026-08-20

Consumer signals

4.4 out of 5 across 13,833 verified reviews on 2 platforms.

Medium confidence

Auto-gathered from public review platforms via pplx_sdk fetch.

13,833 reviews · 4.4/5 · positive sentiment

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Important to know
BerberineStandard berberine has ~5% oral bioavailability. Dihydroberberine and berberine phytosomes absorb better. Split doses across meals (500 mg × 3) to avoid GI upset.
Alpha-Lipoic AcidCheap 'ALA' products sell the racemic form (50% inactive). Look for 'R-ALA' or 'R-alpha-lipoic acid'. Take on empty stomach.
PiperineBy design, increases absorption/blood levels of many co-administered drugs and supplements, which can raise the risk of interactions or unexpectedly elevated drug levels (e.g., with certain prescription medications); can cause GI irritation at higher doses in sensitive individuals.

Editorial notes

5-ingredient berberine capsule. 500 mg berberine HCl, 100 mg Ceylon cinnamon extract (10:1), 60 mg alpha-lipoic acid, 50 mcg chromium (from chromium picolinate), and 5 mg BioPerine black pepper extract (95% piperine) per 2-capsule serving. 60 capsules per bottle, 30 servings. GMP-certified, tested by independent lab for purity and potency, non-GMO, gluten-free. No public certificate of analysis.

Brand owners

Spot an error?

If you are the manufacturer or brand owner of Berberine 500mg with Ceylon Cinnamon and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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