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Layer 1 · Decision
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Avea Life

Collagen Activator

Connective tissue · Powder · 30 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Ingredients listed
4 ingredients listed largest listed: Glycine 5 g
Form
Powder
List price (catalog, USD)
$92.00
Price per serving
$3.07List price divided by servings per container. A per-day cost only if the label serving is once daily.

Reading notes

  • Multi-ingredient product. Amounts are per ingredient per serving; the product is assessed as one bundle, not as a recommendation for each ingredient.
  • Vitamin amounts shown in µg/mg. Labels may use IU.
Full label record: servings, testing, ingredients
Servings per container
30
Serving size (label)
11 g
Catalog monthly estimate
$92.00
Testing disclosure
No third-party testing listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

IngredientAmount per serving
Glycine5 g
Ca-AKG1,000 mg
Astaxanthin4 mg
Vitamin C48 mg

What to check on the label

  • Grams of collagen per scoop and how many scoops the label calls a serving. Flavoured powders carry more filler per gram.
  • The collagen source and type stated on the label. The catalog does not infer them.
  • Any added actives (hyaluronic acid, vitamin C, biotin) with their own amounts, listed below.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

6.5/10
Overall score
#9 / 19 in Connective tissue

See the score breakdown below.

Read the evidence (3 studies)
Add to compareVisit brand site →
Watch out
Tier 3
Ingredient RCT (matching dose)
The ingredient was tested in an RCT at the same dose this product sells.
See the 3 supporting studies
How we scored this product Show the full breakdown
Dose vs. studies (50%) Why 6.2 of 10. Primary ingredient is Glycine (evidence grade B). It delivers 5000 mg, inside the studied range of 1000–10000 mg. Read the rule → 6.2
Transparency (20%) Why 7.0 of 10. Earned points for all doses disclosed. Lost points for no public certificate of analysis and no independent third-party testing. Read the rule → 7.0
Value (10%) Why 7.5 of 10. One day at the trial dose costs about $1.84. That is more expensive than average (186 of 313 by cost per effective day). Read the rule → 7.5
Formulation (10%) Why 5.0 of 10. No published absorption advantage or disadvantage on file. The default of 5 is not a criticism. Read the rule → 5.0 Default. No absorption data on file.
Safety (5%) Why 5.0 of 10. Baseline 5.0. Third-party testing adds 2.0. Public lab certificate adds 1.5. NSF, USP or Informed Choice certification adds 1.5. Active safety signal subtracts 3.0. Read the rule → 5.0
Community sentiment (5%) Why 9.3 of 10. No external reviews found, so community sentiment defaults to neutral. Community never counts as clinical evidence. Read the rule → 9.3
Composite How this 6.5 is built. 0.50 × 6.2 + 0.20 × 7.0 + 0.10 × 7.5 + 0.10 × 5.0 + 0.05 × 5.0 + 0.05 × 9.3 = 6.5 out of 10. Safety caps applied after. 6.5
6.5 composite
Dose vs. studies50%6.2
Transparency20%7.0
Value10%7.5
Formulation10%5.0
Safety5%5.0
Community5%9.3

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Editorial verdict

Quick verdict

6.5 / 10
Best for
Full trial dose
Avoid if
No public lab certificate, Premium pricing
Full-dose status
Meets trial dose
Price/month
$92
COA status
Not public
Biggest caveat
Vitamin C (48mg is 10% of the 500mg trial dose) is significantly under-dosed.
Nearest alternatives
Catalog snapshot. Check linked sources for current price, label and batch-specific testing.
Price verification
Current price: $92.00
Last price check: Sep 01, 2026
Add to compareVisit brand site →
Layer 2 · Context
In plain language

Why this scored this way

This Avea Life Collagen Activator scores 6.5, making it a mid-tier product with both strengths and weaknesses. It delivers 48mg of Vitamin C, 24% of the studied range low edge (200mg) with grade A evidence (strong human trial data). The quality transparency (7.0) is limited by the lack of third-party testing. At $1.84/day it's among the more expensive options in Connective tissue.

What drives the score up

  • Dose-evidence score of 6.2 shows decent alignment with trial doses.
  • Community score of 9.3 with positive consumer feedback.
  • Glycine is dosed at the full research level with grade B evidence (promising human data, not yet comprehensive).
  • Glycine is also dosed at the full research level.

What drags it down

  • Vitamin C (48mg is 10% of the 500mg trial dose) is significantly under-dosed.
  • Glycine (5000mg is 167% of the 3000mg trial dose) is well above the trial dose. More is not always better.
  • No third-party testing, which caps the quality transparency.
  • At $1.84/day it's on the expensive side.

Why you'd choose it

  • You want Vitamin C from a Avea Life product.

Why you might skip it

  • You want third-party verified purity.
  • You want a product with a publicly available CoA.
  • You need a full trial dose of vitamin c (this product under-doses it).
Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Glycine

Cheap amino acid with better sleep and glutathione-precursor benefits.

1 landmark RCT · US: Dietary supplement / GRAS · EU: Food supplement
Ca-AKG

Krebs-cycle intermediate sold as a longevity supplement. Lifespan results exist in mice; human evidence is a single retrospective, company-funded analysis.

2 landmark RCTs · US: Dietary ingredient · EU: Permitted as food supplement
Astaxanthin

The 'sunscreen from within' with real skin, eye, and endurance data.

1 landmark RCT · US: Dietary supplement · EU: Food supplement (max 8 mg/day per EFSA)
Vitamin C

Correcting deficiency is important; megadoses rarely add benefit.

4 landmark RCTs · US: Dietary supplement · EU: Food supplement

Full ingredient breakdown

Every active in this formula, its declared dose per serving, the dose used in the primary human trial, how much of that trial dose this product delivers, and the evidence grade for the ingredient itself.

IngredientDose / servingResearch dose% of researchEvidence grade
Glycine5000 mg3000 mg167%B
Ca-AKG1000 mg1000 mg100%D
Astaxanthin4 mg8 mg50%B
Vitamin C48 mg500 mg10%A

Percentages are dose per serving ÷ primary trial dose. Below 50% means the formula is unlikely to reproduce the trial outcome for that active. Grade A = multiple large human RCTs. Grade F = no human evidence. How grades work. Full glossary →

Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
100% of trial dose
Meets or exceeds the published effective dose
Cost at trial dose
$1.84/day at trial dose
What one effective daily dose actually costs
Transparency
7.0/10 · No public lab certificate
No third-party testing disclosed
Consumer signals
700 reviews across platforms · 4.7/5 · medium confidence
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

Safety signals
Drug interaction risk — glycine
May reduce the efficacy of clozapine.
Read more
No public lab certificate
Certificate of Analysis not published
Without a public lab certificate, batch purity and potency cannot be independently verified.
No third-party testing
Independent lab verification not disclosed
The brand does not publish evidence of independent batch testing.
Plain English

What’s inside

The main ingredients of this product, in plain language.

Glycine5000 mgEvidence B

Cheap amino acid with better sleep and glutathione-precursor benefits.

Read about Glycine →
Ca-AKG1000 mgEvidence D

Krebs-cycle intermediate sold as a longevity supplement. Lifespan results exist in mice; human evidence is a single retrospective, company-funded analysis.

Read about Ca-AKG →
Astaxanthin4 mgEvidence B

The 'sunscreen from within' with real skin, eye, and endurance data.

Read about Astaxanthin →
Vitamin C48 mgEvidence A

Correcting deficiency is important; megadoses rarely add benefit.

Read about Vitamin C →
Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price
$92
per bottle · 30 servings
Dose vs. research
of trial dose 100%
of published effective dose
$ / day at studied dose
$1.84
what one effective daily dose costs
$ / g active
$0.51
per gram of active substance
Independently checked

Data verification

COA status
Not public
Evidence grade
BDBA
Per-ingredient breakdown
BGlycine
DCa-AKG
BAstaxanthin
AVitamin C

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Evidence
Glycine
Cheap amino acid with better sleep and glutathione-precursor benefits.
Kumar et al. 2021 (Clin Transl Med)
5000 mg 167% of trial dose
3000 mg
Ca-AKG
Krebs-cycle intermediate sold as a longevity supplement. Lifespan results exist in mice; human evidence is a single retrospective, company-funded analysis.
Asadi Shahmirzadi et al. 2020 (Cell Metabolism)Demidenko et al. 2021 (Aging, ABLE analysis)
1000 mg 100% of trial dose
1000 mg
Astaxanthin
The 'sunscreen from within' with real skin, eye, and endurance data.
Tominaga et al. 2012
4 mg 50% of trial dose
8 mg
48 mg 10% of trial dose
500 mg
4.7 /5
Medium confidence Strong value signal
700 reviews across 2 platforms (2 sources)
Source diversity: 46%
Review aggregatorTrustpilot
Last checked: 2026-08-20

Consumer signals

4.7 out of 5 across 700 verified reviews on 2 platforms.

Medium confidence

Auto-gathered from public review platforms via pplx_sdk fetch.

Trustpilot

Review aggregator

700 reviews · 4.7/5 · positive sentiment

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

GlycineKumar et al. 2021 (Clin Transl Med)
Ca-AKGAsadi Shahmirzadi et al. 2020 (Cell Metabolism)
Ca-AKGDemidenko et al. 2021 (Aging, ABLE analysis)
AstaxanthinTominaga et al. 2012
Vitamin CVitamin C umbrella review 2022 (76 meta-analyses)
Vitamin CVitamin C + telomere length 2023 (NHANES)
Vitamin CVitamin C and CVD 2020 (Antioxidants)
Vitamin CCochrane: Vitamin C for common cold
Important to know
GlycineNone major. Very sweet in powder form, mix in water or coffee.
Ca-AKGLong-term human safety data is essentially absent. Biological-age tests used in marketing are proxies, not proof of slowed aging.
AstaxanthinSynthetic astaxanthin (from petrochemicals) is not the same stereoisomer as natural. Insist on Haematococcus source.
Vitamin CHigh doses cause GI upset. Buffered forms gentler. Liposomal marketing typically overstated for chronic use.

Editorial notes

Sachet powder. Contains patented Colgevity blend (8400 mg): 5000 mg L-glycine, 1700 mg L-proline, 1700 mg L-hydroxyproline in 3:1:1 ratio. Plus 1000 mg calcium-AKG, 4 mg astaxanthin, 48 mg vitamin C from acerola. Underlying research (npj Aging 2025, n=25 observational trial) reported 1.4-year biological age reduction at 6 months.

Go deeper

Where this sits

Actives inside
GlycineCa-AKGAstaxanthinVitamin C
Category
See all in Connective tissue →
Brand
Avea Life profile →
Add to compare Visit brand site →
Brand owners

Spot an error?

If you are the manufacturer or brand owner of Collagen Activator and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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