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Layer 1 · Decision
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Berberine HCl Powder

Metabolic · Powder · 100 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Active per serving
Berberine 500 mg
Form
Powder
List price (catalog, USD)
$23.97
Price per serving
$0.24List price divided by servings per container. A per-day cost only if the label serving is once daily.
Full label record: servings, testing, ingredients
Servings per container
100
Catalog monthly estimate
$7.19
Testing disclosure
No third-party testing listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

IngredientAmount per serving
Berberine500 mg

What to check on the label

  • Whether the figure is per capsule or per day, and how many capsules the label's daily serving contains.
  • The salt form named (berberine HCl, dihydroberberine, Ca-AKG). The catalog does not convert between forms.
  • Many labels carry interaction warnings for berberine. Read the label warning and the safety section on this page.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

6.0/10
Overall score
#8 / 20 in Metabolic

Top 11% value.

Read the evidence (1 study)
Watch out
Tier 4
Ingredient RCT (different dose)
The ingredient was tested in an RCT but at a different dose, or only in animals.
See the 1 supporting study
How we scored this product Show the full breakdown
Composite How this 6.0 is built. 0.50 × 7.2 + 0.20 × 6.0 + 0.10 × 9.1 + 0.10 × 5.0 + 0.05 × 5.0 + 0.05 × 6.6 = 6.0 out of 10. Safety caps applied after. 6.0
6.0 composite
Dose vs. studies50%7.2
Transparency20%6.0
Value10%9.1
Formulation10%5.0
Safety5%5.0
Community5%6.6

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Editorial verdict

Quick verdict

6.0 / 10
Best for
Budget-friendly
Avoid if
Only 56% of trial dose, No public lab certificate
Full-dose status
56% of trial dose
Price/month
$7
COA status
Not public
Biggest caveat
Berberine (500.0mg is 33% of the 1500mg trial dose) is significantly under-dosed.
Nearest alternatives
Catalog snapshot. Check linked sources for current price, label and batch-specific testing.
Price verification
Current price: $23.97
Last price check: Sep 01, 2026
Layer 2 · Context
In plain language

Why this scored this way

This BulkSupplements Berberine HCl Powder scores 6.8, making it a mid-tier product with both strengths and weaknesses. It delivers 500mg of Berberine, 55% of the studied range low edge (900mg) with grade A evidence (strong human trial data). The quality transparency (6.0) is limited by the lack of third-party testing.

What drives the score up

  • Dose-evidence score of 7.2 shows decent alignment with trial doses.
  • Berberine has grade A evidence and is dosed at 55% of the trial dose.

What drags it down

  • Berberine (500.0mg is 33% of the 1500mg trial dose) is significantly under-dosed.
  • No third-party testing, which caps the quality transparency.
  • Quality transparency of 6.0 is below the site average.

Why you'd choose it

  • You want good value at $0.72/day.
  • You want Berberine from a BulkSupplements product.
  • You want doses that align with published research.

Why you might skip it

  • You want third-party verified purity.
  • You want a product with a publicly available CoA.
  • You need a full trial dose of berberine (this product under-doses it).
Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Berberine

Plant-derived AMPK activator; near-drug-strength effects on blood sugar and lipids.

1 landmark RCT · US: Dietary supplement · EU: Restricted in Italy (drug status ≥10 mg); food supplement elsewhere
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
56% of trial dose
Below the full trial dose
Cost at trial dose
$0.72/day at trial dose
What one effective daily dose actually costs
Transparency
6.0/10 · No public lab certificate
No third-party testing disclosed
Consumer signals
No consumer signals collected yet
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

Safety signals
Drug interaction risk — berberine
Berberine inhibits CYP3A4, CYP2D6, and CYP2C9 even at moderate doses. Documented interactions with immunosuppressants, statins, anticoagulants, and antidiabetic drugs. Consult a physician if taking prescription medications.
Read more
Safety flag
berberine: CYP3A4 interactions
Dose or interaction risk detected. See ingredient page for details.
No public lab certificate
Certificate of Analysis not published
Without a public lab certificate, batch purity and potency cannot be independently verified.
No third-party testing
Independent lab verification not disclosed
The brand does not publish evidence of independent batch testing.
Buyer complaints
Trustpilot: customer service complaints on some orders
Recurring themes from consumer review platforms.
Plain English

What’s inside

The main ingredients of this product, in plain language.

Berberine500 mgEvidence A

Plant-derived AMPK activator; near-drug-strength effects on blood sugar and lipids.

Read about Berberine →
Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price
$24
per bottle · 100 servings
Dose vs. research
Below trial dose 56%
of published effective dose
$ / day at studied dose
$0.72
what one effective daily dose costs
$ / g active
$0.48
per gram of active substance
Independently checked

Data verification

COA status
Not public
Evidence grade
A
Per-ingredient breakdown
ABerberine

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Evidence
Berberine
Plant-derived AMPK activator; near-drug-strength effects on blood sugar and lipids.
500 mg 33% of trial dose
1500 mg
3.3 /5
Medium confidence
415 reviews across 2 platforms (2 sources)
Source diversity: 46%
AmazonTrustpilot
Praisegood value bulk powdersupports blood sugar management
Complaintscustomer service complaints on some orders
Last checked: 2026-08-20

Consumer signals

Consumer signals gathered from 2 platforms.

Medium confidence

positive sentiment

Praisegood value bulk powdersupports blood sugar management
Themes

Amazon listing markets BulkSupplements Berberine HCl for metabolic and blood sugar support at a bulk-powder price point.

Compiled from a Amazon product listing listing located during research; verified at build time.

415 reviews · 3.3/5 · mixed sentiment

Praiseproduct effectiveness and puritycompetitive pricing
Complaintscustomer service complaints on some orders
Themes

BulkSupplements' Trustpilot profile shows most reviewers were somewhat happy overall, with quality and pricing praised but some customer service issues noted.

Compiled from a Trustpilot listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Important to know
BerberineStandard berberine has ~5% oral bioavailability. Dihydroberberine and berberine phytosomes absorb better. Split doses across meals (500 mg × 3) to avoid GI upset.

Editorial notes

Standard 500mg berberine HCl powder at a competitive price with no absorption-enhancing co-ingredient (e.g. no dihydroberberine or silymarin pairing that some competitors add).

Brand owners

Spot an error?

If you are the manufacturer or brand owner of Berberine HCl Powder and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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