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Life Extension

Two-Per-Day Multivitamin (capsules/tablets)

Multi/greens · Tablet · 60 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Ingredients listed
5 ingredients listed largest listed: Vitamin C 470 mg
Form
Tablet
List price (catalog, USD)
$24.50
Price per serving
$0.41List price divided by servings per container. A per-day cost only if the label serving is once daily.

Reading notes

  • Multi-ingredient product. Amounts are per ingredient per serving; the product is assessed as one bundle, not as a recommendation for each ingredient.
  • Vitamin amounts shown in µg/mg. Labels may use IU.
Full label record: servings, testing, ingredients
Servings per container
60
Catalog monthly estimate
$12.25
Testing disclosure
Brand lists third-party testing; no public lab certificate listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

IngredientAmount per serving
Vitamin C470 mg
Magnesium100 mg
Zinc25 mg
Alpha-Lipoic Acid25 mg
Quercetin14 mg

What to check on the label

  • Whether every ingredient has its own milligram line, or several are grouped in a 'blend' with one total.
  • How many capsules or scoops make a serving, and how many servings the container holds.
  • Whether the ingredients you care about appear at amounts you would accept on their own. The list below shows each figure.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

7.7/10
Overall score
#1 / 9 in Multi/greens

Tested by independent lab, top 1% value.

Read the evidence (3 studies)
Add to compareVisit brand site →
Watch out
Tier 4
Ingredient RCT (different dose)
The ingredient was tested in an RCT but at a different dose, or only in animals.
See the 3 supporting studies
How we scored this product Show the full breakdown
Dose vs. studies (50%) Why 7.7 of 10. Primary ingredient is Vitamin C (evidence grade A). It delivers 470 mg, inside the studied range of 200–1000 mg. Read the rule → 7.7
Transparency (20%) Why 8.0 of 10. Earned points for independent third-party testing and all doses disclosed. Lost points for no public certificate of analysis. Read the rule → 8.0
Value (10%) Why 9.5 of 10. One day at the trial dose costs about $0.43. That is one of the cheaper options in the catalog (58 of 313 by cost per effective day). Read the rule → 9.5
Formulation (10%) Why 5.0 of 10. No published absorption advantage or disadvantage on file. The default of 5 is not a criticism. Read the rule → 5.0 Default. No absorption data on file.
Safety (5%) Why 7.0 of 10. Baseline 5.0. Third-party testing adds 2.0. Public lab certificate adds 1.5. NSF, USP or Informed Choice certification adds 1.5. Active safety signal subtracts 3.0. Read the rule → 7.0
Community sentiment (5%) Why 9.0 of 10. Sentiment across 13 external review source(s) is mostly positive. Community is a signal about daily use, not proof of effect. Read the rule → 9.0
Composite How this 7.7 is built. 0.50 × 7.7 + 0.20 × 8.0 + 0.10 × 9.5 + 0.10 × 5.0 + 0.05 × 7.0 + 0.05 × 9.0 = 7.7 out of 10. Safety caps applied after. 7.7
7.7 composite
Dose vs. studies50%7.7
Transparency20%8.0
Value10%9.5
Formulation10%5.0
Safety5%7.0
Community5%9.0

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Editorial verdict

Quick verdict

7.7 / 10
Best for
Full trial dose, Budget-friendly
Avoid if
No public lab certificate
Full-dose status
Meets trial dose
Price/month
$12
COA status
Not public
Biggest caveat
No public lab certificate, despite third-party testing.
Nearest alternatives
Catalog snapshot. Check linked sources for current price, label and batch-specific testing.
Price verification
Current price: $24.50
Last price check: Sep 01, 2026
Add to compareVisit brand site →
Layer 2 · Context

Our summary

Life Extension's Two-Per-Day Multivitamin is a dense, ~27-29-ingredient formula that goes well beyond a standard one-a-day multivitamin, including several branded specialty ingredients (Crominex 3+ chromium complex, LycoBeads lycopene, a partially disclosed Bio-Quercetin blend without listed amounts) alongside standard vitamins and minerals at generally moderate-to-generous doses. No clinical trial has tested this exact formulation. The most relevant category-level evidence, the COSMOS trial and its cognitive substudies, which found multivitamin supplementation associated with a cognitive-aging benefit equivalent to roughly 2-3 years of slowed decline in older adults, tested an entirely different commercial product (Centrum Silver, made by Pfizer/Haleon), and this dossier treats that distinction as essential rather than a minor technicality: buyers should understand that this specific LEF formula has not itself been shown to replicate that result. The one disclosed blend without listed amounts in the formula (Bio-Quercetin) is only partially transparent, itemizing 65% of its composition by percentage but leaving the remainder undisclosed. The brand carries a documented FDA warning-letter history for disease-treatment claims made elsewhere on its website, which this dossier discloses at the brand level while noting it could not confirm this specific product's involvement.
In plain language

Why this scored this way

This is our Best All-in-One pick because it does what the label says: covers multiple nutritional bases in one product. Three grade A ingredients (vitamin C, zinc, magnesium) sit at or near their trial doses, and the broad B-complex with active 5-MTHF folate adds real value. At $0.43/day it costs a third of most longevity stacks. The ALA and quercetin add-ins are token doses, but the core formula is solid.

What drives the score up

  • Three grade A ingredients (vitamin C, magnesium, zinc) at or near their trial doses.
  • Broad coverage with 25+ actives including D3, full B-complex with active 5-MTHF folate, and chelated minerals.
  • Tested by independent lab, and at $0.43/day it's one of the best-value multivitamins available.
  • Uses active folate (5-MTHF) instead of cheap folic acid, which matters for people with MTHFR variants.

What drags it down

  • No public lab certificate, despite third-party testing.
  • ALA at 25mg and quercetin at 14mg are far below their trial doses. These are marketing add-ins, not functional doses.
  • Community score is 6.0 (neutral) with no reviews yet.

Why you'd choose it

  • You want one product that covers foundational nutrition broadly instead of buying 5 separate bottles.
  • You want a multivitamin with active folate and chelated minerals at real doses.

Why you might skip it

  • You want a public lab certificate to verify the label.
  • You're buying it for the ALA or quercetin content. Those are present at token doses only.
Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Vitamin C

Correcting deficiency is important; megadoses rarely add benefit.

4 landmark RCTs · US: Dietary supplement · EU: Food supplement
Magnesium

One of the most common deficiencies; corrects sleep, muscle cramps, and blood pressure.

5 landmark RCTs · US: Dietary supplement · EU: Food supplement, health claims authorised
Zinc

Essential mineral for immunity and skin; watch out for copper depletion.

3 landmark RCTs · US: Dietary supplement · EU: Food supplement
Alpha-Lipoic Acid

Mitochondrial cofactor with genuine efficacy in diabetic neuropathy.

4 landmark RCTs · US: Dietary supplement · EU: Restricted in Italy/EU (safety review); food supplement elsewhere
Quercetin

Best-studied 'senolytic' ingredient, though evidence is early.

4 landmark RCTs · US: Dietary supplement · EU: Food supplement (extract-dependent)

Full ingredient breakdown

Every active in this formula, its declared dose per serving, the dose used in the primary human trial, how much of that trial dose this product delivers, and the evidence grade for the ingredient itself.

IngredientDose / servingResearch dose% of researchEvidence grade
Vitamin C470 mg500 mg94%A
Magnesium100 mg300 mg33%A
Zinc25 mg15 mg167%A
Alpha-Lipoic Acid25 mg600 mg4%A
Quercetin14 mg500 mg3%B

Percentages are dose per serving ÷ primary trial dose. Below 50% means the formula is unlikely to reproduce the trial outcome for that active. Grade A = multiple large human RCTs. Grade F = no human evidence. How grades work. Full glossary →

Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
100% of trial dose
Meets or exceeds the published effective dose
Cost at trial dose
$0.43/day at trial dose
What one effective daily dose actually costs
Transparency
8.0/10 · No public lab certificate
Independent batch testing confirmed
Consumer signals
14,560 reviews across platforms · 4.7/5 · high confidence
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

No public lab certificate
Certificate of Analysis not published
Without a public lab certificate, batch purity and potency cannot be independently verified.
Buyer complaints
Amazon: Nausea and stomach discomfort without food; Amazon: Unpleasant taste and pungent odor
Recurring themes from consumer review platforms.
Plain English

What’s inside

The main ingredients of this product, in plain language.

Vitamin C470 mgEvidence A

Correcting deficiency is important; megadoses rarely add benefit.

Read about Vitamin C →
Magnesium100 mgEvidence A

One of the most common deficiencies; corrects sleep, muscle cramps, and blood pressure.

Read about Magnesium →
Zinc25 mgEvidence A

Essential mineral for immunity and skin; watch out for copper depletion.

Read about Zinc →
Alpha-Lipoic Acid25 mgEvidence A

Mitochondrial cofactor with genuine efficacy in diabetic neuropathy.

Read about Alpha-Lipoic Acid →
Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price
$24
per bottle · 60 servings
Dose vs. research
of trial dose 100%
of published effective dose
$ / day at studied dose
$0.43
what one effective daily dose costs
$ / g active
$0.64
per gram of active substance
Independently checked

Data verification

COA status
Not public
Evidence grade
AAAAB
Per-ingredient breakdown
AVitamin C
AMagnesium
AZinc
AAlpha-Lipoic Acid
BQuercetin

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Evidence
470 mg 94% of trial dose
500 mg
100 mg 33% of trial dose
300 mg
25 mg 167% of trial dose
15 mg
25 mg 4% of trial dose
600 mg
14 mg 3% of trial dose
500 mg
4.5 /5
High confidence Strong value signal
15,279 reviews across 3 platforms (3 sources)
Source diversity: 69%
AmazonTrustpilotiHerb
PraiseEnergy boost and reduced lethargyHigh-quality bioavailable formulation
ComplaintsNausea and stomach discomfort without foodUnpleasant taste and pungent odor
Last checked: 2026-08-20

Consumer signals

4.7 out of 5 across 14,560 verified reviews on 5 platforms.

High confidence

Consumer sentiment is overwhelmingly positive across 14,560+ Amazon reviews and iHerb reviews. The product is consistently praised for energy, formulation quality, and value. The main complaint pattern (nausea without food) is a known multivitamin effect, not specific to this brand.

Amazon

14,560 reviews · 4.7/5 · positive sentiment

PraiseEnergy boost and reduced lethargyHigh-quality bioavailable formulationExcellent value for money
ComplaintsNausea and stomach discomfort without foodUnpleasant taste and pungent odorHeartburn reported by some users

Amazon aggregates multiple variant listings (tablets 2,783 + capsules 5,020 reviews). Rating and count from the main capsule listing.

iHerb

positive sentiment

Praise

Comprehensive formula with bioavailable B vitamins, zinc, selenium

Increased energy, focus, mood, and overall well-beingConvenient two-tablets-a-day dosing with good value
ComplaintsPungent odor of tabletsNeon-yellow urine from B vitamin metabolismBenefits may not be immediately noticeable

iHerb review page rendered dynamically; exact rating and count not extractable from page HTML. Themes compiled from visible review excerpts.

Trustpilot

719 reviews · 4.3/5

Vendor site

1,385 reviews · 4.8/5

Vendor curates its own reviews; treat as least reliable of the sources listed here.

Reddit r/Supplements

2 threads discussed · positive sentiment

Themes

people notice the unusually high B-vitamin doses (B12 at 25,000% DV) and ask whether that's a feature or a concern

some report a real energy boost tied specifically to the B-complex or magnesium content

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

Independent external anchors

Public sources on this same product, unrelated to NO1GEVITY. NIH DSLD is the US government's registered label database (shown verbatim). SuppCo.com is a separate, unaffiliated commercial site with no partnership or data-sharing arrangement with us. NO1GEVITY scores are computed independently of both.

Unaffiliated third-party site
SuppCo.com

SuppCo is a separate, unaffiliated supplement-tracking site with no partnership, data-sharing agreement, or business relationship with NO1GEVITY. We are not endorsed by them and they do not endorse us. The two facts below are individually verified against the manufacturer or NSF; the outbound link is provided only so readers can independently cross-check on a third-party site if they want to.

Tested by independent lab, YesNSF certified, Yes
NIH DSLD registered label
DSLD ID 328754, UPC 7 37870 23141 7
Serving size2 Capsule(s)
Servings per container60
Supplement Facts panel, verbatim
Vitamin A1500 mcg RAE167% DV
Vitamin C470 mg522% DV
Vitamin D350 mcg250% DV
Vitamin E67 mg447% DV
Thiamine75 mg6250% DV
Riboflavin50 mg3846% DV
Niacin50 mg NE313% DV
Vitamin B675 mg4412% DV
Folate680 mcg DFE170% DV
Vitamin B12300 mcg12500% DV
Biotin300 mcg1000% DV
Pantothenic Acid50 mg1000% DV

What others say, with a source hierarchy

We treat external opinion very differently depending on where it comes from. Tier A is our strongest signal. Tier C is background sentiment only. Tier Rejected is what we excluded, listed openly so you can see what we discarded.

These reviews are aggregated from third-party sources, not written by NO1GEVITY. Each entry shows its source, retrieval date, and whether the source has an affiliate or paid relationship. We do not edit reviews to change their meaning. Disclosure policy.

Tier A

Independent deep reviews, lab tests, certificates of analysis

Our strongest external evidence. Long-form independent reviews, physical-product lab work, and third-party certifications.

ConsumerLab.com, Multivitamin/Multimineral Supplements Review
No affiliate relationship Not a paid placement

The multivitamin category as a whole has a nontrivial label-accuracy failure rate in independent testing, a relevant general caution, though not a confirmed finding for this specific product.

Finding: ConsumerLab's ongoing multivitamin category testing has, across various rounds, found a meaningful minority of tested multivitamin products fail to meet label claims for at least one ingredient; specific results for this exact Life Extension Two-Per-Day SKU in the most recent round were not confirmed in this research pass.
How we use it: Used as category-level, not product-specific, quality caution.
FDA Warning Letter to Life Extension Foundation Buyers Club, Inc.
No affiliate relationship Not a paid placement

A genuine regulatory compliance history item for the brand; this dossier could not confirm this specific multivitamin product was among those cited in the letter.

Finding: FDA cited disease-treatment/prevention claims made on lifeextension.com for certain products as rendering them unapproved drugs under the FD&C Act, dated February 1, 2017.
How we use it: Disclosed as brand-level regulatory history context, explicitly caveated as not confirmed to be product-specific.
Tier B

Registered dietitians and physicians, without affiliate ties

Credentialed commentary from clinicians who disclose no paid relationship. Useful as supporting critique but not a substitute for a clinical outcome trial.

Trustpilot (lifeextension.com aggregate)
No affiliate relationship Not a paid placement

General brand reputation signal only.

Finding: Brand-level Trustpilot sentiment for Life Extension is generally mixed-to-positive, reflecting overall customer-service and product-satisfaction experience rather than this specific SKU's efficacy.
How we use it: Used as brand-level customer-service context, not product-specific efficacy evidence.
Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence, what actually backs this product

Longevity brands rarely test their exact finished product. We separate what's tested from what's inferred.

Strongest evidence tier
Tier 4Ingredient RCT (different dose)
4 studies mapped
Tier 0No source
Quercetin bioavailability enhancement via fenugreek galactomannan complexation
Multiple (ingredient-supplier-cited pharmacokinetic research on the branded quercetin-galactomannan complex used in Bio-Quercetin) · 2016 · Various (industry/ingredient-supplier-cited) · Fenugreek-galactomannan-complexed quercetin vs. unformulated quercetin, single-dose comparison · Single-dose pharmacokinetic sampling
ingredient-levelnot peer-reviewed
Ingredient-supplier-cited data claims substantially improved plasma quercetin bioavailability versus unformulated quercetin.
This dossier could not independently locate and verify the primary peer-reviewed publication behind this bioavailability claim in this research pass; it is included with an explicit sourcing caveat rather than omitted, and should be treated as an industry-cited, not independently confirmed, data point pending further verification.
Conflicts: Likely funded or supplied by the branded ingredient's manufacturer; not independently confirmed
Source →
Tier 4Ingredient RCT (different dose)
Multivitamin Supplementation and Cognitive Function in Older Adults (COSMOS-Web / COSMOS-Mind)
Baker LD, Manson JE, Rapp SR, et al. · 2023 · Alzheimer's & Dementia / American Journal of Clinical Nutrition · Centrum Silver multivitamin (a DIFFERENT commercial product, manufactured by Pfizer/Haleon, NOT Life Extension's Two-Per-Day formula) vs. placebo · 3 years
ingredient-levelpeer-reviewed
Multivitamin group showed a statistically significant improvement in memory equivalent to approximately 3.1 years of slowed age-related cognitive decline versus placebo.
CRITICAL PRODUCT-MISMATCH FLAG: this widely cited trial and its parent study (COSMOS, NCT02422745, 21,442 participants, 3.6 years) tested Centrum Silver, a specific different commercial multivitamin with its own distinct formulation and dosing, not Life Extension's Two-Per-Day. This dossier includes it only as ingredient-category evidence that daily multivitamin use in older adults may plausibly support cognitive function, a real and relevant finding for the general question of 'do multivitamins help older adults', but it must not be read as evidence FOR this specific 27-29-ingredient LEF formulation, whose dosing and ingredient list differ substantially from Centrum Silver's.
Conflicts: COSMOS trial supported in part by Pfizer Consumer Healthcare (maker of Centrum), which donated study pills; NIH/NIA also funded the trial
Source →
Tier 4Ingredient RCT (different dose)
Meta-analysis of the COSMOS cognitive substudies (COSMOS-Mind, COSMOS-Web, COSMOS-Clinic)
Yeung SLA, Baker LD, et al. · 2024 · Alzheimer's & Dementia · Centrum Silver multivitamin (same different product as above) vs. placebo · Up to 3 years across pooled substudies
ingredient-levelpeer-reviewed
Pooled analysis found a global cognition benefit equivalent to approximately 2 years of slowed cognitive aging, consistent across the three substudies.
Same critical caveat as above: this strengthens the ingredient-category (multivitamin-general) cognitive signal but remains evidence about Centrum Silver, not Life Extension's formula, and should not be presented to consumers as if it were product-specific.
Conflicts: Same as parent COSMOS trial, Pfizer Consumer Healthcare involvement
Source →
Tier 4Ingredient RCT (different dose)
COSMOS trial primary cardiovascular and cancer outcomes
Sesso HD, Rist PM, Aragaki AK, et al. · 2022 · American Journal of Clinical Nutrition · n=21442 · Centrum Silver multivitamin (different product than this one) vs. placebo · 3.6 years median
ingredient-levelpeer-reviewed
No statistically significant reduction in major cardiovascular events or total invasive cancer incidence versus placebo; a possible signal for reduced lung cancer was noted but not the primary powered endpoint.
Reinforces that even at the ingredient-category level, general multivitamin supplementation in this population did not demonstrate the broad chronic-disease-prevention benefits sometimes implied by multivitamin marketing, again on a different product than this LEF formula.
Conflicts: Pfizer Consumer Healthcare donated study pills; NIH/NIA funded the trial
Source →
Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Vitamin CVitamin C umbrella review 2022 (76 meta-analyses)
Vitamin CVitamin C + telomere length 2023 (NHANES)
Vitamin CVitamin C and CVD 2020 (Antioxidants)
Vitamin CCochrane: Vitamin C for common cold
MagnesiumMagnesium + CVD meta-analysis 2019 (544,581)
MagnesiumMagnesium + vascular function 2020 meta-analysis
MagnesiumMagnesium + cognitive health 2024 (Adv Nutr)
MagnesiumMagtein RCT 2026 (N=100)
MagnesiumMagnesium + T2D meta-analysis 2007 (286,668)
ZincZinc + immune meta-analysis 2022 (35 RCTs)
ZincZinc + elderly infections RCT 2007 (AJCN)
ZincZinc lozenges + common cold 2017 meta-analysis
Alpha-Lipoic AcidALADIN Study (Ziegler 1995)
Alpha-Lipoic AcidALA glycemic meta-analysis 2021 (28 RCTs)
Alpha-Lipoic AcidALA inflammatory meta-analysis 2019 (41 studies)
Alpha-Lipoic AcidALA + T2D RCT 2022 (16 RCTs)
QuercetinHickson et al. 2019 (senolytics in humans)
QuercetinQuercetin + blood pressure 2016 meta-analysis
QuercetinQuercetin + blood pressure 2022 meta-analysis
QuercetinD+Q pilot trial 2025 (F1000Research)

Claim check, vendor claims vs. our reading of the evidence

Not medical advice. We list the strongest claims made by the brand and check each against traceable evidence.

Partially Supported
“Comprehensive nutrient-insurance formula supporting healthy aging and cognitive function”
The most relevant large-scale evidence for a general multivitamin cognitive benefit (COSMOS/COSMOS-Web/COSMOS-Mind, finding a benefit equivalent to 2-3 years of slowed cognitive aging) tested a completely different commercial product, Centrum Silver, not this Life Extension formulation. This is meaningful ingredient-category evidence that daily multivitamin use in older adults may plausibly support cognition, but it should not be presented as evidence this specific 27-29-ingredient LEF formula produces the same effect, the two products' ingredient lists and doses differ substantially, and no trial has tested this exact formulation.
Vendor source
Partially Supported / Partially Unverifiable
“Bio-Quercetin blend without listed amounts offers enhanced quercetin absorption”
The label does disclose that the 14 mg blend without listed amounts delivers approximately 35% quercetin (~5 mg) and 30% galactomannans (~4 mg) by percentage, a partial disclosure that is better than a fully opaque blend, but the remaining ~35% of the blend's composition is not itemized, and this dossier could not independently locate and verify the primary peer-reviewed bioavailability study behind the enhanced-absorption claim in this research pass.
Vendor source
Unverified
“Supports healthy aging with a scientifically formulated, comprehensive nutrient profile”
'Scientifically formulated' and 'comprehensive' are marketing language, not independently verifiable claims; while each individual vitamin/mineral has an established nutritional rationale, no outcomes trial exists on this exact 27-29-ingredient combination as formulated, and the primary category-level trial evidence (COSMOS) tested a different product entirely.
Vendor source
Unverified In This Research Pass
“Chromium delivered via Crominex 3+ for enhanced glucose metabolism support”
Crominex 3+ is a named branded ingredient (not an anonymous blend without listed amounts), which is a transparency positive, but this dossier did not independently locate and verify the specific clinical trials behind Crominex 3+'s glucose-metabolism claims within the available research budget; treated as an open item rather than asserted as either supported or unsupported.
Vendor source

Regulatory status

Rules change often. We record when we last verified each row. See the full regulatory timeline →

What we could not verify

We list this openly. If a claim isn't backed by a source we can trace, we'd rather flag it than repeat it.

  • No outcomes trial exists on this exact 27-29-ingredient Life Extension formulation; the most relevant large multivitamin trial (COSMOS and its cognitive substudies) tested a different commercial product (Centrum Silver) with a different ingredient list and dosing, this is a category-evidence-only situation, prominently flagged in evidence_registry and claim_check.
  • The remaining ~35% composition of the 'Bio-Quercetin Proprietary Blend' beyond the disclosed quercetin (35%) and galactomannan (30%) percentages is not itemized on the label.
  • The primary peer-reviewed publication behind the vendor's fenugreek-galactomannan quercetin bioavailability-enhancement claim was not independently located and verified in this research pass.
  • Whether this specific Two-Per-Day multivitamin product was named in Life Extension's February 2017 FDA warning letter (which cited disease-claim violations on other lifeextension.com products) was not confirmed.
  • The EU/UK formulation sold via Life Extension Europe has different dosing structure from the US version reviewed here; this dossier reviews the US SKU only and did not conduct a full ingredient-by-ingredient comparison of the EU variant.
  • No independent third-party lab test (ConsumerLab, Labdoor) specific to this SKU's potency across all ~27-29 listed actives was located.
  • Trustpilot aggregator
    4.3/5698 reviews

    This is a brand-level customer-service profile for life-extension; it does not isolate Two-Per-Day Multivitamin (capsules/tablets).

    verified 2026-08-07Open source →
  • Reddit r/Supplements community forum
    mixed sentiment

    Community discussion exists around the Two-Per-Day Multivitamin, with positive comments about its potent formulation alongside concerns that the labeled doses are high and many users take only one capsule. No single Reddit thread is treated as a representative product review.

    no direct URLchecked 2026-08-07
  • Life Extension on-site reviews own platform

    The product page includes first-party reviews without a public aggregate rating or count.

    verified 2026-08-07Open source →
  • Amazon customers aggregator

    An Amazon listing for this exact product was located. The product URL is not retained because marketplace listings can change.

    no direct URLchecked 2026-08-07
Important to know
Vitamin CHigh doses cause GI upset. Buffered forms gentler. Liposomal marketing typically overstated for chronic use.
MagnesiumMagnesium oxide has ~4% absorption and mostly acts as a laxative. Always check the salt form, not just 'magnesium'.
ZincChronic >50 mg/day causes copper deficiency.
Alpha-Lipoic AcidCheap 'ALA' products sell the racemic form (50% inactive). Look for 'R-ALA' or 'R-alpha-lipoic acid'. Take on empty stomach.
QuercetinPlain quercetin dihydrate has poor absorption. Phytosome forms deliver 10 to 20× more into blood.

Editorial notes

A genuinely high-potency, budget-friendly multivitamin (25+ actives in 2 tablets/day) with 2000 IU D3, full B-complex with active 5-MTHF folate, chelated minerals, and small add-ins of alpha lipoic acid and quercetin; solid 'foundational' longevity multi at one of the lowest per-serving costs in the premium supplement category.

Go deeper

Where this sits

Actives inside
Vitamin CMagnesiumZincAlpha-Lipoic AcidQuercetin
Category
See all in Multi/greens →
Ranking
See top 10 Magnesium supplements →
Brand
Life Extension profile →
Add to compare Visit brand site →
Brand owners

Spot an error?

If you are the manufacturer or brand owner of Two-Per-Day Multivitamin (capsules/tablets) and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with novoslabs.com
Thorne HealthTech
Basic Nutrients 2/Day
Multi/greens
Ingredients listed
5 ingredients listedlargest listed: Magnesium 20 mg
Price per serving
$1.07$32.00 · 30 servings
Testing
3rd-party listed · no public lab certificate

Multi-ingredient bundle

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 7.1/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$1.07
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.thorne.com
Same maker

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Price per serving
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Testing
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Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 8.0/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

70%
of trial dose
$1.43
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.lifeextension.com
NAD+ booster
Precursor per serving
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Price per serving
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Testing
3rd-party listed · no public lab certificate

Undisclosed amounts noted

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 7.8/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.80
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.lifeextension.com
Mineral
Mineral per serving
Magnesium 144 mgElemental vs compound: check label
Price per serving
$1.00$30.00 · 30 servings
Testing
3rd-party listed · no public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 7.7/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

72%
of trial dose
$2.08
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.lifeextension.com
Life Extension
Super Ubiquinol CoQ10
Mitochondrial
Active per serving
CoQ10 100 mgSoftgel · 60 servings
Price per serving
$0.62$37.50 · 60 servings
Testing
3rd-party listed · no public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 7.2/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$1.25
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.lifeextension.com
Life Extension
Berberine
Metabolic
Active per serving
Berberine 510 mgCapsule · 60 servings
Price per serving
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Testing
3rd-party listed · no public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.5/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

57%
of trial dose
$1.21
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.lifeextension.com