Cautiously positive: Innerbody's medically-reviewed staff assessment concludes Tru Niagen is a well-researched, FDA-acknowledged-safe NR supplement, but flags an unresolved, contested theoretical concern about NR potentially exacerbating tumor growth in cancer patients (citing mixed preclinical evidence) and recommends physician consultation for anyone with a cancer history.
Tru Niagen 300 mg
Label snapshot
What the label says
What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.
- Precursor per serving
- NR 300 mg
- Form
- Capsule
- List price (catalog, USD)
- $45.00
- Price per serving
- $1.50List price divided by servings per container. A per-day cost only if the label serving is once daily.
Full label record: servings, testing, ingredients
- Servings per container
- 30
- Serving size (label)
- 0.3 g
- Catalog monthly estimate
- $45.00
- Testing disclosure
- Brand lists third-party testing; no public lab certificate listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Ingredients as listed
| Ingredient | Amount per serving |
|---|---|
| NR | 300 mg |
What to check on the label
- Which precursor is named. NMN and NR are different molecules and are not interchangeable milligram for milligram.
- Whether the milligram figure is per capsule or per serving of several capsules. The catalog records per serving.
- Whether a certificate of analysis (CoA) is published for the batch you buy. The catalog only records whether the brand lists one.
- Added ingredients (resveratrol, TMG, quercetin) are listed with their own amounts below. Read them separately.
Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.
Editorial score and research-dose calculations
These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.
Full trial dose, tested by independent lab.
Read the evidence (2 studies)See the 2 supporting studies
- Martens et al. 2018 (NR)6 weeks of 500 mg twice daily lowered systolic blood pressure in older adults with elevated BP. Studied at 500 mg. This product: 300 mg.
- Dellinger et al. 2017 (NR)8 weeks at 100 to 1000 mg/day dose-dependently raised NAD+ in blood. Studied at 1000 mg. This product: 300 mg.
How we scored this product Show the full breakdown
Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.
This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.
Quick verdict
Our summary
Why this scored this way
This Tru Niagen (ChromaDex) Tru Niagen 300 mg scores 7.6, making it a strong scorer. It delivers 300mg of NR, inside the studied range of 100–1000mg with grade B evidence (promising human data, not yet comprehensive). At $1.50/day it's among the more expensive options in NAD+ booster.
What drives the score up
- Dose-evidence score of 8.0 reflects good alignment with trial doses.
- Tested by independent lab (transparency 8.0).
- NR is dosed at the full research level with grade B evidence (promising human data, not yet comprehensive).
What drags it down
- No public lab certificate available for independent verification.
Why you'd choose it
- You want a reasonably priced nad+ booster product.
- You want NR from a Tru Niagen (ChromaDex) product.
- You want a tested by independent lab product.
Why you might skip it
- You want a product with a publicly available CoA.
- You want better value (this is $1.50/day with a value score of 8.0).
Question 1
Does the molecule work?
Does the molecule work?
The science behind each active ingredient, independent of which brand sells it.
The NAD+ precursor with the strongest safety file and EU approval.
Question 2
Is this bottle good?
Is this bottle good?
The specific product: dose, price, transparency, and what buyers report.
Question 3
What's the catch?
What's the catch?
Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.
What’s inside
The main ingredients of this product, in plain language.
Product data & verification
Hard numbers and independently checked status. Expand each block for its source.
The numbers
Data verification
Per-ingredient breakdown
All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.
What's inside
Consumer signals
4.38 out of 5 across 2 verified reviews on 4 platforms.
Medium confidenceConsumer sentiment compiled from 3 public sources (Examine.com, Labdoor, Trustpilot).
4.35/5 · positive sentiment
Labdoor NAD+ ranking: Tru Niagen top-3 for identity and purity.
Compiled from a Labdoor listing located during manual research; not independently re-verified against the live page at build time. Rating converted from 100-point to 5-point scale.
positive sentiment
Examine highlights Niagen® NR as the most heavily-studied NAD+ booster in humans.
Compiled from an Examine.com listing located during manual research; not independently re-verified against the live page at build time.
10 reviews · 4.4/5 · positive sentiment
4.4/5. Users like the safety data; occasional complaints about auto-ship.
Compiled from a Trustpilot listing located during manual research; not independently re-verified against the live page at build time.
These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.
What others say, with a source hierarchy
We treat external opinion very differently depending on where it comes from. Tier A is our strongest signal. Tier C is background sentiment only. Tier Rejected is what we excluded, listed openly so you can see what we discarded.
These reviews are aggregated from third-party sources, not written by NO1GEVITY. Each entry shows its source, retrieval date, and whether the source has an affiliate or paid relationship. We do not edit reviews to change their meaning. Disclosure policy.
Independent deep reviews, lab tests, certificates of analysis
Our strongest external evidence. Long-form independent reviews, physical-product lab work, and third-party certifications.
ConsumerLab's independent lab testing supports that the genuine Tru Niagen product meets its label claim for NR content, in contrast to a majority of competing NR supplements tested in the same sweep, but the existence of counterfeit Tru Niagen products in the market is a real risk ConsumerLab has flagged for buyers purchasing outside official channels.
General ingredient-level review (not a product-specific test) concluding NR is a reasonably well-tolerated vitamin B3 form marketed for anti-aging purposes, with mild possible side effects (nausea, fatigue, headache, GI discomfort) reported by some users, and with benefits still considered unproven for humans despite promising animal data.
Aggregated sentiment (Trustpilot, Reddit)
Mood indicator only. We never use aggregate stars as evidence of efficacy.
Mixed-to-negative sentiment, but the sample size (N=10) is far too small to be statistically meaningful and falls well below the brief's N>500 threshold for Tier B treatment of Trustpilot data.
Middling independent sentiment from UK customers, with one favorable review specifically citing lowered cholesterol and blood pressure alongside no side effects, an individual anecdote, not a controlled measurement.
Large sample size skews positive, consistent with typical Amazon supplement review patterns, but Amazon reviews are known to be susceptible to incentivized/manipulated reviews and lack any testing methodology; one critical review specifically noted a subtle, hard-to-notice effect relative to the product's price.
Community threads and aggregate ratings
Additional public mentions we located, kept separate from the deep independent reviews above.
Labdoor NAD+ ranking: Tru Niagen top-3 for identity and purity.
Examine highlights Niagen® NR as the most heavily-studied NAD+ booster in humans.
4.4/5. Users like the safety data; occasional complaints about auto-ship.
Evidence, claims & regulation
Published evidence, claim checks, regulatory status and what could not be verified.
Evidence, what actually backs this product
Longevity brands rarely test their exact finished product. We separate what's tested from what's inferred.
Research behind this product
The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.
Claim check, vendor claims vs. our reading of the evidence
Not medical advice. We list the strongest claims made by the brand and check each against traceable evidence.
Regulatory status
Rules change often. We record when we last verified each row. See the full regulatory timeline →
What we could not verify
We list this openly. If a claim isn't backed by a source we can trace, we'd rather flag it than repeat it.
- No public, batch-level Certificate of Analysis was located on the vendor's site for this specific 30-count 300mg SKU during this review.
- The vendor's claim that NIAGEN 'is featured in more than 65% of registered, ongoing, or completed trials on nicotinamide riboside' could not be independently verified against a live ClinicalTrials.gov search in this pass.
- Exact manufacturing location/facility for the finished capsule (as opposed to the NIAGEN raw ingredient, which is manufactured by W.R. Grace) was not confirmed.
- ConsumerLab's full test results for this specific product (exact measured NR content vs. the 300 mg label claim) sit behind a paywall; only summary/secondary-source figures (reportedly ~303 mg found vs. 300 mg labeled) were available, and could not be verified against the primary ConsumerLab report in this pass.
- The vendor's on-site customer survey (92% agree the product is important to their healthy-aging journey, 85% would recommend it, based on n=118 self-selected respondents at https://www.truniagen.com/pages/reviews) is a marketing-controlled data source, not an independent survey, and should not be treated as equivalent to independent review platforms.
- Direct fetch of the primary vendor product page (https://www.truniagen.com/products/tru-niagen-30-count-300mg/) timed out during this review; label and pricing data were cross-verified via retailer listings and vendor subdomains (support.truniagen.com, pages.truniagen.com, pro.truniagen.com) instead of the primary page rendering directly.
-
Trustpilot aggregator2.9/510 reviews
This is a brand-level customer-service profile for tru-niagen; it does not isolate Tru Niagen 300 mg.
verified 2026-08-07Open source → -
Reddit r/Supplements community forummixed sentiment
Community discussion exists around Tru Niagen, with reports of improved energy and recovery alongside concerns about high dosing and cost. No single Reddit thread is treated as a representative product review.
no direct URLchecked 2026-08-07 -
Tru Niagen on-site testimonials own platform
The public Tru Niagen page presents customer testimonials but no aggregate rating or count.
verified 2026-08-07Open source →
Editorial notes
The ChromaDex flagship. Extensive safety file, marketed heavily at the general consumer.
Where this sits
Spot an error?
If you are the manufacturer or brand owner of Tru Niagen 300 mg and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.
We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.
Request a correction →Similar products
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Multi-ingredient bundle
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