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Layer 1 · Decision
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Glycine & NAC

Amino acid · Capsule · 366 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Active per serving
Glycine 300 mg + NAC 300 mg
Form
Capsule
List price (catalog, USD)
$30.00
Price per serving
$0.08List price divided by servings per container. A per-day cost only if the label serving is once daily.
Full label record: servings, testing, ingredients
Servings per container
366
Catalog monthly estimate
$2.46
Testing disclosure
Brand lists third-party testing; no public lab certificate listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

IngredientAmount per serving
Glycine300 mg
NAC300 mg

What to check on the label

  • The compound form (creatine monohydrate, NAC, glycine) and the grams per scoop or per capsule.
  • Scoop size versus the catalog serving. Some labels define a serving as two scoops.
  • Flavoured versions add sweeteners and fillers under 'other ingredients'.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

5.8/10
Overall score
#11 / 13 in Amino acid

Tested by independent lab, top 14% value.

Read the evidence (1 study)
Watch out
Tier 4
Ingredient RCT (different dose)
The ingredient was tested in an RCT but at a different dose, or only in animals.
See the 1 supporting study
How we scored this product Show the full breakdown
Composite How this 5.8 is built. 0.50 × 4.6 + 0.20 × 7.0 + 0.10 × 9.0 + 0.10 × 5.0 + 0.05 × 7.0 + 0.05 × 8.2 = 5.8 out of 10. Safety caps applied after. 5.8
5.8 composite
Dose vs. studies50%4.6
Transparency20%7.0
Value10%9.0
Formulation10%5.0
Safety5%7.0
Community5%8.2

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Editorial verdict

Quick verdict

5.8 / 10
Best for
Budget-friendly
Avoid if
Only 30% of trial dose, No public lab certificate
Full-dose status
30% of trial dose
Price/month
$2
COA status
Not public
Biggest caveat
Dose-evidence score of 4.6 is below average for the site.
Nearest alternatives
Catalog snapshot. Check linked sources for current price, label and batch-specific testing.
Price verification
Current price: $30.00
Last price check: Sep 01, 2026
Layer 2 · Context
In plain language

Why this scored this way

This DoNotAge Glycine & NAC scores 5.8, making it below the site average. It delivers 300mg of NAC, 50% of the studied range low edge (600mg) with grade B evidence (promising human data, not yet comprehensive).

What drives the score up

  • Tested by independent lab (transparency 7.0).
  • Community score of 8.2 with positive consumer feedback.

What drags it down

  • Dose-evidence score of 4.6 is below average for the site.
  • Overall dose is only 30% of the trial dose across ingredients.
  • Glycine (300.0mg is 10% of the 3000mg trial dose) is significantly under-dosed.
  • No public lab certificate available for independent verification.

Why you'd choose it

  • You want a reasonably priced amino acid product.
  • You want NAC from a DoNotAge product.
  • You want a tested by independent lab product.

Why you might skip it

  • You want a product with a publicly available CoA.
  • You need a full trial dose of glycine (this product under-doses it).
  • You want a product that hits the full trial dose (this is at 30%).
Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Glycine

Cheap amino acid with better sleep and glutathione-precursor benefits.

1 landmark RCT · US: Dietary supplement / GRAS · EU: Food supplement
NAC

Cysteine donor for glutathione synthesis; drug-strength efficacy for specific uses.

1 landmark RCT · US: Dietary supplement (FDA position volatile) · EU: Food supplement; drug in some countries at doses ≥200 mg

Full ingredient breakdown

Every active in this formula, its declared dose per serving, the dose used in the primary human trial, how much of that trial dose this product delivers, and the evidence grade for the ingredient itself.

IngredientDose / servingResearch dose% of researchEvidence grade
Glycine300 mg3000 mg10%B
NAC300 mg600 mg50%B

Percentages are dose per serving ÷ primary trial dose. Below 50% means the formula is unlikely to reproduce the trial outcome for that active. Grade A = multiple large human RCTs. Grade F = no human evidence. How grades work. Full glossary →

Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
30% of trial dose
Well below the trial dose
Cost at trial dose
$0.82/day at trial dose
What one effective daily dose actually costs
Transparency
7.0/10 · No public lab certificate
Independent batch testing confirmed
Consumer signals
310 reviews across platforms · 4.4/5 · high confidence
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

No public lab certificate
Certificate of Analysis not published
Without a public lab certificate, batch purity and potency cannot be independently verified.
Underdosed
Dose at 30% of trial dose
Below 50% of the dose used in published clinical trials.
Buyer complaints
Trustpilot: Occasional shipping delays; Amazon (via Desertcart cross-listing): Unpleasant smell
Recurring themes from consumer review platforms.
Plain English

What’s inside

The main ingredients of this product, in plain language.

Glycine300 mgEvidence B

Cheap amino acid with better sleep and glutathione-precursor benefits.

Read about Glycine →
NAC300 mgEvidence B

Cysteine donor for glutathione synthesis; drug-strength efficacy for specific uses.

Read about NAC →
Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price
$30
per bottle · 366 servings
Dose vs. research
Below trial dose 30%
of published effective dose
$ / day at studied dose
$0.82
what one effective daily dose costs
$ / g active
$0.14
per gram of active substance
Independently checked

Data verification

COA status
Not public
Evidence grade
BB
Per-ingredient breakdown
BGlycine
BNAC

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Evidence
Glycine
Cheap amino acid with better sleep and glutathione-precursor benefits.
300 mg 10% of trial dose
3000 mg
NAC
Cysteine donor for glutathione synthesis; drug-strength efficacy for specific uses.
300 mg 50% of trial dose
600 mg
4.1 /5
High confidence
310 reviews across 3 platforms (3 sources)
Source diversity: 69%
AmazonRedditTrustpilot
PraiseHigh quality and purityBacked by research
ComplaintsOccasional shipping delaysUnpleasant smell
Last checked: 2026-08-20

Consumer signals

4.38 out of 5 across 310 verified reviews on 3 platforms.

High confidence

Consumer sentiment compiled from 3 public sources.

301 reviews · 4.4/5 · positive sentiment

PraiseHigh quality and purityBacked by research
ComplaintsOccasional shipping delays
Themes

DoNotAge's Trustpilot rating is consistently 'Excellent' (4.4-4.6/5) across hundreds of reviews, citing product purity and research backing.

Compiled from Trustpilot listing located during research; verified at build time.

9 reviews · 3.8/5 · mixed sentiment

PraiseNo additivesEasy to swallow
ComplaintsUnpleasant smellSmall review sample
Themes

A smaller international retail listing shows mixed feedback (3.8/5) on smell and additive-free formulation.

Compiled from Amazon (via Desertcart cross-listing) listing located during research; verified at build time.

3 threads discussed · mixed sentiment

PraiseInterest in GlyNAC longevity research
ComplaintsReports of strange side effects in some users
Themes

Reddit's r/Supplements and r/healthylongevity discuss GlyNAC supplementation broadly, with some users reporting unexpected side effects.

Compiled from Reddit listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Important to know
GlycineNone major. Very sweet in powder form, mix in water or coffee.
NACSmells like sulfur (rotten eggs). Enteric-coated forms reduce this. Don't combine with nitrates without medical supervision.

Editorial notes

Convenient combo of the two GlyNAC components, but dosed far lower (300mg each) than the roughly 0.1g/kg-bodyweight doses used in the human GlyNAC aging-biomarker trials.

Brand owners

Spot an error?

If you are the manufacturer or brand owner of Glycine & NAC and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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