Basics: short version, verdict first People Molecules Peptides Biomarkers Studies Stem Cells Editorial Methodology
Layer 1 · Decision
← All products
DoNotAge

Pure Resveratrol

Sirtuin activator · Powder · 30 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Active per serving
Resveratrol 1,000 mg
Form
Powder
List price (catalog, USD)
$40.00
Price per serving
$1.33List price divided by servings per container. A per-day cost only if the label serving is once daily.
Full label record: servings, testing, ingredients
Servings per container
30
Serving size (label)
1 g
Catalog monthly estimate
$40.00
Testing disclosure
Brand lists third-party testing and a public certificate of analysis (CoA)Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

IngredientAmount per serving
Resveratrol1,000 mg

What to check on the label

  • Whether the label says trans-resveratrol with a purity percentage, or only 'resveratrol' or 'Japanese knotweed extract'.
  • Whether the milligrams refer to the compound or to the extract it comes from.
  • Powders list a scoop size. Check that it matches the serving in the catalog.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

5.8/10
Overall score
#7 / 17 in Sirtuin activator

Public lab certificate, tested by independent lab, top 12% value.

Read the evidence (3 studies)
Add to compareVisit brand site →
Tier 3
Ingredient RCT (matching dose)
The ingredient was tested in an RCT at the same dose this product sells.
See the 3 supporting studies
How we scored this product Show the full breakdown
Dose vs. studies (50%) Why 4.9 of 10. Primary ingredient is Resveratrol (evidence grade C). It delivers 1000 mg, inside the studied range of 150–1000 mg. Read the rule → 4.9
Transparency (20%) Why 9.5 of 10. Earned points for public certificate of analysis and independent third-party testing and all doses disclosed. Read the rule → 9.5
Value (10%) Why 9.2 of 10. One day at the trial dose costs about $0.67. That is cheaper than average (88 of 313 by cost per effective day). Read the rule → 9.2
Formulation (10%) Why 5.0 of 10. No published absorption advantage or disadvantage on file. The default of 5 is not a criticism. Read the rule → 5.0 Default. No absorption data on file.
Safety (5%) Why 8.5 of 10. Baseline 5.0. Third-party testing adds 2.0. Public lab certificate adds 1.5. NSF, USP or Informed Choice certification adds 1.5. Active safety signal subtracts 3.0. Read the rule → 8.5
Community sentiment (5%) Why 8.9 of 10. Sentiment across 4 external review source(s) is mostly positive. Community is a signal about daily use, not proof of effect. Read the rule → 8.9
Composite How this 5.8 is built. 0.50 × 4.9 + 0.20 × 9.5 + 0.10 × 9.2 + 0.10 × 5.0 + 0.05 × 8.5 + 0.05 × 8.9 = 5.8 out of 10. Safety caps applied after. 5.8
5.8 composite
Dose vs. studies50%4.9
Transparency20%9.5
Value10%9.2
Formulation10%5.0
Safety5%8.5
Community5%8.9

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Editorial verdict

Quick verdict

5.8 / 10
Best for
Full trial dose, Public lab certificate
Avoid if
No major red flags
Full-dose status
Meets trial dose
Price/month
$40
COA status
Public
Biggest caveat
Dose-evidence score of 4.9 is below average for the site.
Nearest alternatives
Catalog snapshot. Check linked sources for current price, label and batch-specific testing.
Price verification
Current price: $40.00
Last price check: Sep 01, 2026
Add to compareVisit brand site →
Layer 2 · Context

Our summary

Pure Resveratrol is a straightforward ≥98%-purity trans-resveratrol capsule/powder, recommended at 1000 mg/day and priced around $1.80/day at that dose. Resveratrol's SIRT1-activation mechanism has reasonable meta-analytic backing, and one dose-comparison RCT in older diabetics specifically supports 1000 mg/day over 500 mg/day on oxidative-stress markers — a rare case where a vendor's recommended dose lines up closely with what a controlled trial actually tested. That said, resveratrol research overall remains fragmented across doses and populations, individual liver-health claims are uncited, and none of the underlying studies used DoNotAge's specific product.
In plain language

Why this scored this way

This DoNotAge Pure Resveratrol scores 6.6, making it a mid-tier product with both strengths and weaknesses. It delivers 1000mg of Resveratrol, inside the studied range of 150–1000mg with grade C evidence (mostly preclinical, limited human data). Transparency is a clear strength (score: 9.5), with third-party testing and a public lab certificate.

What drives the score up

  • Quality transparency of 9.5: tested by independent lab with a public lab certificate.
  • Community score of 8.9 with positive consumer feedback.

What drags it down

  • Dose-evidence score of 4.9 is below average for the site.
  • Resveratrol (1000mg is 200% of the 500mg trial dose) is well above the trial dose. More is not always better.

Why you'd choose it

  • You want good value at $0.67/day.
  • You prioritise tested by independent lab products with public lab certificates.

Why you might skip it

  • You want a standard dose of resveratrol (this product is well above it).
Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Resveratrol

The famous red-wine molecule; longevity claims have outrun the human evidence.

3 landmark RCTs · US: Dietary supplement · EU: Authorised Novel Food (2016/1866)
Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
100% of trial dose
Meets or exceeds the published effective dose
Cost at trial dose
$0.67/day at trial dose
What one effective daily dose actually costs
Transparency
9.5/10 · Public lab certificate (quality: not assessed)
Independent batch testing confirmed
Consumer signals
No consumer signals collected yet
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

!
Review advised
resveratrol: CYP3A4 interactions
Safety signals
Drug interaction risk — resveratrol
Resveratrol inhibits CYP3A4, CYP2C9, and CYP2D6 at doses ≥1,000 mg/day. Potential interactions with warfarin, statins, and NSAIDs.
Read more
Safety flag
resveratrol: CYP3A4 interactions
Dose or interaction risk detected. See ingredient page for details.
Plain English

What’s inside

The main ingredients of this product, in plain language.

Resveratrol1000 mgEvidence C

The famous red-wine molecule; longevity claims have outrun the human evidence.

Read about Resveratrol →
Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price
$40
per bottle · 30 servings
Dose vs. research
of trial dose 100%
of published effective dose
$ / day at studied dose
$0.67
what one effective daily dose costs
$ / g active
$1.33
per gram of active substance
Independently checked

Data verification

COA status
Public
Evidence grade
C
Per-ingredient breakdown
CResveratrol

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Evidence
Resveratrol
The famous red-wine molecule; longevity claims have outrun the human evidence.
Timmers et al. 2011 (Cell Metabolism)RESHAW 2020Lozupone 2026 (Expert Opin Investig Drugs)
1000 mg 200% of trial dose
500 mg
4.4 /5
High confidence Strong value signal
3,217 reviews across 3 platforms (10 sources)
Source diversity: 85%
Examine.comTrustpilotWalmart
PraiseBrand-level rating 4.6/5. Users like the ≥98% trans-resveratrol purity claim.
Last checked: 2026-08-20

Consumer signals

Consumer signals gathered from 10 platforms.

Medium confidence

Consumer sentiment compiled from 2 public sources (Examine.com, Trustpilot).

Examine.com

mixed sentiment

Themes

Examine notes resveratrol's bioavailability is poor and clinical benefit inconsistent, irrespective of brand.

Compiled from an Examine.com listing located during manual research; not independently re-verified against the live page at build time.

Trustpilot

556 reviews · 4.6/5 · positive sentiment

Praise

Brand-level rating 4.6/5. Users like the ≥98% trans-resveratrol purity claim.

Compiled from a Trustpilot listing located during manual research; not independently re-verified against the live page at build time.

Walmart

29 reviews · 4.9/5

Walmart

29 reviews

Walmart

7 reviews

Same brand profile on Trustpilot country sites: UK 4.4 · Germany 4.4 · Switzerland 4.4 · Italy 4.3 · Spain 4.5.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say, with a source hierarchy

We treat external opinion very differently depending on where it comes from. Tier A is our strongest signal. Tier C is background sentiment only. Tier Rejected is what we excluded, listed openly so you can see what we discarded.

These reviews are aggregated from third-party sources, not written by NO1GEVITY. Each entry shows its source, retrieval date, and whether the source has an affiliate or paid relationship. We do not edit reviews to change their meaning. Disclosure policy.

Tier B

Registered dietitians and physicians, without affiliate ties

Credentialed commentary from clinicians who disclose no paid relationship. Useful as supporting critique but not a substitute for a clinical outcome trial.

Physician YouTube analysis — DoNotAge Longevity Sachet
Has affiliate relationship Not a paid placement

Detailed ingredient walk-through. Discount code and buy link present, so the editorial score is discarded; ingredient/dose facts extracted.

How we use it: Ingredient/dose facts only. Editorial rating rejected.
Tier C

Aggregated sentiment (Trustpilot, Reddit)

Mood indicator only. We never use aggregate stars as evidence of efficacy.

Trustpilot — DoNotAge (aggregated sentiment)
No affiliate relationship Not a paid placement

Aggregate score ≈ 4.3-4.5 / 5. Mood indicator only.

Finding: 4.3-4.5 / 5.
How we use it: Sentiment only. Never used as evidence of efficacy.

Community threads and aggregate ratings

Additional public mentions we located, kept separate from the deep independent reviews above.

Examine.com
mixed

Examine notes resveratrol's bioavailability is poor and clinical benefit inconsistent, irrespective of brand.

Read source → Unverified · we received no payment for this listing
Trustpilot · 4.6
positive

Brand-level rating 4.6/5. Users like the ≥98% trans-resveratrol purity claim.

Read source → Unverified · we received no payment for this listing
Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence, what actually backs this product

Longevity brands rarely test their exact finished product. We separate what's tested from what's inferred.

Strongest evidence tier
Tier 3Ingredient RCT (matching dose)
4 studies mapped
Tier 3Ingredient RCT (matching dose)
Effect of resveratrol supplementation on oxidative stress markers and SIRT1 in older adults with type 2 diabetes
Various (dose-comparison RCT authors) · 2023 · peer-reviewed clinical nutrition journal (dose-comparison RCT) · n=97 · 1000 mg/day and 500 mg/day, compared head-to-head · 6 months
ingredient-levelpeer-reviewed
This head-to-head dose comparison found the 1000 mg/day group showed a statistically significant improvement in oxidative stress markers and SIRT1 levels compared with both the 500 mg/day group and placebo, directly supporting DoNotAge's higher recommended dose over its lower one.
This is one of the more directly relevant studies in the registry, since it specifically tests DoNotAge's exact 1000 mg/day recommended dose against a lower dose in a controlled design, though the population (older diabetics) may not generalize to a healthy adult consumer.
Conflicts: Academic study; no disclosed link to DoNotAge.
Source →
Tier 3Ingredient RCT (matching dose)
Systematic review and meta-analysis of resveratrol's effect on SIRT1 gene/protein expression
Various (systematic review authors) · 2025 · peer-reviewed meta-analysis (indexed via PubMed) · Ranges across pooled trials, several at or near 1000 mg/day · Varies by pooled trial
ingredient-levelpeer-reviewed
Pooling 11 RCTs, this meta-analysis found a statistically significant overall increase in SIRT1 gene and protein expression with resveratrol supplementation, lending some support to the sirtuin-activation mechanism marketed on the product page.
Confirms the SIRT1-activation claim has reasonable meta-analytic support at the gene/protein-expression level, though this is a biomarker outcome, not direct evidence of a clinical anti-aging benefit in healthy people.
Conflicts: Academic meta-analysis; no disclosed link to DoNotAge.
Source →
Tier 3Ingredient RCT (matching dose)
Systematic review of resveratrol's effect on sirtuin gene expression across randomized controlled trials
Various (systematic review authors) · 2021 · peer-reviewed systematic review · Varies by pooled trial · Varies by pooled trial
ingredient-levelpeer-reviewed
Reviewing 7 RCTs, this earlier systematic review found 4 of 7 trials showed a significant increase in SIRT1 with resveratrol, a more mixed picture than the larger 2025 meta-analysis, underscoring inconsistency across smaller individual trials.
Included to show that not all systematic reviews agree, and that resveratrol's SIRT1 effect, while plausible, is not uniformly replicated across every individual trial.
Conflicts: Academic systematic review.
Source →
Tier 4Ingredient RCT (different dose)
Systematic review of clinical trials using defined-dose purified resveratrol across multiple conditions
Various (systematic review authors) · 2024 · peer-reviewed systematic review (PMC-indexed) · Highly variable, 5 mg to 5000 mg/day across pooled trials · Variable
ingredient-levelpeer-reviewed
This broad review of purified-resveratrol trials found no consensus treatment regimen across conditions and highlighted substantial knowledge gaps, suggesting the field has not converged on an optimal dose or population for resveratrol's benefits.
Useful context showing resveratrol research overall remains fragmented; it tempers overly confident claims either for or against any single dose, including DoNotAge's 1000 mg recommendation.
Conflicts: Academic review.
Source →
Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

ResveratrolTimmers et al. 2011 (Cell Metabolism)
ResveratrolRESHAW 2020
ResveratrolLozupone 2026 (Expert Opin Investig Drugs)

Claim check, vendor claims vs. our reading of the evidence

Not medical advice. We list the strongest claims made by the brand and check each against traceable evidence.

Partial support
“Pure Resveratrol activates Sirtuin 1 in the body”
A 2025 meta-analysis of 11 RCTs found a statistically significant overall increase in SIRT1 expression with resveratrol supplementation, but an earlier 2021 review of 7 RCTs found only 4 of 7 trials showed a significant effect, indicating the finding is directionally supported but not perfectly consistent across all individual studies.
Vendor source
No evidence
“Improves liver health”
No specific liver-health trial is cited on the product page, and the studies located in our research focused on oxidative stress, SIRT1 expression, and diabetes markers rather than liver function endpoints specifically.
Vendor source
Supported
“1000 mg/day recommended dose supports heart health and protects cells from oxidative stress”
A direct head-to-head dose-comparison RCT in older diabetic adults found 1000 mg/day outperformed 500 mg/day on oxidative stress markers over six months, giving reasonable support to DoNotAge's specific recommended dose, though this was studied in a diabetic population rather than healthy consumers generally.
Vendor source

Regulatory status

Rules change often. We record when we last verified each row. See the full regulatory timeline →

US
Legal as supplement
Resveratrol is a long-established dietary supplement ingredient in the US with no equivalent to NMN's drug-preclusion dispute.
Last verified 2026-08-05
EU
Legal as supplement
Trans-resveratrol has an established history of use as a food supplement ingredient across EU member states and is not subject to the same Novel Food uncertainty as NMN.
Last verified 2026-08-05
UK
Legal
Sold as a standard food supplement ingredient in the UK.
Last verified 2026-08-05
CA
Legal as supplement
Resveratrol products are commonly licensed as Natural Health Products in Canada; specific DoNotAge NPN status was not confirmed.
Last verified 2026-08-05

What we could not verify

We list this openly. If a claim isn't backed by a source we can trace, we'd rather flag it than repeat it.

  • Whether DoNotAge's specific resveratrol extract (as opposed to generic ≥98% trans-resveratrol from other suppliers) has appeared in any published clinical trial was not confirmed.
  • The liver-health claim on the product page could not be traced to a specific supporting study.
Important to know
Resveratrol"Resveratrol" products that don't specify trans-isomer content are unmeasurable in practice. Cis-resveratrol is biologically inactive.

Editorial notes

≥98% trans-resveratrol per third-party CoA.

Go deeper

Where this sits

Actives inside
Resveratrol
Category
See all in Sirtuin activator →
Brand
DoNotAge profile →
Add to compare Visit brand site →
Brand owners

Spot an error?

If you are the manufacturer or brand owner of Pure Resveratrol and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
Same shelf

Similar products

All Sirtuin activator →

The next highest-scoring products in Sirtuin activator, same scoring method, same rules.

Sirtuin activator
Active per serving
Quercetin 500 mgTablet · 120 servings
Price per serving
$0.15$17.99 · 120 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 7.8/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.15
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with nootropicsdepot.com
DoNotAge
Pure Quercetin
Sirtuin activator
Active per serving
Quercetin 400 mgCapsule · 366 servings
Price per serving
$0.10$35.00 · 366 servings
Testing
3rd-party listed · no public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 7.3/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.12
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with donotage.org
BulkSupplements
Quercetin Dihydrate Powder
Sirtuin activator
Active per serving
Quercetin 1,000 mgPowder · 100 servings
Price per serving
$0.27$26.97 · 100 servings
Testing
None listed

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.9/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.13
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.bulksupplements.com
Same maker

Other products from DoNotAge

Brand profile →
Mitochondrial
Active per serving
Creatine 10 gPowder · 30 servings
Price per serving
$0.88$26.50 · 30 servings
Testing
3rd-party listed · no public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 8.6/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.44
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with donotage.org
DoNotAge
Pure Berberine
Metabolic
Active per serving
Berberine 1,500 mgPowder · 30 servings
Price per serving
$1.00$30.00 · 30 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 8.3/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$1.00
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with donotage.org
Vitamin
Vitamin per serving
Magnesium 250 mgElemental vs compound: check label
Price per serving
$0.07$24.00 · 366 servings
Testing
None listed

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 8.2/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.08
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with donotage.org
DoNotAge
Pure NR
NAD+ booster
Precursor per serving
NR 500 mgPowder · 30 servings
Price per serving
$1.83$55.00 · 30 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 8.1/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$1.10
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with donotage.org
DoNotAge
Pure NMN
NAD+ booster
Precursor per serving
NMN 1,000 mgPowder · 30 servings
Price per serving
$2.17$65.00 · 30 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 8.1/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

400%
of trial dose
$1.08
per research-dose day, not label serving
400% · over 2× trial dose0Trial dose2×
Catalog price · Confirm current price with donotage.org