The famous red-wine molecule; longevity claims have outrun the human evidence.
Overhyped but not useless. If you take it, choose products that use trans-resveratrol (not blends) and pair with a fatty meal for absorption.
Resveratrol (trans-Resveratrol) is a polyphenol / sirtuin activator with evidence grade C, meaning it is backed by mixed or small human trials. We track 33 products containing Resveratrol. Typical doses range from 12.5 to 1000 mg per serving. The top-ranked product scores 7.1 out of 10 on our composite scale (dose, evidence, price, testing, transparency). Prices range up to $617.83 per month.
| Product | Brand | Dose | Price/mo | 3rd-party tested | Score |
|---|---|---|---|---|---|
| NAD+ 1500 (Liposomal NAD+ with RiaGev-WS and Resveratrol) | Toniiq | 100 mg | $27.97 | Yes | 7.1 |
| Bulk Micronized Trans-Resveratrol Powder - 1 kilo | ProHealth Longevity | 1000 mg | $617.83 | Yes | 7.0 |
| ResveraCel | Thorne HealthTech | 150 mg | $105.00 | Yes | 7.0 |
| Youngr NMN | Wonderfeel | 100 mg | $88.00 | Yes | 7.0 |
| Daily Longevity Blend | AgeMate | 50 mg | $69.00 | Yes | 7.0 |
Scores are editorial judgments, not a scientific standard. See how we score.
A compound made by plants under stress (grape skins, Japanese knotweed). In lab animals fed high doses, it mimics some of the effects of eating less food, a well-established longevity intervention.
Mouse and yeast studies are impressive. Human studies are mixed: some show improvements in insulin sensitivity or blood-vessel function, others show nothing. Absorption is poor, most of what you swallow gets broken down before it reaches your cells.
Overhyped but not useless. If you take it, choose products that use trans-resveratrol (not blends) and pair with a fatty meal for absorption.
3,5,4'-trihydroxy-trans-stilbene. SIRT1 activator (contested), AMPK modulator, phytoalexin.
Yeast and murine models show lifespan extension in high-fat contexts. Human trials mixed; RESHAW (2020) failed to replicate cognitive benefits. Bioavailability <1% oral; extensive first-pass sulfation/glucuronidation.
~2 hours; metabolites persist longer.
"Resveratrol" products that don't specify trans-isomer content are unmeasurable in practice. Cis-resveratrol is biologically inactive.
When a product exceeds the UL or contains an ingredient with clinically significant interactions, a "Review advised" flag appears on its product page and links here.
Source: https://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/resveratrol
The trial dose above is our editorial pick from the published human trials for this ingredient. We choose the dose that the best-available studies used on the endpoint most relevant to longevity. The range shows the lowest and highest doses tested in published trials. The landmark studies below are the papers we read to set it. You can click through and check our work.
When new trials publish, our automated sweeps flag them. If a new study materially changes the dose, we update it through editorial review and record the old dose, new dose, and the triggering study in every affected product's recommendation history. The dose is never changed automatically.
Regulatory events, evidence grade changes, and key research milestones for Resveratrol, most recent first. Studies link to the paper; regulatory entries name and link the responsible authority.
Consumer reports submitted to an official government adverse-event database. These reports mention this ingredient but do not prove it caused the reaction. Report volume reflects market penetration as much as inherent risk.
Retrieved from the FDA Adverse Event Reporting System (CAERS) via the openFDA API. Verified 2026-08-06. Reports are voluntary consumer submissions and mandatory serious-event filings. They establish surveillance, not causality.
150 mg/day for 30 days improved metabolic profile in obese men.
Read study →12 months of 150 mg twice daily in postmenopausal women showed no cognitive benefit.
Read study →26-year critical review of longevity pharmacology. Despite rapid mechanistic advances in senolytics, autophagy modulators, and metabolic pathway targets, clinical translation remains uncertain.
Read study →All products in our catalog that contain Resveratrol, ranked by our overall score. Ranking is editorial, never paid.
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
ProHealth LongevityStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Thorne HealthTechMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
WonderfeelMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
AgeMateMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
ProHealth LongevityUndisclosed amounts noted
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
ProHealth LongevityMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
ToniiqStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Thorne HealthTechMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
OmreStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
CodeageMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
DoNotAgeStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
AOR (Advanced Orthomolecular Research)Multi-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Double Wood SupplementsStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Multi-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
CodeageMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
MitoQMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
LemmeMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Life ExtensionMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Life ExtensionStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
ID FormulasEPA/DHA split not stored
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Renue By ScienceStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
ToniiqStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
RevgeneticsStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Perpetua LifeMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
INSTYTUTUMStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Life ExtensionMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Jarrow FormulasMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
INSTYTUTUMDaily use may exceed one serving
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Doctor's BestMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
SupersmartMulti-ingredient bundle
Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.
Molecules in the same class, plus the actives most often formulated alongside Resveratrol in our catalogue.
See Resveratrol in context: the mechanism it acts through, the biomarker it moves, the products that dose it, and the trials that tested it.
View Resveratrol on the Longevity Map →A compound made by plants under stress (grape skins, Japanese knotweed). In lab animals fed high doses, it mimics some of the effects of eating less food, a well-established longevity intervention.
The trial dose in published human studies is 500 mg per day, with a range of 150 to 1000 mg per day. Always consult a qualified clinician before starting any supplement.
No formal UL/RDA established. Well tolerated up to ~1,000 mg/day; gastrointestinal effects (nausea, diarrhea) become common above 1,000-2,500 mg/day.
We track 33 products containing Resveratrol. The top-ranked product scores 7.1 out of 10 on our composite scale, which evaluates dose, evidence, price, third-party testing, and transparency. See the comparison table above. Scores are editorial judgments, not a scientific standard.
Resveratrol has evidence grade C, meaning it is backed by mixed or small human trials. Grade A means replicated human RCTs with hard endpoints. Grade B means human RCTs with biomarker outcomes. Grade C means mixed or small human trials. See our evidence grading methodology.
Evidence grades are reviewed when new human RCTs are published. Product counts update automatically as new products are added. Dose ranges reflect published trial data, not brand recommendations. Read how we verify.
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