What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.
Ingredients listed
7 ingredients listed largest listed: NMN 250 mg
Form
Capsule
List price (catalog, USD)
$59.00
Price per serving
$1.97List price divided by servings per container. A per-day cost only if the label serving is once daily.
Reading notes
Multi-ingredient product. Amounts are per ingredient per serving; the product is assessed as one bundle, not as a recommendation for each ingredient.
Full label record: servings, testing, ingredients
Servings per container
30
Serving size (label)
1 g
Catalog monthly estimate
$59.00
Testing disclosure
Brand lists third-party testing; no public lab certificate listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.
Whether every ingredient has its own milligram line, or several are grouped in a 'blend' with one total.
How many capsules or scoops make a serving, and how many servings the container holds.
Whether the ingredients you care about appear at amounts you would accept on their own. The list below shows each figure.
Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.
Editorial score and research-dose calculations
These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.
Watch outEU restricted2 ingredients restricted in the EU
NMN — Unauthorised Novel Food; EFSA positive safety opinion adopted 4 March 2026 at up to 300 mg/day (β-NMN, EffePharm dossier). Commission listing pending.
Spermidine — Novel Food status for concentrates >7 mg; wheat-germ traditional food
You can legally buy these outside the EU. Sale as a food supplement inside the EU requires a Novel Food authorisation these ingredients do not have.
Tier 3
Ingredient RCT (matching dose)
The ingredient was tested in an RCT at the same dose this product sells.
See the 3 supporting studies▾
Okabe et al. 2022 (Frontiers in Nutrition)(NMN)A 30-person, 12-week RCT found 250 mg/day oral NMN significantly increased whole-blood NAD+ levels with no adverse effects. Studied at 250 mg. This product: 250 mg.
Uthever RCT 2022(NMN)In 66 adults aged 40-65 over 60 days, NMN (300 mg/day) increased serum NAD+/NADH by 38% versus baseline and improved SF-36 quality-of-life scores compared to placebo. Studied at 300 mg. This product: 250 mg.
Yi et al. 2023 (GeroScience)(NMN)In an 80-person, 60-day dose-dependent RCT, oral NMN (up to 900 mg/day) significantly raised blood NAD+ levels, was safe and well-tolerated, and improved six-minute walking distance versus placebo. Studied at 900 mg. This product: 250 mg.
How we scored this productShow the full breakdown▾
Dose vs. studies (50%)iWhy 5.3 of 10. Primary ingredient is NMN (evidence grade B). It delivers 250 mg, inside the studied range of 250–900 mg. Read the rule →5.3
Transparency (20%)iWhy 6.5 of 10. Earned points for independent third-party testing and all doses disclosed. Lost points for no public certificate of analysis. Read the rule →6.5
Value (10%)iWhy 4.5 of 10. One day at the trial dose costs about $3.93. That is one of the pricier options in the catalog (266 of 313 by cost per effective day). Read the rule →4.5
Formulation (10%)iWhy 5.0 of 10. No published absorption advantage or disadvantage on file. The default of 5 is not a criticism. Read the rule →5.0
Default. No absorption data on file.
Safety (5%)iWhy 7.0 of 10. Baseline 5.0. Third-party testing adds 2.0. Public lab certificate adds 1.5. NSF, USP or Informed Choice certification adds 1.5. Active safety signal subtracts 3.0. Read the rule →7.0
Community sentiment (5%)iWhy 7.9 of 10. No external reviews found, so community sentiment defaults to neutral. Community never counts as clinical evidence. Read the rule →7.9
CompositeiHow this 4.9 is built. 0.50 × 5.3 + 0.20 × 6.5 + 0.10 × 4.5 + 0.10 × 5.0 + 0.05 × 7.0 + 0.05 × 7.9 = 4.9 out of 10. Safety caps applied after.4.9
4.9composite
Dose vs. studies50%5.3
Transparency20%6.5
Value10%4.5
Formulation10%5.0
Safety5%7.0
Community5%7.9
Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.
This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.
This Perpetua Life AEON with Nicotinamide DUO scores 5.7, making it below the site average. It delivers 250mg of NMN, inside the studied range of 250–900mg with grade B evidence (promising human data, not yet comprehensive). At $3.93/day it's among the more expensive options in Longevity stack.
What drives the score up
NMN is dosed at the full research level with grade B evidence (promising human data, not yet comprehensive).
What drags it down
Dose-evidence score of 5.3 is below average for the site.
Resveratrol (100mg is 20% of the 500mg trial dose) is significantly under-dosed.
Quercetin (50mg is 10% of the 500mg trial dose) is significantly under-dosed.
Fisetin (50mg is 10% of the 500mg trial dose) is significantly under-dosed.
Spermidine (5mg is 417% of the 1.2mg trial dose) is well above the trial dose. More is not always better.
Why you'd choose it
You want NMN from a Perpetua Life product.
You want a tested by independent lab product.
Why you might skip it
You want a product with a publicly available CoA.
You need a full trial dose of resveratrol (this product under-doses it).
You want a standard dose of spermidine (this product is well above it).
Question 1
Does the molecule work?
The science behind each active ingredient, independent of which brand sells it.
A NAD+ building block that has become the most-hyped longevity molecule.
5 landmark RCTs · US: FDA reversed exclusion 29 September 2025; NDIN 1247 and NDIN 1259 reinstated 2 December 2025; NDIN 1444 (β-NMN, Effepharm) response 28 January 2026. NMN is a dietary ingredient again; each marketer still needs NDIN coverage. · EU: Unauthorised Novel Food; EFSA positive safety opinion adopted 4 March 2026 at up to 300 mg/day (β-NMN, EffePharm dossier). Commission listing pending.
Every active in this formula, its declared dose per serving, the dose used in the primary human trial, how much of that trial dose this product delivers, and the evidence grade for the ingredient itself.
Percentages are dose per serving ÷ primary trial dose. Below 50% means the formula is unlikely to reproduce the trial outcome for that active. Grade A = multiple large human RCTs. Grade F = no human evidence. How grades work. Full glossary →
Question 2
Is this bottle good?
The specific product: dose, price, transparency, and what buyers report.
Dose vs research
100% of trial dose
Meets or exceeds the published effective dose
Cost at trial dose
$3.93/day at trial dose
What one effective daily dose actually costs
Transparency
6.5/10 · No public lab certificate
Independent batch testing confirmed
Consumer signals
304 reviews across platforms · 3.7/5 · high confidence
Operational signal only, never used as clinical evidence
Question 3
What's the catch?
Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.
Hard numbers and independently checked status. Expand each block for its source.
The numbers
Price
$59
per bottle · 30 servings
Dose vs. research
of trial dose 100%
of published effective dose
$ / day at studied dose
$3.93
what one effective daily dose costs
$ / g active
$3.54
per gram of active substance
Independently checked
Data verification
COA status
Not public
Evidence grade
BCBCCCB
Per-ingredient breakdown
BNMN
CResveratrol
BQuercetin
CFisetin
CBetaine (TMG)
CSpermidine
BL-Theanine
All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.
NMNAbsorption varies wildly by form. Sublingual and liposomal claim better uptake but human head-to-head data is limited.
Resveratrol"Resveratrol" products that don't specify trans-isomer content are unmeasurable in practice. Cis-resveratrol is biologically inactive.
QuercetinPlain quercetin dihydrate has poor absorption. Phytosome forms deliver 10 to 20× more into blood.
FisetinStandard capsules have <5% absorption. Look for liposomal or with piperine.
Betaine (TMG)Doses under roughly 500 mg/day (as seen in most NAD+ combination products) are well below the gram-level doses used in the supporting human trials.
SpermidineProduct labels often say 'wheat germ extract 800 mg', that could be 0.8 mg or 8 mg of actual spermidine. Insist on labeled spermidine content.
L-TheanineVery safe. Suntheanine® is the branded form with the most published data.
Editorial notes
Liposomal 11-ingredient longevity complex combining NMN/NR with resveratrol, quercetin, fisetin, spermidine and astragalus; tested yearly by Twin Arbor Labs (ISO 17025).
If you are the manufacturer or brand owner of AEON with Nicotinamide DUO and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.
We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.
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