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Category · 17 products

Sirtuin activator

Polyphenols proposed to act on the sirtuin family. Strong mechanistic story, mixed human data.

Category statistics and scoring
17
5.6
A
T1
15
$0.12
Compare the top 3 → Filter the full index →
Ranked

Every Sirtuin activator product we score

Same formula as the rest of the site. Position here has never been bought.

Reading guide

How to read this shelf

Resveratrol, pterostilbene and quercetin products. Purity grades ('trans-resveratrol 98%') and micronised or liposomal wording appear on labels. The catalog stores the milligram figure given for the compound.

Check on every label

  • Whether the label says trans-resveratrol with a purity percentage, or only 'resveratrol' or 'Japanese knotweed extract'.
  • Whether the milligrams refer to the compound or to the extract it comes from.
  • Powders list a scoop size. Check that it matches the serving in the catalog.
Catalog figures for this shelf (17)
Products
17
Most common lead ingredients
Resveratrol (11), Quercetin (3), Pterostilbene (2)
Forms
Capsule (11), Powder (4), Tablet (2)
Range of Resveratrol per serving
125 mg to 1,000 mg across 11 products
Price per serving
$0.10 to $2.00
Testing listed
13 of 17 list third-party testing · 8 publish a CoA
Multi-ingredient products
2 of 17 list three or more ingredients

Counts and ranges are catalog facts about the labels, not a ranking. The score, evidence and safety sections below are separate.

Top 3 for this shelf

The three best-evidenced options here, with the plain verdict and the catch first. The full ranking continues below.

01
Nootropics Depot
Quercetin Tablets | 95% Anhydrous
Sirtuin activator
Active per serving
Quercetin 500 mgTablet · 120 servings
Price per serving
$0.15$17.99 · 120 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 7.8/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.15
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with nootropicsdepot.com

Verdict: This Nootropics Depot Quercetin Tablets | 95% Anhydrous scores 7.8, making it a strong scorer. It delivers 500mg of Quercetin, inside the studied range of 250–1000mg with grade B evidence (promising human data, not yet comprehensive). Transparency is a clear strength (score: 9.0), with third-party testing and a public lab certificate. At $0.15/day it's priced well for what you get.

02
DoNotAge
Pure Quercetin
Sirtuin activator
Active per serving
Quercetin 400 mgCapsule · 366 servings
Price per serving
$0.10$35.00 · 366 servings
Testing
3rd-party listed · no public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 7.3/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.12
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with donotage.org

Verdict: This DoNotAge Pure Quercetin scores 7.3, making it a mid-tier product with both strengths and weaknesses. It delivers 400mg of Quercetin, inside the studied range of 250–1000mg with grade B evidence (promising human data, not yet comprehensive). At $0.12/day it's priced well for what you get.

The catch: No public lab certificate available for independent verification.

03
BulkSupplements
Quercetin Dihydrate Powder
Sirtuin activator
Active per serving
Quercetin 1,000 mgPowder · 100 servings
Price per serving
$0.27$26.97 · 100 servings
Testing
None listed

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.9/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.13
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.bulksupplements.com

Verdict: This BulkSupplements Quercetin Dihydrate Powder scores 6.9, making it a mid-tier product with both strengths and weaknesses. It delivers 1000mg of Quercetin, inside the studied range of 250–1000mg with grade B evidence (promising human data, not yet comprehensive). The quality transparency (6.0) is limited by the lack of third-party testing. At $0.13/day it's priced well for what you get.

The catch: Quercetin (1000.0mg is 200% of the 500mg trial dose) is well above the trial dose. More is not always better.

Quick compare

Top 5 in Sirtuin activator

Sorted by overall score. Same numbers you'll see on each product page.

#ProductScorePrimary activeDose vs RCTPrice/moValue rankDose+Evidence
#1Quercetin Tablets | 95% Anhydrous
Nootropics Depot
7.8/10Quercetin 500mg✅ 100%$18/moTop 9%7.2/10
#2Pure Quercetin
DoNotAge
7.3/10Quercetin 400mg✅ 100%$3/moTop 1%7.2/10
#3Quercetin Dihydrate Powder
BulkSupplements
6.9/10Quercetin 1000mg✅ 100%$8/moTop 9%7.2/10
#4Bulk Micronized Trans-Resveratrol Powder - 1 kilo
ProHealth Longevity
6.2/10Resveratrol 1000mg✅ 100%$618/moMid-range5.9/10
#5Trans-Resveratrol Plus - 1000 mg per serving
ProHealth Longevity
6.1/10Resveratrol 1000mg✅ 100%$31/moMid-range6.2/10
Show all 17 Sirtuin activator products →
Sirtuin activator
Active per serving
Resveratrol 1,000 mgPowder · 500 servings
Price per serving
$1.24$617.83 · 500 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.2/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.62
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.prohealth.com
Sirtuin activator
Active per serving
Resveratrol 1,000 mg+ Quercetin 420 mg
Price per serving
$1.04$31.08 · 30 servings
Testing
3rd-party listed · public lab certificate

Undisclosed amounts noted

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.1/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.52
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.prohealth.com
06
Double Wood Supplements
Pterostilbene Supplement
Sirtuin activator
Active per serving
Pterostilbene 100 mgCapsule · 60 servings
Price per serving
$0.33$19.95 · 60 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 5.9/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.33
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with doublewoodsupplements.com
07
DoNotAge
Pure Resveratrol
Sirtuin activator
Active per serving
Resveratrol 1,000 mgPowder · 30 servings
Price per serving
$1.33$40.00 · 30 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 5.8/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.67
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with donotage.org
Sirtuin activator
Active per serving
Resveratrol 1,000 mgCapsule · 90 servings
Price per serving
$0.94$84.99 · 90 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 5.8/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.47
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with nootropicsdepot.com
09
Double Wood Supplements
Resveratrol Supplement (Trans-Resveratrol)
Sirtuin activator
Active per serving
Resveratrol 500 mgCapsule · 60 servings
Price per serving
$0.33$19.95 · 60 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 5.7/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.33
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with doublewoodsupplements.com
10
Renue By Science
Trans-Resveratrol (Liposomal)
Sirtuin activator
Active per serving
Resveratrol 125 mgCapsule · 90 servings
Price per serving
$0.47$41.95 · 90 servings
Testing
3rd-party listed · no public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 5.3/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

83%
of trial dose
$1.86
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with renuebyscience.com
11
Toniiq
Resveratrol 98%
Sirtuin activator
Active per serving
Resveratrol 300 mgCapsule · 30 servings
Price per serving
$0.73$21.97 · 30 servings
Testing
3rd-party listed · no public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 5.1/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$1.22
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.toniiq.com
Sirtuin activator
Active per serving
Resveratrol 500 mgCapsule · 30 servings
Price per serving
$1.33$39.95 · 30 servings
Testing
3rd-party listed · no public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 4.9/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$1.33
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.revgenetics.com
Sirtuin activator
Ingredients listed
4 ingredients listedlargest listed: Resveratrol 200 mg
Price per serving
$0.47$28.21 · 60 servings
Testing
None listed

Multi-ingredient bundle

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 4.8/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$1.18
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with acuatlanta.net
Sirtuin activator
Active per serving
Resveratrol 1,000 mgPowder · 10 servings
Price per serving
$2.00$19.97 · 10 servings
Testing
None listed

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 4.8/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$1.00
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.bulksupplements.com
15
Life Extension
Optimized Resveratrol Elite
Sirtuin activator
Ingredients listed
3 ingredients listedlargest listed: Resveratrol 250 mg
Price per serving
$1.33$40.00 · 30 servings
Testing
3rd-party listed · public lab certificate

Multi-ingredient bundle

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 4.8/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$2.67
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.lifeextension.com
Sirtuin activator
Active per serving
Pterostilbene 50 mgCapsule · 60 servings
Price per serving
$0.60$35.99 · 60 servings
Testing
None listed

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 4.7/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$1.20
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with jarrow.com
17
DoNotAge
SIRT6Activator®
Sirtuin activator
Active per serving
SIRT6 Activator 400 mgCapsule · 366 servings
Price per serving
$0.27$97.00 · 366 servings
Testing
3rd-party listed · no public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 3.8/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

40%
of trial dose
$2.65
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with donotage.org
Connected

What defines this shelf

Actives used here
Resveratrol (11)Quercetin (6)Pterostilbene (3)Vitamin C (1)EGCG (1)SIRT6 Activator (1)
Brands competing
DoNotAge (3)Nootropics Depot (2)BulkSupplements (2)ProHealth Longevity (2)Double Wood Supplements (2)Jarrow Formulas (2)Renue By Science (1)Toniiq (1)Revgenetics (1)Life Extension (1)
Consumer signals
17 products with consumer ratings 7 high-confidence signals 14,152 total consumer reviews
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