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Layer 1 · Decision
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Elysium Health

Cofactor

Connective tissue · Powder · 28 servings

Label snapshot

What the label says

What the product contains and what one serving costs, according to our catalog. Label amounts are not personal dose recommendations.

Ingredients listed
4 ingredients listed largest listed: Collagen Peptides 20 g
Form
Powder
List price (catalog, USD)
$75.00
Price per serving
$2.68List price divided by servings per container. A per-day cost only if the label serving is once daily.

Reading notes

  • Multi-ingredient product. Amounts are per ingredient per serving; the product is assessed as one bundle, not as a recommendation for each ingredient.
  • Vitamin amounts shown in µg/mg. Labels may use IU.
Full label record: servings, testing, ingredients
Servings per container
28
Catalog monthly estimate
$80.36
Testing disclosure
No third-party testing listedStatus as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Ingredients as listed

IngredientAmount per serving
Collagen Peptides20 g
NR250 mg
Hyaluronic Acid120 mg
Vitamin C90 mg

What to check on the label

  • Grams of collagen per scoop and how many scoops the label calls a serving. Flavoured powders carry more filler per gram.
  • The collagen source and type stated on the label. The catalog does not infer them.
  • Any added actives (hyaluronic acid, vitamin C, biotin) with their own amounts, listed below.

Amounts are per label serving as recorded in the catalog and are not a recommendation. Testing status reflects what the brand lists. Nothing here is medical advice.

Editorial score and research-dose calculations

These calculations describe our scoring method. They are not a recommended dose or proof of benefit from this product.

5.5/10
Overall score
#17 / 19 in Connective tissue

See the score breakdown below.

Read the evidence (3 studies)
Add to compareVisit brand site →
Watch out
Tier 3
Ingredient RCT (matching dose)
The ingredient was tested in an RCT at the same dose this product sells.
See the 3 supporting studies
  • Kawada 2015 (Hyaluronic Acid)120 mg/day HA improved skin hydration. Studied at 120 mg. This product: 120 mg.
  • Martens et al. 2018 (NR)6 weeks of 500 mg twice daily lowered systolic blood pressure in older adults with elevated BP. Studied at 500 mg. This product: 250 mg.
  • Dellinger et al. 2017 (NR)8 weeks at 100 to 1000 mg/day dose-dependently raised NAD+ in blood. Studied at 1000 mg. This product: 250 mg.
How we scored this product Show the full breakdown
Dose vs. studies (50%) Why 7.1 of 10. Primary ingredient is Collagen Peptides (evidence grade B). It delivers 20000 mg, above the studied range of 2500–15000 mg. Above the range docks the score because nobody has tested that much. Read the rule → 7.1
Transparency (20%) Why 5.0 of 10. Earned points for all doses disclosed. Lost points for no public certificate of analysis and no independent third-party testing. Read the rule → 5.0
Value (10%) Why 8.2 of 10. One day at the trial dose costs about $1.34. That is cheaper than average (148 of 313 by cost per effective day). Read the rule → 8.2
Formulation (10%) Why 5.0 of 10. No published absorption advantage or disadvantage on file. The default of 5 is not a criticism. Read the rule → 5.0 Default. No absorption data on file.
Safety (5%) Why 5.0 of 10. Baseline 5.0. Third-party testing adds 2.0. Public lab certificate adds 1.5. NSF, USP or Informed Choice certification adds 1.5. Active safety signal subtracts 3.0. Read the rule → 5.0
Community sentiment (5%) Why 7.5 of 10. No external reviews found, so community sentiment defaults to neutral. Community never counts as clinical evidence. Read the rule → 7.5
Composite How this 5.5 is built. 0.50 × 7.1 + 0.20 × 5.0 + 0.10 × 8.2 + 0.10 × 5.0 + 0.05 × 5.0 + 0.05 × 7.5 = 5.5 out of 10. Safety caps applied after. 5.5
5.5 composite
Dose vs. studies50%7.1
Transparency20%5.0
Value10%8.2
Formulation10%5.0
Safety5%5.0
Community5%7.5

Evidence gates dose: the evidence grade sets the ceiling, and the dose decides how much of that ceiling the product reaches. Value = inverse of price-per-trial-dose-day. Community = mean sentiment of external reviews. Safety caps applied after weighting.

This score is our editorial judgment, not a scientific standard. We combine published evidence, dose, price, transparency, and consumer signals into one composite: this is our method, not a peer-reviewed clinical rating. A higher score means a product does better on the factors we weight, not that it is medically proven to work.

Read the full method →

Editorial verdict

Quick verdict

5.5 / 10
Best for
Full trial dose
Avoid if
No public lab certificate, Premium pricing
Full-dose status
Meets trial dose
Price/month
$80
COA status
Not public
Biggest caveat
Vitamin C (90.0mg is 18% of the 500mg trial dose) is significantly under-dosed.
Nearest alternatives
Catalog snapshot. Check linked sources for current price, label and batch-specific testing.
Price verification
Current price: $75.00
Last price check: Sep 01, 2026
Add to compareVisit brand site →
Layer 2 · Context
In plain language

Why this scored this way

This Elysium Health Cofactor scores 6.5, making it a mid-tier product with both strengths and weaknesses. It delivers 90mg of Vitamin C, 45% of the studied range low edge (200mg) with grade A evidence (strong human trial data). The quality transparency (5.0) is limited by the lack of third-party testing.

What drives the score up

  • Dose-evidence score of 7.1 shows decent alignment with trial doses.
  • Collagen Peptides is dosed at the full research level with grade B evidence (promising human data, not yet comprehensive).
  • Collagen Peptides is also dosed at the full research level.

What drags it down

  • Vitamin C (90.0mg is 18% of the 500mg trial dose) is significantly under-dosed.
  • Collagen Peptides (20000.0mg is 200% of the 10000mg trial dose) is well above the trial dose. More is not always better.
  • No third-party testing, which caps the quality transparency.
  • Quality transparency of 5.0 is below the site average.

Why you'd choose it

  • You want a reasonably priced connective tissue product.
  • You want Vitamin C from a Elysium Health product.
  • You want doses that align with published research.

Why you might skip it

  • You want third-party verified purity.
  • You want a product with a publicly available CoA.
  • You need a full trial dose of vitamin c (this product under-doses it).
Question 1

Does the molecule work?

The science behind each active ingredient, independent of which brand sells it.

Collagen Peptides

Genuine benefits for skin and joint tissue at 10 g/day.

1 landmark RCT · US: Dietary supplement · EU: Food supplement
NR

The NAD+ precursor with the strongest safety file and EU approval.

2 landmark RCTs · US: GRAS, NDI accepted · EU: Authorised Novel Food (Commission Reg 2020/16)
Hyaluronic Acid

Skin hydration and joint comfort at 120 mg/day.

1 landmark RCT · US: Dietary supplement · EU: Food supplement
Vitamin C

Correcting deficiency is important; megadoses rarely add benefit.

4 landmark RCTs · US: Dietary supplement · EU: Food supplement

Full ingredient breakdown

Every active in this formula, its declared dose per serving, the dose used in the primary human trial, how much of that trial dose this product delivers, and the evidence grade for the ingredient itself.

IngredientDose / servingResearch dose% of researchEvidence grade
Collagen Peptides20000 mg10000 mg200%B
NR250 mg300 mg83%B
Hyaluronic Acid120 mg120 mg100%B
Vitamin C90 mg500 mg18%A

Percentages are dose per serving ÷ primary trial dose. Below 50% means the formula is unlikely to reproduce the trial outcome for that active. Grade A = multiple large human RCTs. Grade F = no human evidence. How grades work. Full glossary →

Question 2

Is this bottle good?

The specific product: dose, price, transparency, and what buyers report.

Dose vs research
800% of trial dose
Meets or exceeds the published effective dose
Cost at trial dose
$1.34/day at trial dose
What one effective daily dose actually costs
Transparency
5.0/10 · No public lab certificate
No third-party testing disclosed
Consumer signals
37 reviews across platforms · 4.2/5 · medium confidence
Operational signal only, never used as clinical evidence
Question 3

What's the catch?

Safety flags, transparency gaps, dosing concerns, and recurring buyer complaints.

!
Review advised
Dose at 800% of research dose
Safety flag
Dose at 800% of research dose
Dose or interaction risk detected. See ingredient page for details.
No public lab certificate
Certificate of Analysis not published
Without a public lab certificate, batch purity and potency cannot be independently verified.
No third-party testing
Independent lab verification not disclosed
The brand does not publish evidence of independent batch testing.
Overdose risk
Dose at 800% of trial dose
Far above the published effective dose. Check tolerable upper intake limits.
Buyer complaints
Trustpilot: Trouble canceling/pausing subscriptions; iHerb: Small sample size
Recurring themes from consumer review platforms.
Plain English

What’s inside

The main ingredients of this product, in plain language.

Collagen Peptides20000 mgEvidence B

Genuine benefits for skin and joint tissue at 10 g/day.

Read about Collagen Peptides →
NR250 mgEvidence B

The NAD+ precursor with the strongest safety file and EU approval.

Read about NR →
Hyaluronic Acid120 mgEvidence B

Skin hydration and joint comfort at 120 mg/day.

Read about Hyaluronic Acid →
Vitamin C90 mgEvidence A

Correcting deficiency is important; megadoses rarely add benefit.

Read about Vitamin C →
Layer 3 · Evidence vault

Product data & verification

Hard numbers and independently checked status. Expand each block for its source.

The numbers

Price
$75
per bottle · 28 servings
Dose vs. research
Above trial dose 800%
of published effective dose
$ / day at studied dose
$1.34
what one effective daily dose costs
$ / g active
$0.13
per gram of active substance
Independently checked

Data verification

COA status
Not public
Evidence grade
BBBA
Per-ingredient breakdown
BCollagen Peptides
BNR
BHyaluronic Acid
AVitamin C

All product data is checked against original sources. Prices, doses, and testing status are updated when product pages change. Evidence grades are reviewed when new human RCTs are published. Read how we verify.

What's inside

Ingredient
Dose in this product
Trial dose
Evidence
Collagen Peptides
Genuine benefits for skin and joint tissue at 10 g/day.
Choi et al. 2019
20000 mg 200% of trial dose
10000 mg
NR
The NAD+ precursor with the strongest safety file and EU approval.
Martens et al. 2018Dellinger et al. 2017
250 mg 83% of trial dose
300 mg
Hyaluronic Acid
Skin hydration and joint comfort at 120 mg/day.
Kawada 2015
120 mg 100% of trial dose
120 mg
90 mg 18% of trial dose
500 mg
3.9 /5
Medium confidence
37 reviews across 3 platforms (3 sources)
Source diversity: 69%
RedditTrustpilotiHerb
PraiseProducts make users feel betterHigh perceived quality
ComplaintsTrouble canceling/pausing subscriptionsSmall sample size
Last checked: 2026-08-23

Consumer signals

4.21 out of 5 across 37 verified reviews on 3 platforms.

Medium confidence

Consumer sentiment compiled from 3 public sources.

Trustpilot

15 reviews · 3.2/5 · mixed sentiment

PraiseProducts make users feel better
ComplaintsTrouble canceling/pausing subscriptions
Themes

Elysium Health's Trustpilot rating is middling, driven down by subscription cancellation complaints despite positive product feedback.

Compiled from Trustpilot listing located during research; verified at build time.

iHerb

22 reviews · 4.9/5 · positive sentiment

PraiseHigh perceived qualityGood taste (unflavored)
ComplaintsSmall sample size
Themes

iHerb reviewers rate Elysium Cofactor very highly, though based on a small number of ratings.

Compiled from iHerb listing located during research; verified at build time.

Reddit

3 threads discussed · mixed sentiment

PraiseInterest in NAD+/cellular health claims
ComplaintsSkepticism about scientific proof and price
Themes

r/longevity and r/askscience threads express skepticism about Elysium's anti-aging claims despite general interest in the product line.

Compiled from Reddit listing located during research; verified at build time.

These are consumer sentiment signals. They do not measure whether the product actually works. See our evidence section for that.

What others say (unverified)

No external reviews aggregated yet for this product.

Layer 3 · Evidence vault

Evidence, claims & regulation

Published evidence, claim checks, regulatory status and what could not be verified.

Evidence

Research behind this product

The studies that established the trial dose and evidence grade for each active ingredient in this product. Click through to read the original paper.

Collagen PeptidesChoi et al. 2019
NRMartens et al. 2018
NRDellinger et al. 2017
Hyaluronic AcidKawada 2015
Vitamin CVitamin C umbrella review 2022 (76 meta-analyses)
Vitamin CVitamin C + telomere length 2023 (NHANES)
Vitamin CVitamin C and CVD 2020 (Antioxidants)
Vitamin CCochrane: Vitamin C for common cold
Important to know
Collagen PeptidesAdding vitamin C boosts collagen synthesis. Cold water dissolves poorly, mix in warm liquid.
NRAlmost all commercial NR uses licensed Niagen® from ChromaDex. If a product doesn't say Niagen, ask why.
Hyaluronic AcidMW matters for absorption; look for <10 kDa marketing.
Vitamin CHigh doses cause GI upset. Buffered forms gentler. Liposomal marketing typically overstated for chronic use.

Editorial notes

A collagen peptide powder (20g/scoop, in line with typical collagen doses) stacked with Elysium's standard 250mg NR dose, 120mg hyaluronic acid, and 90mg vitamin C. Reasonable ingredient logic for skin/joint support with an NAD+ angle, priced at the premium end of collagen powders ($2.68/serving).

Go deeper

Where this sits

Actives inside
Collagen PeptidesNRHyaluronic AcidVitamin C
Category
See all in Connective tissue →
Ranking
See top 10 NR supplements →
Brand
Elysium Health profile →
Add to compare Visit brand site →
Brand owners

Spot an error?

If you are the manufacturer or brand owner of Cofactor and believe any data on this page is incorrect (wrong dose, wrong ingredient, wrong price, missing certification, outdated status), you can request a correction.

We review every request, verify it against primary sources, and publish any accepted change with a dated note. Corrections from brand owners are treated the same as corrections from anyone else: verified before they move.

Request a correction →
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EPA/DHA split not stored

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Basis
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Ingredients listed
2 ingredients listedlargest listed: NR 250 mg
Price per serving
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Testing
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Multi-ingredient bundle

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Format
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Ingredients listed
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