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Amino acid / Longevity

Taurine · Taurine

The 2023 sensation; species-wide lifespan extension in mice, humans unproven.

D
Evidence grade
Mostly animal
Strongest study
Tier 2 · 2 linked studies

Short answer

Interesting but early. If you take it, 3 to 6 g/day (not the marketing 500 mg) is closer to what mouse studies suggest, scaled down.

Product and dose overview

Taurine (Taurine) is a amino acid / longevity with evidence grade D, meaning it is primarily supported by animal studies. We track 7 products containing Taurine. Typical doses range from 1000 to 3000 mg per serving. The top-ranked product scores 6.7 out of 10 on our composite scale (dose, evidence, price, testing, transparency). Prices range up to $159.00 per month.

Evidence grade: D Products in database: 7 Category: Amino acid / Longevity

Top Taurine products

ProductBrandDosePrice/mo3rd-party testedScore
Longevity Mix - Blood OrangeBlueprint1000 mg$49.00Yes6.7
Daily Ultimate LongevityIM82000 mg$149.00Yes6.3
Taurine PowderBulkSupplements3000 mg$25.00Yes6.0
L-Taurine SupplementDouble Wood Supplements1000 mg$19.95Yes6.0
Longevity BundleTmrw1200 mg$159.00Yes5.4

Scores are editorial judgments, not a scientific standard. See how we score.

What it is

A sulfur-containing amino acid your body makes and that's abundant in meat and shellfish. Blood levels drop with age. A 2023 Nature paper caused a stir by showing taurine supplementation extended lifespan in mice and monkeys.

Why people take it

Yadav et al. 2023 (Science) showed 3 to 6 g/kg body weight (huge doses) extended mouse lifespan ~10% and improved multiple aging markers. Human data limited to biomarker studies. Human dose extrapolation is uncertain.

Our verdict

Interesting but early. If you take it, 3 to 6 g/day (not the marketing 500 mg) is closer to what mouse studies suggest, scaled down.

Structure & class

2-aminoethanesulfonic acid. Non-proteinogenic amino sulfonic acid.

Mechanism & clinical data

Yadav et al. 2023 (Science) demonstrated ~10% lifespan extension in mice at 1 g/kg. Human interventions on aging biomarkers ongoing. Rodent-to-human dose translation controversial.

Pharmacokinetics

~1 hour.

Dose & forms

Trial dose
3000 mg
/ day
Range in trials
1000 to 6000 mg
/ day
Common forms
Powder (cheapest), Capsule

What to watch out for

Very cheap in powder form; capsules charge a premium for the same molecule.

Safety limits and interactions

When a product exceeds the UL or contains an ingredient with clinically significant interactions, a "Review advised" flag appears on its product page and links here.

Safety note
No formal UL from FNB/NIH. EFSA identified an Observed Safe Level of 6,000 mg/day based on studies up to one year without adverse effects; typical supplement doses of 1-6 g/day are considered safe.

Source: https://www.fda.gov/files/food/published/GRAS-Notice-000586---Taurine.pdf

Where this dose comes from

The trial dose above is our editorial pick from the published human trials for this ingredient. We choose the dose that the best-available studies used on the endpoint most relevant to longevity. The range shows the lowest and highest doses tested in published trials. The landmark studies below are the papers we read to set it. You can click through and check our work.

When new trials publish, our automated sweeps flag them. If a new study materially changes the dose, we update it through editorial review and record the old dose, new dose, and the triggering study in every affected product's recommendation history. The dose is never changed automatically.

Regulatory status

EUFood supplement
USDietary supplement
UKFood supplement
CANHP

Timeline

Regulatory events, evidence grade changes, and key research milestones for Taurine, most recent first. Studies link to the paper; regulatory entries name and link the responsible authority.

  • 2026 Research milestone
    Beine et al. 2026 (Food & Function)
    Comprehensive review of taurine roles in antioxidant defense, anti-inflammatory signaling, calcium regulation, and mitochondrial function. Confirms promising human supplementation outcomes. Notes 2025 NIH finding that taurine does not longitudinally decline with age in humans.
    Source →
  • 2025-04 Regulatory single source
    EU Court sharpens the bar for botanical health claims
    A Court of Justice of the European Union ruling in April 2025 further tightened the requirements for how botanical ingredients (herbs, plant extracts) can be marketed with health claims in the EU, effectively removing much of the flexibility of the on-hold list.
  • 2024-06 Regulatory confirmed
    EU report identifies 117 supplement substances as potential health risks
    The HoA Working Group on Food Supplements (26 European countries) published its first report evaluating 117 substances used in food supplements. Of these, 65 were assessed as likely novel foods, 6 were already regulated, 34 had insufficient data, and 12 were prioritized for Article 8 restriction under Regulation (EC) No 1925/2006. The 12 priority substances include ashwagandha, curcumin, melatonin, piperine, St. John's wort, coumarin, p-synephrine, maca, holy basil, Melaleuca, black cohosh, and L-tryptophan. The report drew on 1,500 RASFF alerts reviewed between 2017 and mid-2022.
    Source →
  • 2023 Research milestone
    Yadav et al. 2023 (Science)
    Taurine supplementation extended lifespan in mice and improved aging biomarkers in monkeys and humans.
    Source →
  • 2009-02 Regulatory confirmed
    EFSA confirms taurine in energy drinks is not a safety concern
    EFSA's ANS Panel published a scientific opinion confirming that taurine as an ingredient in energy drinks is not of safety concern at current intake levels. The NOAEL was established at 1,000 mg/kg body weight/day. The opinion resolved outstanding concerns raised by the EU Scientific Committee on Food in 2003 about potential harmful effects of taurine on the brain.
    Source →
  • 2006-12 Regulatory confirmed
    EU Health Claims Regulation adopted
    Regulation (EC) No 1924/2006 laid down harmonised rules for nutrition and health claims made on foods, including supplements. Only claims listed in the EU Register of authorised claims can be used. Rejected botanical claims are held in a separate on-hold list.
    Source →
  • 1997 Regulatory confirmed
    EU introduces the Novel Food Regulation
    Regulation (EC) No 258/97 required any food or food ingredient without a history of consumption in the EU before 15 May 1997 to be authorised before being placed on the market. This is the framework that captures NMN, spermidine as a supplement ingredient, urolithin A, and many other longevity actives.
    Source →
2026 evidence refresh

Taurine is an amino acid that supports heart muscle function and glucose metabolism, but its 2023 aging-biomarker claim did not hold up.

Verified 2026-08-06. We update this section as new peer-reviewed trials land.

Human RCT base
40+
peer-reviewed randomised trials
Largest single trial
n = 1024
Taurine supplementation significantly reduced systolic blood pressure, diastolic blood pressure, fasting blood glucose, and triglycerides across 25 pooled RCTs. source

Best-supported claim

Taurine's best-supported human effects are on cardiometabolic markers and heart failure symptoms. A 2025 meta-analysis of 34 RCTs found taurine significantly reduced fasting blood glucose, HbA1c, fasting insulin, HOMA-IR, triglycerides, and total cholesterol, with the strongest glucose and lipid effects at 1.5-3.0 g/day for 8 or more weeks (https://academic.oup.com/nutritionreviews/advance-article/doi/10.1093/nutrit/nuaf220/8340615). A separate 2024 meta-analysis of 20 RCTs and 808 participants found taurine reduced heart rate, systolic and diastolic blood pressure, and NYHA heart failure functional class, while increasing left ventricular ejection fraction, with the largest benefits in heart failure patients specifically (https://pmc.ncbi.nlm.nih.gov/articles/PMC11325608/). For exercise, a meta-analysis found oral taurine produced a small but real improvement in endurance performance (Hedges' g=0.40) regardless of whether it was taken as a single 1 g dose or 6 g/day for 2 weeks.

Not supported by the evidence base

Taurine was propelled into the longevity supplement conversation by a 2023 Science paper (Singh et al.) reporting taurine declines with age across species and that supplementation extended mouse lifespan by 10-12%, with only correlational human data. A rigorous 2025 follow-up in the same journal, using longitudinal data from three distinct human cohorts plus nonhuman primates and mice, directly contradicted the premise: circulating taurine increased or stayed unchanged with age in healthy individuals, and there was no clear association between taurine levels and health status (https://www.science.org/doi/10.1126/science.adl2116). The 2025 paper concluded that individual variability in taurine levels is generally larger than any change across the lifespan, meaning taurine is unlikely to be a useful aging biomarker, let alone a proven anti-aging intervention in humans. No completed human RCT has tested whether taurine supplementation extends lifespan or slows biological aging; a German trial (TauAge) testing 4 g/day for 6 months on biological age markers was still recruiting as of its registration.

Typical dose

500 mg to 3 g/day, with cardiometabolic benefits concentrated at 1.5-3 g/day taken for 8 weeks or longer

Safety

Taurine has a strong safety record across the dozens of RCTs reviewed, including in heart failure patients receiving standard medical treatment. The 2024 metabolic syndrome meta-analysis found no significant difference in adverse effect rates between taurine and control groups (odds ratio 1.48, not significant) (https://pubmed.ncbi.nlm.nih.gov/38755142/). Doses used in trials range from 0.5 to 6 g/day without safety signals. Long-term safety data beyond one year in the general population remains limited.

Interactions worth flagging

  • lithium
  • blood pressure medications

Three recent studies to know

  • Is taurine an aging biomarker?
    Science 2025

    Read study →
  • Insights into the cardiovascular benefits of taurine
    PMC (peer-reviewed cardiology journal) 2024

    Read study →
  • Effects of Oral Taurine Supplementation on Cardiometabolic Risk Factors
    Nutrition Reviews 2025

    Read study →

Landmark studies

Found in these products (7)

All products in our catalog that contain Taurine, ranked by our overall score. Ranking is editorial, never paid.

Longevity stack
Ingredients listed
6 ingredients listedlargest listed: Creatine 2,500 mg
Price per serving
$1.63$49.00 · 30 servings
Testing
3rd-party listed · no public lab certificate

Multi-ingredient bundle

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.7/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

83%
of trial dose
$3.27
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with blueprint.bryanjohnson.com
Longevity stack
Ingredients listed
9 ingredients listedlargest listed: Glycine 3,000 mg
Price per serving
$4.97$149.00 · 30 servings
Testing
3rd-party listed · no public lab certificate

Multi-ingredient bundle

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.3/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$4.97
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with im8health.com
BulkSupplements
Taurine Powder
Amino acid
Active per serving
Taurine 3,000 mgPowder · 100 servings
Price per serving
$0.25$25.00 · 100 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.0/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.25
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with www.bulksupplements.com
Double Wood Supplements
L-Taurine Supplement
Amino acid
Active per serving
Taurine 1,000 mgCapsule · 90 servings
Price per serving
$0.22$19.95 · 90 servings
Testing
3rd-party listed · public lab certificate

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 6.0/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$0.66
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with doublewoodsupplements.com
Longevity stack
Ingredients listed
7 ingredients listedlargest listed: Taurine 1,200 mg
Price per serving
$5.30$159.00 · 30 servings
Testing
3rd-party listed · no public lab certificate

Multi-ingredient bundle

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 5.4/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$5.30
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with drinktmrw.com
Amino acid
Active per serving
Taurine 2,100 mgCapsule · 30 servings
Price per serving
$1.16$34.90 · 30 servings
Testing
None listed

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 5.0/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$1.66
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with drnoel.com
NOVOS Labs
NOVOS Bar
Multi/greens
Ingredients listed
3 ingredients listedlargest listed: Taurine 1,500 mg
Price per serving
$4.00$48.00 · 12 servings
Testing
None listed

Multi-ingredient bundle

Status as recorded in the catalog from brand materials; not independently verified by NO1GEVITY.

Score & research context 4.8/10

Editorial score, not proof that this product works. Research-dose calculations are not dosing advice.

100%
of trial dose
$8.00
per research-dose day, not label serving
0Trial dose2×
Catalog price · Confirm current price with novoslabs.com
Editorial guides

Buying guides and comparisons

Neighbouring molecules

Related ingredients

See all in Amino acid / Longevity →

Molecules in the same class, plus the actives most often formulated alongside Taurine in our catalogue.

Ca-AKGDstacked together in 2 productsGlycineBstacked together in 2 productsNMNBstacked together in 2 productsAstaxanthinBstacked together in 2 productsSpermidineCstacked together in 2 productsCreatineAstacked together in 1 productL-TheanineBstacked together in 1 productHyaluronic AcidBstacked together in 1 product
Product shelves
See all in Longevity stack (3)See all in Amino acid (3)See all in Multi/greens (1)

See Taurine in context: the mechanism it acts through, the biomarker it moves, the products that dose it, and the trials that tested it.

View Taurine on the Longevity Map →

Frequently asked questions

What is Taurine?

A sulfur-containing amino acid your body makes and that's abundant in meat and shellfish. Blood levels drop with age. A 2023 Nature paper caused a stir by showing taurine supplementation extended lifespan in mice and monkeys.

What dose of Taurine should I take?

The trial dose in published human studies is 3000 mg per day, with a range of 1000 to 6000 mg per day. Always consult a qualified clinician before starting any supplement.

Is Taurine safe?

No formal UL from FNB/NIH. EFSA identified an Observed Safe Level of 6,000 mg/day based on studies up to one year without adverse effects; typical supplement doses of 1-6 g/day are considered safe.

What is the best Taurine supplement?

We track 7 products containing Taurine. The top-ranked product scores 6.7 out of 10 on our composite scale, which evaluates dose, evidence, price, third-party testing, and transparency. See the comparison table above. Scores are editorial judgments, not a scientific standard.

What is the evidence grade for Taurine?

Taurine has evidence grade D, meaning it is primarily supported by animal studies. Grade A means replicated human RCTs with hard endpoints. Grade B means human RCTs with biomarker outcomes. Grade C means mixed or small human trials. See our evidence grading methodology.

Independently checked

Data verification

Evidence grade
D
Mostly animal
Research dose
3000 mg
Products tracked
7
Updated continuously
Safety signal
No formal UL from FNB/NIH. EFSA identified an Observed Sa...

Evidence grades are reviewed when new human RCTs are published. Product counts update automatically as new products are added. Dose ranges reflect published trial data, not brand recommendations. Read how we verify.